iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073847

UUCD1 version

UUC-OrC-00347

Ensembl Protein ID

ENSOCUP00000022774.2

UniProt Accession

G1U096; G1U096_RABIT

Protein Name

Uncharacterized protein

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000009684.3	ENSOCUT00000025667.2	ENSOCUP00000022774.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	80.76	0.00e+00	1066.00	IUUC-Hsa-046484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MHPLGLCNNN DEEDLYEYGW VGVVKLEQPE LDPKPCLTVL GKAKRAVQRG ATAVIFDVSE 60
NPEAIDQLNQ GLEDPLKRPV VYVKGADAIK LMNIVNKQKV ARARIQHRPP RQPTEYFDMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCATTTCTA ATGGTTTCTC CAGGAAGCCC TAGATGCATA CCCAGGTACA CTTGCTTAAG 60
TGGAAGTAGT TGATATTGTT AAGATCTGAA GGCCAAACAA GACTTGGCTA CTAACCTAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	77.43	0.00e+00	1083.00
IUUC-Apl-004188	Anas platyrhynchos	67.61	0.00e+00	924.00
IUUC-Aly-005850	Arabidopsis lyrata	35.37	3.00e-12	63.90
IUUC-Ame-011764	Astyanax mexicanus	59.72	0.00e+00	708.00
IUUC-Bta-012478	Bos taurus	58.15	3.00e-161	561.00
IUUC-Cja-019504	Callithrix jacchus	79.93	0.00e+00	1160.00
IUUC-Cfa-020048	Canis familiaris	80.86	0.00e+00	1164.00
IUUC-Cpo-021725	Cavia porcellus	73.95	0.00e+00	1066.00
IUUC-Csa-023586	Chlorocebus sabaeus	80.92	0.00e+00	1135.00
IUUC-Cho-024867	Choloepus hoffmanni	85.19	0.00e+00	639.00
IUUC-Cin-025569	Ciona intestinalis	46.28	1.00e-52	201.00
IUUC-Csv-025869	Ciona savignyi	44.26	6.00e-48	185.00
IUUC-Dre-027553	Danio rerio	61.43	0.00e+00	766.00
IUUC-Dno-029370	Dasypus novemcinctus	78.03	0.00e+00	1063.00
IUUC-Dor-030816	Dipodomys ordii	74.08	0.00e+00	996.00
IUUC-Ete-033060	Echinops telfairi	72.33	0.00e+00	783.00
IUUC-Eca-034044	Equus caballus	80.98	0.00e+00	1173.00
IUUC-Eeu-034591	Erinaceus europaeus	61.48	9.00e-124	437.00
IUUC-Fca-036000	Felis catus	82.30	0.00e+00	1170.00
IUUC-Fal-037147	Ficedula albicollis	69.13	0.00e+00	939.00
IUUC-Gmo-039099	Gadus morhua	51.84	5.00e-116	411.00
IUUC-Gga-041243	Gallus gallus	60.41	0.00e+00	704.00
IUUC-Gac-041340	Gasterosteus aculeatus	50.17	4.00e-110	391.00
IUUC-Gma-044387	Glycine max	45.16	6.00e-14	70.50
IUUC-Ggo-044953	Gorilla gorilla	82.08	0.00e+00	1172.00
IUUC-Hsa-046484	Homo sapiens	81.01	0.00e+00	1177.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	79.21	0.00e+00	1147.00
IUUC-Lch-050004	Latimeria chalumnae	56.28	0.00e+00	637.00
IUUC-Loc-051830	Lepisosteus oculatus	62.60	0.00e+00	743.00
IUUC-Laf-053975	Loxodonta africana	75.68	0.00e+00	1107.00
IUUC-Mcc-055302	Macaca mulatta	79.98	0.00e+00	1122.00
IUUC-Meu-056263	Macropus eugenii	71.32	0.00e+00	736.00
IUUC-Mtr-058744	Medicago truncatula	36.26	6.00e-12	63.50
IUUC-Mga-059706	Meleagris gallopavo	69.67	0.00e+00	936.00
IUUC-Mmr-061372	Microcebus murinus	77.69	0.00e+00	1108.00
IUUC-Mdo-062651	Monodelphis domestica	64.02	0.00e+00	834.00
IUUC-Mmu-064339	Mus musculus	75.75	0.00e+00	1080.00
IUUC-Mac-064877	Musa acuminata	29.80	4.00e-13	68.60
IUUC-Mpu-066211	Mustela putorius furo	78.16	0.00e+00	1100.00
IUUC-Mlu-067058	Myotis lucifugus	78.47	0.00e+00	1070.00
IUUC-Nle-069886	Nomascus leucogenys	81.12	0.00e+00	1144.00
IUUC-Opr-070218	Ochotona princeps	81.99	0.00e+00	1073.00
IUUC-Ont-072483	Oreochromis niloticus	58.61	0.00e+00	731.00
IUUC-Oan-073718	Ornithorhynchus anatinus	67.46	0.00e+00	857.00
IUUC-Ola-087358	Oryzias latipes	60.53	0.00e+00	728.00
IUUC-Oga-088362	Otolemur garnettii	78.80	0.00e+00	1152.00
IUUC-Oar-090197	Ovis aries	92.39	5.00e-89	322.00
IUUC-Ptr-091350	Pan troglodytes	81.01	0.00e+00	1176.00
IUUC-Pan-091700	Papio anubis	80.21	0.00e+00	1116.00
IUUC-Psi-093301	Pelodiscus sinensis	67.74	0.00e+00	907.00
IUUC-Pfo-096917	Poecilia formosa	60.08	0.00e+00	729.00
IUUC-Pab-097932	Pongo abelii	80.66	0.00e+00	1174.00
IUUC-Pop-099512	Populus trichocarpa	38.14	2.00e-13	68.20
IUUC-Pca-101054	Procavia capensis	87.17	0.00e+00	882.00
IUUC-Pva-102879	Pteropus vampyrus	80.02	0.00e+00	1142.00
IUUC-Sha-106507	Sarcophilus harrisii	52.40	4.00e-159	555.00
IUUC-Sar-113182	Sorex araneus	77.39	2.00e-104	373.00
IUUC-Ssc-115966	Sus scrofa	75.03	0.00e+00	965.00
IUUC-Tgu-116864	Taeniopygia guttata	62.03	2.00e-173	602.00
IUUC-Tru-118502	Takifugu rubripes	59.55	0.00e+00	710.00
IUUC-Tsy-119210	Tarsius syrichta	78.91	0.00e+00	1116.00
IUUC-Tni-120344	Tetraodon nigroviridis	51.46	6.00e-117	414.00
IUUC-Tbe-127735	Tupaia belangeri	77.51	2.00e-122	433.00
IUUC-Ttr-128714	Tursiops truncatus	70.31	0.00e+00	925.00
IUUC-Xtr-132280	Xenopus tropicalis	58.96	0.00e+00	669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence