iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-019128

Ensembl Protein ID

ENSCJAP00000040136.1

UniProt Accession

F7I2S1; F7I2S1_CALJA

Genbank Protein ID

JAB02100.1; JAB13980.1; JAB31018.1; JAB36697.1; JAB46309.1

Protein Name

FAS-associated factor 1

Genbank Nucleotide ID

ACFV01112726; GAMS01009156; GAMR01002914; GAMQ01005154; GAMP01006446

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000021555.2	ENSCJAT00000042393.2	ENSCJAP00000040134.2
ENSCJAG00000021555.2	ENSCJAT00000042392.2	ENSCJAP00000040133.2
ENSCJAG00000021555.2	ENSCJAT00000042395.1	ENSCJAP00000040136.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.90e-07	32.0	5	45
ULD/UDP/UFD/UBX	4.40e-19	69.8	573	650
ULD/UDP/UBQ/UBQ_Other	4.20e-10	40.3	114	173

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 1    sededkleqlve.MGF.dreealqaLraannnleaAveyLl 39
           +++e++l+ +++ +G+ + +ea++ L+++n++l aA++ ++
   Q: 5    MDREMILADFQAcTGIeNIDEAITLLEQNNWDLVAAINGVI 45
           689**********************************9875 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           +++ ++l+iR+p+G++l+r+F +s +l+ +++fv+ ++++++d+++L+s+fPrr++++ + +++l e +L+p+++l++e
   Q: 573  AEPVSKLRIRTPSGEFLERRFLASSKLQIVFDFVA-SKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLE 650
           56799******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+e+K+ +e +l ip   +++++kG      ed   L++++l+ ++ +++l
   Q: 114  NVDVVLEDSCTVGEIKQILENELQIP--VSKMLLKGWKTgdvEDSTVLKSLHLPKNNSLYVL 173
           5566678999****************..55899997776777***************99987 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MASNMDREMI LADFQACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG ILQSEYGSET 60
IPGPAFNPAS HPTPVSTSSS SSSSSAFRPV MPSRQIVERQ PRMLDFRVEY RDRNVDVVLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGCGGA GGCGGCGGCC AGGGAGGAAG CGGAGGAGGC GGAGGCGGCC GTGGCGTTCA 60
CCCGCCCGCT CGCTCTCTCG GTTTCCCCGC CCCCGCCGGC TTAACGCAGC TGAAGGGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

KEGG

cjc:100395232

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	96.32	0.00e+00	1219.00
IUUC-Apl-004127	Anas platyrhynchos	91.09	0.00e+00	1137.00
IUUC-Aca-005188	Anolis carolinensis	90.45	0.00e+00	1127.00
IUUC-Ame-010696	Astyanax mexicanus	77.45	0.00e+00	869.00
IUUC-Bta-012965	Bos taurus	96.48	0.00e+00	1221.00
IUUC-Cel-018420	Caenorhabditis elegans	29.12	1.00e-29	124.00
IUUC-Cfa-021201	Canis familiaris	96.67	0.00e+00	907.00
IUUC-Cpo-021475	Cavia porcellus	96.27	0.00e+00	906.00
IUUC-Csa-024076	Chlorocebus sabaeus	98.16	0.00e+00	1236.00
IUUC-Cho-025067	Choloepus hoffmanni	83.31	0.00e+00	1060.00
IUUC-Cin-025663	Ciona intestinalis	43.79	6.00e-69	254.00
IUUC-Csv-025894	Ciona savignyi	34.56	9.00e-71	260.00
IUUC-Dre-027508	Danio rerio	75.56	0.00e+00	944.00
IUUC-Dno-029336	Dasypus novemcinctus	95.87	0.00e+00	1209.00
IUUC-Dor-030218	Dipodomys ordii	89.13	0.00e+00	1096.00
IUUC-Dme-031581	Drosophila melanogaster	35.56	1.00e-87	317.00
IUUC-Ete-032860	Echinops telfairi	75.31	0.00e+00	677.00
IUUC-Eca-034321	Equus caballus	98.40	0.00e+00	1059.00
IUUC-Eeu-034844	Erinaceus europaeus	73.53	4.00e-144	504.00
IUUC-Fca-036575	Felis catus	98.67	0.00e+00	730.00
IUUC-Fal-037128	Ficedula albicollis	91.27	0.00e+00	1160.00
IUUC-Gmo-038694	Gadus morhua	73.66	0.00e+00	904.00
IUUC-Gga-040826	Gallus gallus	91.88	0.00e+00	1164.00
IUUC-Gac-042125	Gasterosteus aculeatus	75.23	0.00e+00	971.00
IUUC-Ggo-045254	Gorilla gorilla	98.01	0.00e+00	1238.00
IUUC-Hsa-046722	Homo sapiens	97.86	0.00e+00	1236.00
IUUC-Itr-048149	Ictidomys tridecemlineatus	98.28	3.00e-103	366.00
IUUC-Lch-050312	Latimeria chalumnae	81.58	0.00e+00	667.00
IUUC-Loc-051990	Lepisosteus oculatus	82.01	0.00e+00	969.00
IUUC-Laf-054375	Loxodonta africana	98.67	0.00e+00	732.00
IUUC-Mcc-054627	Macaca mulatta	97.97	0.00e+00	1207.00
IUUC-Meu-056611	Macropus eugenii	72.83	2.00e-131	462.00
IUUC-Mga-059400	Meleagris gallopavo	89.59	0.00e+00	1138.00
IUUC-Mvi-060242	Microbotryum violaceum	26.39	9.00e-02	31.20
IUUC-Mmr-060882	Microcebus murinus	96.32	0.00e+00	1194.00
IUUC-Mdo-061874	Monodelphis domestica	91.58	0.00e+00	1175.00
IUUC-Mmu-063444	Mus musculus	95.10	0.00e+00	1212.00
IUUC-Mpu-065713	Mustela putorius furo	95.77	0.00e+00	1181.00
IUUC-Mlu-068122	Myotis lucifugus	95.50	0.00e+00	1161.00
IUUC-Nle-069025	Nomascus leucogenys	97.55	0.00e+00	1227.00
IUUC-Opr-071089	Ochotona princeps	85.76	0.00e+00	1096.00
IUUC-Ont-072421	Oreochromis niloticus	74.70	0.00e+00	954.00
IUUC-Oan-073092	Ornithorhynchus anatinus	88.07	0.00e+00	853.00
IUUC-Ola-086497	Oryzias latipes	75.86	0.00e+00	968.00
IUUC-Oga-088854	Otolemur garnettii	96.02	0.00e+00	1213.00
IUUC-Oar-090120	Ovis aries	96.63	0.00e+00	1201.00
IUUC-Ptr-091554	Pan troglodytes	98.01	0.00e+00	1238.00
IUUC-Pan-091985	Papio anubis	98.01	0.00e+00	1213.00
IUUC-Psi-093548	Pelodiscus sinensis	91.38	0.00e+00	1092.00
IUUC-Pma-094123	Petromyzon marinus	52.45	6.00e-52	196.00
IUUC-Pfo-096729	Poecilia formosa	74.18	0.00e+00	953.00
IUUC-Pab-097810	Pongo abelii	98.16	0.00e+00	1241.00
IUUC-Pca-101079	Procavia capensis	89.56	0.00e+00	902.00
IUUC-Pva-102534	Pteropus vampyrus	87.45	0.00e+00	922.00
IUUC-Rno-105127	Rattus norvegicus	94.17	0.00e+00	1095.00
IUUC-Sha-106667	Sarcophilus harrisii	93.47	0.00e+00	1033.00
IUUC-Ssl-108656	Sclerotinia sclerotiorum	24.63	1.30e-02	33.10
IUUC-Sar-113424	Sorex araneus	82.83	0.00e+00	653.00
IUUC-Ssc-115974	Sus scrofa	96.55	0.00e+00	1170.00
IUUC-Tgu-116495	Taeniopygia guttata	91.27	0.00e+00	1162.00
IUUC-Tru-118727	Takifugu rubripes	73.20	0.00e+00	933.00
IUUC-Tsy-118906	Tarsius syrichta	91.73	0.00e+00	1106.00
IUUC-Tni-119717	Tetraodon nigroviridis	76.07	0.00e+00	958.00
IUUC-Tbe-127849	Tupaia belangeri	82.80	0.00e+00	729.00
IUUC-Ttr-128660	Tursiops truncatus	92.04	0.00e+00	1155.00
IUUC-Vpa-130359	Vicugna pacos	97.02	0.00e+00	1200.00
IUUC-Xtr-132212	Xenopus tropicalis	82.95	0.00e+00	721.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence