iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062043

UUCD1 version

UUC-MoD-01039

Ensembl Protein ID

ENSMODP00000039021.1

UniProt Accession

K7DZS0; K7DZS0_MONDO

Protein Name

Uncharacterized protein

Gene Name

UBE2L3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000017665.3	ENSMODT00000042130.1	ENSMODP00000039021.1
ENSMODG00000017665.3	ENSMODT00000022411.2	ENSMODP00000022024.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.60e-39	133.2	6	101

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl+kel+e++k  +++++  +vde++l +w+ li+ p++ pY++g+F++ei+fp +YPfkPPk++f tki+hPn++e+G+vCl ++ ++
   Q: 6    RLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVI-SA 92
           9**********************************.**************************************************.5* PP
   S: 90   ekWspalsv 98
           e+W+pa++ 
   Q: 93   ENWKPATKT 101
           *****9986 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE 60
YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQERDHHQR VSWGRRSLEF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTAGAGCCC AGGCTCGGCC CCGCCCCTCA GCGCTCGCGC GCGGCAGGAA GTGCAGGGGC 60
TCGAGCCGCC CGGCGGCCGC GATGCATTGT GGGACAGCAG CAGCACCAGA CCCAAGATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0003713--F:transcription coactivator activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0044770--P:cell cycle phase transition
GO:0008283--P:cell proliferation
GO:0071385--P:cellular response to glucocorticoid stimulus
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001446	Ailuropoda melanoleuca	77.40	9.00e-48	181.00
IUUC-Apl-003318	Anas platyrhynchos	78.07	3.00e-68	249.00
IUUC-Aca-005234	Anolis carolinensis	80.66	7.00e-69	252.00
IUUC-Ame-011452	Astyanax mexicanus	76.80	1.00e-63	234.00
IUUC-Bta-012693	Bos taurus	81.01	9.00e-68	248.00
IUUC-Cel-018332	Caenorhabditis elegans	48.65	3.00e-53	200.00
IUUC-Cja-019062	Callithrix jacchus	82.35	4.00e-73	266.00
IUUC-Cfa-020027	Canis familiaris	82.35	4.00e-73	266.00
IUUC-Cpo-022341	Cavia porcellus	82.35	4.00e-73	266.00
IUUC-Csa-023794	Chlorocebus sabaeus	44.81	4.00e-40	156.00
IUUC-Cho-024916	Choloepus hoffmanni	93.14	1.00e-42	164.00
IUUC-Cin-025130	Ciona intestinalis	55.08	4.00e-42	163.00
IUUC-Csv-026183	Ciona savignyi	53.80	3.00e-42	163.00
IUUC-Dre-027710	Danio rerio	78.07	3.00e-68	250.00
IUUC-Dno-029371	Dasypus novemcinctus	78.00	7.00e-50	188.00
IUUC-Dor-031017	Dipodomys ordii	78.07	3.00e-66	243.00
IUUC-Dme-031814	Drosophila melanogaster	60.96	1.00e-63	234.00
IUUC-Ete-032754	Echinops telfairi	82.35	4.00e-73	266.00
IUUC-Eca-034056	Equus caballus	79.68	7.00e-71	258.00
IUUC-Eeu-034942	Erinaceus europaeus	81.28	3.00e-72	263.00
IUUC-Fca-036173	Felis catus	82.35	4.00e-73	266.00
IUUC-Fal-036820	Ficedula albicollis	81.46	5.00e-68	249.00
IUUC-Gmo-038480	Gadus morhua	74.16	6.00e-60	222.00
IUUC-Gga-041039	Gallus gallus	82.35	4.00e-73	266.00
IUUC-Gac-041571	Gasterosteus aculeatus	63.59	2.00e-51	194.00
IUUC-Ggo-044482	Gorilla gorilla	81.67	7.00e-69	252.00
IUUC-Hsa-046287	Homo sapiens	82.35	4.00e-73	266.00
IUUC-Itr-049057	Ictidomys tridecemlineatus	80.47	5.00e-62	229.00
IUUC-Lch-049699	Latimeria chalumnae	63.76	1.00e-38	151.00
IUUC-Loc-052000	Lepisosteus oculatus	77.54	1.00e-67	248.00
IUUC-Laf-053833	Loxodonta africana	81.01	2.00e-67	247.00
IUUC-Mcc-055015	Macaca mulatta	81.28	1.00e-71	261.00
IUUC-Meu-056738	Macropus eugenii	100.00	9.00e-48	181.00
IUUC-Mga-060134	Meleagris gallopavo	80.00	2.00e-68	250.00
IUUC-Mmr-060627	Microcebus murinus	79.14	4.00e-79	286.00
IUUC-Mmu-063615	Mus musculus	82.35	4.00e-73	266.00
IUUC-Mpu-066122	Mustela putorius furo	39.23	5.00e-36	142.00
IUUC-Mlu-067987	Myotis lucifugus	80.75	1.00e-82	298.00
IUUC-Nle-069967	Nomascus leucogenys	80.21	3.00e-82	296.00
IUUC-Opr-070315	Ochotona princeps	82.35	4.00e-73	266.00
IUUC-Ont-072036	Oreochromis niloticus	76.47	3.00e-66	243.00
IUUC-Oan-073297	Ornithorhynchus anatinus	57.00	1.00e-33	134.00
IUUC-Ocu-074565	Oryctolagus cuniculus	79.37	6.00e-69	252.00
IUUC-Ola-086994	Oryzias latipes	67.91	3.00e-68	249.00
IUUC-Oga-088085	Otolemur garnettii	77.54	8.00e-79	285.00
IUUC-Oar-089520	Ovis aries	81.01	8.00e-68	248.00
IUUC-Ptr-090890	Pan troglodytes	81.82	2.00e-83	300.00
IUUC-Pan-092445	Papio anubis	81.67	7.00e-69	252.00
IUUC-Psi-093376	Pelodiscus sinensis	78.92	7.00e-68	249.00
IUUC-Pma-094445	Petromyzon marinus	64.53	1.00e-49	188.00
IUUC-Pfo-096258	Poecilia formosa	76.47	6.00e-66	243.00
IUUC-Pab-097654	Pongo abelii	82.35	4.00e-73	266.00
IUUC-Pca-100712	Procavia capensis	100.00	2.00e-47	181.00
IUUC-Pva-103113	Pteropus vampyrus	81.46	1.00e-67	248.00
IUUC-Rno-104863	Rattus norvegicus	41.62	7.00e-36	142.00
IUUC-Sha-106823	Sarcophilus harrisii	81.03	3.00e-65	240.00
IUUC-Sar-113240	Sorex araneus	81.46	1.00e-67	248.00
IUUC-Ssc-115442	Sus scrofa	82.35	4.00e-73	266.00
IUUC-Tgu-117352	Taeniopygia guttata	81.01	9.00e-68	248.00
IUUC-Tru-117653	Takifugu rubripes	76.47	1.00e-66	244.00
IUUC-Tsy-119345	Tarsius syrichta	65.24	4.00e-49	186.00
IUUC-Tni-119709	Tetraodon nigroviridis	76.47	1.00e-66	244.00
IUUC-Tbe-127451	Tupaia belangeri	77.54	2.00e-78	284.00
IUUC-Ttr-128840	Tursiops truncatus	82.35	4.00e-73	266.00
IUUC-Vpa-130649	Vicugna pacos	53.54	2.00e-30	123.00
IUUC-Xtr-132650	Xenopus tropicalis	80.21	6.00e-71	259.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence