iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-45	151.0	170	206
UBD/Beta-Prp	2.20e-63	214.3	173	460

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c+a  ++   +++G++D +ik+WDl +g+l
   Q: 170  GHLGWVRCIAVePGnEWFATGAGDRVIKIWDLASGKL 206
           8***********77799***************99987 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdk 108
           + ++c+++ p+++++atg  d+ ik+wd+ +gkl  sl gh ++v+ v  s + ++l +++eDr +k wdl+ +k +++++gh + v+sl+++p+ d+
   Q: 173  GWVRCIAVEPGNEWFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDV 270
           56899********************************************************************************************* PP
   S: 109  lvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvkl 206
           l++ ++d+t+r+wd++t+  ++ tl+gh+ +v +vv + ++  +++Gs D+tvrlWdl+ gk + tlt  h++sv+s+ ++++   ++s+s d+ +k 
   Q: 271  LATSGRDSTARIWDMRTKANVH-TLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTN-HKKSVRSIVLHPSLYMFASASPDN-IKQ 365
           **********************.********************************************97.************999999999986.*** PP
   S: 207  wdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn.......ssvisvavlsfgdnvlvlgsedskvniwklk 295
           w + +g+ v+   ght+ v+++++   +  lvsg++ g+ ++Wd r+g + + +q +        +  i   +++ +++ l+++++d++++++k +
   Q: 366  WRCPEGKFVQNISGHTSIVNCMAAN-SEGVLVSGGDNGTMFFWDWRTGYNFQRFQAPVqpgsmdsEAGIFAMCFDQSGSRLITAEADKTIKVYKED 460
           *************************.999****************************99*99964334444446777****************975 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MAMEDVQKHS VHTLIFRSLK RTHDLFVSNQ GNLPEIDERL EKLRRSIKAK DGYGLVLDKV 60
AKIGEARKAS GAQTPGDKTL AITDGSATDA ASGAGSLVKY NAGARPAEKT APLVTGTHTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGATTGT TATGTATGGC TTGTGGTGGT CAGCTGCAAG AGCCGCGCCG CGTTTTTAAC 60
AAATTTAGCG AATAAGCAAT AAATAACAGA CAATGGCCAT GGAAGACGTG CAGAAGCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0007030--P:Golgi organization
GO:0000398--P:mRNA splicing, via spliceosome
GO:0009306--P:protein secretion

KEGG

dme:Dmel_CG1796

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	49.90	8.00e-132	462.00
IUUC-Aml-001605	Ailuropoda melanoleuca	58.87	4.00e-178	616.00
IUUC-Atr-002757	Amborella trichopoda	48.04	4.00e-128	450.00
IUUC-Apl-003198	Anas platyrhynchos	58.45	6.00e-178	616.00
IUUC-Aca-004683	Anolis carolinensis	57.95	1.00e-177	615.00
IUUC-Aly-005775	Arabidopsis lyrata	49.34	4.00e-132	464.00
IUUC-Ath-007460	Arabidopsis thaliana	49.46	6.00e-132	463.00
IUUC-Ago-007884	Ashbya gossypii	48.94	3.00e-104	370.00
IUUC-Acl-008153	Aspergillus clavatus	66.56	2.00e-133	468.00
IUUC-Afl-008384	Aspergillus flavus	67.18	2.00e-135	474.00
IUUC-Afu-009045	Aspergillus fumigatus	65.95	2.00e-133	468.00
IUUC-Ani-009229	Aspergillus nidulans	65.23	6.00e-133	466.00
IUUC-Ang-009812	Aspergillus niger	66.35	1.00e-126	444.00
IUUC-Aor-010059	Aspergillus oryzae	67.18	2.00e-135	474.00
IUUC-Ate-010351	Aspergillus terreus	66.87	4.00e-140	490.00
IUUC-Ame-011613	Astyanax mexicanus	48.27	5.00e-98	350.00
IUUC-Bgr-012042	Blumeria graminis	50.41	7.00e-140	489.00
IUUC-Bta-012406	Bos taurus	59.77	2.00e-179	620.00
IUUC-Bci-013760	Botrytis cinerea	61.73	5.00e-136	476.00
IUUC-Bdi-014776	Brachypodium distachyon	64.63	2.00e-133	468.00
IUUC-Bol-016189	Brassica oleracea	49.24	1.00e-134	472.00
IUUC-Bra-018044	Brassica rapa	49.03	7.00e-134	469.00
IUUC-Cel-018651	Caenorhabditis elegans	56.40	1.00e-166	578.00
IUUC-Cja-019974	Callithrix jacchus	59.15	5.00e-179	619.00
IUUC-Cfa-021085	Canis familiaris	59.14	2.00e-178	618.00
IUUC-Cpo-021458	Cavia porcellus	59.77	4.00e-179	620.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	61.30	1.00e-127	448.00
IUUC-Csa-023883	Chlorocebus sabaeus	59.92	5.00e-179	619.00
IUUC-Cho-024623	Choloepus hoffmanni	58.78	2.00e-169	587.00
IUUC-Cin-025190	Ciona intestinalis	57.50	7.00e-173	599.00
IUUC-Csv-026367	Ciona savignyi	56.67	5.00e-176	609.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	64.72	2.00e-140	491.00
IUUC-Cne-027069	Cryptococcus neoformans	59.57	2.00e-132	464.00
IUUC-Cme-027233	Cyanidioschyzon merolae	29.31	3.00e-34	138.00
IUUC-Dre-028260	Danio rerio	60.12	4.00e-179	620.00
IUUC-Dno-029112	Dasypus novemcinctus	60.66	2.00e-179	620.00
IUUC-Dor-031118	Dipodomys ordii	75.74	3.00e-165	573.00
IUUC-Dse-031493	Dothistroma septosporum	60.48	3.00e-134	471.00
IUUC-Ete-032411	Echinops telfairi	52.16	5.00e-141	493.00
IUUC-Eca-033521	Equus caballus	59.88	7.00e-179	619.00
IUUC-Eeu-035249	Erinaceus europaeus	64.79	2.00e-134	471.00
IUUC-Fca-036358	Felis catus	59.42	2.00e-178	617.00
IUUC-Fal-036933	Ficedula albicollis	59.42	5.00e-180	623.00
IUUC-Fox-037713	Fusarium oxysporum	59.95	8.00e-144	502.00
IUUC-Fso-038380	Fusarium solani	66.06	3.00e-143	500.00
IUUC-Gmo-039133	Gadus morhua	60.24	1.00e-177	615.00
IUUC-Ggr-039915	Gaeumannomyces graminis	65.35	2.00e-134	471.00
IUUC-Gga-041176	Gallus gallus	58.72	2.00e-178	617.00
IUUC-Gac-042344	Gasterosteus aculeatus	60.86	3.00e-177	613.00
IUUC-Gma-042892	Glycine max	52.16	5.00e-138	483.00
IUUC-Ggo-044478	Gorilla gorilla	59.88	8.00e-178	615.00
IUUC-Hsa-046037	Homo sapiens	59.92	2.00e-178	618.00
IUUC-Hvu-047349	Hordeum vulgare	53.48	2.00e-135	474.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	59.61	3.00e-178	617.00
IUUC-Kpa-049343	Komagataella pastoris	57.23	6.00e-117	413.00
IUUC-Lch-049830	Latimeria chalumnae	58.91	2.00e-178	617.00
IUUC-Lpe-051442	Leersia perrieri	52.27	3.00e-134	471.00
IUUC-Loc-051794	Lepisosteus oculatus	58.88	3.00e-167	580.00
IUUC-Lma-053137	Leptosphaeria maculans	57.40	8.00e-127	446.00
IUUC-Laf-053471	Loxodonta africana	59.42	2.00e-178	618.00
IUUC-Mcc-055627	Macaca mulatta	59.92	2.00e-179	620.00
IUUC-Meu-056148	Macropus eugenii	60.58	2.00e-172	597.00
IUUC-Mor-056960	Magnaporthe oryzae	66.16	2.00e-141	494.00
IUUC-Mtr-057816	Medicago truncatula	50.72	4.00e-136	476.00
IUUC-Mla-059031	Melampsora laricipopulina	62.65	2.00e-129	454.00
IUUC-Mga-059337	Meleagris gallopavo	57.88	2.00e-177	614.00
IUUC-Mvi-060217	Microbotryum violaceum	62.46	2.00e-132	464.00
IUUC-Mmr-061018	Microcebus murinus	59.88	7.00e-179	619.00
IUUC-Mdo-062863	Monodelphis domestica	57.73	9.00e-173	598.00
IUUC-Mmu-063988	Mus musculus	59.65	3.00e-179	620.00
IUUC-Mac-064459	Musa acuminata	50.86	6.00e-127	446.00
IUUC-Mpu-066559	Mustela putorius furo	60.08	3.00e-179	620.00
IUUC-Mlu-067361	Myotis lucifugus	59.68	5.00e-178	616.00
IUUC-Nfi-068492	Neosartorya fischeri	66.26	9.00e-134	469.00
IUUC-Ncr-068808	Neurospora crassa	64.22	5.00e-139	486.00
IUUC-Nle-069875	Nomascus leucogenys	59.85	1.00e-178	618.00
IUUC-Opr-070462	Ochotona princeps	77.82	3.00e-128	451.00
IUUC-Ont-071365	Oreochromis niloticus	60.54	3.00e-178	617.00
IUUC-Oan-072708	Ornithorhynchus anatinus	59.03	2.00e-179	621.00
IUUC-Ocu-074594	Oryctolagus cuniculus	59.85	4.00e-178	616.00
IUUC-Oba-075570	Oryza barthii	50.54	1.00e-132	465.00
IUUC-Obr-076366	Oryza brachyantha	63.16	8.00e-95	338.00
IUUC-Ogl-077153	Oryza glaberrima	50.54	8.00e-132	462.00
IUUC-Ogu-078540	Oryza glumaepatula	50.54	2.00e-132	465.00
IUUC-Oin-079612	Oryza indica	50.00	1.00e-130	459.00
IUUC-Olo-081077	Oryza longistaminata	50.00	1.00e-130	459.00
IUUC-Ome-081236	Oryza meridionalis	63.66	9.00e-131	459.00
IUUC-Oni-082499	Oryza nivara	50.54	2.00e-132	465.00
IUUC-Opu-083499	Oryza punctata	63.36	1.00e-130	458.00
IUUC-Oru-084276	Oryza rufipogon	50.54	2.00e-132	465.00
IUUC-Osa-085849	Oryza sativa	50.54	2.00e-132	465.00
IUUC-Ola-086655	Oryzias latipes	59.57	2.00e-175	607.00
IUUC-Olu-087637	Ostreococcus lucimarinus	59.60	7.00e-126	442.00
IUUC-Oga-087934	Otolemur garnettii	59.50	2.00e-178	617.00
IUUC-Oar-090185	Ovis aries	60.43	1.00e-179	622.00
IUUC-Ptr-091198	Pan troglodytes	59.85	1.00e-178	618.00
IUUC-Pan-092622	Papio anubis	59.92	5.00e-179	619.00
IUUC-Psi-093320	Pelodiscus sinensis	58.61	5.00e-178	616.00
IUUC-Pma-094638	Petromyzon marinus	61.39	0.00e+00	627.00
IUUC-Pno-094826	Phaeosphaeria nodorum	51.18	2.00e-107	381.00
IUUC-Ppa-095576	Physcomitrella patens	65.51	7.00e-132	462.00
IUUC-Pfo-096894	Poecilia formosa	60.43	2.00e-178	617.00
IUUC-Pab-098020	Pongo abelii	59.85	1.00e-178	618.00
IUUC-Pop-099180	Populus trichocarpa	47.94	4.00e-131	460.00
IUUC-Pca-100909	Procavia capensis	57.05	4.00e-138	483.00
IUUC-Ppe-101346	Prunus persica	49.28	1.00e-132	465.00
IUUC-Pva-102167	Pteropus vampyrus	65.42	7.00e-139	486.00
IUUC-Pgr-103516	Puccinia graminis	52.80	8.00e-134	469.00
IUUC-Ptt-103738	Puccinia triticina	53.11	3.00e-133	467.00
IUUC-Pte-104352	Pyrenophora teres	57.69	6.00e-130	456.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	57.69	8.00e-130	456.00
IUUC-Rno-105291	Rattus norvegicus	59.34	4.00e-178	616.00
IUUC-Sce-106204	Saccharomyces cerevisiae	51.06	3.00e-105	374.00
IUUC-Sha-106943	Sarcophilus harrisii	57.28	2.00e-169	587.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	65.71	5.00e-131	459.00
IUUC-Spo-108049	Schizosaccharomyces pombe	52.32	1.00e-136	478.00
IUUC-Smo-109043	Selaginella moellendorffii	63.80	9.00e-134	468.00
IUUC-Sit-110431	Setaria italica	52.58	3.00e-135	474.00
IUUC-Sly-111391	Solanum lycopersicum	50.98	5.00e-125	440.00
IUUC-Stu-112364	Solanum tuberosum	56.25	3.00e-100	357.00
IUUC-Sar-113450	Sorex araneus	76.04	6.00e-165	572.00
IUUC-Sbi-113829	Sorghum bicolor	51.40	7.00e-136	476.00
IUUC-Sre-115153	Sporisorium reilianum	66.14	2.00e-127	448.00
IUUC-Ssc-116274	Sus scrofa	59.53	1.00e-179	621.00
IUUC-Tgu-117417	Taeniopygia guttata	59.26	2.00e-179	621.00
IUUC-Tru-117615	Takifugu rubripes	60.63	2.00e-171	594.00
IUUC-Tsy-119480	Tarsius syrichta	59.38	2.00e-177	614.00
IUUC-Tni-119847	Tetraodon nigroviridis	60.78	8.00e-179	619.00
IUUC-Tca-121287	Theobroma cacao	49.39	4.00e-134	470.00
IUUC-Tre-122010	Trichoderma reesei	64.81	3.00e-144	503.00
IUUC-Tvi-122475	Trichoderma virens	59.38	2.00e-143	501.00
IUUC-Tae-124921	Triticum aestivum	53.48	1.00e-135	475.00
IUUC-Tur-126116	Triticum urartu	45.80	3.00e-102	364.00
IUUC-Tme-126992	Tuber melanosporum	66.56	1.00e-139	489.00
IUUC-Tbe-127803	Tupaia belangeri	77.56	3.00e-123	434.00
IUUC-Ttr-128933	Tursiops truncatus	59.30	2.00e-178	618.00
IUUC-Uma-129447	Ustilago maydis	65.15	8.00e-125	439.00
IUUC-Vda-129780	Verticillium dahliae	64.72	6.00e-139	486.00
IUUC-Vpa-130557	Vicugna pacos	55.72	2.00e-63	235.00
IUUC-Vvi-130918	Vitis vinifera	47.50	7.00e-127	446.00
IUUC-Xtr-132409	Xenopus tropicalis	73.16	1.00e-164	572.00
IUUC-Xma-133420	Xiphophorus maculatus	61.49	0.00e+00	627.00
IUUC-Yli-134362	Yarrowia lipolytica	56.62	3.00e-118	417.00
IUUC-Zma-135804	Zea mays	51.07	1.00e-132	465.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence