iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067250

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02004898

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001168.2	ENSMLUT00000001172.2	ENSMLUP00000001072.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-38	129.0	11	43
E3 activity/RING/U-box	1.20e-25	89.4	403	475
UBD/Beta-Prp	3.40e-56	190.7	3	190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+afs+ ll+++s D+ti++++l++++
   Q: 11   HGDDVNCCAFSSSLLATCSLDKTIRLYSLSDFT 43
           9*********548***************98876 PP

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           e+p+ef+CpI+ elM+dPv++++G++y+++++e w++++++t+P+t+  l++  l+Pn tl+  i++w+e+++
   Q: 403  EIPDEFICPITRELMQDPVIASDGYSYEKEAMENWISKKKRTSPMTNLVLSSAVLTPNRTLKMAINRWLETHQ 475
           69********************************************************************997 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcv..htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           kl+++l +h + v+++ fs++  +l+t+s D+ti++++ls+++ +  + lk h++ v ++ fspsg+ l+s s d t  +w++++gq l
   Q: 3    KLIHTLADHGDDVNCCAFSSS--LLATCSLDKTIRLYSLSDFTELahSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTQNGQTL 89
           789999999999999999999..999999999999999996665511558899999999999999999999999999999999999999 PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
             + ++  + v++ +++pd+ +lvsG++D+tv lW+ ++ kl r  +   ++s    +f+++g+ +v+gs  g++++wd +   c+++ 
   Q: 90   AVMVQPSGSPVRVCRFSPDSTCLVSGAADGTVILWNAQSYKLHRCGSV-EDGSLVACAFSPDGNLFVTGSSCGDLTVWDDKMR-CLHSE 176
           988999999999999999999999999999999999988887666665.9999999999999999999999999999999655.99999 PP
   S: 219  nghtdnvksvrfsp 232
           ++h+  +++ +fs+
   Q: 177  KAHDLGMTCCDFSS 190
           99999999999985 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MVKLIHTLAD HGDDVNCCAF SSSLLATCSL DKTIRLYSLS DFTELAHSPL KFHTYAVHCC 60
CFSPSGHILA SCSTDGTTVL WNTQNGQTLA VMVQPSGSPV RVCRFSPDST CLVSGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGAAAC TAATTCACAC ATTAGCTGAT CATGGCGATG ATGTCAACTG TTGTGCCTTC 60
TCCTCTTCCC TCTTGGCTAC TTGCTCCTTG GACAAAACAA TTCGCCTCTA CTCCCTGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	91.18	0.00e+00	905.00
IUUC-Apl-003529	Anas platyrhynchos	74.58	0.00e+00	751.00
IUUC-Aca-004257	Anolis carolinensis	68.17	0.00e+00	681.00
IUUC-Ame-011357	Astyanax mexicanus	52.31	1.00e-115	409.00
IUUC-Bta-013032	Bos taurus	88.26	0.00e+00	875.00
IUUC-Cja-018743	Callithrix jacchus	90.34	0.00e+00	897.00
IUUC-Cfa-021197	Canis familiaris	89.92	0.00e+00	897.00
IUUC-Cpo-022279	Cavia porcellus	87.82	0.00e+00	876.00
IUUC-Csa-023954	Chlorocebus sabaeus	91.39	0.00e+00	905.00
IUUC-Cho-025083	Choloepus hoffmanni	71.96	1.00e-154	538.00
IUUC-Cin-025786	Ciona intestinalis	33.87	1.00e-76	280.00
IUUC-Dre-028087	Danio rerio	56.17	3.00e-139	488.00
IUUC-Dno-028919	Dasypus novemcinctus	90.55	0.00e+00	899.00
IUUC-Dor-031112	Dipodomys ordii	86.13	0.00e+00	861.00
IUUC-Ete-032405	Echinops telfairi	86.88	0.00e+00	625.00
IUUC-Eca-033254	Equus caballus	89.71	0.00e+00	888.00
IUUC-Eeu-034545	Erinaceus europaeus	84.24	0.00e+00	817.00
IUUC-Fca-035482	Felis catus	92.23	0.00e+00	910.00
IUUC-Fal-036976	Ficedula albicollis	60.49	3.00e-160	558.00
IUUC-Gmo-039213	Gadus morhua	53.99	7.00e-135	473.00
IUUC-Gga-040561	Gallus gallus	73.58	0.00e+00	736.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.35	1.00e-138	486.00
IUUC-Ggo-045503	Gorilla gorilla	91.60	0.00e+00	909.00
IUUC-Hsa-045910	Homo sapiens	91.60	0.00e+00	910.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	88.59	0.00e+00	697.00
IUUC-Loc-052307	Lepisosteus oculatus	58.33	6.00e-164	570.00
IUUC-Laf-053587	Loxodonta africana	90.13	0.00e+00	894.00
IUUC-Mcc-055679	Macaca mulatta	91.39	0.00e+00	908.00
IUUC-Meu-055962	Macropus eugenii	69.75	0.00e+00	640.00
IUUC-Mga-059652	Meleagris gallopavo	72.54	0.00e+00	729.00
IUUC-Mmr-060943	Microcebus murinus	88.08	0.00e+00	868.00
IUUC-Mdo-062592	Monodelphis domestica	81.21	0.00e+00	811.00
IUUC-Mmu-063577	Mus musculus	78.78	0.00e+00	783.00
IUUC-Mpu-066422	Mustela putorius furo	89.71	0.00e+00	889.00
IUUC-Nle-069517	Nomascus leucogenys	91.18	0.00e+00	905.00
IUUC-Opr-070776	Ochotona princeps	88.24	0.00e+00	867.00
IUUC-Ont-071821	Oreochromis niloticus	57.53	2.00e-149	521.00
IUUC-Oan-073706	Ornithorhynchus anatinus	81.89	0.00e+00	818.00
IUUC-Ocu-074766	Oryctolagus cuniculus	81.25	0.00e+00	787.00
IUUC-Ola-086531	Oryzias latipes	57.05	3.00e-143	501.00
IUUC-Oga-088388	Otolemur garnettii	89.08	0.00e+00	885.00
IUUC-Oar-089748	Ovis aries	88.89	0.00e+00	875.00
IUUC-Ptr-090616	Pan troglodytes	91.33	0.00e+00	900.00
IUUC-Pan-091769	Papio anubis	90.70	0.00e+00	647.00
IUUC-Psi-093334	Pelodiscus sinensis	77.10	0.00e+00	724.00
IUUC-Pma-094383	Petromyzon marinus	47.36	6.00e-131	460.00
IUUC-Pfo-096801	Poecilia formosa	55.32	7.00e-143	500.00
IUUC-Pab-098139	Pongo abelii	90.72	0.00e+00	735.00
IUUC-Pca-100523	Procavia capensis	75.21	0.00e+00	726.00
IUUC-Pva-102286	Pteropus vampyrus	90.76	0.00e+00	868.00
IUUC-Rno-104831	Rattus norvegicus	80.67	0.00e+00	803.00
IUUC-Sha-107499	Sarcophilus harrisii	82.56	0.00e+00	823.00
IUUC-Sar-113389	Sorex araneus	86.34	0.00e+00	837.00
IUUC-Tgu-116769	Taeniopygia guttata	71.85	0.00e+00	713.00
IUUC-Tru-118774	Takifugu rubripes	53.91	7.00e-139	487.00
IUUC-Tsy-119595	Tarsius syrichta	78.40	5.00e-180	623.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.36	3.00e-143	501.00
IUUC-Tbe-127938	Tupaia belangeri	79.34	3.00e-141	494.00
IUUC-Ttr-128193	Tursiops truncatus	91.04	0.00e+00	764.00
IUUC-Vpa-130275	Vicugna pacos	91.18	0.00e+00	898.00
IUUC-Xtr-131982	Xenopus tropicalis	60.63	4.00e-168	584.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence