iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000015778.3	ENSMMUT00000073239.1	ENSMMUP00000053818.1
ENSMMUG00000015778.3	ENSMMUT00000018424.3	ENSMMUP00000017251.3
ENSMMUG00000015778.3	ENSMMUT00000022153.3	ENSMMUP00000020726.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.70e-07	31.7	620	662

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplv..lpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +Cle f++g l+  lpCgHvfh++C+ +w     ++ ++  CP+Cr
   Q: 620  CVVCLENFENGCLLmgLPCGHVFHQNCIVMW-----LAGGRHCCPVCR 662
           **********87776688*************.....89*********8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MWLKLFFLLL YFLVLFVLAR FFEAIVWYET GIFATQLVDP VALSFKKLKT ILECRGLGYS 60
GLPEKKDVRE LVEKSGDLME GELYSALKEE ASESVSSTNF SGEMHFYELV EDTKDGIWLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGACGGCGC CGGGTGGCCC GCGCGTGGAC ACGGGGCCCT CGCCCAAGCT GCCACCGAGC 60
CGCGGCCTCC GCCCTCGACC CTTCTCTCTC CCGTATTCCG AGCTCTCTGG AAAGAGAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR012336--Thioredoxin-like_fold
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

mcc:698072

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002130	Ailuropoda melanoleuca	97.59	0.00e+00	1279.00
IUUC-Apl-004099	Anas platyrhynchos	86.85	0.00e+00	1120.00
IUUC-Aca-004500	Anolis carolinensis	85.16	0.00e+00	1118.00
IUUC-Ame-011513	Astyanax mexicanus	71.41	0.00e+00	931.00
IUUC-Bta-012824	Bos taurus	97.29	0.00e+00	1283.00
IUUC-Bdi-014038	Brachypodium distachyon	54.35	3.00e-10	58.50
IUUC-Bra-017504	Brassica rapa	54.55	4.00e-10	57.80
IUUC-Cja-019429	Callithrix jacchus	97.74	0.00e+00	1308.00
IUUC-Cfa-020110	Canis familiaris	97.44	0.00e+00	1312.00
IUUC-Cpo-021413	Cavia porcellus	97.69	0.00e+00	1012.00
IUUC-Csa-023111	Chlorocebus sabaeus	99.18	0.00e+00	1189.00
IUUC-Dre-027675	Danio rerio	71.19	0.00e+00	933.00
IUUC-Dno-029645	Dasypus novemcinctus	94.06	0.00e+00	1156.00
IUUC-Dor-030871	Dipodomys ordii	94.81	0.00e+00	800.00
IUUC-Ete-032670	Echinops telfairi	93.95	0.00e+00	650.00
IUUC-Eca-033322	Equus caballus	97.29	0.00e+00	1276.00
IUUC-Eeu-035071	Erinaceus europaeus	96.42	9.00e-155	540.00
IUUC-Fca-036356	Felis catus	97.29	0.00e+00	1290.00
IUUC-Fal-036861	Ficedula albicollis	85.45	0.00e+00	1136.00
IUUC-Gmo-039251	Gadus morhua	60.09	0.00e+00	746.00
IUUC-Gga-040659	Gallus gallus	86.67	0.00e+00	1150.00
IUUC-Gac-042187	Gasterosteus aculeatus	63.10	0.00e+00	786.00
IUUC-Ggo-044883	Gorilla gorilla	98.94	0.00e+00	1340.00
IUUC-Hsa-045756	Homo sapiens	98.94	0.00e+00	1326.00
IUUC-Hvu-047185	Hordeum vulgare	47.17	3.00e-10	57.40
IUUC-Itr-048705	Ictidomys tridecemlineatus	87.15	0.00e+00	1110.00
IUUC-Lch-049872	Latimeria chalumnae	78.64	0.00e+00	971.00
IUUC-Lpe-051679	Leersia perrieri	60.00	8.00e-11	62.40
IUUC-Loc-051795	Lepisosteus oculatus	76.66	0.00e+00	976.00
IUUC-Laf-053807	Loxodonta africana	96.38	0.00e+00	1298.00
IUUC-Meu-056570	Macropus eugenii	86.56	0.00e+00	1066.00
IUUC-Mga-059758	Meleagris gallopavo	86.93	0.00e+00	1020.00
IUUC-Mvi-060247	Microbotryum violaceum	52.27	1.00e-10	61.60
IUUC-Mmr-061620	Microcebus murinus	93.93	0.00e+00	637.00
IUUC-Mdo-062398	Monodelphis domestica	83.58	0.00e+00	1107.00
IUUC-Mmu-064279	Mus musculus	94.42	0.00e+00	1234.00
IUUC-Mpu-065770	Mustela putorius furo	97.74	0.00e+00	1283.00
IUUC-Mlu-067764	Myotis lucifugus	93.39	0.00e+00	1263.00
IUUC-Nle-069363	Nomascus leucogenys	98.64	0.00e+00	1326.00
IUUC-Opr-070664	Ochotona princeps	94.12	0.00e+00	1239.00
IUUC-Ont-072466	Oreochromis niloticus	63.14	0.00e+00	823.00
IUUC-Oan-073047	Ornithorhynchus anatinus	82.70	0.00e+00	959.00
IUUC-Ocu-074240	Oryctolagus cuniculus	93.00	0.00e+00	1250.00
IUUC-Oba-075208	Oryza barthii	49.06	3.00e-11	61.60
IUUC-Ogl-077486	Oryza glaberrima	49.06	3.00e-11	61.60
IUUC-Ogu-079028	Oryza glumaepatula	49.06	3.00e-10	59.30
IUUC-Olo-080618	Oryza longistaminata	49.06	3.00e-11	61.60
IUUC-Ome-081540	Oryza meridionalis	45.45	3.00e-11	61.20
IUUC-Oru-084388	Oryza rufipogon	49.06	3.00e-11	61.60
IUUC-Osa-086245	Oryza sativa	49.06	3.00e-11	61.60
IUUC-Ola-086352	Oryzias latipes	61.97	0.00e+00	756.00
IUUC-Oga-088582	Otolemur garnettii	97.74	0.00e+00	1315.00
IUUC-Oar-090324	Ovis aries	96.26	0.00e+00	1274.00
IUUC-Pan-092792	Papio anubis	99.25	0.00e+00	1334.00
IUUC-Psi-092964	Pelodiscus sinensis	90.20	0.00e+00	1163.00
IUUC-Pma-094186	Petromyzon marinus	53.00	0.00e+00	680.00
IUUC-Pfo-097169	Poecilia formosa	61.89	0.00e+00	800.00
IUUC-Pab-098549	Pongo abelii	98.94	0.00e+00	1327.00
IUUC-Pca-100113	Procavia capensis	91.13	0.00e+00	1060.00
IUUC-Ppe-101266	Prunus persica	51.11	5.00e-12	62.40
IUUC-Pva-102543	Pteropus vampyrus	93.39	0.00e+00	798.00
IUUC-Rno-105676	Rattus norvegicus	94.60	0.00e+00	1201.00
IUUC-Sha-106596	Sarcophilus harrisii	90.31	0.00e+00	707.00
IUUC-Sit-109739	Setaria italica	50.00	2.00e-09	55.10
IUUC-Sly-111354	Solanum lycopersicum	52.17	2.00e-12	64.30
IUUC-Sar-113147	Sorex araneus	96.72	0.00e+00	1159.00
IUUC-Ssc-115585	Sus scrofa	96.23	0.00e+00	1262.00
IUUC-Tgu-117258	Taeniopygia guttata	85.61	0.00e+00	1133.00
IUUC-Tsy-119127	Tarsius syrichta	94.41	0.00e+00	1137.00
IUUC-Tbe-128054	Tupaia belangeri	96.68	0.00e+00	1081.00
IUUC-Ttr-128931	Tursiops truncatus	98.66	0.00e+00	870.00
IUUC-Vpa-130826	Vicugna pacos	96.02	0.00e+00	1170.00
IUUC-Xtr-132828	Xenopus tropicalis	81.44	0.00e+00	1099.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence