iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097932

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01152648

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000011679.2	ENSPPYT00000013559.2	ENSPPYP00000013028.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.50	0.00e+00	1489.00	IUUC-Hsa-046484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MIYKTDLPQE SQGRWGWMEC VPAGTSALGQ AQWGKPRWIH YGPALMIGMH PLGLCNNNDE 60
EDLYEYGWVG VVKLEQPELD PKPCLTVLGK AKRAVQRGAT AVIFDVSENP EAIDQLNQGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGGGTTTAT TTATTGGTTT TTAGTACCTT TTATTCTACT TATAAAAGTA ATACATGTTG 60
ATTGTAGAAA ACTTGGAAAA TTAAAAAGCA AACCAAAAAG AAAATGAAAA TCACCTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	86.01	0.00e+00	1234.00
IUUC-Apl-004188	Anas platyrhynchos	71.98	0.00e+00	1059.00
IUUC-Aca-004606	Anolis carolinensis	37.06	7.00e-28	117.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	3.00e-15	74.30
IUUC-Ath-007372	Arabidopsis thaliana	42.68	2.00e-14	71.60
IUUC-Ame-011764	Astyanax mexicanus	63.23	0.00e+00	736.00
IUUC-Bta-012478	Bos taurus	66.58	0.00e+00	663.00
IUUC-Bol-016217	Brassica oleracea	56.25	3.00e-14	70.50
IUUC-Bra-017407	Brassica rapa	56.25	3.00e-14	70.50
IUUC-Cja-019504	Callithrix jacchus	95.80	0.00e+00	1469.00
IUUC-Cfa-020048	Canis familiaris	88.04	0.00e+00	1317.00
IUUC-Cpo-021725	Cavia porcellus	81.55	0.00e+00	1196.00
IUUC-Csa-023586	Chlorocebus sabaeus	95.73	0.00e+00	1413.00
IUUC-Cho-024867	Choloepus hoffmanni	92.70	0.00e+00	692.00
IUUC-Cin-025569	Ciona intestinalis	47.11	2.00e-55	210.00
IUUC-Csv-025869	Ciona savignyi	45.04	5.00e-49	188.00
IUUC-Dre-027553	Danio rerio	65.47	0.00e+00	803.00
IUUC-Dno-029370	Dasypus novemcinctus	85.56	0.00e+00	1234.00
IUUC-Dor-030816	Dipodomys ordii	81.54	0.00e+00	1148.00
IUUC-Ete-033060	Echinops telfairi	76.10	0.00e+00	862.00
IUUC-Eca-034044	Equus caballus	89.08	0.00e+00	1316.00
IUUC-Eeu-034591	Erinaceus europaeus	68.10	3.00e-137	482.00
IUUC-Fca-036000	Felis catus	88.12	0.00e+00	1311.00
IUUC-Fal-037147	Ficedula albicollis	71.58	0.00e+00	1071.00
IUUC-Gmo-039099	Gadus morhua	49.91	1.00e-119	423.00
IUUC-Gga-041243	Gallus gallus	68.69	0.00e+00	847.00
IUUC-Gac-041340	Gasterosteus aculeatus	50.09	2.00e-115	409.00
IUUC-Gma-044387	Glycine max	50.00	5.00e-15	73.90
IUUC-Ggo-044953	Gorilla gorilla	96.78	0.00e+00	1446.00
IUUC-Hsa-046484	Homo sapiens	97.02	0.00e+00	1462.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	88.26	0.00e+00	1298.00
IUUC-Lch-050004	Latimeria chalumnae	59.78	0.00e+00	677.00
IUUC-Loc-051830	Lepisosteus oculatus	61.18	0.00e+00	786.00
IUUC-Laf-053975	Loxodonta africana	85.91	0.00e+00	1263.00
IUUC-Mcc-055302	Macaca mulatta	95.26	0.00e+00	1375.00
IUUC-Meu-056263	Macropus eugenii	75.74	0.00e+00	796.00
IUUC-Mtr-058744	Medicago truncatula	54.17	2.00e-13	68.60
IUUC-Mga-059706	Meleagris gallopavo	72.30	0.00e+00	1076.00
IUUC-Mmr-061372	Microcebus murinus	90.00	0.00e+00	1252.00
IUUC-Mdo-062651	Monodelphis domestica	66.10	0.00e+00	869.00
IUUC-Mmu-064339	Mus musculus	84.07	0.00e+00	1248.00
IUUC-Mac-065356	Musa acuminata	50.00	9.00e-13	67.80
IUUC-Mpu-066211	Mustela putorius furo	86.58	0.00e+00	1273.00
IUUC-Mlu-067058	Myotis lucifugus	87.81	0.00e+00	1238.00
IUUC-Nle-069886	Nomascus leucogenys	97.09	0.00e+00	1429.00
IUUC-Opr-070218	Ochotona princeps	81.77	0.00e+00	1091.00
IUUC-Ont-072483	Oreochromis niloticus	61.68	0.00e+00	778.00
IUUC-Oan-073718	Ornithorhynchus anatinus	71.64	0.00e+00	920.00
IUUC-Ocu-073847	Oryctolagus cuniculus	79.34	0.00e+00	1053.00
IUUC-Oba-075528	Oryza barthii	43.64	3.00e-12	66.20
IUUC-Obr-076184	Oryza brachyantha	53.33	2.00e-12	66.60
IUUC-Opu-083306	Oryza punctata	67.44	7.00e-13	67.00
IUUC-Ola-087358	Oryzias latipes	62.40	0.00e+00	765.00
IUUC-Oga-088362	Otolemur garnettii	88.00	0.00e+00	1321.00
IUUC-Oar-090197	Ovis aries	99.49	1.00e-96	346.00
IUUC-Ptr-091350	Pan troglodytes	96.90	0.00e+00	1460.00
IUUC-Pan-091700	Papio anubis	94.92	0.00e+00	1372.00
IUUC-Psi-093301	Pelodiscus sinensis	69.98	0.00e+00	1001.00
IUUC-Pfo-096917	Poecilia formosa	63.85	0.00e+00	770.00
IUUC-Pop-099640	Populus trichocarpa	57.14	1.00e-14	72.80
IUUC-Pca-101054	Procavia capensis	94.37	0.00e+00	986.00
IUUC-Ppe-101991	Prunus persica	54.17	3.00e-13	67.80
IUUC-Pva-102879	Pteropus vampyrus	88.89	0.00e+00	1329.00
IUUC-Pgr-103476	Puccinia graminis	41.27	3.00e-09	56.20
IUUC-Sha-106507	Sarcophilus harrisii	54.83	3.00e-168	585.00
IUUC-Sit-110656	Setaria italica	67.44	6.00e-13	67.00
IUUC-Stu-112500	Solanum tuberosum	62.79	6.00e-13	66.60
IUUC-Sar-113182	Sorex araneus	87.89	3.00e-111	396.00
IUUC-Sbi-114414	Sorghum bicolor	41.03	5.00e-13	67.00
IUUC-Ssc-115966	Sus scrofa	80.60	0.00e+00	1075.00
IUUC-Tgu-116864	Taeniopygia guttata	64.27	0.00e+00	699.00
IUUC-Tru-118502	Takifugu rubripes	61.29	0.00e+00	744.00
IUUC-Tsy-119210	Tarsius syrichta	88.76	0.00e+00	1278.00
IUUC-Tni-120344	Tetraodon nigroviridis	53.26	4.00e-125	441.00
IUUC-Tca-120966	Theobroma cacao	48.39	3.00e-13	69.30
IUUC-Tur-125977	Triticum urartu	50.00	2.00e-13	70.10
IUUC-Tbe-127735	Tupaia belangeri	88.58	8.00e-140	491.00
IUUC-Ttr-128714	Tursiops truncatus	75.98	0.00e+00	1009.00
IUUC-Vvi-131280	Vitis vinifera	31.50	2.00e-13	69.70
IUUC-Xtr-132280	Xenopus tropicalis	59.05	0.00e+00	701.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence