iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-46	153.7	147	182
UBD/Beta-Prp	6.70e-75	252.0	16	269

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrt 32
           gHtd+v+c++f    s++++vs+++D t+kvW+l  
   Q: 147  GHTDWVSCVRFspnhSNPIIVSCGWDRTVKVWNLAN 182
           8***********986559***************865 PP

UBD/Beta-Prp

   S: 11   svitcvkf.spdksllatgsrdgtikvwdvttgkl......lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
           + +t ++   +d + ++++srd+t++vw++t+          ++l+gh+ ++++v +s+dg++ ++gs D+t+++wdl +gk+++ ++gh+++vls++
   Q: 16   GWVTQIATnPKDPDTIISASRDKTLIVWKLTRDEDtnygypQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVA 113
           455667775677889***************98666799************************************************************ PP
   S: 102  fspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvs 197
           fs+++  +vsGs+d+ti++w++  + ++   ++gh+++v+cv+++p+    ++vs++ Drtv++W+l++ kl     g h+++ + ++++++g  + s
   Q: 114  FSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHsnPIIVSCGWDRTVKVWNLANCKLKNNHHG-HNGYLNTVTVSPDGSLCTS 210
           *************************9999899**************987569***************88888888887.******************* PP
   S: 198  gsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllk 258
           g++d++  lwdl  g+ ++tl+ h+d ++ + fs  + + ++++  +si+iWdl  ++++ 
   Q: 211  GGKDSKALLWDLNDGKNLYTLE-HNDIINALCFS-PNRYWLCVAYGPSIKIWDLACKKTVE 269
           ********************96.99****99999.888999999*********98887765 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSETLQLRGT LIGHNGWVTQ IATNPKDPDT IISASRDKTL IVWKLTRDED TNYGYPQKRL 60
YGHSHFISDV VLSSDGNYAL SGSWDQTLRL WDLAAGKTTR RFEGHTKDVL SVAFSADNRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGTTTTGTC CTGTCCAACA CTGAACGCTC GCTGACAGTT GGCATCTTAG CGAGCACTGG 60
AACCGGAACT GCCTCTTTTT CTGCCAGCTT GCAGCGCCTT TGGACGTGTT TCCTTCGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-0675--Receptor
KW-1185--Reference proteome
KW-0808--Transferase
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016301--F:kinase activity

KEGG

dme:Dmel_CG7111

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000395	Aegilops tauschii	61.72	5.00e-99	353.00
IUUC-Aml-001935	Ailuropoda melanoleuca	77.14	7.00e-148	515.00
IUUC-Atr-002694	Amborella trichopoda	65.29	2.00e-118	417.00
IUUC-Apl-003918	Anas platyrhynchos	77.78	2.00e-131	460.00
IUUC-Aca-004869	Anolis carolinensis	77.14	7.00e-148	515.00
IUUC-Aly-005806	Arabidopsis lyrata	63.08	3.00e-118	416.00
IUUC-Ath-007584	Arabidopsis thaliana	63.38	3.00e-118	417.00
IUUC-Ago-007720	Ashbya gossypii	52.20	1.00e-94	338.00
IUUC-Acl-008156	Aspergillus clavatus	66.45	3.00e-127	447.00
IUUC-Afl-008684	Aspergillus flavus	66.13	5.00e-127	446.00
IUUC-Afu-008867	Aspergillus fumigatus	67.09	3.00e-129	453.00
IUUC-Ani-009221	Aspergillus nidulans	65.81	1.00e-126	445.00
IUUC-Ang-009843	Aspergillus niger	65.18	4.00e-125	439.00
IUUC-Aor-010193	Aspergillus oryzae	66.13	5.00e-127	446.00
IUUC-Ate-010420	Aspergillus terreus	66.43	3.00e-115	406.00
IUUC-Ame-010884	Astyanax mexicanus	77.46	3.00e-148	516.00
IUUC-Bgr-012064	Blumeria graminis	65.50	5.00e-125	439.00
IUUC-Bta-013357	Bos taurus	77.14	7.00e-148	515.00
IUUC-Bci-013862	Botrytis cinerea	66.13	1.00e-126	445.00
IUUC-Bdi-015057	Brachypodium distachyon	60.68	9.00e-110	389.00
IUUC-Bol-016005	Brassica oleracea	64.11	4.00e-120	423.00
IUUC-Bra-016871	Brassica rapa	63.69	8.00e-120	422.00
IUUC-Cel-018335	Caenorhabditis elegans	63.66	3.00e-115	407.00
IUUC-Cja-019914	Callithrix jacchus	77.14	7.00e-148	515.00
IUUC-Cfa-020755	Canis familiaris	77.14	7.00e-148	515.00
IUUC-Cpo-022377	Cavia porcellus	77.14	4.00e-148	516.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	68.99	9.00e-126	442.00
IUUC-Csa-023025	Chlorocebus sabaeus	77.14	2.00e-147	514.00
IUUC-Cin-025647	Ciona intestinalis	70.66	2.00e-134	470.00
IUUC-Csv-026027	Ciona savignyi	70.66	7.00e-133	465.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	67.84	5.00e-117	412.00
IUUC-Cne-026930	Cryptococcus neoformans	66.77	1.00e-128	451.00
IUUC-Cme-027251	Cyanidioschyzon merolae	61.02	1.00e-113	401.00
IUUC-Dre-028669	Danio rerio	77.14	3.00e-147	513.00
IUUC-Dno-029470	Dasypus novemcinctus	65.71	2.00e-116	411.00
IUUC-Dor-031098	Dipodomys ordii	68.57	9.00e-114	402.00
IUUC-Dse-031255	Dothistroma septosporum	65.30	8.00e-127	445.00
IUUC-Ete-033182	Echinops telfairi	67.73	2.00e-86	311.00
IUUC-Eca-033296	Equus caballus	77.33	1.00e-68	250.00
IUUC-Eeu-034771	Erinaceus europaeus	73.02	2.00e-137	481.00
IUUC-Fca-036315	Felis catus	77.14	7.00e-148	515.00
IUUC-Fal-036990	Ficedula albicollis	73.33	3.00e-79	287.00
IUUC-Fox-037702	Fusarium oxysporum	67.41	4.00e-129	453.00
IUUC-Fso-038384	Fusarium solani	66.88	1.00e-128	451.00
IUUC-Gmo-039630	Gadus morhua	76.38	2.00e-142	497.00
IUUC-Ggr-039985	Gaeumannomyces graminis	67.41	3.00e-129	453.00
IUUC-Gga-040540	Gallus gallus	77.14	7.00e-148	515.00
IUUC-Gac-041316	Gasterosteus aculeatus	74.05	3.00e-142	496.00
IUUC-Gma-042872	Glycine max	63.16	3.00e-117	413.00
IUUC-Ggo-045253	Gorilla gorilla	77.14	7.00e-148	515.00
IUUC-Hsa-046809	Homo sapiens	77.14	7.00e-148	515.00
IUUC-Hvu-047641	Hordeum vulgare	60.68	2.00e-109	387.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	77.14	7.00e-148	515.00
IUUC-Kpa-049214	Komagataella pastoris	54.60	1.00e-92	332.00
IUUC-Lch-049634	Latimeria chalumnae	77.14	6.00e-147	512.00
IUUC-Lpe-050763	Leersia perrieri	59.63	3.00e-108	384.00
IUUC-Loc-052163	Lepisosteus oculatus	77.78	4.00e-148	516.00
IUUC-Lma-053113	Leptosphaeria maculans	66.13	7.00e-127	445.00
IUUC-Laf-054422	Loxodonta africana	77.14	7.00e-148	515.00
IUUC-Mcc-055348	Macaca mulatta	77.14	2.00e-147	514.00
IUUC-Meu-056543	Macropus eugenii	77.14	4.00e-148	516.00
IUUC-Mor-057107	Magnaporthe oryzae	66.77	2.00e-128	451.00
IUUC-Mpo-057487	Magnaporthe poae	67.09	8.00e-129	452.00
IUUC-Mtr-058808	Medicago truncatula	62.85	1.00e-116	411.00
IUUC-Mla-058909	Melampsora laricipopulina	66.88	2.00e-129	453.00
IUUC-Mga-059387	Meleagris gallopavo	77.14	7.00e-148	515.00
IUUC-Mvi-060392	Microbotryum violaceum	65.81	6.00e-127	446.00
IUUC-Mmr-061141	Microcebus murinus	70.63	5.00e-109	386.00
IUUC-Mdo-062932	Monodelphis domestica	77.14	7.00e-148	515.00
IUUC-Mmu-064132	Mus musculus	77.14	7.00e-148	515.00
IUUC-Mac-064447	Musa acuminata	57.72	2.00e-101	361.00
IUUC-Mpu-066721	Mustela putorius furo	76.19	2.00e-144	504.00
IUUC-Mlu-068221	Myotis lucifugus	76.51	5.00e-138	482.00
IUUC-Nfi-068344	Neosartorya fischeri	67.09	3.00e-129	453.00
IUUC-Ncr-068722	Neurospora crassa	66.77	4.00e-128	449.00
IUUC-Nle-069865	Nomascus leucogenys	77.14	1.00e-147	515.00
IUUC-Opr-071100	Ochotona princeps	63.81	5.00e-115	406.00
IUUC-Ont-072287	Oreochromis niloticus	77.46	2.00e-148	516.00
IUUC-Oan-072788	Ornithorhynchus anatinus	77.14	7.00e-148	515.00
IUUC-Ocu-073844	Oryctolagus cuniculus	75.24	3.00e-142	496.00
IUUC-Oba-075652	Oryza barthii	56.72	2.00e-100	358.00
IUUC-Obr-076099	Oryza brachyantha	59.94	9.00e-108	382.00
IUUC-Ogl-077804	Oryza glaberrima	60.55	1.00e-109	388.00
IUUC-Ogu-078035	Oryza glumaepatula	61.23	7.00e-110	389.00
IUUC-Oin-079327	Oryza indica	61.23	7.00e-110	389.00
IUUC-Olo-081084	Oryza longistaminata	61.23	7.00e-110	389.00
IUUC-Ome-081366	Oryza meridionalis	60.55	1.00e-109	388.00
IUUC-Oni-082682	Oryza nivara	60.55	1.00e-109	388.00
IUUC-Opu-084010	Oryza punctata	59.94	7.00e-109	385.00
IUUC-Oru-084358	Oryza rufipogon	60.55	1.00e-109	388.00
IUUC-Osa-085296	Oryza sativa	60.55	1.00e-109	388.00
IUUC-Ola-086400	Oryzias latipes	77.14	7.00e-148	515.00
IUUC-Olu-087817	Ostreococcus lucimarinus	67.52	3.00e-126	443.00
IUUC-Oga-088811	Otolemur garnettii	77.14	7.00e-148	515.00
IUUC-Oar-089962	Ovis aries	77.14	7.00e-148	515.00
IUUC-Ptr-091340	Pan troglodytes	77.14	7.00e-148	515.00
IUUC-Pan-091946	Papio anubis	77.14	1.00e-147	514.00
IUUC-Pma-094535	Petromyzon marinus	78.73	6.00e-150	522.00
IUUC-Pno-095100	Phaeosphaeria nodorum	69.95	5.00e-90	322.00
IUUC-Ppa-095752	Physcomitrella patens	69.11	5.00e-127	446.00
IUUC-Pfo-097311	Poecilia formosa	76.83	4.00e-147	513.00
IUUC-Pab-097863	Pongo abelii	77.14	6.00e-148	516.00
IUUC-Pop-099345	Populus trichocarpa	62.96	1.00e-116	411.00
IUUC-Pca-100594	Procavia capensis	76.51	2.00e-146	510.00
IUUC-Ppe-101743	Prunus persica	63.38	3.00e-117	414.00
IUUC-Pva-102746	Pteropus vampyrus	63.81	3.00e-114	404.00
IUUC-Pgr-103375	Puccinia graminis	52.06	9.00e-87	312.00
IUUC-Ptt-103839	Puccinia triticina	67.52	1.00e-127	448.00
IUUC-Pte-104026	Pyrenophora teres	66.13	7.00e-127	445.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	66.13	9.00e-127	445.00
IUUC-Rno-104964	Rattus norvegicus	77.14	7.00e-148	515.00
IUUC-Sce-106224	Saccharomyces cerevisiae	52.38	2.00e-91	327.00
IUUC-Sha-107409	Sarcophilus harrisii	77.14	7.00e-148	515.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	61.78	1.00e-117	415.00
IUUC-Spo-108297	Schizosaccharomyces pombe	59.55	3.00e-114	403.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	66.13	1.00e-126	445.00
IUUC-Smo-109017	Selaginella moellendorffii	63.61	2.00e-116	411.00
IUUC-Sit-110060	Setaria italica	61.85	3.00e-112	397.00
IUUC-Sly-111496	Solanum lycopersicum	62.93	2.00e-116	410.00
IUUC-Stu-112757	Solanum tuberosum	62.62	2.00e-113	400.00
IUUC-Sar-113173	Sorex araneus	77.14	7.00e-148	515.00
IUUC-Sbi-114681	Sorghum bicolor	60.49	2.00e-111	394.00
IUUC-Sre-115107	Sporisorium reilianum	66.45	3.00e-130	456.00
IUUC-Ssc-116218	Sus scrofa	73.97	7.00e-142	495.00
IUUC-Tru-118202	Takifugu rubripes	77.46	1.00e-147	514.00
IUUC-Tni-120260	Tetraodon nigroviridis	76.83	3.00e-147	513.00
IUUC-Tca-120951	Theobroma cacao	61.92	3.00e-116	410.00
IUUC-Tre-121961	Trichoderma reesei	67.41	2.00e-128	451.00
IUUC-Tvi-122447	Trichoderma virens	67.41	4.00e-129	453.00
IUUC-Tae-125589	Triticum aestivum	60.68	2.00e-109	387.00
IUUC-Tur-126335	Triticum urartu	63.67	3.00e-97	347.00
IUUC-Tme-127105	Tuber melanosporum	62.94	6.00e-118	416.00
IUUC-Tbe-128021	Tupaia belangeri	61.81	2.00e-65	241.00
IUUC-Ttr-128637	Tursiops truncatus	66.67	2.00e-123	434.00
IUUC-Uma-129634	Ustilago maydis	67.09	7.00e-131	459.00
IUUC-Vda-129923	Verticillium dahliae	66.77	6.00e-128	449.00
IUUC-Vpa-130410	Vicugna pacos	82.42	2.00e-81	294.00
IUUC-Vvi-131115	Vitis vinifera	62.46	6.00e-118	416.00
IUUC-Xtr-132105	Xenopus tropicalis	77.78	3.00e-149	520.00
IUUC-Xma-133875	Xiphophorus maculatus	77.14	2.00e-147	514.00
IUUC-Yli-134624	Yarrowia lipolytica	58.26	3.00e-109	387.00
IUUC-Zma-134711	Zea mays	60.92	3.00e-109	387.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence