iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118774

UUCD1 version

UUC-TaR-00952

Ensembl Protein ID

ENSTRUP00000044012.1

UniProt Accession

H2V478; H2V478_TAKRU

Protein Name

Uncharacterized protein

Gene Name

wdsub1; LOC101073156

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000017181.1	ENSTRUT00000044157.1	ENSTRUP00000044009.1
ENSTRUG00000017181.1	ENSTRUT00000044158.1	ENSTRUP00000044010.1
ENSTRUG00000017181.1	ENSTRUT00000044159.1	ENSTRUP00000044011.1
ENSTRUG00000017181.1	ENSTRUT00000044160.1	ENSTRUP00000044012.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-32	110.4	52	88
E3 activity/RING/U-box	1.00e-24	87.6	416	483
UBD/Beta-Prp	1.90e-52	179.6	5	218

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH  +v+c++f ++  +l+s+s D t+ +W+++tg+ 
   Q: 52   GHGYGVHCCCFsTCgQFLASCSTDATVLIWSMDTGHI 88
           8999*******855799****************9986 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
           +p+eflCpI+ elMrdPv++++G++y+r++I+ w+ ++++++P+t+ pl  + l+Pn++lr  i++w 
   Q: 416  IPDEFLCPITRELMRDPVIAADGYSYEREAIASWIHTKNRSSPMTNLPLLTTLLTPNHSLRMAISRWK 483
           8******************************************************************6 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           i+tl++h+++v    +f  +++l+at s d+t+++++ ++ +   ++ lsgh  +v +++fs  g++l+++s+D+t+ +w+++tg +  
   Q: 5    ICTLQDHRDDVNW-CAF--SGQLFATCSGDKTLRIYNSHDFSErpFSPLSGHGYGVHCCCFSTCGQFLASCSTDATVLIWSMDTGHIEA 90
           79*******9887.688..9*******************976689******************************************** PP
   S: 89   tlk.ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           +l+    + v+ +++s ++ +lvsG +d ti +wd +++q  + t +g d++v   +++p ++++v+Gs+ + +rlW+l +++l  +  
   Q: 91   VLEhPGRSPVRICAISSDSAHLVSGASDGTIALWDFPSKQLRR-TGAGGDSTVVACSFSPCSQVFVTGSTYGDLRLWNLDMKQLEAEKN 178
           999334678********99***********************9.****************99*************************98 PP
   S: 177  gghtdsvyslsfdsng........kelvsgsldgtvklwdl 209
             h+  v++ +f++          ++l+s+++d+ +k+w +
   Q: 179  A-HDLGVTCCTFSPIIlsggqvvqFQLASCGQDSHLKIWAI 218
           7.*********9987788889999***************87 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MMSVICTLQD HRDDVNWCAF SGQLFATCSG DKTLRIYNSH DFSERPFSPL SGHGYGVHCC 60
CFSTCGQFLA SCSTDATVLI WSMDTGHIEA VLEHPGRSPV RICAISSDSA HLVSGASDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGTCTG TGATTTGCAC TTTACAAGAC CATCGAGACG ATGTCAACTG GTGCGCCTTC 60
TCGGGCCAAC TGTTCGCCAC ATGTTCTGGA GACAAAACTC TTAGGATATA TAACTCGCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	53.91	4.00e-143	501.00
IUUC-Apl-003529	Anas platyrhynchos	53.50	6.00e-140	490.00
IUUC-Aca-004257	Anolis carolinensis	52.21	5.00e-138	484.00
IUUC-Ame-011357	Astyanax mexicanus	56.35	7.00e-142	496.00
IUUC-Bta-013032	Bos taurus	54.53	3.00e-144	504.00
IUUC-Cja-018743	Callithrix jacchus	54.30	1.00e-142	499.00
IUUC-Cfa-021197	Canis familiaris	53.91	5.00e-143	500.00
IUUC-Cpo-022279	Cavia porcellus	53.91	3.00e-143	501.00
IUUC-Csa-023954	Chlorocebus sabaeus	54.73	1.00e-145	509.00
IUUC-Cin-025786	Ciona intestinalis	37.55	1.00e-83	303.00
IUUC-Dre-028087	Danio rerio	67.15	0.00e+00	637.00
IUUC-Dno-028919	Dasypus novemcinctus	54.94	3.00e-145	508.00
IUUC-Dor-031112	Dipodomys ordii	54.53	2.00e-144	505.00
IUUC-Ete-032405	Echinops telfairi	52.84	1.00e-96	345.00
IUUC-Eca-033254	Equus caballus	53.20	1.00e-143	503.00
IUUC-Eeu-034545	Erinaceus europaeus	54.00	2.00e-138	485.00
IUUC-Fca-035482	Felis catus	54.12	1.00e-142	499.00
IUUC-Gmo-039213	Gadus morhua	67.42	0.00e+00	629.00
IUUC-Gga-040561	Gallus gallus	53.28	5.00e-138	484.00
IUUC-Gac-041471	Gasterosteus aculeatus	81.03	0.00e+00	726.00
IUUC-Ggo-045503	Gorilla gorilla	53.91	8.00e-143	500.00
IUUC-Hsa-045910	Homo sapiens	53.91	1.00e-142	499.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	50.13	2.00e-106	379.00
IUUC-Loc-052307	Lepisosteus oculatus	64.48	0.00e+00	645.00
IUUC-Laf-053587	Loxodonta africana	54.73	1.00e-144	506.00
IUUC-Mcc-055679	Macaca mulatta	54.53	2.00e-144	505.00
IUUC-Mga-059652	Meleagris gallopavo	53.69	1.00e-139	489.00
IUUC-Mmr-060943	Microcebus murinus	53.69	5.00e-136	477.00
IUUC-Mdo-062592	Monodelphis domestica	54.10	4.00e-142	497.00
IUUC-Mmu-063577	Mus musculus	55.67	2.00e-148	518.00
IUUC-Mpu-066422	Mustela putorius furo	53.70	8.00e-143	500.00
IUUC-Mlu-067250	Myotis lucifugus	53.91	3.00e-141	494.00
IUUC-Nle-069517	Nomascus leucogenys	53.70	2.00e-142	498.00
IUUC-Opr-070776	Ochotona princeps	55.35	1.00e-146	513.00
IUUC-Ont-071821	Oreochromis niloticus	78.03	0.00e+00	744.00
IUUC-Oan-073706	Ornithorhynchus anatinus	53.29	2.00e-140	491.00
IUUC-Ocu-074766	Oryctolagus cuniculus	49.59	5.00e-126	444.00
IUUC-Ola-086531	Oryzias latipes	75.83	0.00e+00	717.00
IUUC-Oga-088388	Otolemur garnettii	53.70	3.00e-141	494.00
IUUC-Oar-089748	Ovis aries	55.35	2.00e-146	511.00
IUUC-Ptr-090616	Pan troglodytes	53.62	5.00e-141	494.00
IUUC-Pan-091769	Papio anubis	53.54	3.00e-96	345.00
IUUC-Pfo-096801	Poecilia formosa	72.12	0.00e+00	685.00
IUUC-Pab-098139	Pongo abelii	53.15	2.00e-111	395.00
IUUC-Pca-100523	Procavia capensis	50.00	1.00e-87	317.00
IUUC-Pva-102286	Pteropus vampyrus	54.53	4.00e-139	488.00
IUUC-Rno-104831	Rattus norvegicus	54.53	1.00e-145	509.00
IUUC-Sha-107499	Sarcophilus harrisii	53.70	3.00e-140	491.00
IUUC-Sar-113389	Sorex araneus	52.47	4.00e-137	481.00
IUUC-Tgu-116769	Taeniopygia guttata	52.88	9.00e-139	486.00
IUUC-Tni-119850	Tetraodon nigroviridis	81.80	0.00e+00	786.00
IUUC-Tbe-127938	Tupaia belangeri	49.38	1.00e-83	302.00
IUUC-Ttr-128193	Tursiops truncatus	53.18	1.00e-120	426.00
IUUC-Vpa-130275	Vicugna pacos	54.32	1.00e-141	496.00
IUUC-Xtr-131982	Xenopus tropicalis	50.00	2.00e-127	449.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence