iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	JASPAR	miRTarBase	microRNA
TRANSFAC	RepTar	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Other	96.07	1.00e-102	370.00	IUUC-Hsa-046919

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

Belongs to the Antp homeobox family. Deformed subfamily.

Protein Sequence
(Fasta)

MAMSSFLINS NYVDPKFPPC EEYSQSDYLP SDHSPGYYAG GQRRESGFQP EAAFGRRAPC 60
TVQRYAACRD PGPPPPPPPP PPPPPPGLSP RAPVQPTAGA LLPEPGQRSE AVSSSPPPPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTCCCTCT TATCCTGGGG AGGAGATGGG GCCCTATGGG AGTCAGAGAA AGGTTGGTGG 60
AGATTAGGTA GGGCAGGGGT GGGGGCTACA CCCGCAGCCC CAACTTCTGA GGGATGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0371--Homeobox
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR009057--Homeobox-like
IPR017995--Homeobox_antennapedia
IPR001827--Homeobox_Antennapedia_CS
IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR020479--Homeobox_metazoa

PROSITE

PS00032--ANTENNAPEDIA
PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2

Pfam

PF00046--Homeobox

PRINTS

PR00025--ANTENNAPEDIA
PR00024--HOMEOBOX

SMART

SM00389--HOX

Gene Ontology

GO:0005813--C:centrosome
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0009952--P:anterior/posterior pattern specification
GO:0048539--P:bone marrow development
GO:0008283--P:cell proliferation
GO:0060216--P:definitive hemopoiesis
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0060218--P:hematopoietic stem cell differentiation
GO:0030097--P:hemopoiesis
GO:0002011--P:morphogenesis of an epithelial sheet
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:2000738--P:positive regulation of stem cell differentiation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0048705--P:skeletal system morphogenesis
GO:0048103--P:somatic stem cell division
GO:0048536--P:spleen development
GO:0006351--P:transcription, DNA-templated

KEGG

mmu:15412

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002156	Ailuropoda melanoleuca	66.09	1.00e-72	265.00
IUUC-Aca-004281	Anolis carolinensis	68.40	3.00e-76	278.00
IUUC-Ame-011424	Astyanax mexicanus	65.50	1.00e-71	262.00
IUUC-Bta-013580	Bos taurus	92.17	7.00e-103	366.00
IUUC-Bdi-014316	Brachypodium distachyon	47.54	1.00e-09	57.40
IUUC-Bra-017918	Brassica rapa	49.15	1.00e-09	57.00
IUUC-Cja-019422	Callithrix jacchus	88.11	7.00e-101	359.00
IUUC-Cfa-020551	Canis familiaris	88.89	2.00e-106	378.00
IUUC-Cpo-022099	Cavia porcellus	98.37	8.00e-64	236.00
IUUC-Csa-023337	Chlorocebus sabaeus	89.96	2.00e-100	358.00
IUUC-Dre-027947	Danio rerio	66.38	4.00e-75	274.00
IUUC-Dno-029094	Dasypus novemcinctus	89.04	3.00e-99	354.00
IUUC-Dme-031651	Drosophila melanogaster	29.82	1.10e+00	30.40
IUUC-Fca-035652	Felis catus	100.00	2.00e-61	228.00
IUUC-Gac-041606	Gasterosteus aculeatus	62.45	3.00e-70	258.00
IUUC-Hsa-046919	Homo sapiens	89.91	7.00e-100	356.00
IUUC-Itr-048677	Ictidomys tridecemlineatus	95.69	2.00e-113	401.00
IUUC-Lch-050353	Latimeria chalumnae	67.97	1.00e-74	273.00
IUUC-Laf-053406	Loxodonta africana	90.43	1.00e-103	369.00
IUUC-Meu-056129	Macropus eugenii	86.40	5.00e-106	377.00
IUUC-Mdo-062656	Monodelphis domestica	85.59	6.00e-105	373.00
IUUC-Mpu-066715	Mustela putorius furo	90.43	9.00e-102	362.00
IUUC-Nle-069403	Nomascus leucogenys	89.04	1.00e-99	355.00
IUUC-Ont-072022	Oreochromis niloticus	62.45	6.00e-68	250.00
IUUC-Oan-073355	Ornithorhynchus anatinus	77.06	6.00e-91	326.00
IUUC-Obr-076254	Oryza brachyantha	45.00	5.00e-08	51.20
IUUC-Oga-089067	Otolemur garnettii	90.83	4.00e-102	363.00
IUUC-Oar-089454	Ovis aries	76.75	5.00e-96	343.00
IUUC-Ptr-091405	Pan troglodytes	89.91	7.00e-100	356.00
IUUC-Pan-092634	Papio anubis	89.96	2.00e-100	358.00
IUUC-Psi-093940	Pelodiscus sinensis	72.29	2.00e-79	288.00
IUUC-Pfo-097180	Poecilia formosa	60.25	3.00e-63	234.00
IUUC-Pab-097837	Pongo abelii	89.91	7.00e-100	356.00
IUUC-Pva-102648	Pteropus vampyrus	95.22	1.00e-106	379.00
IUUC-Rno-106098	Rattus norvegicus	99.13	6.00e-117	413.00
IUUC-Sha-107548	Sarcophilus harrisii	85.96	3.00e-105	374.00
IUUC-Sly-111303	Solanum lycopersicum	44.29	1.00e-08	53.90
IUUC-Ssc-116419	Sus scrofa	90.35	1.00e-100	358.00
IUUC-Tru-118619	Takifugu rubripes	62.76	2.00e-70	258.00
IUUC-Tni-120889	Tetraodon nigroviridis	61.34	1.00e-69	256.00
IUUC-Ttr-128475	Tursiops truncatus	89.57	3.00e-101	361.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence