iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.50e-66	223.1	16	204

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesitelee 102
           YDRQirlwG++aq++++sakvll+++g++G+E+ K++vl+G+g++t++D++ v+ ++l+ qF++  edvg+ K ++++e++++lnp +++ +++++++e++e
   Q: 16   YDRQIRLWGMTAQANMRSAKVLLINLGAIGSEITKSIVLSGIGHLTILDGHMVTEEDLGSQFFIGSEDVGQWKIDATKERIQDLNPRIELNFDKQDLQEKDE 117
           ****************************************************************************************************** PP
   S: 103  eivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.......vlfnkll 197
           e  Ff++fd+Vv++ +++++  k+n+l++++++pl+ +g+ Gl+ +v                       f +l+e+++++e+            +      
   Q: 118  E--FFQQFDLVVATEMQIDEAIKINTLTRKLNIPLYVAGSNGLFAYV-----------------------FIDLIEFISEDEKLQSVRpttvgpiS------ 188
           *..********************************************.......................99999999988877664433233221...... PP
   S: 198  eeeageeevlekldsee 214
             +++  ev+ ++d+e+
   Q: 189  -SNRSIIEVTTRKDEED 204
           .2333333333333222 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Present with 7430 molecules/cell in log phase SD medium.

Protein Sequence
(Fasta)

MDMKVEKLSE DEIALYDRQI RLWGMTAQAN MRSAKVLLIN LGAIGSEITK SIVLSGIGHL 60
TILDGHMVTE EDLGSQFFIG SEDVGQWKID ATKERIQDLN PRIELNFDKQ DLQEKDEEFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATATGA AAGTAGAAAA ATTAAGTGAA GATGAAATTG CACTGTATGA TAGACAGATT 60
CGTCTATGGG GAATGACAGC ACAGGCCAAT ATGAGATCAG CAAAAGTATT GCTGATCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-1017--Isopeptide bond
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0031510--C:SUMO activating enzyme complex
GO:0008641--F:small protein activating enzyme activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0016925--P:protein sumoylation

KEGG

sce:YPR180W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001477	Ailuropoda melanoleuca	32.13	2.00e-44	171.00
IUUC-Aca-004868	Anolis carolinensis	30.42	2.00e-40	157.00
IUUC-Ago-007891	Ashbya gossypii	47.09	9.00e-78	281.00
IUUC-Acl-008197	Aspergillus clavatus	38.86	4.00e-62	229.00
IUUC-Afl-008520	Aspergillus flavus	37.71	9.00e-64	235.00
IUUC-Afu-009107	Aspergillus fumigatus	36.39	8.00e-56	208.00
IUUC-Ani-009143	Aspergillus nidulans	35.65	4.00e-58	216.00
IUUC-Ang-009804	Aspergillus niger	38.86	3.00e-67	246.00
IUUC-Aor-010190	Aspergillus oryzae	37.71	9.00e-64	235.00
IUUC-Ate-010519	Aspergillus terreus	31.43	2.00e-31	127.00
IUUC-Ame-011043	Astyanax mexicanus	31.93	2.00e-35	140.00
IUUC-Bgr-012084	Blumeria graminis	37.82	3.00e-61	227.00
IUUC-Bta-012723	Bos taurus	32.13	7.00e-44	169.00
IUUC-Bci-013809	Botrytis cinerea	38.40	3.00e-67	246.00
IUUC-Bdi-014800	Brachypodium distachyon	24.57	5.00e-28	116.00
IUUC-Cja-019815	Callithrix jacchus	33.72	6.00e-49	185.00
IUUC-Cfa-020329	Canis familiaris	32.13	2.00e-44	170.00
IUUC-Cpo-022208	Cavia porcellus	32.28	1.00e-45	175.00
IUUC-Csa-023592	Chlorocebus sabaeus	31.94	2.00e-36	143.00
IUUC-Cho-024345	Choloepus hoffmanni	26.64	5.00e-16	75.90
IUUC-Cin-025351	Ciona intestinalis	31.70	2.00e-40	157.00
IUUC-Cgl-026491	Colletotrichum gloeosporioides	37.04	4.00e-62	229.00
IUUC-Cne-026970	Cryptococcus neoformans	39.04	5.00e-22	96.30
IUUC-Cme-027210	Cyanidioschyzon merolae	25.62	3.00e-12	64.70
IUUC-Dre-028263	Danio rerio	30.97	6.00e-35	139.00
IUUC-Dno-030055	Dasypus novemcinctus	32.43	1.00e-44	171.00
IUUC-Dor-030864	Dipodomys ordii	31.13	8.00e-39	152.00
IUUC-Dse-031565	Dothistroma septosporum	37.03	2.00e-59	221.00
IUUC-Dme-032011	Drosophila melanogaster	40.62	2.00e-33	133.00
IUUC-Ete-032982	Echinops telfairi	30.32	2.00e-38	150.00
IUUC-Eca-034164	Equus caballus	30.00	9.00e-37	145.00
IUUC-Eeu-034713	Erinaceus europaeus	45.65	3.00e-19	88.20
IUUC-Fca-035564	Felis catus	32.13	1.00e-44	171.00
IUUC-Fox-037928	Fusarium oxysporum	38.75	3.00e-64	237.00
IUUC-Fso-038404	Fusarium solani	39.47	5.00e-65	239.00
IUUC-Gmo-038867	Gadus morhua	31.38	3.00e-35	140.00
IUUC-Ggr-040068	Gaeumannomyces graminis	38.03	6.00e-64	236.00
IUUC-Gga-041197	Gallus gallus	31.82	4.00e-30	123.00
IUUC-Gac-042609	Gasterosteus aculeatus	31.45	7.00e-38	149.00
IUUC-Ggo-044600	Gorilla gorilla	33.63	1.00e-47	181.00
IUUC-Hsa-046731	Homo sapiens	33.63	1.00e-47	181.00
IUUC-Itr-049038	Ictidomys tridecemlineatus	33.33	2.00e-46	177.00
IUUC-Kpa-049371	Komagataella pastoris	36.63	3.00e-60	223.00
IUUC-Lch-050045	Latimeria chalumnae	32.73	1.00e-43	168.00
IUUC-Lpe-051103	Leersia perrieri	24.78	3.00e-30	124.00
IUUC-Loc-051749	Lepisosteus oculatus	27.01	1.00e-24	105.00
IUUC-Lma-053150	Leptosphaeria maculans	36.52	1.00e-64	238.00
IUUC-Laf-053875	Loxodonta africana	33.03	3.00e-46	176.00
IUUC-Mcc-055107	Macaca mulatta	30.84	7.00e-36	142.00
IUUC-Mor-057029	Magnaporthe oryzae	37.46	2.00e-63	234.00
IUUC-Mla-059040	Melampsora laricipopulina	29.81	5.00e-32	129.00
IUUC-Mvi-060367	Microbotryum violaceum	35.54	8.00e-57	211.00
IUUC-Mmr-061294	Microcebus murinus	30.84	4.00e-35	139.00
IUUC-Mdo-062827	Monodelphis domestica	32.66	3.00e-46	176.00
IUUC-Mmu-063568	Mus musculus	32.43	1.00e-40	158.00
IUUC-Mpu-065826	Mustela putorius furo	32.13	2.00e-44	170.00
IUUC-Mlu-067751	Myotis lucifugus	31.45	2.00e-38	150.00
IUUC-Nfi-068597	Neosartorya fischeri	38.70	2.00e-66	243.00
IUUC-Ncr-068768	Neurospora crassa	38.59	2.00e-60	224.00
IUUC-Nle-069882	Nomascus leucogenys	41.18	9.00e-34	134.00
IUUC-Ont-072576	Oreochromis niloticus	30.65	7.00e-33	132.00
IUUC-Oan-073560	Ornithorhynchus anatinus	32.35	3.00e-34	136.00
IUUC-Ocu-074732	Oryctolagus cuniculus	30.06	3.00e-36	143.00
IUUC-Oba-075956	Oryza barthii	25.00	7.00e-29	119.00
IUUC-Obr-076004	Oryza brachyantha	25.58	2.00e-28	117.00
IUUC-Ogu-078335	Oryza glumaepatula	25.00	1.00e-28	118.00
IUUC-Oin-079177	Oryza indica	25.00	4.00e-29	119.00
IUUC-Ome-081880	Oryza meridionalis	25.00	4.00e-29	119.00
IUUC-Oni-082688	Oryza nivara	25.29	5.00e-30	122.00
IUUC-Opu-083231	Oryza punctata	25.42	2.00e-32	130.00
IUUC-Oru-084759	Oryza rufipogon	25.00	4.00e-29	119.00
IUUC-Osa-085601	Oryza sativa	25.00	2.00e-29	120.00
IUUC-Ola-086496	Oryzias latipes	31.88	3.00e-35	140.00
IUUC-Oga-089005	Otolemur garnettii	30.91	2.00e-43	167.00
IUUC-Oar-089611	Ovis aries	32.13	6.00e-44	169.00
IUUC-Ptr-091337	Pan troglodytes	33.63	1.00e-47	181.00
IUUC-Pan-092401	Papio anubis	31.82	3.00e-47	180.00
IUUC-Pma-094210	Petromyzon marinus	31.25	1.00e-40	158.00
IUUC-Pno-094975	Phaeosphaeria nodorum	33.24	3.00e-54	203.00
IUUC-Ppa-095925	Physcomitrella patens	27.59	7.00e-32	129.00
IUUC-Pfo-096890	Poecilia formosa	30.97	2.00e-36	144.00
IUUC-Pab-098173	Pongo abelii	33.63	2.00e-47	181.00
IUUC-Pva-102625	Pteropus vampyrus	31.23	2.00e-42	164.00
IUUC-Pgr-103426	Puccinia graminis	33.72	2.00e-48	184.00
IUUC-Pte-104082	Pyrenophora teres	37.90	8.00e-63	232.00
IUUC-Pyt-104818	Pyrenophora triticirepentis	37.21	4.00e-61	226.00
IUUC-Rno-106129	Rattus norvegicus	32.93	2.00e-47	180.00
IUUC-Sha-107120	Sarcophilus harrisii	29.47	1.00e-33	134.00
IUUC-Sja-107996	Schizosaccharomyces japonicus	27.35	9.00e-46	174.00
IUUC-Spo-108321	Schizosaccharomyces pombe	30.14	5.00e-44	169.00
IUUC-Ssl-108608	Sclerotinia sclerotiorum	37.64	6.00e-65	238.00
IUUC-Sit-110166	Setaria italica	26.35	2.00e-32	130.00
IUUC-Sar-113506	Sorex araneus	27.86	1.00e-31	128.00
IUUC-Sbi-114548	Sorghum bicolor	26.06	2.00e-29	120.00
IUUC-Sre-115022	Sporisorium reilianum	30.27	7.00e-31	125.00
IUUC-Ssc-115891	Sus scrofa	32.43	9.00e-45	171.00
IUUC-Tru-118469	Takifugu rubripes	30.59	1.00e-34	138.00
IUUC-Tsy-119304	Tarsius syrichta	27.62	9.00e-32	128.00
IUUC-Tni-119803	Tetraodon nigroviridis	29.36	1.00e-28	118.00
IUUC-Tre-122060	Trichoderma reesei	35.61	1.00e-59	221.00
IUUC-Tvi-122324	Trichoderma virens	36.42	3.00e-60	223.00
IUUC-Tae-123151	Triticum aestivum	25.60	5.00e-27	112.00
IUUC-Tur-126224	Triticum urartu	25.60	4.00e-27	113.00
IUUC-Tme-126939	Tuber melanosporum	43.06	1.00e-74	271.00
IUUC-Tbe-127982	Tupaia belangeri	30.30	2.00e-41	160.00
IUUC-Ttr-128758	Tursiops truncatus	31.83	8.00e-44	168.00
IUUC-Uma-129422	Ustilago maydis	27.67	3.00e-28	117.00
IUUC-Vda-129664	Verticillium dahliae	36.57	5.00e-62	229.00
IUUC-Vpa-130778	Vicugna pacos	37.95	3.00e-33	133.00
IUUC-Xtr-131919	Xenopus tropicalis	28.96	8.00e-39	152.00
IUUC-Xma-133482	Xiphophorus maculatus	31.27	1.00e-33	134.00
IUUC-Yli-134596	Yarrowia lipolytica	33.72	6.00e-55	205.00
IUUC-Zma-135688	Zea mays	26.06	7.00e-28	115.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence