iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059777

UUCD1 version

UUC-MeG-00088

Ensembl Protein ID

ENSMGAP00000001246.2

UniProt Accession

G1MSF9; G1MSF9_MELGA

Protein Name

Uncharacterized protein

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000001750.2	ENSMGAT00000001898.2	ENSMGAP00000001246.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-32	109.5	407	443
UBD/Beta-Prp	2.60e-62	210.4	317	607

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v+
   Q: 407  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVC 443
           8***********64489****************9887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           +++++h++ +++v+fsp+++llatg++d+++k+w+v    +    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   htl
   Q: 317  CVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVLGDRCepKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDNRLRHTL 405
           7899**********************************999999********************************************* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           +gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c  + +++g     +c  + +++++++sG+ D+++r+Wd++t++++++l+  
   Q: 406  TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCNIKtVFAGS----SCNDIVCTEQCVMSGHFDKKIRFWDIRTESIVKELE-- 488
           **************************************975344444....4888888889*************************6.. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
             ++++ l+++s+++el+++s+d  +k+ dl+ g + +t+ ++     +  ++v fsp++++++ gs+Dg +++W++ +g+l +tl++h
   Q: 489  LLGRITALDLNSERTELLTCSRDDLLKIIDLRVGAVKQTFSAQGfkcgSDWTRVVFSPDGNYVAAGSADGALYVWNVLTGKLERTLAKH 577
           69********************************99888888887788777779*********************************** PP
   S: 264  nssvisvavlsfgdnvlvlgsedskvniwk 293
           +ss+i   ++s+ + ++v++++ +k+ +w+
   Q: 578  HSSSINAVAWSPAGAHVVSVDKGNKAVLWS 607
           **********************99999996 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

CACASAEGPF PKWRRRVDAV TPRRSQLKNK LFFLIVLLDN KLLEKSDLHA VLADKLQAEK 60
YDMQSRHEIS PGHDGTWNDA QLQELAQLKI KHQEELTELH KKRGELAQSV IDLNNQMQQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCGCATGCG CCTCTGCTGA GGGCCCCTTC CCAAAATGGC GGCGCCGGGT GGATGCCGTG 60
ACCCCGCGCC GCTCTCAAGA TGGCGGCAGC GCGCGGCTCG CCTCATGAGT GGGCGCGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR012284--6PGD_dom_3
IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	27.78	1.00e-30	127.00
IUUC-Aml-002242	Ailuropoda melanoleuca	83.45	0.00e+00	966.00
IUUC-Atr-003073	Amborella trichopoda	25.09	7.00e-30	124.00
IUUC-Apl-003384	Anas platyrhynchos	97.92	0.00e+00	1159.00
IUUC-Aca-004962	Anolis carolinensis	84.58	0.00e+00	1016.00
IUUC-Aly-005435	Arabidopsis lyrata	34.54	3.00e-44	172.00
IUUC-Ath-006948	Arabidopsis thaliana	34.54	8.00e-45	174.00
IUUC-Ame-010915	Astyanax mexicanus	80.98	3.00e-158	550.00
IUUC-Bta-012388	Bos taurus	83.60	0.00e+00	1044.00
IUUC-Bdi-014231	Brachypodium distachyon	24.95	1.00e-37	150.00
IUUC-Bol-016174	Brassica oleracea	35.53	2.00e-45	176.00
IUUC-Bra-017165	Brassica rapa	34.87	6.00e-45	174.00
IUUC-Cel-018131	Caenorhabditis elegans	30.80	7.00e-65	241.00
IUUC-Cja-018898	Callithrix jacchus	74.75	0.00e+00	864.00
IUUC-Cfa-020484	Canis familiaris	85.50	0.00e+00	1039.00
IUUC-Cpo-022156	Cavia porcellus	84.33	0.00e+00	1015.00
IUUC-Csa-024019	Chlorocebus sabaeus	81.83	0.00e+00	980.00
IUUC-Cho-024311	Choloepus hoffmanni	71.31	0.00e+00	858.00
IUUC-Cin-025260	Ciona intestinalis	37.12	1.00e-100	360.00
IUUC-Csv-025836	Ciona savignyi	44.98	6.00e-48	182.00
IUUC-Dre-027702	Danio rerio	72.33	0.00e+00	884.00
IUUC-Dno-029728	Dasypus novemcinctus	81.69	0.00e+00	1031.00
IUUC-Dor-030587	Dipodomys ordii	70.29	6.00e-95	341.00
IUUC-Dme-031595	Drosophila melanogaster	39.04	2.00e-110	392.00
IUUC-Ete-032969	Echinops telfairi	71.63	0.00e+00	720.00
IUUC-Eca-034214	Equus caballus	89.27	0.00e+00	887.00
IUUC-Eeu-034537	Erinaceus europaeus	83.05	0.00e+00	843.00
IUUC-Fca-036005	Felis catus	85.33	0.00e+00	999.00
IUUC-Fal-037593	Ficedula albicollis	95.38	0.00e+00	1095.00
IUUC-Gmo-039042	Gadus morhua	63.38	0.00e+00	672.00
IUUC-Gga-040986	Gallus gallus	93.67	0.00e+00	1149.00
IUUC-Gac-041351	Gasterosteus aculeatus	72.01	0.00e+00	900.00
IUUC-Gma-043265	Glycine max	29.06	2.00e-52	199.00
IUUC-Ggo-045427	Gorilla gorilla	82.01	0.00e+00	998.00
IUUC-Hsa-046632	Homo sapiens	84.17	0.00e+00	1019.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	80.53	0.00e+00	961.00
IUUC-Lch-049439	Latimeria chalumnae	48.07	8.00e-142	496.00
IUUC-Lpe-051254	Leersia perrieri	30.03	2.00e-37	149.00
IUUC-Loc-052610	Lepisosteus oculatus	74.59	0.00e+00	905.00
IUUC-Laf-053936	Loxodonta africana	80.32	0.00e+00	996.00
IUUC-Mcc-055504	Macaca mulatta	79.72	0.00e+00	1019.00
IUUC-Meu-056516	Macropus eugenii	78.93	0.00e+00	952.00
IUUC-Mtr-058062	Medicago truncatula	26.69	6.00e-47	181.00
IUUC-Mmr-061298	Microcebus murinus	83.60	0.00e+00	1016.00
IUUC-Mdo-062969	Monodelphis domestica	83.95	0.00e+00	1039.00
IUUC-Mmu-064076	Mus musculus	81.14	0.00e+00	983.00
IUUC-Mac-065161	Musa acuminata	25.00	3.00e-38	152.00
IUUC-Mpu-066196	Mustela putorius furo	83.60	0.00e+00	1018.00
IUUC-Mlu-067651	Myotis lucifugus	84.36	0.00e+00	1025.00
IUUC-Nle-069853	Nomascus leucogenys	83.17	0.00e+00	1004.00
IUUC-Opr-070350	Ochotona princeps	87.38	3.00e-109	388.00
IUUC-Ont-072489	Oreochromis niloticus	72.39	0.00e+00	889.00
IUUC-Oan-072703	Ornithorhynchus anatinus	78.35	0.00e+00	934.00
IUUC-Ocu-074205	Oryctolagus cuniculus	81.07	0.00e+00	1006.00
IUUC-Oba-075619	Oryza barthii	30.42	1.00e-35	144.00
IUUC-Obr-076632	Oryza brachyantha	29.47	1.00e-37	150.00
IUUC-Ogl-077671	Oryza glaberrima	30.42	1.00e-35	144.00
IUUC-Ogu-078052	Oryza glumaepatula	30.42	1.00e-35	144.00
IUUC-Oin-079611	Oryza indica	30.07	2.00e-33	136.00
IUUC-Olo-080408	Oryza longistaminata	30.42	2.00e-35	143.00
IUUC-Ome-081560	Oryza meridionalis	30.42	1.00e-35	144.00
IUUC-Oni-082145	Oryza nivara	30.42	1.00e-35	144.00
IUUC-Opu-083918	Oryza punctata	29.47	4.00e-35	142.00
IUUC-Oru-084858	Oryza rufipogon	30.07	3.00e-33	135.00
IUUC-Osa-086277	Oryza sativa	30.07	2.00e-33	136.00
IUUC-Ola-086816	Oryzias latipes	68.00	3.00e-99	354.00
IUUC-Olu-087622	Ostreococcus lucimarinus	35.33	5.00e-43	167.00
IUUC-Oga-088765	Otolemur garnettii	80.70	0.00e+00	934.00
IUUC-Oar-090196	Ovis aries	83.51	0.00e+00	942.00
IUUC-Ptr-091676	Pan troglodytes	84.33	0.00e+00	1020.00
IUUC-Pan-092068	Papio anubis	82.66	0.00e+00	1007.00
IUUC-Psi-093367	Pelodiscus sinensis	90.17	0.00e+00	1065.00
IUUC-Ppa-095699	Physcomitrella patens	29.08	2.00e-40	160.00
IUUC-Pfo-096067	Poecilia formosa	72.45	0.00e+00	866.00
IUUC-Pab-098111	Pongo abelii	82.01	0.00e+00	999.00
IUUC-Pop-099116	Populus trichocarpa	33.44	6.00e-43	168.00
IUUC-Pca-100680	Procavia capensis	72.84	0.00e+00	828.00
IUUC-Ppe-101790	Prunus persica	25.58	7.00e-46	177.00
IUUC-Pva-102871	Pteropus vampyrus	82.65	0.00e+00	972.00
IUUC-Rno-106088	Rattus norvegicus	80.49	0.00e+00	974.00
IUUC-Sha-106984	Sarcophilus harrisii	88.73	0.00e+00	1063.00
IUUC-Smo-109404	Selaginella moellendorffii	33.00	9.00e-42	164.00
IUUC-Sit-110828	Setaria italica	26.67	7.00e-44	171.00
IUUC-Sly-111009	Solanum lycopersicum	25.15	1.00e-46	180.00
IUUC-Stu-112370	Solanum tuberosum	26.10	3.00e-47	182.00
IUUC-Sar-113659	Sorex araneus	60.61	4.00e-87	313.00
IUUC-Sbi-114819	Sorghum bicolor	24.95	1.00e-40	160.00
IUUC-Ssc-116241	Sus scrofa	84.04	0.00e+00	1007.00
IUUC-Tgu-116576	Taeniopygia guttata	94.67	0.00e+00	1154.00
IUUC-Tru-118336	Takifugu rubripes	65.58	0.00e+00	750.00
IUUC-Tsy-119006	Tarsius syrichta	79.71	0.00e+00	957.00
IUUC-Tni-120300	Tetraodon nigroviridis	74.29	0.00e+00	874.00
IUUC-Tca-121002	Theobroma cacao	28.02	2.00e-51	196.00
IUUC-Tae-124868	Triticum aestivum	28.43	1.00e-31	130.00
IUUC-Tur-126463	Triticum urartu	27.78	5.00e-31	129.00
IUUC-Tbe-127631	Tupaia belangeri	88.49	0.00e+00	852.00
IUUC-Ttr-129005	Tursiops truncatus	78.09	2.00e-152	531.00
IUUC-Vpa-130246	Vicugna pacos	74.39	0.00e+00	743.00
IUUC-Vvi-130878	Vitis vinifera	34.81	1.00e-44	173.00
IUUC-Xtr-132798	Xenopus tropicalis	72.22	0.00e+00	856.00
IUUC-Xma-133264	Xiphophorus maculatus	72.41	0.00e+00	868.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence