iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000197694.14	ENST00000372731.8	ENSP00000361816.4
ENSG00000197694.14	ENST00000630804.2	ENSP00000486308.1
ENSG00000197694.14	ENST00000627441.2	ENSP00000486547.1
ENSG00000197694.14	ENST00000372739.5	ENSP00000361824.3
ENSG00000197694.14	ENST00000358161.9	ENSP00000350882.6
ENSG00000197694.14	ENST00000630866.1	ENSP00000487444.1
ENSG00000197694.14	ENST00000635806.1	ENSP00000489647.1
ENSG00000197694.14	ENST00000637820.1	ENSP00000490179.1
ENSG00000197694.14	ENST00000637903.1	ENSP00000490332.1
ENSG00000197694.14	ENST00000637032.1	ENSP00000490109.1
ENSG00000197694.14	ENST00000630981.1	ENSP00000486605.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	circBase	circRNADb	CircNet
miRTarBase	microRNA	TRANSFAC	miRWalk
RepTar	SomamiR	miRcode	RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
ClinVar	OMIM
Post-translational Modifications (PTMs)
PHOSIDA	BioGRID	mUbiSiDa
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.60e-10	40.7	969	1025

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ke+v +lydy+ ++  e t+kkGd+++++  ++++++W+k   e + ++G++P+ +v+kl+
   Q: 969  KELVLALYDYQEKSPREVTMKKGDILTLL--NSTNKDWWKV--EVNDRQGFVPAAYVKKLD 1025
           68899************************..8999****88..9**************996 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MDPSGVKVLE TAEDIQERRQ QVLDRYHRFK ELSTLRRQKL EDSYRFQFFQ RDAEELEKWI 60
QEKLQIASDE NYKDPTNLQG KLQKHQAFEA EVQANSGAIV KLDETGNLMI SEGHFASETI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATAAAAGAG GCGGGGCGCG CGCGTCGCCG CCACTACCCG CTGCGGAGTG AACGGTGTGG 60
AGCGGAGGCC GCGGAGGCTC CTCGGTCCTT CAGCACCCCT CGGCCCGACG CACCCACGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR014837--EF-hand_Ca_insen
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR013315--Spectrin_alpha_SH3
IPR002017--Spectrin_repeat

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50002--SH3

Pfam

PF13499--EF-hand_7
PF08726--EFhand_Ca_insen
PF00018--SH3_1
PF00435--Spectrin

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00054--EFh
SM00326--SH3
SM00150--SPEC

Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0015630--C:microtubule cytoskeleton
GO:0005509--F:calcium ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001430	Ailuropoda melanoleuca	97.16	0.00e+00	4801.00
IUUC-Apl-003692	Anas platyrhynchos	96.12	0.00e+00	4711.00
IUUC-Ame-010974	Astyanax mexicanus	90.88	0.00e+00	4511.00
IUUC-Bta-013123	Bos taurus	98.08	0.00e+00	4835.00
IUUC-Cja-019004	Callithrix jacchus	98.48	0.00e+00	4850.00
IUUC-Cfa-021120	Canis familiaris	97.64	0.00e+00	4823.00
IUUC-Cpo-022439	Cavia porcellus	96.38	0.00e+00	4644.00
IUUC-Csa-024191	Chlorocebus sabaeus	98.96	0.00e+00	4874.00
IUUC-Cho-024438	Choloepus hoffmanni	97.97	0.00e+00	2137.00
IUUC-Dre-028311	Danio rerio	88.47	0.00e+00	4457.00
IUUC-Dno-029578	Dasypus novemcinctus	98.12	0.00e+00	4843.00
IUUC-Dor-030109	Dipodomys ordii	98.15	0.00e+00	1183.00
IUUC-Dme-032108	Drosophila melanogaster	63.16	0.00e+00	3112.00
IUUC-Fca-036305	Felis catus	97.28	0.00e+00	4806.00
IUUC-Fal-036784	Ficedula albicollis	96.88	0.00e+00	4865.00
IUUC-Gmo-039575	Gadus morhua	88.41	0.00e+00	4368.00
IUUC-Gga-041118	Gallus gallus	95.96	0.00e+00	4758.00
IUUC-Gac-042549	Gasterosteus aculeatus	89.05	0.00e+00	4405.00
IUUC-Ggo-044946	Gorilla gorilla	99.04	0.00e+00	4877.00
IUUC-Lch-050567	Latimeria chalumnae	92.01	0.00e+00	4556.00
IUUC-Loc-052651	Lepisosteus oculatus	90.89	0.00e+00	4558.00
IUUC-Laf-053912	Loxodonta africana	98.04	0.00e+00	4856.00
IUUC-Mcc-054610	Macaca mulatta	99.80	0.00e+00	4936.00
IUUC-Meu-055913	Macropus eugenii	86.09	0.00e+00	1709.00
IUUC-Mga-059315	Meleagris gallopavo	96.00	0.00e+00	4779.00
IUUC-Mmr-061183	Microcebus murinus	99.24	0.00e+00	4909.00
IUUC-Mdo-062180	Monodelphis domestica	96.31	0.00e+00	4364.00
IUUC-Mmu-063687	Mus musculus	98.40	0.00e+00	4918.00
IUUC-Mpu-066425	Mustela putorius furo	97.28	0.00e+00	4808.00
IUUC-Mlu-067943	Myotis lucifugus	98.29	0.00e+00	4900.00
IUUC-Nle-069271	Nomascus leucogenys	99.05	0.00e+00	2419.00
IUUC-Opr-070237	Ochotona princeps	94.68	0.00e+00	4665.00
IUUC-Ont-072393	Oreochromis niloticus	89.05	0.00e+00	4425.00
IUUC-Oan-073113	Ornithorhynchus anatinus	96.04	0.00e+00	4727.00
IUUC-Ocu-074516	Oryctolagus cuniculus	97.40	0.00e+00	4855.00
IUUC-Ola-086839	Oryzias latipes	88.82	0.00e+00	4398.00
IUUC-Oga-089094	Otolemur garnettii	86.90	0.00e+00	4218.00
IUUC-Oar-089374	Ovis aries	98.89	0.00e+00	4393.00
IUUC-Ptr-090495	Pan troglodytes	99.00	0.00e+00	4873.00
IUUC-Pan-091959	Papio anubis	98.96	0.00e+00	4873.00
IUUC-Pab-097592	Pongo abelii	99.80	0.00e+00	4984.00
IUUC-Pca-100304	Procavia capensis	94.77	0.00e+00	2825.00
IUUC-Pva-102161	Pteropus vampyrus	97.41	0.00e+00	4374.00
IUUC-Rno-105394	Rattus norvegicus	98.60	0.00e+00	4883.00
IUUC-Sha-107395	Sarcophilus harrisii	97.36	0.00e+00	4806.00
IUUC-Ssc-116146	Sus scrofa	96.72	0.00e+00	4764.00
IUUC-Tgu-117103	Taeniopygia guttata	94.60	0.00e+00	4717.00
IUUC-Tru-118183	Takifugu rubripes	88.28	0.00e+00	3886.00
IUUC-Tsy-118789	Tarsius syrichta	83.04	0.00e+00	1174.00
IUUC-Tni-120816	Tetraodon nigroviridis	87.45	0.00e+00	4348.00
IUUC-Ttr-128853	Tursiops truncatus	92.96	0.00e+00	4458.00
IUUC-Vpa-130628	Vicugna pacos	97.33	0.00e+00	2844.00
IUUC-Xtr-132872	Xenopus tropicalis	90.56	0.00e+00	4454.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence