iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Cel-018332

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

UBiquitin Conjugating enzyme

Genbank Nucleotide ID

BX284603

Gene Name

ubc-18; CELE_R01H2.6; R01H2.6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
WBGene00006713	R01H2.6	R01H2.6

Annotation

mRNA Expression
GEO
DNA & RNA Element
microRNA
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	20157562; 19553937

Classification

Family	E-value	Score	Start	End
E2/UBC	4.10e-40	137.0	6	141

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvl 102
           Rl+kel +l++  ++ +     +e++l +w vl++ p++ pY++g+Fk+ i+fp dYPfkPPkv f+tki+hPnv+e+Gk Cl i+ ++e+W+pa++ e+v+
   Q: 6    RLQKELGDLKNCGVKAYENVECEETNLLKWTVLLI-PDKEPYNKGAFKVGITFPVDYPFKPPKVAFETKIYHPNVDEEGKFCLPIV-TAENWKPATKTEQVM 105
           9****************99999999*********9.**************************************************.5************** PP
   S: 103  lsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +++ sl++ep+p++p ++++ae+++k+++++ k+++
   Q: 106  MALLSLINEPEPSHPIRADVAEEFQKDHKKFMKTAE 141
           *******************************99986 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSATRRLQKE LGDLKNCGVK AYENVECEET NLLKWTVLLI PDKEPYNKGA FKVGITFPVD 60
YPFKPPKVAF ETKIYHPNVD EEGKFCLPIV TAENWKPATK TEQVMMALLS LINEPEPSHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTAACCCA ACTAGAGCGT TTATATCAAC ATGTCAGCGA CACGGCGTCT TCAGAAGGTG 60
AGAAAATCAT GTTTATTGTA CAATTCACAA TTCAAATGTT CAGGAACTCG GTGATCTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0008340--P:determination of adult lifespan
GO:0048557--P:embryonic digestive tract morphogenesis
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0016567--P:protein ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

cel:CELE_R01H2.6

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001446	Ailuropoda melanoleuca	63.96	2.00e-34	136.00
IUUC-Apl-003318	Anas platyrhynchos	58.33	1.00e-44	170.00
IUUC-Aca-005234	Anolis carolinensis	57.89	2.00e-45	172.00
IUUC-Ame-011452	Astyanax mexicanus	56.29	3.00e-45	172.00
IUUC-Bta-012693	Bos taurus	58.33	1.00e-44	170.00
IUUC-Cja-019062	Callithrix jacchus	59.21	1.00e-48	183.00
IUUC-Cfa-020027	Canis familiaris	59.21	1.00e-48	183.00
IUUC-Cpo-022341	Cavia porcellus	59.21	1.00e-48	183.00
IUUC-Csa-023794	Chlorocebus sabaeus	46.67	2.00e-37	146.00
IUUC-Cho-024821	Choloepus hoffmanni	49.31	2.00e-38	150.00
IUUC-Cin-025130	Ciona intestinalis	60.53	5.00e-43	165.00
IUUC-Csv-026183	Ciona savignyi	60.26	3.00e-45	172.00
IUUC-Dre-027710	Danio rerio	59.21	3.00e-49	186.00
IUUC-Dno-029371	Dasypus novemcinctus	63.48	3.00e-36	141.00
IUUC-Dor-031017	Dipodomys ordii	56.58	3.00e-43	166.00
IUUC-Dme-031814	Drosophila melanogaster	59.87	9.00e-59	217.00
IUUC-Ete-032754	Echinops telfairi	59.21	1.00e-48	183.00
IUUC-Eca-034056	Equus caballus	57.24	6.00e-47	178.00
IUUC-Eeu-034942	Erinaceus europaeus	59.21	1.00e-48	184.00
IUUC-Fca-036173	Felis catus	59.21	1.00e-48	183.00
IUUC-Fal-036820	Ficedula albicollis	58.74	9.00e-45	171.00
IUUC-Gmo-038480	Gadus morhua	56.64	7.00e-44	167.00
IUUC-Gga-041039	Gallus gallus	59.21	1.00e-48	183.00
IUUC-Gac-041571	Gasterosteus aculeatus	56.95	2.00e-42	163.00
IUUC-Ggo-044482	Gorilla gorilla	59.03	5.00e-45	171.00
IUUC-Hsa-046287	Homo sapiens	59.21	1.00e-48	183.00
IUUC-Itr-049057	Ictidomys tridecemlineatus	59.70	2.00e-41	159.00
IUUC-Lch-049699	Latimeria chalumnae	65.79	6.00e-36	141.00
IUUC-Loc-052000	Lepisosteus oculatus	57.14	5.00e-47	178.00
IUUC-Laf-053833	Loxodonta africana	58.62	4.00e-45	172.00
IUUC-Mcc-054978	Macaca mulatta	58.55	2.00e-58	216.00
IUUC-Meu-056738	Macropus eugenii	59.22	2.00e-29	118.00
IUUC-Mga-060134	Meleagris gallopavo	58.00	1.00e-44	170.00
IUUC-Mmr-061002	Microcebus murinus	58.62	1.00e-44	171.00
IUUC-Mdo-062043	Monodelphis domestica	48.65	2.00e-43	166.00
IUUC-Mmu-063615	Mus musculus	59.21	1.00e-48	183.00
IUUC-Mpu-066122	Mustela putorius furo	45.95	3.00e-36	142.00
IUUC-Mlu-067987	Myotis lucifugus	57.89	2.00e-57	213.00
IUUC-Nle-069967	Nomascus leucogenys	58.55	2.00e-58	216.00
IUUC-Opr-070315	Ochotona princeps	59.21	1.00e-48	183.00
IUUC-Ont-072036	Oreochromis niloticus	59.87	2.00e-49	186.00
IUUC-Oan-073297	Ornithorhynchus anatinus	54.55	3.00e-30	122.00
IUUC-Ocu-074565	Oryctolagus cuniculus	57.14	5.00e-46	175.00
IUUC-Ola-086994	Oryzias latipes	56.16	9.00e-53	197.00
IUUC-Oga-088085	Otolemur garnettii	56.58	6.00e-55	204.00
IUUC-Oar-089520	Ovis aries	58.62	2.00e-45	172.00
IUUC-Ptr-090890	Pan troglodytes	58.55	1.00e-57	213.00
IUUC-Pan-092445	Papio anubis	59.03	5.00e-45	171.00
IUUC-Psi-093989	Pelodiscus sinensis	61.81	5.00e-48	181.00
IUUC-Pma-094445	Petromyzon marinus	58.27	2.00e-41	159.00
IUUC-Pfo-096258	Poecilia formosa	59.87	7.00e-49	185.00
IUUC-Pab-097654	Pongo abelii	59.21	1.00e-48	183.00
IUUC-Pca-100712	Procavia capensis	47.37	2.00e-31	127.00
IUUC-Pva-103113	Pteropus vampyrus	58.74	1.00e-44	170.00
IUUC-Pgr-103630	Puccinia graminis	42.28	3.00e-33	132.00
IUUC-Ptt-103816	Puccinia triticina	42.18	3.00e-32	129.00
IUUC-Rno-104863	Rattus norvegicus	42.76	5.00e-35	138.00
IUUC-Sha-106823	Sarcophilus harrisii	58.99	1.00e-43	167.00
IUUC-Sar-113240	Sorex araneus	58.74	1.00e-44	170.00
IUUC-Ssc-115442	Sus scrofa	59.21	1.00e-48	183.00
IUUC-Tgu-117352	Taeniopygia guttata	58.33	1.00e-44	170.00
IUUC-Tru-117653	Takifugu rubripes	60.53	8.00e-50	187.00
IUUC-Tsy-119345	Tarsius syrichta	63.96	3.00e-34	136.00
IUUC-Tni-119709	Tetraodon nigroviridis	60.53	8.00e-50	187.00
IUUC-Tbe-127451	Tupaia belangeri	57.24	2.00e-55	206.00
IUUC-Ttr-128840	Tursiops truncatus	59.21	1.00e-48	183.00
IUUC-Xtr-132650	Xenopus tropicalis	58.55	1.00e-47	180.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence