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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Rno-105248
UUCD1 version UUC-RaN-00820
Ensembl Protein ID ENSRNOP00000025133.5
UniProt Accession Q562C2; BOP1_RAT
Genbank Protein ID AAH92594.1
Protein Name Ribosome biogenesis protein BOP1; Block of proliferation 1 protein
Genbank Nucleotide ID BC092594
Gene Name Bop1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000021773.5 ENSRNOT00000025134.5 ENSRNOP00000025133.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACmiRNAMapRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusUniProt
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 8.80e-21 73.5 396 435
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
    gH+d v+cl+ ++ l+sGsdDgt+++W++ t ++ k+
   Q: 396 GHSDLVRCLSVsPGgQWLASGSDDGTLRLWEVATARCMKT 435
    8**********988899*******************9875 PP
   

Organism Rattus norvegicus
Functional Description
(View)

Functional Description



     Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Sequence
(Fasta)
MAGACGKHHM SPGSLPGKRR LEPDQEPQIQ EPLLLSDPDS SLSDSEESVF SGLEDSGSDT 60
SDEDTEEVAR AGCDKDNRTE KTSEEQEQAV PPCPRAEEAG ALTRDEYEED SSDEEDIRNT 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Rno-105248|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTGCAGCATG GCGGGGGCGT GTGGTAAGCA CCACATGTCA CCGGGATCGC TGCCAGGGAA 60
ACGGCGTTTG GAACCTGATC AGGAGCCACA GATACAAGAG GTAACTTCGA GGTAGCGGGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Rno-105248|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR028598--BOP1/Erb1
IPR012953--BOP1_N_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08145--BOP1NT
PF00400--WD40

SMART

SM01035--BOP1NT
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0003723--F:RNA binding
GO:0008283--P:cell proliferation
GO:0000448--P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0051726--P:regulation of cell cycle

KEGG rno:300050
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001158 Aegilops tauschii 41.58 2.00e-124 439.00
IUUC-Aml-001507 Ailuropoda melanoleuca 80.78 0.00e+00 1042.00
IUUC-Atr-003141 Amborella trichopoda 42.02 9.00e-88 317.00
IUUC-Apl-003545 Anas platyrhynchos 67.13 0.00e+00 806.00
IUUC-Aly-005649 Arabidopsis lyrata 45.02 2.00e-157 549.00
IUUC-Ath-007625 Arabidopsis thaliana 45.28 1.00e-155 543.00
IUUC-Ago-007958 Ashbya gossypii 43.97 2.00e-163 569.00
IUUC-Acl-008344 Aspergillus clavatus 43.72 1.00e-143 503.00
IUUC-Afl-008616 Aspergillus flavus 43.26 1.00e-146 513.00
IUUC-Afu-009083 Aspergillus fumigatus 44.50 6.00e-142 498.00
IUUC-Ani-009365 Aspergillus nidulans 43.57 5.00e-145 508.00
IUUC-Ang-009796 Aspergillus niger 43.57 1.00e-142 500.00
IUUC-Aor-010015 Aspergillus oryzae 43.26 1.00e-146 513.00
IUUC-Ate-010537 Aspergillus terreus 44.72 1.00e-149 523.00
IUUC-Ame-011767 Astyanax mexicanus 68.80 2.00e-114 404.00
IUUC-Bgr-012286 Blumeria graminis 42.86 1.00e-149 523.00
IUUC-Bta-013569 Bos taurus 83.80 0.00e+00 1103.00
IUUC-Bci-013820 Botrytis cinerea 42.25 9.00e-141 494.00
IUUC-Bdi-014895 Brachypodium distachyon 45.78 7.00e-155 540.00
IUUC-Bol-016099 Brassica oleracea 45.31 3.00e-159 555.00
IUUC-Bra-017174 Brassica rapa 45.15 6.00e-159 555.00
IUUC-Cel-018201 Caenorhabditis elegans 47.19 7.00e-158 550.00
IUUC-Cja-019009 Callithrix jacchus 76.30 0.00e+00 952.00
IUUC-Cfa-020173 Canis familiaris 81.29 0.00e+00 1015.00
IUUC-Cpo-021796 Cavia porcellus 88.18 0.00e+00 1105.00
IUUC-Cre-022650 Chlamydomonas reinhardtii 47.93 3.00e-154 538.00
IUUC-Csa-023440 Chlorocebus sabaeus 88.50 0.00e+00 1154.00
IUUC-Cin-025782 Ciona intestinalis 55.61 0.00e+00 754.00
IUUC-Csv-026352 Ciona savignyi 56.57 0.00e+00 739.00
IUUC-Cgl-026393 Colletotrichum gloeosporioides 39.37 1.00e-115 410.00
IUUC-Cne-027004 Cryptococcus neoformans 45.38 3.00e-170 592.00
IUUC-Cme-027242 Cyanidioschyzon merolae 39.18 4.00e-124 438.00
IUUC-Dre-028658 Danio rerio 73.54 0.00e+00 984.00
IUUC-Dno-028883 Dasypus novemcinctus 81.38 0.00e+00 1070.00
IUUC-Dor-031031 Dipodomys ordii 88.19 0.00e+00 1132.00
IUUC-Dse-031443 Dothistroma septosporum 40.40 5.00e-144 504.00
IUUC-Dme-031786 Drosophila melanogaster 53.10 0.00e+00 725.00
IUUC-Eca-033677 Equus caballus 86.28 0.00e+00 1129.00
IUUC-Eeu-035310 Erinaceus europaeus 84.66 0.00e+00 914.00
IUUC-Fca-035888 Felis catus 84.50 0.00e+00 1080.00
IUUC-Fal-037438 Ficedula albicollis 67.96 0.00e+00 741.00
IUUC-Fox-037973 Fusarium oxysporum 44.87 3.00e-158 552.00
IUUC-Fso-038187 Fusarium solani 44.71 6.00e-158 551.00
IUUC-Gmo-039114 Gadus morhua 65.15 0.00e+00 837.00
IUUC-Ggr-039746 Gaeumannomyces graminis 42.75 2.00e-153 536.00
IUUC-Gga-040631 Gallus gallus 73.45 1.00e-158 552.00
IUUC-Gac-042582 Gasterosteus aculeatus 65.89 0.00e+00 882.00
IUUC-Gma-044215 Glycine max 45.06 2.00e-149 522.00
IUUC-Ggo-045587 Gorilla gorilla 90.08 0.00e+00 1137.00
IUUC-Hsa-046319 Homo sapiens 88.80 0.00e+00 1159.00
IUUC-Hvu-047526 Hordeum vulgare 45.31 1.00e-147 516.00
IUUC-Itr-048683 Ictidomys tridecemlineatus 87.99 0.00e+00 1136.00
IUUC-Kpa-049221 Komagataella pastoris 43.38 3.00e-154 539.00
IUUC-Lch-049640 Latimeria chalumnae 74.47 0.00e+00 1005.00
IUUC-Lpe-051135 Leersia perrieri 43.02 5.00e-136 478.00
IUUC-Loc-051930 Lepisosteus oculatus 73.33 0.00e+00 987.00
IUUC-Lma-053290 Leptosphaeria maculans 41.25 2.00e-145 509.00
IUUC-Laf-053903 Loxodonta africana 70.20 0.00e+00 967.00
IUUC-Mcc-055471 Macaca mulatta 88.04 0.00e+00 1147.00
IUUC-Meu-056190 Macropus eugenii 82.76 0.00e+00 1045.00
IUUC-Mor-057135 Magnaporthe oryzae 42.50 2.00e-145 509.00
IUUC-Mpo-057475 Magnaporthe poae 42.68 5.00e-142 498.00
IUUC-Mtr-058689 Medicago truncatula 41.52 7.00e-134 471.00
IUUC-Mla-059149 Melampsora laricipopulina 45.85 8.00e-169 587.00
IUUC-Mga-059645 Meleagris gallopavo 63.52 1.00e-99 355.00
IUUC-Mvi-060485 Microbotryum violaceum 45.78 6.00e-147 515.00
IUUC-Mmr-061674 Microcebus murinus 88.46 0.00e+00 1090.00
IUUC-Mdo-062973 Monodelphis domestica 81.63 0.00e+00 1061.00
IUUC-Mmu-064180 Mus musculus 93.72 0.00e+00 1288.00
IUUC-Mac-064535 Musa acuminata 42.33 4.00e-98 352.00
IUUC-Mpu-066406 Mustela putorius furo 86.22 0.00e+00 1122.00
IUUC-Mlu-067795 Myotis lucifugus 88.05 0.00e+00 1106.00
IUUC-Nfi-068516 Neosartorya fischeri 44.19 4.00e-134 472.00
IUUC-Ncr-068767 Neurospora crassa 43.71 2.00e-139 489.00
IUUC-Opr-071084 Ochotona princeps 85.00 6.00e-142 496.00
IUUC-Ont-071614 Oreochromis niloticus 68.66 0.00e+00 919.00
IUUC-Oba-075980 Oryza barthii 43.00 4.00e-136 478.00
IUUC-Obr-076799 Oryza brachyantha 45.53 4.00e-151 528.00
IUUC-Ogl-077134 Oryza glaberrima 45.06 4.00e-145 508.00
IUUC-Ogu-078655 Oryza glumaepatula 43.76 2.00e-140 493.00
IUUC-Oin-079654 Oryza indica 45.06 7.00e-145 507.00
IUUC-Olo-080706 Oryza longistaminata 42.83 4.00e-137 481.00
IUUC-Ome-081716 Oryza meridionalis 39.06 1.00e-116 414.00
IUUC-Oni-082508 Oryza nivara 43.85 6.00e-138 484.00
IUUC-Opu-083707 Oryza punctata 42.83 4.00e-136 478.00
IUUC-Oru-084453 Oryza rufipogon 42.83 4.00e-137 481.00
IUUC-Osa-085811 Oryza sativa 45.06 4.00e-145 508.00
IUUC-Ola-087361 Oryzias latipes 69.52 0.00e+00 917.00
IUUC-Oga-088015 Otolemur garnettii 87.29 0.00e+00 1145.00
IUUC-Oar-090058 Ovis aries 90.48 3.00e-88 318.00
IUUC-Ptr-090631 Pan troglodytes 81.05 4.00e-138 484.00
IUUC-Pan-092306 Papio anubis 88.21 0.00e+00 1147.00
IUUC-Pma-094622 Petromyzon marinus 71.87 0.00e+00 966.00
IUUC-Pno-094794 Phaeosphaeria nodorum 39.87 2.00e-134 472.00
IUUC-Ppa-095528 Physcomitrella patens 43.76 1.00e-96 347.00
IUUC-Pfo-096682 Poecilia formosa 69.19 0.00e+00 927.00
IUUC-Pab-097939 Pongo abelii 88.99 0.00e+00 1022.00
IUUC-Pop-099530 Populus trichocarpa 46.03 5.00e-142 498.00
IUUC-Pca-100333 Procavia capensis 84.32 0.00e+00 1092.00
IUUC-Ppe-102078 Prunus persica 44.73 6.00e-152 531.00
IUUC-Pgr-103525 Puccinia graminis 46.18 1.00e-162 566.00
IUUC-Ptt-103929 Puccinia triticina 45.78 9.00e-158 551.00
IUUC-Pte-104029 Pyrenophora teres 42.81 4.00e-154 538.00
IUUC-Pyt-104446 Pyrenophora triticirepentis 42.97 3.00e-154 538.00
IUUC-Sce-106381 Saccharomyces cerevisiae 41.55 1.00e-155 543.00
IUUC-Sha-106519 Sarcophilus harrisii 82.93 0.00e+00 1065.00
IUUC-Sja-107908 Schizosaccharomyces japonicus 41.86 2.00e-142 499.00
IUUC-Spo-108071 Schizosaccharomyces pombe 42.50 1.00e-139 490.00
IUUC-Smo-109604 Selaginella moellendorffii 46.93 3.00e-157 548.00
IUUC-Sit-110551 Setaria italica 44.88 5.00e-148 518.00
IUUC-Sly-110970 Solanum lycopersicum 47.23 6.00e-84 304.00
IUUC-Stu-112593 Solanum tuberosum 45.87 2.00e-156 546.00
IUUC-Sar-113123 Sorex araneus 85.40 9.00e-149 519.00
IUUC-Sbi-113945 Sorghum bicolor 44.07 2.00e-151 529.00
IUUC-Sre-115188 Sporisorium reilianum 44.65 8.00e-159 554.00
IUUC-Ssc-115352 Sus scrofa 88.29 0.00e+00 1081.00
IUUC-Tru-117685 Takifugu rubripes 70.23 0.00e+00 934.00
IUUC-Tni-119982 Tetraodon nigroviridis 69.94 0.00e+00 900.00
IUUC-Tca-121664 Theobroma cacao 46.19 1.00e-158 553.00
IUUC-Tre-122229 Trichoderma reesei 44.01 6.00e-140 491.00
IUUC-Tvi-122576 Trichoderma virens 44.11 6.00e-143 501.00
IUUC-Tae-124110 Triticum aestivum 44.61 8.00e-138 484.00
IUUC-Tur-126781 Triticum urartu 41.91 5.00e-121 428.00
IUUC-Tme-127080 Tuber melanosporum 46.81 9.00e-172 597.00
IUUC-Ttr-128514 Tursiops truncatus 83.48 0.00e+00 777.00
IUUC-Uma-129556 Ustilago maydis 43.81 6.00e-154 538.00
IUUC-Vda-129715 Verticillium dahliae 44.32 2.00e-152 532.00
IUUC-Vvi-131211 Vitis vinifera 44.78 2.00e-148 519.00
IUUC-Xma-133883 Xiphophorus maculatus 69.14 0.00e+00 892.00
IUUC-Yli-134438 Yarrowia lipolytica 43.71 2.00e-145 509.00
IUUC-Zma-135341 Zea mays 35.49 1.00e-88 321.00
Created Date 25-Jun-2017

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