iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059706

UUCD1 version

UUC-MeG-00346

Ensembl Protein ID

ENSMGAP00000007292.2

UniProt Accession

G1N5P0; G1N5P0_MELGA

Protein Name

Uncharacterized protein

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000007184.2	ENSMGAT00000008063.2	ENSMGAP00000007292.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.30e-06	25.8	196	237

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle +   ++++v pC H fh++C+  w        ++ +CP Cr
   Q: 196  CAICLEKYidGEELRVIPCTHRFHKKCVDPW------LLQHHTCPHCR 237
           ********66334******************......9999******8 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

LFQMHPLGLC NSNDEEDLYE YGWVGVVKLE QPELEPKPCL TVLGKAKRAV QRGATAVIFD 60
VSENPDAIDQ LNQGLEDPLK RPVVYVKGAD AVKLMNIVNK QKVARARIQH RPPRQPTEYF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTTTCAGA TGCATCCACT CGGACTGTGT AATAGCAATG ATGAGGAAGA CCTGTATGAA 60
TATGGCTGGG TAGGAGTGGT GAAGCTGGAA CAGCCTGAGC TGGAACCAAA GCCATGCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	71.59	0.00e+00	999.00
IUUC-Apl-004188	Anas platyrhynchos	95.31	0.00e+00	1493.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	3.00e-15	73.60
IUUC-Ath-007372	Arabidopsis thaliana	42.17	3.00e-15	73.90
IUUC-Ame-011764	Astyanax mexicanus	65.42	0.00e+00	772.00
IUUC-Bta-012478	Bos taurus	59.45	1.00e-131	463.00
IUUC-Bol-015945	Brassica oleracea	44.00	6.00e-15	74.30
IUUC-Bra-017899	Brassica rapa	44.00	7.00e-15	74.30
IUUC-Cja-019504	Callithrix jacchus	73.05	0.00e+00	1060.00
IUUC-Cfa-020048	Canis familiaris	71.46	0.00e+00	1019.00
IUUC-Cpo-021725	Cavia porcellus	68.08	0.00e+00	964.00
IUUC-Csa-023586	Chlorocebus sabaeus	72.29	0.00e+00	1003.00
IUUC-Cho-024867	Choloepus hoffmanni	83.42	4.00e-177	614.00
IUUC-Cin-025569	Ciona intestinalis	48.56	9.00e-58	217.00
IUUC-Csv-025869	Ciona savignyi	46.50	5.00e-52	198.00
IUUC-Dre-027553	Danio rerio	66.23	0.00e+00	842.00
IUUC-Dno-029370	Dasypus novemcinctus	71.34	0.00e+00	985.00
IUUC-Dor-030816	Dipodomys ordii	67.60	0.00e+00	930.00
IUUC-Ete-033060	Echinops telfairi	66.41	0.00e+00	733.00
IUUC-Eca-034044	Equus caballus	72.57	0.00e+00	1045.00
IUUC-Eeu-034591	Erinaceus europaeus	53.31	1.00e-100	360.00
IUUC-Fca-036000	Felis catus	73.22	0.00e+00	1041.00
IUUC-Fal-037147	Ficedula albicollis	91.74	0.00e+00	1431.00
IUUC-Gmo-039099	Gadus morhua	64.02	3.00e-122	431.00
IUUC-Gga-041243	Gallus gallus	99.43	0.00e+00	1325.00
IUUC-Gac-041340	Gasterosteus aculeatus	53.03	1.00e-129	456.00
IUUC-Gma-044387	Glycine max	53.06	1.00e-14	72.40
IUUC-Ggo-044953	Gorilla gorilla	72.85	0.00e+00	1029.00
IUUC-Hsa-046484	Homo sapiens	72.88	0.00e+00	1041.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	71.48	0.00e+00	1020.00
IUUC-Lch-050004	Latimeria chalumnae	63.12	0.00e+00	761.00
IUUC-Loc-051830	Lepisosteus oculatus	66.15	0.00e+00	855.00
IUUC-Laf-053975	Loxodonta africana	71.20	0.00e+00	992.00
IUUC-Mcc-055302	Macaca mulatta	71.69	0.00e+00	987.00
IUUC-Meu-056263	Macropus eugenii	74.72	0.00e+00	793.00
IUUC-Mtr-058744	Medicago truncatula	40.66	1.00e-13	68.90
IUUC-Mmr-061372	Microcebus murinus	71.62	0.00e+00	976.00
IUUC-Mdo-062651	Monodelphis domestica	63.94	0.00e+00	875.00
IUUC-Mmu-064339	Mus musculus	71.98	0.00e+00	988.00
IUUC-Mac-064852	Musa acuminata	54.55	2.00e-13	70.50
IUUC-Mpu-066211	Mustela putorius furo	70.04	0.00e+00	995.00
IUUC-Mlu-067058	Myotis lucifugus	71.03	0.00e+00	941.00
IUUC-Nle-069886	Nomascus leucogenys	72.42	0.00e+00	1021.00
IUUC-Opr-070218	Ochotona princeps	68.45	0.00e+00	885.00
IUUC-Ont-072483	Oreochromis niloticus	62.79	0.00e+00	833.00
IUUC-Oan-073718	Ornithorhynchus anatinus	70.82	0.00e+00	912.00
IUUC-Ocu-073847	Oryctolagus cuniculus	66.79	0.00e+00	849.00
IUUC-Ogl-077034	Oryza glaberrima	45.71	7.00e-12	64.30
IUUC-Ogu-078680	Oryza glumaepatula	45.71	3.00e-12	65.50
IUUC-Oin-079182	Oryza indica	45.71	4.00e-12	65.10
IUUC-Ome-081485	Oryza meridionalis	45.71	3.00e-12	65.50
IUUC-Oni-082249	Oryza nivara	45.71	4.00e-12	65.10
IUUC-Opu-083745	Oryza punctata	43.33	2.00e-12	66.60
IUUC-Oru-084953	Oryza rufipogon	45.71	5.00e-12	64.70
IUUC-Osa-085734	Oryza sativa	45.71	5.00e-12	64.70
IUUC-Ola-087358	Oryzias latipes	66.06	0.00e+00	824.00
IUUC-Oga-088362	Otolemur garnettii	72.16	0.00e+00	1040.00
IUUC-Oar-090197	Ovis aries	89.81	2.00e-94	338.00
IUUC-Ptr-091350	Pan troglodytes	72.64	0.00e+00	1039.00
IUUC-Pan-091700	Papio anubis	71.31	0.00e+00	980.00
IUUC-Psi-093301	Pelodiscus sinensis	82.05	0.00e+00	1262.00
IUUC-Pfo-096917	Poecilia formosa	66.45	0.00e+00	820.00
IUUC-Pab-097932	Pongo abelii	72.78	0.00e+00	1058.00
IUUC-Pop-099512	Populus trichocarpa	53.06	3.00e-14	70.90
IUUC-Pca-101054	Procavia capensis	81.94	0.00e+00	840.00
IUUC-Ppe-101991	Prunus persica	32.43	9.00e-14	69.30
IUUC-Pva-102879	Pteropus vampyrus	72.76	0.00e+00	1028.00
IUUC-Sha-106507	Sarcophilus harrisii	53.90	2.00e-174	605.00
IUUC-Sit-110656	Setaria italica	65.12	7.00e-13	66.20
IUUC-Sar-113182	Sorex araneus	81.23	2.00e-107	383.00
IUUC-Sbi-114132	Sorghum bicolor	50.00	1.00e-11	62.40
IUUC-Ssc-115966	Sus scrofa	67.26	0.00e+00	858.00
IUUC-Tgu-116864	Taeniopygia guttata	88.71	0.00e+00	1063.00
IUUC-Tru-118502	Takifugu rubripes	64.69	0.00e+00	800.00
IUUC-Tsy-119210	Tarsius syrichta	74.64	0.00e+00	985.00
IUUC-Tni-120344	Tetraodon nigroviridis	56.80	6.00e-144	503.00
IUUC-Tca-121477	Theobroma cacao	46.30	1.00e-13	69.70
IUUC-Tbe-127735	Tupaia belangeri	69.85	5.00e-105	375.00
IUUC-Ttr-128714	Tursiops truncatus	63.09	0.00e+00	803.00
IUUC-Vvi-131731	Vitis vinifera	48.98	3.00e-13	67.80
IUUC-Xtr-132280	Xenopus tropicalis	59.95	0.00e+00	719.00
IUUC-Xma-134192	Xiphophorus maculatus	66.58	0.00e+00	823.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence