iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054136

UUCD1 version

UUC-LoA-00826

Ensembl Protein ID

ENSLAFP00000023696.1

UniProt Accession

G3U788; G3U788_LOXAF

Protein Name

Uncharacterized protein

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000025968.1	ENSLAFT00000031771.1	ENSLAFP00000023696.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	92.54	5.00e-108	387.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

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Nucleotide Sequence
(Fasta)

ATGGTCACCC ACAGCAAGTT TCCCGCCGCC GGGATGAGCC GCCCCCTGGA CACCAGCCTG 60
CGCCTCAAGA CCTTCAGCTC CAAGAGCGAG TACCAGCTCG TGGTGAACGC AGTGCGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

KEGG

lav:100670741

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	90.35	4.00e-105	373.00
IUUC-Apl-003607	Anas platyrhynchos	80.26	1.00e-94	338.00
IUUC-Aca-005063	Anolis carolinensis	80.00	5.00e-101	359.00
IUUC-Ath-006990	Arabidopsis thaliana	32.86	1.80e-02	35.00
IUUC-Ame-010859	Astyanax mexicanus	55.36	2.00e-67	248.00
IUUC-Bta-012817	Bos taurus	90.83	1.00e-107	381.00
IUUC-Bra-017963	Brassica rapa	31.43	2.40e-02	33.50
IUUC-Cja-019605	Callithrix jacchus	92.11	6.00e-110	389.00
IUUC-Cfa-021231	Canis familiaris	92.11	1.00e-106	379.00
IUUC-Cpo-022003	Cavia porcellus	94.30	6.00e-108	382.00
IUUC-Csa-023511	Chlorocebus sabaeus	92.11	4.00e-108	383.00
IUUC-Dre-028536	Danio rerio	57.02	3.00e-71	260.00
IUUC-Dno-029003	Dasypus novemcinctus	88.60	1.00e-106	378.00
IUUC-Eca-034205	Equus caballus	83.80	9.00e-68	248.00
IUUC-Fca-036317	Felis catus	89.82	6.00e-105	372.00
IUUC-Gmo-038777	Gadus morhua	63.89	6.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	81.14	2.00e-94	338.00
IUUC-Gac-041837	Gasterosteus aculeatus	54.74	4.00e-64	237.00
IUUC-Ggo-045620	Gorilla gorilla	92.11	4.00e-108	383.00
IUUC-Hsa-046909	Homo sapiens	92.11	4.00e-108	383.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	89.74	2.00e-109	388.00
IUUC-Lch-049510	Latimeria chalumnae	66.38	3.00e-83	300.00
IUUC-Loc-052863	Lepisosteus oculatus	61.37	8.00e-78	282.00
IUUC-Mcc-055383	Macaca mulatta	92.11	4.00e-108	383.00
IUUC-Meu-056153	Macropus eugenii	86.40	2.00e-108	384.00
IUUC-Mmr-061185	Microcebus murinus	90.79	3.00e-106	377.00
IUUC-Mdo-061819	Monodelphis domestica	86.84	7.00e-107	379.00
IUUC-Mmu-064231	Mus musculus	91.67	2.00e-112	397.00
IUUC-Mpu-066691	Mustela putorius furo	92.11	1.00e-106	379.00
IUUC-Mlu-067673	Myotis lucifugus	90.79	4.00e-112	396.00
IUUC-Ont-072406	Oreochromis niloticus	54.31	1.00e-67	248.00
IUUC-Oan-073249	Ornithorhynchus anatinus	74.56	3.00e-93	333.00
IUUC-Ocu-074935	Oryctolagus cuniculus	88.24	3.00e-31	125.00
IUUC-Ola-087373	Oryzias latipes	46.19	2.00e-47	181.00
IUUC-Oga-088041	Otolemur garnettii	91.67	3.00e-108	383.00
IUUC-Oar-089646	Ovis aries	89.08	1.00e-102	365.00
IUUC-Ptr-091502	Pan troglodytes	92.11	4.00e-108	383.00
IUUC-Pan-091934	Papio anubis	92.11	4.00e-108	383.00
IUUC-Pfo-096412	Poecilia formosa	41.81	1.00e-47	182.00
IUUC-Pab-098554	Pongo abelii	92.11	4.00e-108	383.00
IUUC-Rno-105874	Rattus norvegicus	91.23	3.00e-112	397.00
IUUC-Sha-107151	Sarcophilus harrisii	87.72	4.00e-109	386.00
IUUC-Ssc-115722	Sus scrofa	82.29	2.00e-64	237.00
IUUC-Tgu-117151	Taeniopygia guttata	80.70	9.00e-94	335.00
IUUC-Tru-118428	Takifugu rubripes	54.74	1.00e-67	248.00
IUUC-Tni-120590	Tetraodon nigroviridis	53.88	5.00e-66	243.00
IUUC-Ttr-129065	Tursiops truncatus	92.14	5.00e-108	383.00
IUUC-Xtr-132167	Xenopus tropicalis	64.91	1.00e-80	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence