iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.90e-18	66.6	258	337

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk.....tcPvtrqplteedl.vPnltlrrliqawceenss 74
           +vpeefl+pI+le+M +P+ lpsG ++d+s++ek+  s        ++P+t+  +t++++  P+ +l++ i++++ ++s+
   Q: 258  DVPEEFLDPITLEIMPCPMLLPSGKVIDQSTLEKCNLSEAAwgrvpSDPFTGLAFTPQSQpLPHPSLKARIDRFLLQHSI 337
           69*********************************877777999***********999999****************987 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MVINLCLPQF RPRIHCNKVS ADGYEVENLI SEDLIKRSHG FRTEYFIRPP IYVTVSFPFN 60
VEICRVNIDL TAGGCQNVTG LELYTSALSS RAPQDAQDCW TTGLSETSVP DKEAFTLVGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTGTGGAG CGGTTGATGC GGGAGTCTGT ATATTGACTT ACCTGGTGCG GCCAGGGACT 60
GGAGTTAGGG CGCTACCCTC GTGGGTTTCA GGTGAGTGGA CGGCCGGAAA GGAGGTGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008979--Galactose-bd-like
IPR003613--Ubox_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51698--U_BOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF04564--U-box
PF14634--zf-RING_5

SMART

SM00504--Ubox

Gene Ontology

GO:0005925--C:focal adhesion
GO:0016604--C:nuclear body
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0000209--P:protein polyubiquitination

KEGG

rno:296161

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001702	Ailuropoda melanoleuca	81.15	0.00e+00	864.00
IUUC-Apl-003809	Anas platyrhynchos	58.14	1.00e-175	609.00
IUUC-Ame-011326	Astyanax mexicanus	33.10	1.00e-66	247.00
IUUC-Bta-012836	Bos taurus	71.72	0.00e+00	738.00
IUUC-Cja-018735	Callithrix jacchus	78.56	0.00e+00	840.00
IUUC-Cfa-020914	Canis familiaris	80.04	0.00e+00	848.00
IUUC-Cpo-022397	Cavia porcellus	75.42	0.00e+00	821.00
IUUC-Csa-023033	Chlorocebus sabaeus	79.24	0.00e+00	749.00
IUUC-Cho-025050	Choloepus hoffmanni	73.42	5.00e-127	447.00
IUUC-Cin-025271	Ciona intestinalis	24.72	1.00e-20	92.80
IUUC-Csv-025960	Ciona savignyi	28.08	2.00e-24	105.00
IUUC-Dre-028494	Danio rerio	33.45	1.00e-62	233.00
IUUC-Dno-029134	Dasypus novemcinctus	65.58	2.00e-151	528.00
IUUC-Dme-032212	Drosophila melanogaster	41.67	8.00e-27	115.00
IUUC-Eca-033535	Equus caballus	79.30	0.00e+00	838.00
IUUC-Fca-036298	Felis catus	80.33	0.00e+00	859.00
IUUC-Fal-037385	Ficedula albicollis	59.01	1.00e-169	589.00
IUUC-Gmo-039572	Gadus morhua	63.01	6.00e-22	99.00
IUUC-Gga-040207	Gallus gallus	57.93	5.00e-178	617.00
IUUC-Gac-042339	Gasterosteus aculeatus	40.36	4.00e-54	205.00
IUUC-Ggo-044710	Gorilla gorilla	79.48	0.00e+00	863.00
IUUC-Hsa-045766	Homo sapiens	79.11	0.00e+00	860.00
IUUC-Itr-048280	Ictidomys tridecemlineatus	79.85	0.00e+00	868.00
IUUC-Lch-050587	Latimeria chalumnae	45.96	2.00e-126	445.00
IUUC-Laf-053430	Loxodonta africana	72.83	0.00e+00	745.00
IUUC-Mcc-055661	Macaca mulatta	79.30	0.00e+00	862.00
IUUC-Meu-055959	Macropus eugenii	56.69	4.00e-162	564.00
IUUC-Mga-059505	Meleagris gallopavo	58.41	4.00e-178	617.00
IUUC-Mmr-061218	Microcebus murinus	79.67	0.00e+00	827.00
IUUC-Mdo-062113	Monodelphis domestica	63.41	0.00e+00	662.00
IUUC-Mmu-063349	Mus musculus	92.39	0.00e+00	970.00
IUUC-Mpu-066189	Mustela putorius furo	74.68	0.00e+00	746.00
IUUC-Mlu-067083	Myotis lucifugus	78.56	0.00e+00	856.00
IUUC-Nle-069481	Nomascus leucogenys	77.04	3.00e-112	399.00
IUUC-Opr-070674	Ochotona princeps	74.34	0.00e+00	782.00
IUUC-Ont-071995	Oreochromis niloticus	37.66	4.00e-79	288.00
IUUC-Oan-073003	Ornithorhynchus anatinus	60.56	6.00e-166	577.00
IUUC-Ocu-073834	Oryctolagus cuniculus	79.30	0.00e+00	827.00
IUUC-Ola-086469	Oryzias latipes	35.89	4.00e-72	265.00
IUUC-Oga-088316	Otolemur garnettii	77.54	0.00e+00	718.00
IUUC-Oar-089563	Ovis aries	77.57	0.00e+00	841.00
IUUC-Ptr-091293	Pan troglodytes	78.93	0.00e+00	858.00
IUUC-Pan-092705	Papio anubis	78.86	0.00e+00	859.00
IUUC-Psi-093111	Pelodiscus sinensis	61.00	0.00e+00	645.00
IUUC-Pfo-096603	Poecilia formosa	28.80	2.00e-32	134.00
IUUC-Pab-098636	Pongo abelii	76.94	0.00e+00	753.00
IUUC-Pca-100109	Procavia capensis	76.25	1.00e-128	452.00
IUUC-Pva-103028	Pteropus vampyrus	80.78	0.00e+00	835.00
IUUC-Sha-107133	Sarcophilus harrisii	55.21	6.00e-170	590.00
IUUC-Ssc-116252	Sus scrofa	73.43	0.00e+00	757.00
IUUC-Tgu-117163	Taeniopygia guttata	59.19	3.00e-173	601.00
IUUC-Tru-118541	Takifugu rubripes	36.09	3.00e-73	269.00
IUUC-Tsy-119281	Tarsius syrichta	71.94	3.00e-156	544.00
IUUC-Tni-120789	Tetraodon nigroviridis	36.96	2.00e-71	263.00
IUUC-Ttr-128555	Tursiops truncatus	79.67	0.00e+00	840.00
IUUC-Xtr-132303	Xenopus tropicalis	51.83	1.00e-151	529.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence