iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000197948.10	ENST00000435817.6	ENSP00000399259.2
ENSG00000197948.10	ENST00000522126.5	ENSP00000427796.1
ENSG00000197948.10	ENST00000522783.5	ENSP00000428677.1
ENSG00000197948.10	ENST00000518499.1	ENSP00000430448.1
ENSG00000197948.10	ENST00000519800.1	ENSP00000428776.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circBase	circRNADb
CircNet	miRTarBase	microRNA	TRANSFAC
TargetScan	RepTar	miRcode	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha	InWeb_IM
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	UniProt
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.80e-19	69.5	474	524

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFv 59
            v + y+a  +deLt+++G+ ++vi +e    +W+k+ ++ +g  G++Pe + 
   Q: 474  HVVFRYQAGREDELTITEGEWLEVI-EEGDADEWVKA-RNQHGEVGFVPERYL 524
           588**********************.7777789****.5***********996 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MQPPPRKVKP AQEVKLRFLE QLSILQTWQQ READLLEDIR SYSKQRAAIE REYGQALQKL 60
AGPFLKREGH RSGEMDSRGR TVFGAWRCLL DATVAGGQTR LQASDRYRDL AGGTGRSAKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTTCCTCC AGTTCCGGAG TCCAGTGGCT GACCGCCTTG CTGGAGCGGA GATGCAGCCG 60
CCGCCCCGAA AAGTGAGCTT GGCCCTGAAT GGGGACTCCT GGCGGGCTGG GGGAACGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0031594--C:neuromuscular junction
GO:0055037--C:recycling endosome
GO:0007274--P:neuromuscular synaptic transmission
GO:0030833--P:regulation of actin filament polymerization

KEGG

hsa:89848

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001547	Ailuropoda melanoleuca	91.19	0.00e+00	932.00
IUUC-Apl-003401	Anas platyrhynchos	44.14	4.00e-117	415.00
IUUC-Aca-004495	Anolis carolinensis	51.33	9.00e-172	597.00
IUUC-Bta-012414	Bos taurus	91.55	0.00e+00	928.00
IUUC-Cja-019001	Callithrix jacchus	94.50	0.00e+00	1092.00
IUUC-Cfa-020261	Canis familiaris	90.90	0.00e+00	1008.00
IUUC-Cpo-021303	Cavia porcellus	90.95	0.00e+00	1016.00
IUUC-Csa-024168	Chlorocebus sabaeus	96.96	0.00e+00	1063.00
IUUC-Dno-029012	Dasypus novemcinctus	84.02	0.00e+00	842.00
IUUC-Dor-030539	Dipodomys ordii	84.37	0.00e+00	909.00
IUUC-Ete-032615	Echinops telfairi	77.59	0.00e+00	801.00
IUUC-Eca-034431	Equus caballus	91.19	0.00e+00	852.00
IUUC-Eeu-035222	Erinaceus europaeus	76.37	5.00e-110	392.00
IUUC-Fca-036274	Felis catus	91.73	0.00e+00	967.00
IUUC-Gga-040200	Gallus gallus	46.23	2.00e-131	462.00
IUUC-Ggo-044698	Gorilla gorilla	98.94	0.00e+00	1126.00
IUUC-Itr-048848	Ictidomys tridecemlineatus	90.72	0.00e+00	1052.00
IUUC-Laf-053614	Loxodonta africana	89.34	0.00e+00	967.00
IUUC-Mcc-055801	Macaca mulatta	96.11	0.00e+00	1074.00
IUUC-Meu-055969	Macropus eugenii	74.71	0.00e+00	760.00
IUUC-Mga-059428	Meleagris gallopavo	47.65	3.00e-143	502.00
IUUC-Mvi-060384	Microbotryum violaceum	33.68	1.00e-06	48.50
IUUC-Mmr-060884	Microcebus murinus	94.22	0.00e+00	1004.00
IUUC-Mdo-062232	Monodelphis domestica	79.55	0.00e+00	858.00
IUUC-Mmu-063768	Mus musculus	90.88	0.00e+00	1011.00
IUUC-Mpu-066271	Mustela putorius furo	91.20	0.00e+00	974.00
IUUC-Mlu-067436	Myotis lucifugus	75.61	0.00e+00	785.00
IUUC-Nle-069391	Nomascus leucogenys	97.12	0.00e+00	1071.00
IUUC-Opr-070480	Ochotona princeps	79.19	0.00e+00	881.00
IUUC-Ont-072392	Oreochromis niloticus	43.85	3.00e-130	459.00
IUUC-Oan-073048	Ornithorhynchus anatinus	52.61	7.00e-116	410.00
IUUC-Ocu-074813	Oryctolagus cuniculus	91.55	0.00e+00	1010.00
IUUC-Ola-087476	Oryzias latipes	45.72	4.00e-124	438.00
IUUC-Oga-088857	Otolemur garnettii	92.47	0.00e+00	1012.00
IUUC-Oar-090308	Ovis aries	90.70	0.00e+00	916.00
IUUC-Ptr-091590	Pan troglodytes	99.26	0.00e+00	866.00
IUUC-Pan-091724	Papio anubis	96.38	0.00e+00	1096.00
IUUC-Pfo-096841	Poecilia formosa	43.30	5.00e-113	402.00
IUUC-Pab-098670	Pongo abelii	94.85	0.00e+00	1018.00
IUUC-Pca-100339	Procavia capensis	89.01	0.00e+00	973.00
IUUC-Pva-102174	Pteropus vampyrus	90.24	0.00e+00	1002.00
IUUC-Rno-105310	Rattus norvegicus	90.58	0.00e+00	1001.00
IUUC-Sha-106670	Sarcophilus harrisii	78.13	0.00e+00	783.00
IUUC-Ssc-115785	Sus scrofa	90.09	0.00e+00	854.00
IUUC-Tbe-128036	Tupaia belangeri	90.08	0.00e+00	739.00
IUUC-Ttr-129270	Tursiops truncatus	91.29	0.00e+00	954.00
IUUC-Xtr-132140	Xenopus tropicalis	48.82	6.00e-152	531.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence