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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063703
Ensembl Protein ID ENSMUSP00000061893.3
UniProt Accession Q8BYZ1; Q3TA46; Q6PE63; Q9D7S4; ABI3_MOUSE
Genbank Protein ID BAB25972.1; BAC29720.1; BAE42824.1; CAM15513.1; EDL15995.1; AAH58260.1
Protein Name ABI gene family member 3; New molecule including SH3
Genbank Nucleotide ID AK008928; AK037144; AK172098; AL593858; CH466556; BC058260
Gene Name Abi3; Nesh
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000018381.15 ENSMUST00000059026.9 ENSMUSP00000061893.3
ENSMUSG00000018381.15 ENSMUST00000137645.1 ENSMUSP00000119990.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 4.00e-11 43.8 311 364
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +ekv +ly+y+ q+d+eL++ +G v+ v      + gW++g    ++  G+fP n+ve
   Q: 311  LEKVVTLYPYTRQKDNELSFSEGTVICVT--RRYSDGWCEG--VSSEGTGFFPGNYVE 364
           589*************************7..999*******..688899********8 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility.
 Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility.
Protein Sequence
(Fasta)
MAELQQLQQL QEFDIPTGRE ALRGNHSALL RVANYCEDNY LQATDKRKAL EETMAFTTQA 60
LASVAYQVGN LAGHTLRMLD LQGAALRQVE AKMSTLGQMV NMHMEKVARR EIGTLATVVR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063703|UBD,SH3|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCAACTAGC TTCCTCTCCA GGACCAGGGA GCAATCACAG ATGCCCCGAC CTTGGCTTCC 60
TTTGCTTGGT GAGATTGAGA GACCGAGCCC CCAACAGGCC CCTGGTTTCC CCCTTCTCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063703|UBD,SH3|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR028457--ABI
IPR028455--ABI3
IPR012849--Abl-interactor_HHR_dom
IPR001452--SH3_domain
PROSITE

PS50002--SH3
Pfam

PF07815--Abi_HHR
PF14604--SH3_9
PRINTS

PR00452--SH3DOMAIN
SMART

SM00326--SH3
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005622--C:intracellular
GO:0030027--C:lamellipodium
GO:0016020--C:membrane
GO:0030334--P:regulation of cell migration
KEGG mmu:66610
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002253 Ailuropoda melanoleuca 86.53 8.00e-97 347.00
IUUC-Apl-003887 Anas platyrhynchos 60.27 2.00e-42 166.00
IUUC-Aca-005073 Anolis carolinensis 54.12 2.00e-49 189.00
IUUC-Bta-012731 Bos taurus 88.60 2.00e-99 355.00
IUUC-Cja-019927 Callithrix jacchus 87.37 2.00e-98 352.00
IUUC-Cfa-021246 Canis familiaris 86.30 4.00e-65 241.00
IUUC-Csa-023170 Chlorocebus sabaeus 90.16 4.00e-100 357.00
IUUC-Dno-030080 Dasypus novemcinctus 88.89 3.00e-79 288.00
IUUC-Dor-030777 Dipodomys ordii 89.64 4.00e-92 331.00
IUUC-Ete-032324 Echinops telfairi 86.99 2.00e-73 269.00
IUUC-Eca-034219 Equus caballus 73.54 1.00e-76 280.00
IUUC-Eeu-034475 Erinaceus europaeus 82.72 5.00e-72 264.00
IUUC-Fca-036479 Felis catus 87.05 2.00e-88 319.00
IUUC-Ggo-045520 Gorilla gorilla 89.64 2.00e-99 355.00
IUUC-Hsa-046385 Homo sapiens 90.16 4.00e-100 357.00
IUUC-Itr-048846 Ictidomys tridecemlineatus 89.59 5.00e-104 370.00
IUUC-Laf-053905 Loxodonta africana 89.06 4.00e-98 351.00
IUUC-Mcc-055351 Macaca mulatta 90.67 2.00e-100 359.00
IUUC-Meu-056867 Macropus eugenii 77.71 2.00e-79 289.00
IUUC-Mga-060205 Meleagris gallopavo 60.44 5.00e-53 201.00
IUUC-Mmr-060684 Microcebus murinus 91.71 1.00e-94 339.00
IUUC-Mdo-062899 Monodelphis domestica 74.43 1.00e-90 326.00
IUUC-Mpu-066022 Mustela putorius furo 86.86 2.00e-80 293.00
IUUC-Mlu-067886 Myotis lucifugus 89.64 1.00e-97 350.00
IUUC-Nle-069030 Nomascus leucogenys 90.16 6.00e-100 357.00
IUUC-Opr-070747 Ochotona princeps 88.08 1.00e-97 350.00
IUUC-Ocu-073874 Oryctolagus cuniculus 87.93 1.00e-87 316.00
IUUC-Oga-088294 Otolemur garnettii 87.33 1.00e-100 359.00
IUUC-Oar-089285 Ovis aries 88.36 5.00e-75 275.00
IUUC-Ptr-090972 Pan troglodytes 89.12 4.00e-99 354.00
IUUC-Pan-092463 Papio anubis 90.67 8.00e-94 337.00
IUUC-Pab-098655 Pongo abelii 89.64 1.00e-99 356.00
IUUC-Pca-100627 Procavia capensis 62.44 7.00e-60 224.00
IUUC-Pva-103217 Pteropus vampyrus 78.36 2.00e-66 245.00
IUUC-Rno-105415 Rattus norvegicus 96.55 7.00e-109 387.00
IUUC-Ssc-115938 Sus scrofa 85.34 1.00e-85 310.00
Created Date 25-Jun-2017

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