iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	8.20e-17	62.7	255	328

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 4    eqatlqiRlpdGkrlvrkFpssttleqiyqfve.yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsll 78
           +++++qiRl+dG+rlv++F+s++++ ++++f+   +  +  + F Lv++fP ++l++e+   tlqea+++++ +l+
   Q: 255  PTTKIQIRLADGSRLVQRFNSTHRILDVRDFIVrSRPEFATTDFILVTSFPSKELTDETV--TLQEADILNTVILQ 328
           589******************************8888999999*****************..*********99985 PP

Organism

Mus musculus

Functional Description
(View)

Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity (By similarity).

Protein Sequence
(Fasta)

MAEGGRAEPE EQERGSSRPR PPSARDLQLA LAELYEDEMK CKSSKPDRST PATCRSPRTP 60
PHRLYSGDHK YDGLHIVQPP TGKIVNELFK EAREHGAVPL NEATRSSRED KTKSFTGGGY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCCGGGGC AGGCGCCGCA AGCGGGTGAA AGATGGCGGA GGGTGGCCGT GCGGAGCCGG 60
AGGAGCAGGA GCGTGGGTCC TCCAGGCCAC GGCCCCCAAG TGCGCGGGAC TTACAGGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR012989--SEP_domain
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS51399--SEP
PS50033--UBX

Pfam

PF08059--SEP
PF00789--UBX

SMART

SM00553--SEP
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0005634--C:nucleus
GO:0043130--F:ubiquitin binding
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0031468--P:nuclear envelope reassembly
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

mmu:68053

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000550	Aegilops tauschii	36.68	2.00e-35	142.00
IUUC-Aml-001637	Ailuropoda melanoleuca	86.10	1.00e-167	582.00
IUUC-Apl-003738	Anas platyrhynchos	71.86	1.00e-122	432.00
IUUC-Aca-005097	Anolis carolinensis	69.07	6.00e-124	436.00
IUUC-Ath-007064	Arabidopsis thaliana	36.50	4.00e-34	138.00
IUUC-Acl-008176	Aspergillus clavatus	39.11	2.00e-29	123.00
IUUC-Afl-008553	Aspergillus flavus	36.31	8.00e-26	111.00
IUUC-Aor-010016	Aspergillus oryzae	36.31	9.00e-26	110.00
IUUC-Bgr-012256	Blumeria graminis	34.95	1.00e-27	117.00
IUUC-Bta-012629	Bos taurus	85.11	5.00e-149	520.00
IUUC-Bdi-014204	Brachypodium distachyon	32.75	2.00e-33	136.00
IUUC-Bra-017734	Brassica rapa	35.64	2.00e-34	139.00
IUUC-Cja-019732	Callithrix jacchus	77.64	5.00e-135	473.00
IUUC-Cfa-021132	Canis familiaris	86.10	3.00e-168	584.00
IUUC-Cpo-021389	Cavia porcellus	85.90	3.00e-161	560.00
IUUC-Csa-023362	Chlorocebus sabaeus	85.50	5.00e-163	566.00
IUUC-Cgl-026628	Colletotrichum gloeosporioides	32.78	9.00e-24	104.00
IUUC-Dno-029956	Dasypus novemcinctus	84.68	4.00e-154	537.00
IUUC-Dor-031124	Dipodomys ordii	77.27	3.00e-130	457.00
IUUC-Eca-034063	Equus caballus	85.80	1.00e-167	582.00
IUUC-Fca-035606	Felis catus	85.80	1.00e-166	578.00
IUUC-Fal-036923	Ficedula albicollis	71.08	5.00e-121	427.00
IUUC-Ggr-039971	Gaeumannomyces graminis	28.50	1.00e-14	74.30
IUUC-Gga-040906	Gallus gallus	72.46	6.00e-137	480.00
IUUC-Gma-043511	Glycine max	34.67	5.00e-36	144.00
IUUC-Ggo-044801	Gorilla gorilla	86.04	2.00e-158	551.00
IUUC-Hsa-046853	Homo sapiens	86.04	2.00e-158	551.00
IUUC-Hvu-047203	Hordeum vulgare	33.07	1.00e-31	130.00
IUUC-Itr-047910	Ictidomys tridecemlineatus	91.22	6.00e-142	496.00
IUUC-Lpe-051122	Leersia perrieri	35.48	1.00e-34	140.00
IUUC-Lma-053319	Leptosphaeria maculans	39.39	1.00e-34	140.00
IUUC-Laf-053854	Loxodonta africana	82.59	5.00e-145	506.00
IUUC-Mcc-055607	Macaca mulatta	85.20	1.00e-158	552.00
IUUC-Mtr-058376	Medicago truncatula	37.91	3.00e-34	139.00
IUUC-Mga-059714	Meleagris gallopavo	72.78	2.00e-132	465.00
IUUC-Mmr-061091	Microcebus murinus	88.64	2.00e-162	564.00
IUUC-Mdo-062985	Monodelphis domestica	77.41	2.00e-139	488.00
IUUC-Mac-065403	Musa acuminata	38.66	1.00e-32	134.00
IUUC-Mpu-066168	Mustela putorius furo	87.34	2.00e-164	571.00
IUUC-Mlu-067562	Myotis lucifugus	83.38	5.00e-154	536.00
IUUC-Nfi-068609	Neosartorya fischeri	37.43	6.00e-29	121.00
IUUC-Ncr-068786	Neurospora crassa	33.70	4.00e-24	105.00
IUUC-Nle-069639	Nomascus leucogenys	86.04	9.00e-159	552.00
IUUC-Oan-073007	Ornithorhynchus anatinus	79.93	9.00e-144	502.00
IUUC-Ocu-074507	Oryctolagus cuniculus	85.80	1.00e-161	561.00
IUUC-Oba-075011	Oryza barthii	34.44	7.00e-34	137.00
IUUC-Obr-076164	Oryza brachyantha	36.62	2.00e-28	119.00
IUUC-Ogl-077805	Oryza glaberrima	34.44	7.00e-34	137.00
IUUC-Ogu-078942	Oryza glumaepatula	34.07	2.00e-34	139.00
IUUC-Oin-079497	Oryza indica	34.16	1.00e-33	137.00
IUUC-Olo-080254	Oryza longistaminata	37.04	6.00e-30	125.00
IUUC-Ome-081766	Oryza meridionalis	35.77	2.00e-31	131.00
IUUC-Oni-082258	Oryza nivara	34.44	7.00e-34	137.00
IUUC-Opu-083365	Oryza punctata	34.78	2.00e-35	143.00
IUUC-Oru-084748	Oryza rufipogon	34.07	2.00e-34	139.00
IUUC-Osa-085359	Oryza sativa	34.44	7.00e-34	137.00
IUUC-Oga-088292	Otolemur garnettii	75.90	9.00e-136	476.00
IUUC-Oar-090236	Ovis aries	83.82	2.00e-144	504.00
IUUC-Ptr-090664	Pan troglodytes	86.04	2.00e-158	551.00
IUUC-Pan-092072	Papio anubis	86.18	3.00e-157	547.00
IUUC-Psi-093486	Pelodiscus sinensis	76.05	3.00e-127	447.00
IUUC-Pno-094769	Phaeosphaeria nodorum	37.88	2.00e-34	140.00
IUUC-Pab-097813	Pongo abelii	86.04	2.00e-158	551.00
IUUC-Pca-100985	Procavia capensis	72.39	9.00e-102	363.00
IUUC-Ppe-101417	Prunus persica	34.66	2.00e-35	143.00
IUUC-Pva-102600	Pteropus vampyrus	86.11	1.00e-162	565.00
IUUC-Pte-104083	Pyrenophora teres	40.61	5.00e-40	158.00
IUUC-Pyt-104504	Pyrenophora triticirepentis	40.20	6.00e-35	141.00
IUUC-Rno-105047	Rattus norvegicus	91.88	5.00e-169	586.00
IUUC-Sha-106777	Sarcophilus harrisii	73.49	1.00e-66	245.00
IUUC-Sja-107717	Schizosaccharomyces japonicus	33.58	4.00e-31	129.00
IUUC-Sit-110328	Setaria italica	35.61	8.00e-34	138.00
IUUC-Sbi-114513	Sorghum bicolor	36.29	2.00e-35	143.00
IUUC-Sre-115176	Sporisorium reilianum	37.63	9.00e-32	131.00
IUUC-Ssc-115936	Sus scrofa	86.73	3.00e-148	517.00
IUUC-Tgu-116752	Taeniopygia guttata	71.85	8.00e-127	446.00
IUUC-Tsy-119015	Tarsius syrichta	75.97	3.00e-132	464.00
IUUC-Tca-121370	Theobroma cacao	33.10	5.00e-30	125.00
IUUC-Ttr-128760	Tursiops truncatus	85.94	6.00e-151	526.00
IUUC-Vpa-130155	Vicugna pacos	85.15	4.00e-146	510.00
IUUC-Vvi-131338	Vitis vinifera	33.10	3.00e-32	132.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence