iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002153

Ensembl Protein ID

ENSAMEP00000018459.1

UniProt Accession

G1MGH5; G1MGH5_AILME

Genbank Protein ID

ENSAMEP00000018459

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01112794

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000017472.1	ENSAMET00000019202.1	ENSAMEP00000018459.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	9.80e-08	32.0	5	45
ULD/UDP/UFD/UBX	2.80e-20	72.8	569	646
ULD/UDP/UBQ/UBQ_Other	6.60e-11	42.0	110	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 1    sededkleqlve.MGF.dreealqaLraannnleaAveyLl 39
           +++e++l+ +++ +G+ + +ea++ L+++n++l aA++ ++
   Q: 5    MDREMILADFQAcTGIeNIDEAITLLEQNNWDLVAAINGVI 45
           689**********************************9875 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           +++ ++l+iR+p+G++l+r+F +s++l+ +++fv+ ++++++d+F+L+s+fPrr++++ + +++l e +L+p+++l++e
   Q: 569  AEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVA-SKGFPWDEFKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLE 646
           56799******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+e+K+ +e +l ip   +++++kG      ed   L++++l+ ++ +++l
   Q: 110  NVDVVLEDSCTVGEIKQILENELQIP--VSKMLLKGWKTgdvEDSTVLKSLHLPKNNSLYVL 169
           5566678999****************..55899997776777***************99987 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MASNMDREMI LADFQACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG ILQSDYGGET 60
IPGPAFDPSH PAPAPAPSSS SAFRPVMPSR QIVERQPRML DFRVEYRDRN VDVVLEDSCT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTCCA ATATGGACCG GGAGATGATC CTGGCGGATT TTCAGGTGAA GTCTATGGCC 60
CCGTTCCTCT TCCACTTCCA GCCTCGTGGG TTCCCGGTGC CTGAAGGGTT GCCTCTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004127	Anas platyrhynchos	90.60	0.00e+00	1136.00
IUUC-Aca-005188	Anolis carolinensis	89.80	0.00e+00	1127.00
IUUC-Ame-010696	Astyanax mexicanus	77.73	0.00e+00	873.00
IUUC-Bta-012965	Bos taurus	97.08	0.00e+00	1231.00
IUUC-Cel-018420	Caenorhabditis elegans	29.12	1.00e-29	124.00
IUUC-Cja-019128	Callithrix jacchus	96.48	0.00e+00	1228.00
IUUC-Cfa-021201	Canis familiaris	97.29	0.00e+00	911.00
IUUC-Cpo-021475	Cavia porcellus	96.49	0.00e+00	906.00
IUUC-Csa-024076	Chlorocebus sabaeus	97.23	0.00e+00	1233.00
IUUC-Cho-025067	Choloepus hoffmanni	83.20	0.00e+00	1065.00
IUUC-Cin-025663	Ciona intestinalis	43.79	1.00e-68	253.00
IUUC-Csv-025894	Ciona savignyi	35.02	4.00e-70	258.00
IUUC-Dre-027508	Danio rerio	76.45	0.00e+00	940.00
IUUC-Dno-029336	Dasypus novemcinctus	96.15	0.00e+00	1209.00
IUUC-Dor-030218	Dipodomys ordii	89.68	0.00e+00	1108.00
IUUC-Dme-031581	Drosophila melanogaster	35.39	1.00e-87	317.00
IUUC-Ete-032860	Echinops telfairi	74.33	0.00e+00	675.00
IUUC-Eca-034321	Equus caballus	98.93	0.00e+00	1062.00
IUUC-Eeu-034844	Erinaceus europaeus	73.58	4.00e-146	511.00
IUUC-Fca-036575	Felis catus	99.73	0.00e+00	736.00
IUUC-Fal-037128	Ficedula albicollis	90.94	0.00e+00	1157.00
IUUC-Gmo-038694	Gadus morhua	74.27	0.00e+00	902.00
IUUC-Gga-040826	Gallus gallus	91.55	0.00e+00	1161.00
IUUC-Gac-042125	Gasterosteus aculeatus	75.38	0.00e+00	966.00
IUUC-Ggo-045254	Gorilla gorilla	97.08	0.00e+00	1234.00
IUUC-Hsa-046722	Homo sapiens	96.92	0.00e+00	1232.00
IUUC-Itr-048149	Ictidomys tridecemlineatus	98.28	5.00e-103	365.00
IUUC-Lch-050312	Latimeria chalumnae	80.58	0.00e+00	672.00
IUUC-Loc-051990	Lepisosteus oculatus	81.86	0.00e+00	966.00
IUUC-Laf-054375	Loxodonta africana	98.67	0.00e+00	731.00
IUUC-Mcc-054627	Macaca mulatta	96.70	0.00e+00	1201.00
IUUC-Meu-056611	Macropus eugenii	71.43	4.00e-131	461.00
IUUC-Mga-059400	Meleagris gallopavo	89.25	0.00e+00	1135.00
IUUC-Mvi-060242	Microbotryum violaceum	26.39	7.20e-02	31.60
IUUC-Mmr-060882	Microcebus murinus	97.07	0.00e+00	1198.00
IUUC-Mdo-061874	Monodelphis domestica	91.69	0.00e+00	1174.00
IUUC-Mmu-063444	Mus musculus	96.30	0.00e+00	1229.00
IUUC-Mpu-065713	Mustela putorius furo	99.05	0.00e+00	1194.00
IUUC-Mlu-068122	Myotis lucifugus	95.79	0.00e+00	1166.00
IUUC-Nle-069025	Nomascus leucogenys	96.62	0.00e+00	1222.00
IUUC-Opr-071089	Ochotona princeps	86.44	0.00e+00	1106.00
IUUC-Ont-072421	Oreochromis niloticus	75.00	0.00e+00	952.00
IUUC-Oan-073092	Ornithorhynchus anatinus	87.65	0.00e+00	855.00
IUUC-Ola-086497	Oryzias latipes	76.01	0.00e+00	963.00
IUUC-Oga-088854	Otolemur garnettii	96.30	0.00e+00	1221.00
IUUC-Oar-090120	Ovis aries	97.23	0.00e+00	1208.00
IUUC-Ptr-091554	Pan troglodytes	97.08	0.00e+00	1234.00
IUUC-Pan-091985	Papio anubis	96.77	0.00e+00	1204.00
IUUC-Psi-093548	Pelodiscus sinensis	90.88	0.00e+00	1092.00
IUUC-Pma-094123	Petromyzon marinus	52.45	3.00e-52	197.00
IUUC-Pfo-096729	Poecilia formosa	74.33	0.00e+00	952.00
IUUC-Pab-097810	Pongo abelii	97.23	0.00e+00	1236.00
IUUC-Pca-101079	Procavia capensis	89.56	0.00e+00	902.00
IUUC-Pva-102534	Pteropus vampyrus	88.31	0.00e+00	927.00
IUUC-Ptt-103866	Puccinia triticina	38.18	7.40e-01	28.90
IUUC-Rno-105127	Rattus norvegicus	95.92	0.00e+00	1112.00
IUUC-Sha-106667	Sarcophilus harrisii	93.47	0.00e+00	1033.00
IUUC-Ssl-108656	Sclerotinia sclerotiorum	23.88	2.50e-02	32.30
IUUC-Sar-113424	Sorex araneus	83.76	0.00e+00	658.00
IUUC-Ssc-115974	Sus scrofa	96.38	0.00e+00	1176.00
IUUC-Tgu-116495	Taeniopygia guttata	90.94	0.00e+00	1158.00
IUUC-Tru-118727	Takifugu rubripes	73.80	0.00e+00	931.00
IUUC-Tsy-118906	Tarsius syrichta	91.53	0.00e+00	1110.00
IUUC-Tni-119717	Tetraodon nigroviridis	75.92	0.00e+00	954.00
IUUC-Tbe-127849	Tupaia belangeri	82.66	0.00e+00	730.00
IUUC-Ttr-128660	Tursiops truncatus	92.79	0.00e+00	1162.00
IUUC-Vpa-130359	Vicugna pacos	97.01	0.00e+00	1204.00
IUUC-Xtr-132212	Xenopus tropicalis	87.10	0.00e+00	722.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence