iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090120

Ensembl Protein ID

ENSOARP00000004605.1

UniProt Accession

W5P2F6; W5P2F6_SHEEP

Genbank Protein ID

ENSOARP00000004605

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01001452

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000004305.1	ENSOART00000004686.1	ENSOARP00000004605.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.10e-07	32.0	5	45
ULD/UDP/UFD/UBX	2.90e-20	72.8	570	647
ULD/UDP/UBQ/UBQ_Other	8.00e-11	41.9	111	170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 1    sededkleqlve.MGF.dreealqaLraannnleaAveyLl 39
           +++e++l+ +++ +G+ + +ea++ L+++n++l aA++ ++
   Q: 5    MDREMILADFQAcTGIeNIDEAITLLEQNNWDLVAAINGVI 45
           689**********************************9875 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           +++ ++l+iR+p+G++l+r+F +s++l+ +++fv+ ++++++d+F+L+s+fPrr++++ + +++l e +L+p+++l++e
   Q: 570  AEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVA-SKGFPWDEFKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLE 647
           56799******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+e+K+ +e +l ip   +++++kG      ed   L++++l+ ++ +++l
   Q: 111  NVDVVLEDSCTVGEIKQILENELQIP--VSKMLLKGWKTgdvEDSTVLKSLHLPKNNSLYVL 170
           5566678999****************..55899997776777***************99987 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MTSNMDREMI LADFQACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG ILQSDYGGET 60
ISGPAFDPAS HPAPAPAPSS SSAFRPVMPS RQIVERQPRM LDFRVEYRDR NVDVVLEDSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGTCCA ACATGGACCG GGAGATGATC CTGGCGGATT TTCAGGTGAA GTATTGGGCC 60
CGATTATCCT CCCATCTCCA ACCTCGTGGC TTTCCAGTGC CCACAGGGTG GCCTCTTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

KEGG

oas:101108967

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	98.15	0.00e+00	1219.00
IUUC-Apl-004127	Anas platyrhynchos	90.75	0.00e+00	1131.00
IUUC-Aca-005188	Anolis carolinensis	89.32	0.00e+00	1130.00
IUUC-Ame-010696	Astyanax mexicanus	77.88	0.00e+00	870.00
IUUC-Bta-012965	Bos taurus	99.23	0.00e+00	1237.00
IUUC-Cel-018420	Caenorhabditis elegans	29.12	1.00e-29	124.00
IUUC-Cja-019128	Callithrix jacchus	96.63	0.00e+00	1222.00
IUUC-Cfa-021201	Canis familiaris	97.08	0.00e+00	906.00
IUUC-Cpo-021475	Cavia porcellus	96.49	0.00e+00	903.00
IUUC-Csa-024076	Chlorocebus sabaeus	97.85	0.00e+00	1226.00
IUUC-Cho-025067	Choloepus hoffmanni	83.54	0.00e+00	1054.00
IUUC-Cin-025663	Ciona intestinalis	43.79	1.00e-68	253.00
IUUC-Csv-025894	Ciona savignyi	34.76	4.00e-70	258.00
IUUC-Dre-027508	Danio rerio	76.15	0.00e+00	943.00
IUUC-Dno-029336	Dasypus novemcinctus	96.77	0.00e+00	1201.00
IUUC-Dor-030218	Dipodomys ordii	90.00	0.00e+00	1098.00
IUUC-Dme-031581	Drosophila melanogaster	32.58	2.00e-92	333.00
IUUC-Ete-032860	Echinops telfairi	75.98	0.00e+00	672.00
IUUC-Eca-034321	Equus caballus	98.93	0.00e+00	1059.00
IUUC-Eeu-034844	Erinaceus europaeus	76.28	2.00e-146	512.00
IUUC-Fca-036575	Felis catus	99.73	0.00e+00	737.00
IUUC-Fal-037128	Ficedula albicollis	90.94	0.00e+00	1151.00
IUUC-Gmo-038694	Gadus morhua	75.04	0.00e+00	911.00
IUUC-Gga-040826	Gallus gallus	91.09	0.00e+00	1156.00
IUUC-Gac-042125	Gasterosteus aculeatus	75.69	0.00e+00	973.00
IUUC-Ggo-045254	Gorilla gorilla	98.00	0.00e+00	1229.00
IUUC-Hsa-046722	Homo sapiens	97.85	0.00e+00	1228.00
IUUC-Itr-048149	Ictidomys tridecemlineatus	98.28	6.00e-103	365.00
IUUC-Lch-050312	Latimeria chalumnae	81.53	0.00e+00	672.00
IUUC-Loc-051990	Lepisosteus oculatus	81.83	0.00e+00	967.00
IUUC-Laf-054375	Loxodonta africana	98.67	0.00e+00	732.00
IUUC-Mcc-054627	Macaca mulatta	98.12	0.00e+00	1204.00
IUUC-Meu-056611	Macropus eugenii	72.59	1.00e-132	466.00
IUUC-Mga-059400	Meleagris gallopavo	88.94	0.00e+00	1132.00
IUUC-Mvi-060242	Microbotryum violaceum	26.39	6.80e-02	31.60
IUUC-Mmr-060882	Microcebus murinus	97.38	0.00e+00	1188.00
IUUC-Mdo-061874	Monodelphis domestica	91.85	0.00e+00	1174.00
IUUC-Mmu-063444	Mus musculus	96.62	0.00e+00	1214.00
IUUC-Mpu-065713	Mustela putorius furo	97.01	0.00e+00	1185.00
IUUC-Mlu-068122	Myotis lucifugus	97.66	0.00e+00	1174.00
IUUC-Nle-069025	Nomascus leucogenys	97.54	0.00e+00	1219.00
IUUC-Opr-071089	Ochotona princeps	86.31	0.00e+00	1092.00
IUUC-Ont-072421	Oreochromis niloticus	75.45	0.00e+00	958.00
IUUC-Oan-073092	Ornithorhynchus anatinus	89.51	0.00e+00	853.00
IUUC-Ola-086497	Oryzias latipes	76.61	0.00e+00	969.00
IUUC-Oga-088854	Otolemur garnettii	95.69	0.00e+00	1216.00
IUUC-Ptr-091554	Pan troglodytes	98.00	0.00e+00	1229.00
IUUC-Pan-091985	Papio anubis	98.31	0.00e+00	1206.00
IUUC-Psi-093548	Pelodiscus sinensis	91.51	0.00e+00	1094.00
IUUC-Pma-094123	Petromyzon marinus	52.45	7.00e-52	196.00
IUUC-Pfo-096729	Poecilia formosa	75.22	0.00e+00	959.00
IUUC-Pab-097810	Pongo abelii	98.15	0.00e+00	1232.00
IUUC-Pca-101079	Procavia capensis	89.56	0.00e+00	898.00
IUUC-Pva-102534	Pteropus vampyrus	90.35	0.00e+00	927.00
IUUC-Rno-105127	Rattus norvegicus	96.42	0.00e+00	1099.00
IUUC-Sha-106667	Sarcophilus harrisii	93.10	0.00e+00	1029.00
IUUC-Ssl-108656	Sclerotinia sclerotiorum	23.88	2.50e-02	32.30
IUUC-Sar-113424	Sorex araneus	83.76	0.00e+00	659.00
IUUC-Ssc-115974	Sus scrofa	98.43	0.00e+00	1172.00
IUUC-Tgu-116495	Taeniopygia guttata	90.94	0.00e+00	1152.00
IUUC-Tru-118727	Takifugu rubripes	74.25	0.00e+00	935.00
IUUC-Tsy-118906	Tarsius syrichta	92.62	0.00e+00	1103.00
IUUC-Tni-119717	Tetraodon nigroviridis	76.69	0.00e+00	958.00
IUUC-Tbe-127849	Tupaia belangeri	83.76	0.00e+00	719.00
IUUC-Ttr-128660	Tursiops truncatus	94.48	0.00e+00	1160.00
IUUC-Vpa-130359	Vicugna pacos	98.74	0.00e+00	1202.00
IUUC-Xtr-132212	Xenopus tropicalis	86.87	0.00e+00	722.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence