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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064182
Ensembl Protein ID ENSMUSP00000046732.8
UniProt Accession P59235; E9QPN3; NUP43_MOUSE
Genbank Protein ID BAC41049.1; ENSMUSP00000046732
Protein Name Nucleoporin Nup43; Nup107-160 subcomplex subunit Nup43
Genbank Nucleotide ID AK090019; AC156391
Gene Name Nup43
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000040034.15 ENSMUST00000040135.8 ENSMUSP00000046732.8
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarmiRNAMap
RAID2
Protein-protein Interaction
IIDHINTMentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.90e-17 62.0 260 298
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           H+++++ ++f  s+ ++l ++s Dg++  WD +t+ ++k
   Q: 260  HEAEMWEVHFhpSNpDHLFTCSEDGSLWHWDASTDAPEK 298
           99999******8778****************99988776 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation (By similarity).
 Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation (By similarity).
Protein Sequence
(Fasta)
MEEIYAKFVS QKISKTRWRP VPSGSLQTTE TFATGSWDNE ENCVSLWSIG DFGNLDSDGG 60
FEGDHQLLCD IRHHGDVMDL QFFDQERIVA ASSTGCVTVF LHHPNNQTLS VNQQWPAAHY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064182|E3,WD_repeat|Mus musculus
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Nucleotide Sequence
(Fasta)
GGGGCGGGCC TGAGGAGCGC GCAGTGTGCT TTCTGCTGAA CCTTCTTGCT GGTTTCAGCA 60
TGGAGGAAAT TTATGCTAAG TTCGTGTCTC AGAAAATTAG CAAAACCCGC TGGCGGCCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064182|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0131--Cell cycle
KW-0132--Cell division
KW-0137--Centromere
KW-0158--Chromosome
KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-0995--Kinetochore
KW-0498--Mitosis
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0000777--C:condensed chromosome kinetochore
GO:0031080--C:nuclear pore outer ring
GO:0051301--P:cell division
GO:0007059--P:chromosome segregation
GO:0007067--P:mitotic nuclear division
GO:0051028--P:mRNA transport
GO:0015031--P:protein transport
KEGG mmu:69912
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001593 Ailuropoda melanoleuca 92.89 0.00e+00 705.00
IUUC-Atr-002526 Amborella trichopoda 26.83 2.00e-10 60.10
IUUC-Apl-003533 Anas platyrhynchos 74.63 6.00e-140 489.00
IUUC-Aca-004965 Anolis carolinensis 70.26 5.00e-157 546.00
IUUC-Aly-006431 Arabidopsis lyrata 30.18 7.00e-14 71.60
IUUC-Ath-007253 Arabidopsis thaliana 30.36 8.00e-14 71.20
IUUC-Ame-011694 Astyanax mexicanus 63.24 2.00e-119 422.00
IUUC-Bta-013161 Bos taurus 92.11 0.00e+00 717.00
IUUC-Bdi-014758 Brachypodium distachyon 27.62 8.00e-11 61.20
IUUC-Bra-017838 Brassica rapa 27.27 1.00e-07 50.80
IUUC-Cel-018567 Caenorhabditis elegans 23.66 1.00e-08 54.30
IUUC-Cja-020000 Callithrix jacchus 81.14 4.00e-174 603.00
IUUC-Cfa-021112 Canis familiaris 93.16 0.00e+00 719.00
IUUC-Cpo-022095 Cavia porcellus 90.53 0.00e+00 696.00
IUUC-Csa-023460 Chlorocebus sabaeus 93.68 0.00e+00 719.00
IUUC-Cho-024279 Choloepus hoffmanni 91.47 2.00e-169 588.00
IUUC-Cin-025360 Ciona intestinalis 35.97 5.00e-61 228.00
IUUC-Csv-026301 Ciona savignyi 36.93 4.00e-53 201.00
IUUC-Dre-028097 Danio rerio 62.70 2.00e-134 472.00
IUUC-Dno-029131 Dasypus novemcinctus 91.32 0.00e+00 698.00
IUUC-Dor-030496 Dipodomys ordii 82.68 1.00e-178 619.00
IUUC-Dme-031834 Drosophila melanogaster 27.61 2.00e-40 159.00
IUUC-Ete-032448 Echinops telfairi 88.82 3.00e-158 551.00
IUUC-Eca-034409 Equus caballus 92.37 0.00e+00 717.00
IUUC-Eeu-035343 Erinaceus europaeus 77.11 5.00e-157 547.00
IUUC-Fca-036177 Felis catus 93.68 0.00e+00 724.00
IUUC-Fal-037657 Ficedula albicollis 68.95 1.00e-151 528.00
IUUC-Gmo-038946 Gadus morhua 65.96 2.00e-140 491.00
IUUC-Gga-041070 Gallus gallus 73.42 3.00e-159 554.00
IUUC-Gac-042442 Gasterosteus aculeatus 65.87 1.00e-144 505.00
IUUC-Gma-043812 Glycine max 25.54 1.00e-11 63.90
IUUC-Ggo-045223 Gorilla gorilla 93.42 0.00e+00 726.00
IUUC-Hsa-045956 Homo sapiens 93.68 0.00e+00 726.00
IUUC-Itr-048116 Ictidomys tridecemlineatus 95.28 0.00e+00 729.00
IUUC-Lch-050035 Latimeria chalumnae 70.63 2.00e-158 551.00
IUUC-Laf-053404 Loxodonta africana 88.68 0.00e+00 673.00
IUUC-Mcc-055813 Macaca mulatta 94.21 0.00e+00 723.00
IUUC-Meu-056388 Macropus eugenii 75.68 1.00e-159 555.00
IUUC-Mga-060193 Meleagris gallopavo 72.37 1.00e-166 578.00
IUUC-Mmr-060818 Microcebus murinus 93.16 0.00e+00 714.00
IUUC-Mdo-062822 Monodelphis domestica 88.95 0.00e+00 684.00
IUUC-Mpu-066865 Mustela putorius furo 94.12 0.00e+00 647.00
IUUC-Mlu-067329 Myotis lucifugus 92.11 0.00e+00 692.00
IUUC-Nle-069093 Nomascus leucogenys 94.21 0.00e+00 726.00
IUUC-Opr-070481 Ochotona princeps 83.99 0.00e+00 637.00
IUUC-Ont-072445 Oreochromis niloticus 66.67 6.00e-146 509.00
IUUC-Oan-073029 Ornithorhynchus anatinus 76.58 1.00e-168 585.00
IUUC-Ocu-074275 Oryctolagus cuniculus 91.58 0.00e+00 709.00
IUUC-Ola-086862 Oryzias latipes 63.23 9.00e-132 463.00
IUUC-Oga-088952 Otolemur garnettii 93.14 0.00e+00 717.00
IUUC-Oar-089300 Ovis aries 92.89 0.00e+00 722.00
IUUC-Ptr-091389 Pan troglodytes 93.95 0.00e+00 726.00
IUUC-Pan-092174 Papio anubis 93.95 0.00e+00 721.00
IUUC-Psi-093326 Pelodiscus sinensis 76.54 7.00e-158 549.00
IUUC-Pfo-096331 Poecilia formosa 65.15 1.00e-142 499.00
IUUC-Pab-098306 Pongo abelii 93.68 0.00e+00 724.00
IUUC-Pop-099166 Populus trichocarpa 31.91 2.00e-11 63.50
IUUC-Pca-100455 Procavia capensis 89.33 8.00e-72 264.00
IUUC-Ppe-101380 Prunus persica 29.78 3.00e-12 66.20
IUUC-Pva-102578 Pteropus vampyrus 93.16 0.00e+00 705.00
IUUC-Rno-105146 Rattus norvegicus 97.37 0.00e+00 713.00
IUUC-Sha-107640 Sarcophilus harrisii 89.24 0.00e+00 687.00
IUUC-Sar-113681 Sorex araneus 93.37 4.00e-108 384.00
IUUC-Sbi-113809 Sorghum bicolor 24.64 6.00e-05 42.00
IUUC-Ssc-116129 Sus scrofa 92.11 0.00e+00 709.00
IUUC-Tgu-117456 Taeniopygia guttata 67.14 2.00e-77 281.00
IUUC-Tru-117630 Takifugu rubripes 68.16 3.00e-99 354.00
IUUC-Tsy-119331 Tarsius syrichta 94.74 0.00e+00 730.00
IUUC-Tni-120077 Tetraodon nigroviridis 64.81 4.00e-136 477.00
IUUC-Tca-121814 Theobroma cacao 30.64 5.00e-10 58.90
IUUC-Tae-123605 Triticum aestivum 27.53 5.00e-10 58.50
IUUC-Tbe-127359 Tupaia belangeri 84.35 1.00e-178 619.00
IUUC-Ttr-128461 Tursiops truncatus 93.68 0.00e+00 715.00
IUUC-Vpa-130162 Vicugna pacos 94.21 0.00e+00 715.00
IUUC-Vvi-131114 Vitis vinifera 28.18 8.00e-11 61.20
IUUC-Xtr-132446 Xenopus tropicalis 68.34 7.00e-153 533.00
Created Date 25-Jun-2017

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