iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107151

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01164736

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017840.1	ENSSHAT00000021209.1	ENSSHAP00000021039.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	87.28	7.00e-109	390.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MVTHSKFPAT GMNRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAACCC ACAGCAAGTT CCCCGCCACA GGGATGAACC GCCCCCTGGA CACCAGCCTG 60
CGCCTCAAGA CCTTCAGCTC CAAAAGCGAA TACCAGCTGG TGGTGAACGC TGTGCGCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

KEGG

shr:100934360

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	85.53	8.00e-104	369.00
IUUC-Apl-003607	Anas platyrhynchos	80.70	6.00e-96	342.00
IUUC-Aca-005063	Anolis carolinensis	77.54	9.00e-99	352.00
IUUC-Ath-006990	Arabidopsis thaliana	32.86	1.70e-02	35.00
IUUC-Ame-010859	Astyanax mexicanus	54.94	1.00e-66	245.00
IUUC-Bta-012817	Bos taurus	87.34	8.00e-108	382.00
IUUC-Cja-019605	Callithrix jacchus	88.16	7.00e-110	389.00
IUUC-Cfa-021231	Canis familiaris	85.96	7.00e-105	372.00
IUUC-Cpo-022003	Cavia porcellus	89.04	5.00e-106	376.00
IUUC-Csa-023511	Chlorocebus sabaeus	85.96	5.00e-108	383.00
IUUC-Dre-028536	Danio rerio	57.08	6.00e-70	256.00
IUUC-Dno-029003	Dasypus novemcinctus	85.09	3.00e-106	377.00
IUUC-Eca-034205	Equus caballus	80.45	9.00e-67	245.00
IUUC-Fca-036317	Felis catus	83.63	6.00e-105	372.00
IUUC-Gmo-038777	Gadus morhua	63.89	6.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	80.70	5.00e-94	336.00
IUUC-Gac-041837	Gasterosteus aculeatus	55.29	8.00e-64	236.00
IUUC-Ggo-045620	Gorilla gorilla	85.96	5.00e-108	383.00
IUUC-Hsa-046909	Homo sapiens	85.96	5.00e-108	383.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	85.04	5.00e-108	383.00
IUUC-Lch-049510	Latimeria chalumnae	64.66	2.00e-80	291.00
IUUC-Loc-052863	Lepisosteus oculatus	59.92	1.00e-75	275.00
IUUC-Laf-054136	Loxodonta africana	87.72	6.00e-108	382.00
IUUC-Mcc-055383	Macaca mulatta	85.96	5.00e-108	383.00
IUUC-Meu-056153	Macropus eugenii	96.49	2.00e-117	414.00
IUUC-Mmr-061185	Microcebus murinus	85.53	2.00e-104	370.00
IUUC-Mdo-061819	Monodelphis domestica	95.61	2.00e-116	410.00
IUUC-Mmu-064231	Mus musculus	86.84	5.00e-109	386.00
IUUC-Mpu-066691	Mustela putorius furo	85.96	7.00e-105	372.00
IUUC-Mlu-067673	Myotis lucifugus	84.65	1.00e-108	385.00
IUUC-Ont-072406	Oreochromis niloticus	52.59	1.00e-65	242.00
IUUC-Oan-073249	Ornithorhynchus anatinus	75.44	4.00e-93	333.00
IUUC-Ocu-074935	Oryctolagus cuniculus	83.82	9.00e-31	124.00
IUUC-Ola-087373	Oryzias latipes	45.93	4.00e-47	180.00
IUUC-Oga-088041	Otolemur garnettii	85.96	8.00e-107	379.00
IUUC-Oar-089646	Ovis aries	84.72	1.00e-100	358.00
IUUC-Ptr-091502	Pan troglodytes	85.96	5.00e-108	383.00
IUUC-Pan-091934	Papio anubis	85.96	5.00e-108	383.00
IUUC-Pfo-096412	Poecilia formosa	42.24	7.00e-47	179.00
IUUC-Pab-098554	Pongo abelii	85.96	5.00e-108	383.00
IUUC-Rno-105874	Rattus norvegicus	87.28	2.00e-109	388.00
IUUC-Ssc-115722	Sus scrofa	77.14	9.00e-64	235.00
IUUC-Tgu-117151	Taeniopygia guttata	80.26	3.00e-93	333.00
IUUC-Tru-118428	Takifugu rubripes	52.59	9.00e-66	242.00
IUUC-Tni-120590	Tetraodon nigroviridis	53.02	6.00e-65	239.00
IUUC-Ttr-129065	Tursiops truncatus	88.21	9.00e-108	382.00
IUUC-Xtr-132167	Xenopus tropicalis	64.91	1.00e-80	292.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence