iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068539

Ensembl Protein ID

CADNFIAP00007459

UniProt Accession

A1DFP5; VPS27_NEOFI

Genbank Protein ID

EAW18202.1

Protein Name

Vacuolar protein sorting-associated protein 27

Genbank Nucleotide ID

DS027696

Gene Name

NFIA_081460; vps27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00007626	CADNFIAT00007626	CADNFIAP00007459

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UIM	32.96	8.00e-40	162.00	IUUC-Bta-012506
UBD/Alpha-Helix/UIM	39.46	1.00e-38	158.00	IUUC-Dme-031952
UBD/Alpha-Helix/DUIM	33.33	9.00e-40	163.00	IUUC-Hsa-046009
UBD/Alpha-Helix/VHS	33.33	9.00e-40	163.00	IUUC-Hsa-046009
UBD/Alpha-Helix/UIM	32.59	2.00e-39	162.00	IUUC-Mmu-063952
UBD/Alpha-Helix/VHS	32.48	2.00e-39	161.00	IUUC-Rno-105125
UBD/Alpha-Helix/UIM	35.18	1.00e-73	272.00	IUUC-Sce-106192
UBD/Alpha-Helix/UIM	43.83	3.00e-98	354.00	IUUC-Spo-108220
UBD/Alpha-Helix/GAT	30.99	7.00e-14	75.50	IUUC-Ots-000031

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Neosartorya fischeri

Functional Description
(View)

Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.

Protein Sequence
(Fasta)

MAGWFSSTSL LDEQVERATS SSLEDIALNL EISDLIRSKS VQPKEAMRSL KRRLENRNPN 60
VQIATLKLTD TCVKNGGSHF LAEIASREFM DNLVSLLTTE GAPLNTDVKE KMLELIQDWA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGTT GGTTTTCCTC TACTTCTCTT CTCGACGAGC AGGTTGAGCG TGCGACATCA 60
TCCTCGCTGT ATGTTTTCTT TGATTTGAAT TTTCCCAGTG GTTAAAGTTG CCCAGGCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF02809--UIM
PF00790--VHS

SMART

SM00064--FYVE
SM00726--UIM
SM00288--VHS

Gene Ontology

GO:0010008--C:endosome membrane
GO:0046872--F:metal ion binding
GO:0006886--P:intracellular protein transport

KEGG

nfi:NFIA_081460

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	36.92	1.00e-40	159.00
IUUC-Atr-003138	Amborella trichopoda	33.90	8.00e-13	67.00
IUUC-Apl-003662	Anas platyrhynchos	33.64	1.00e-35	143.00
IUUC-Aca-004940	Anolis carolinensis	35.00	2.00e-39	155.00
IUUC-Aly-005656	Arabidopsis lyrata	34.46	1.00e-16	80.10
IUUC-Ath-007359	Arabidopsis thaliana	33.99	2.00e-17	82.80
IUUC-Ago-007931	Ashbya gossypii	35.91	1.00e-69	256.00
IUUC-Acl-008274	Aspergillus clavatus	78.90	0.00e+00	1059.00
IUUC-Afl-008521	Aspergillus flavus	69.96	0.00e+00	947.00
IUUC-Afu-008774	Aspergillus fumigatus	95.06	0.00e+00	1265.00
IUUC-Ani-009445	Aspergillus nidulans	67.52	0.00e+00	913.00
IUUC-Ang-009863	Aspergillus niger	70.26	0.00e+00	939.00
IUUC-Ate-010444	Aspergillus terreus	82.94	0.00e+00	801.00
IUUC-Ame-011111	Astyanax mexicanus	36.82	1.00e-39	156.00
IUUC-Bgr-012087	Blumeria graminis	52.20	1.00e-167	581.00
IUUC-Bta-012506	Bos taurus	35.91	7.00e-41	160.00
IUUC-Bci-013782	Botrytis cinerea	65.31	0.00e+00	673.00
IUUC-Bol-015832	Brassica oleracea	34.90	6.00e-17	80.90
IUUC-Bra-017805	Brassica rapa	34.90	3.00e-17	81.60
IUUC-Cel-018493	Caenorhabditis elegans	38.79	7.00e-40	157.00
IUUC-Cja-019998	Callithrix jacchus	35.27	3.00e-35	142.00
IUUC-Cfa-020615	Canis familiaris	35.91	2.00e-40	159.00
IUUC-Cpo-022019	Cavia porcellus	35.91	6.00e-41	160.00
IUUC-Cre-022771	Chlamydomonas reinhardtii	31.03	4.00e-12	63.20
IUUC-Csa-023596	Chlorocebus sabaeus	36.36	5.00e-41	160.00
IUUC-Cin-025488	Ciona intestinalis	36.12	5.00e-41	160.00
IUUC-Csv-025802	Ciona savignyi	36.24	5.00e-36	143.00
IUUC-Cne-026847	Cryptococcus neoformans	37.39	3.00e-77	281.00
IUUC-Dre-028353	Danio rerio	38.07	7.00e-41	160.00
IUUC-Dno-029005	Dasypus novemcinctus	35.00	5.00e-40	157.00
IUUC-Dor-030280	Dipodomys ordii	35.45	5.00e-40	157.00
IUUC-Dse-031238	Dothistroma septosporum	62.87	4.00e-169	586.00
IUUC-Dme-031952	Drosophila melanogaster	39.46	4.00e-40	157.00
IUUC-Ete-032235	Echinops telfairi	35.65	7.00e-39	154.00
IUUC-Eca-033873	Equus caballus	36.57	7.00e-41	160.00
IUUC-Eeu-034652	Erinaceus europaeus	34.50	3.00e-25	108.00
IUUC-Fca-036563	Felis catus	35.91	7.00e-41	160.00
IUUC-Fal-036649	Ficedula albicollis	35.57	9.00e-38	150.00
IUUC-Fox-037962	Fusarium oxysporum	64.71	7.00e-173	598.00
IUUC-Fso-038396	Fusarium solani	66.27	0.00e+00	637.00
IUUC-Gmo-039510	Gadus morhua	36.57	1.00e-40	159.00
IUUC-Ggr-039938	Gaeumannomyces graminis	59.88	3.00e-164	570.00
IUUC-Gga-040201	Gallus gallus	35.19	2.00e-39	155.00
IUUC-Gac-041459	Gasterosteus aculeatus	37.50	9.00e-41	160.00
IUUC-Gma-043377	Glycine max	32.20	1.00e-14	73.60
IUUC-Ggo-044573	Gorilla gorilla	36.36	2.00e-41	162.00
IUUC-Hsa-046009	Homo sapiens	36.36	3.00e-41	161.00
IUUC-Hvu-047351	Hordeum vulgare	33.57	2.00e-16	79.30
IUUC-Itr-049065	Ictidomys tridecemlineatus	35.91	7.00e-41	160.00
IUUC-Kpa-049327	Komagataella pastoris	35.83	7.00e-77	280.00
IUUC-Lch-050236	Latimeria chalumnae	32.72	9.00e-26	108.00
IUUC-Loc-051850	Lepisosteus oculatus	36.53	6.00e-38	150.00
IUUC-Lma-053252	Leptosphaeria maculans	61.60	2.00e-167	581.00
IUUC-Laf-053346	Loxodonta africana	35.62	3.00e-40	158.00
IUUC-Mcc-055789	Macaca mulatta	36.36	3.00e-41	162.00
IUUC-Meu-056329	Macropus eugenii	31.02	4.00e-27	114.00
IUUC-Mor-057205	Magnaporthe oryzae	59.18	3.00e-176	610.00
IUUC-Mpo-057295	Magnaporthe poae	60.04	1.00e-172	598.00
IUUC-Mtr-057784	Medicago truncatula	34.44	4.00e-17	81.60
IUUC-Mla-058849	Melampsora laricipopulina	32.89	1.00e-65	242.00
IUUC-Mga-059361	Meleagris gallopavo	36.41	1.00e-38	153.00
IUUC-Mvi-060561	Microbotryum violaceum	37.17	2.00e-69	255.00
IUUC-Mmr-061122	Microcebus murinus	35.91	2.00e-40	159.00
IUUC-Mdo-062171	Monodelphis domestica	35.56	1.00e-40	159.00
IUUC-Mmu-063952	Mus musculus	35.91	6.00e-41	160.00
IUUC-Mpu-065852	Mustela putorius furo	35.91	1.00e-40	159.00
IUUC-Mlu-067475	Myotis lucifugus	37.96	2.00e-18	84.70
IUUC-Ncr-068726	Neurospora crassa	63.35	2.00e-177	614.00
IUUC-Nle-070148	Nomascus leucogenys	32.73	1.00e-31	129.00
IUUC-Opr-070833	Ochotona princeps	39.68	3.00e-25	108.00
IUUC-Ont-071261	Oreochromis niloticus	37.56	4.00e-38	151.00
IUUC-Oan-073103	Ornithorhynchus anatinus	36.96	1.00e-17	82.80
IUUC-Ocu-073922	Oryctolagus cuniculus	37.14	2.00e-18	85.10
IUUC-Oba-075578	Oryza barthii	36.28	7.00e-16	77.40
IUUC-Ogl-077232	Oryza glaberrima	36.28	7.00e-16	77.40
IUUC-Ogu-078454	Oryza glumaepatula	36.28	8.00e-16	77.40
IUUC-Oin-080097	Oryza indica	36.28	7.00e-16	77.40
IUUC-Ome-081795	Oryza meridionalis	36.28	5.00e-16	77.80
IUUC-Oni-082061	Oryza nivara	36.28	7.00e-16	77.40
IUUC-Oru-084443	Oryza rufipogon	36.28	7.00e-16	77.40
IUUC-Osa-085724	Oryza sativa	36.28	7.00e-16	77.40
IUUC-Ola-087570	Oryzias latipes	35.00	2.00e-33	136.00
IUUC-Oga-089087	Otolemur garnettii	35.68	1.00e-35	143.00
IUUC-Oar-089534	Ovis aries	36.36	4.00e-41	161.00
IUUC-Ptr-091654	Pan troglodytes	30.45	1.00e-28	119.00
IUUC-Pan-092652	Papio anubis	36.36	3.00e-41	161.00
IUUC-Psi-093744	Pelodiscus sinensis	40.29	2.00e-20	92.00
IUUC-Pma-094514	Petromyzon marinus	37.50	7.00e-19	86.30
IUUC-Pno-095125	Phaeosphaeria nodorum	60.45	1.00e-164	571.00
IUUC-Pfo-096757	Poecilia formosa	37.50	9.00e-38	150.00
IUUC-Pab-097788	Pongo abelii	36.36	4.00e-41	160.00
IUUC-Pop-099695	Populus trichocarpa	31.97	8.00e-15	73.60
IUUC-Pca-100145	Procavia capensis	28.44	1.00e-25	109.00
IUUC-Ppe-101305	Prunus persica	34.75	2.00e-15	75.90
IUUC-Pva-102965	Pteropus vampyrus	35.45	3.00e-40	158.00
IUUC-Pgr-103609	Puccinia graminis	47.57	5.00e-56	210.00
IUUC-Ptt-103865	Puccinia triticina	41.83	2.00e-55	209.00
IUUC-Pte-104095	Pyrenophora teres	63.80	3.00e-168	583.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	62.33	1.00e-169	588.00
IUUC-Rno-105125	Rattus norvegicus	35.91	6.00e-41	160.00
IUUC-Sce-106192	Saccharomyces cerevisiae	35.18	1.00e-75	275.00
IUUC-Sha-107066	Sarcophilus harrisii	35.91	2.00e-40	159.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	40.60	9.00e-87	313.00
IUUC-Spo-108220	Schizosaccharomyces pombe	44.26	4.00e-101	360.00
IUUC-Ssl-108413	Sclerotinia sclerotiorum	71.60	6.00e-66	241.00
IUUC-Smo-109609	Selaginella moellendorffii	31.25	6.00e-15	73.20
IUUC-Sit-109878	Setaria italica	24.00	2.00e-15	75.90
IUUC-Sly-111100	Solanum lycopersicum	35.17	1.00e-17	83.20
IUUC-Stu-112464	Solanum tuberosum	40.35	3.00e-10	59.30
IUUC-Sar-113393	Sorex araneus	33.85	1.00e-29	122.00
IUUC-Sre-114986	Sporisorium reilianum	54.95	4.00e-69	254.00
IUUC-Ssc-115258	Sus scrofa	46.03	1.00e-14	73.60
IUUC-Tgu-117505	Taeniopygia guttata	35.81	2.00e-39	155.00
IUUC-Tru-118494	Takifugu rubripes	36.36	3.00e-40	158.00
IUUC-Tni-120174	Tetraodon nigroviridis	37.27	8.00e-42	163.00
IUUC-Tca-121260	Theobroma cacao	32.31	7.00e-16	77.00
IUUC-Tre-122191	Trichoderma reesei	63.55	0.00e+00	632.00
IUUC-Tvi-122318	Trichoderma virens	60.00	0.00e+00	636.00
IUUC-Tme-126914	Tuber melanosporum	60.13	5.00e-157	546.00
IUUC-Tbe-127731	Tupaia belangeri	35.19	8.00e-13	66.60
IUUC-Ttr-129095	Tursiops truncatus	36.36	2.00e-41	162.00
IUUC-Uma-129475	Ustilago maydis	37.88	6.00e-82	297.00
IUUC-Vpa-130520	Vicugna pacos	34.65	5.00e-15	73.60
IUUC-Vvi-131199	Vitis vinifera	32.86	4.00e-17	81.30
IUUC-Xtr-131900	Xenopus tropicalis	36.07	1.00e-40	159.00
IUUC-Xma-133124	Xiphophorus maculatus	37.27	2.00e-38	152.00
IUUC-Yli-134682	Yarrowia lipolytica	44.69	8.00e-105	372.00
IUUC-Zma-134959	Zea mays	36.28	6.00e-15	74.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence