iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-43	144.4	302	334
UBD/Beta-Prp	3.30e-55	187.4	53	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           H  +v+++++ +   + l+s+sdDgtik+W ++
   Q: 302  HDQDVNSVQWnPVvaGQLISCSDDGTIKIWKVT 334
           999*******9444689*************986 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdls...tgkcvhtlkgheds 96
            l++ hk  i+ + +sp +++la++s d+t+ +w+ ++g +   ++l+ghe+ev++v++s++g +l+t+s+D+ + +w++     ++c  +l+ h+++
   Q: 53   ILSDGHKRTIREIRWSPCGQYLASASFDATTAIWSKSSGEFecNATLEGHENEVKSVSWSRSGGLLATCSRDKSVWIWEVAgddEFECAAVLNPHTQD 150
           57788999999999999999999999999999999999999888999999999999999999999999999999999988877799999999999999 PP
   S: 97   vlslsfspsgdklvsGshdrtirvwd...letgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWd 165
           v  + ++p++d l+s+s d+ti+++    +++++   +tl+ h+++v+++ ++ dg  lvs+s+D+t+++W+
   Q: 151  VKRVVWHPTKDILASASYDNTIKMFAeepIDNDWDCTATLTSHTSTVWGIDFDADGERLVSCSDDTTIKIWR 222
           999999999999999999999999753337788877779999999999999999999999999999999995 PP

Organism

Drosophila melanogaster

Functional Description
(View)

Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MGRLILEHTL QGHKGRIWGV AWHPKGNVFA SCGEDKAIRI WSLTGNTWST KTILSDGHKR 60
TIREIRWSPC GQYLASASFD ATTAIWSKSS GEFECNATLE GHENEVKSVS WSRSGGLLAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGACTTTC TTCTTCTTGC GACATGCGCT TATGTTATCA TTATTTGGAC AGACAGTGAT 60
TTGTCCACTA ATACAGCACT TGACCATCAA TGGGACGTTT AATTCTGGAA CACACGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly
GO:0022008--P:neurogenesis
GO:0019233--P:sensory perception of pain

KEGG

dme:Dmel_CG12797

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	49.08	9.00e-70	257.00
IUUC-Aml-001317	Ailuropoda melanoleuca	59.09	1.00e-107	382.00
IUUC-Atr-003029	Amborella trichopoda	50.89	1.00e-92	332.00
IUUC-Apl-004042	Anas platyrhynchos	54.48	4.00e-38	149.00
IUUC-Aly-006458	Arabidopsis lyrata	48.12	2.00e-88	318.00
IUUC-Ath-006671	Arabidopsis thaliana	48.12	1.00e-88	318.00
IUUC-Ago-007820	Ashbya gossypii	38.95	2.00e-55	208.00
IUUC-Acl-008042	Aspergillus clavatus	32.72	2.00e-48	185.00
IUUC-Afl-008639	Aspergillus flavus	35.31	1.00e-49	189.00
IUUC-Afu-008899	Aspergillus fumigatus	31.89	5.00e-46	177.00
IUUC-Ani-009453	Aspergillus nidulans	34.20	6.00e-49	187.00
IUUC-Ang-009758	Aspergillus niger	34.62	5.00e-48	184.00
IUUC-Aor-010212	Aspergillus oryzae	35.31	1.00e-49	189.00
IUUC-Ate-010314	Aspergillus terreus	33.58	5.00e-49	187.00
IUUC-Ame-010676	Astyanax mexicanus	58.84	2.00e-113	401.00
IUUC-Bgr-012095	Blumeria graminis	29.32	2.00e-33	135.00
IUUC-Bta-012884	Bos taurus	58.97	3.00e-108	384.00
IUUC-Bci-013622	Botrytis cinerea	29.16	4.00e-34	138.00
IUUC-Bdi-014614	Brachypodium distachyon	49.26	2.00e-87	314.00
IUUC-Bol-016439	Brassica oleracea	48.38	2.00e-86	311.00
IUUC-Bra-016830	Brassica rapa	47.34	1.00e-85	309.00
IUUC-Cel-018709	Caenorhabditis elegans	42.03	2.00e-67	248.00
IUUC-Cja-019822	Callithrix jacchus	58.48	3.00e-106	377.00
IUUC-Cfa-020823	Canis familiaris	58.79	6.00e-107	379.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	43.68	2.00e-70	258.00
IUUC-Csa-023754	Chlorocebus sabaeus	59.09	3.00e-108	384.00
IUUC-Cin-025395	Ciona intestinalis	57.06	1.00e-107	382.00
IUUC-Csv-025943	Ciona savignyi	57.23	1.00e-107	381.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	29.29	3.00e-34	139.00
IUUC-Cne-026939	Cryptococcus neoformans	29.62	8.00e-46	177.00
IUUC-Cme-027239	Cyanidioschyzon merolae	40.16	2.00e-45	176.00
IUUC-Dre-028172	Danio rerio	57.83	4.00e-113	400.00
IUUC-Dno-029472	Dasypus novemcinctus	61.81	2.00e-97	348.00
IUUC-Dor-031134	Dipodomys ordii	52.42	2.00e-86	311.00
IUUC-Dse-031535	Dothistroma septosporum	29.01	1.00e-40	159.00
IUUC-Eca-033700	Equus caballus	59.09	6.00e-108	383.00
IUUC-Eeu-035010	Erinaceus europaeus	58.79	2.00e-104	371.00
IUUC-Fca-036309	Felis catus	53.17	2.00e-97	348.00
IUUC-Fal-037243	Ficedula albicollis	56.62	5.00e-66	243.00
IUUC-Fox-038058	Fusarium oxysporum	32.72	2.00e-42	166.00
IUUC-Fso-038459	Fusarium solani	31.22	3.00e-37	148.00
IUUC-Gmo-039375	Gadus morhua	57.27	4.00e-102	363.00
IUUC-Ggr-040002	Gaeumannomyces graminis	33.04	6.00e-39	154.00
IUUC-Gga-040294	Gallus gallus	58.84	5.00e-89	320.00
IUUC-Gac-042499	Gasterosteus aculeatus	59.27	4.00e-104	370.00
IUUC-Gma-043543	Glycine max	47.98	3.00e-91	327.00
IUUC-Ggo-045181	Gorilla gorilla	59.09	3.00e-108	384.00
IUUC-Hsa-046528	Homo sapiens	59.09	3.00e-108	384.00
IUUC-Hvu-047341	Hordeum vulgare	57.89	2.00e-57	214.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	59.39	1.00e-108	385.00
IUUC-Kpa-049353	Komagataella pastoris	35.85	3.00e-57	214.00
IUUC-Lch-049763	Latimeria chalumnae	60.88	5.00e-109	386.00
IUUC-Lpe-051500	Leersia perrieri	44.89	2.00e-83	301.00
IUUC-Loc-052021	Lepisosteus oculatus	59.27	9.00e-105	372.00
IUUC-Lma-053331	Leptosphaeria maculans	33.00	4.00e-48	186.00
IUUC-Laf-054558	Loxodonta africana	58.48	9.00e-107	379.00
IUUC-Mcc-055374	Macaca mulatta	58.79	2.00e-107	381.00
IUUC-Meu-056042	Macropus eugenii	61.16	1.00e-71	261.00
IUUC-Mor-057187	Magnaporthe oryzae	30.97	7.00e-40	157.00
IUUC-Mtr-058072	Medicago truncatula	51.01	2.00e-94	338.00
IUUC-Mla-059108	Melampsora laricipopulina	32.49	1.00e-53	202.00
IUUC-Mga-059370	Meleagris gallopavo	46.91	2.00e-68	251.00
IUUC-Mvi-060495	Microbotryum violaceum	38.63	5.00e-59	221.00
IUUC-Mmr-060902	Microcebus murinus	59.39	2.00e-108	384.00
IUUC-Mdo-062510	Monodelphis domestica	58.48	1.00e-102	365.00
IUUC-Mmu-063575	Mus musculus	58.79	3.00e-107	380.00
IUUC-Mac-065322	Musa acuminata	51.64	1.00e-94	338.00
IUUC-Mpu-065925	Mustela putorius furo	58.79	4.00e-107	380.00
IUUC-Mlu-067755	Myotis lucifugus	58.79	4.00e-107	380.00
IUUC-Nfi-068327	Neosartorya fischeri	31.60	4.00e-45	174.00
IUUC-Ncr-068845	Neurospora crassa	28.60	2.00e-33	136.00
IUUC-Nle-069406	Nomascus leucogenys	57.58	8.00e-103	365.00
IUUC-Opr-070416	Ochotona princeps	61.64	3.00e-47	181.00
IUUC-Ont-071936	Oreochromis niloticus	59.46	1.00e-104	372.00
IUUC-Oan-073452	Ornithorhynchus anatinus	63.47	2.00e-51	193.00
IUUC-Ocu-074791	Oryctolagus cuniculus	58.56	1.00e-108	385.00
IUUC-Oba-075636	Oryza barthii	49.26	2.00e-89	321.00
IUUC-Obr-076742	Oryza brachyantha	50.35	2.00e-78	285.00
IUUC-Ogl-077766	Oryza glaberrima	49.26	2.00e-89	321.00
IUUC-Ogu-079039	Oryza glumaepatula	49.26	8.00e-90	322.00
IUUC-Oin-079315	Oryza indica	49.83	2.00e-78	285.00
IUUC-Olo-080669	Oryza longistaminata	43.08	1.00e-80	292.00
IUUC-Ome-081490	Oryza meridionalis	49.26	2.00e-89	321.00
IUUC-Oni-082572	Oryza nivara	49.26	2.00e-89	321.00
IUUC-Opu-083732	Oryza punctata	50.15	2.00e-91	328.00
IUUC-Oru-084763	Oryza rufipogon	49.26	2.00e-89	321.00
IUUC-Osa-085372	Oryza sativa	49.26	2.00e-89	321.00
IUUC-Ola-087379	Oryzias latipes	57.40	5.00e-101	359.00
IUUC-Olu-087801	Ostreococcus lucimarinus	38.51	9.00e-54	202.00
IUUC-Oga-089076	Otolemur garnettii	58.86	2.00e-108	384.00
IUUC-Oar-090022	Ovis aries	58.66	2.00e-108	384.00
IUUC-Ptr-090809	Pan troglodytes	59.09	3.00e-108	384.00
IUUC-Pan-091685	Papio anubis	59.09	7.00e-109	387.00
IUUC-Psi-093046	Pelodiscus sinensis	59.39	1.00e-106	378.00
IUUC-Pma-094181	Petromyzon marinus	55.86	3.00e-108	384.00
IUUC-Pno-094882	Phaeosphaeria nodorum	35.01	2.00e-48	185.00
IUUC-Ppa-095172	Physcomitrella patens	49.28	5.00e-87	313.00
IUUC-Pfo-096396	Poecilia formosa	58.86	1.00e-105	375.00
IUUC-Pab-098427	Pongo abelii	58.79	6.00e-106	376.00
IUUC-Pop-100016	Populus trichocarpa	50.89	1.00e-94	338.00
IUUC-Pca-101048	Procavia capensis	58.79	1.00e-106	379.00
IUUC-Ppe-102050	Prunus persica	48.39	1.00e-89	322.00
IUUC-Pva-103117	Pteropus vampyrus	59.09	1.00e-107	381.00
IUUC-Pgr-103307	Puccinia graminis	35.32	7.00e-57	213.00
IUUC-Ptt-103938	Puccinia triticina	40.00	1.00e-46	179.00
IUUC-Pte-104315	Pyrenophora teres	32.68	2.00e-48	186.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	32.43	5.00e-48	184.00
IUUC-Rno-105523	Rattus norvegicus	59.70	2.00e-108	384.00
IUUC-Sce-106297	Saccharomyces cerevisiae	36.44	1.00e-54	206.00
IUUC-Sha-106981	Sarcophilus harrisii	60.14	3.00e-92	330.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	39.88	9.00e-63	233.00
IUUC-Spo-108214	Schizosaccharomyces pombe	39.55	3.00e-59	222.00
IUUC-Smo-109034	Selaginella moellendorffii	45.85	4.00e-84	303.00
IUUC-Sit-110663	Setaria italica	49.25	4.00e-88	317.00
IUUC-Sly-110898	Solanum lycopersicum	48.96	5.00e-85	306.00
IUUC-Stu-112647	Solanum tuberosum	51.52	4.00e-72	263.00
IUUC-Sbi-114288	Sorghum bicolor	48.07	4.00e-86	310.00
IUUC-Sre-115065	Sporisorium reilianum	36.62	1.00e-67	249.00
IUUC-Ssc-115960	Sus scrofa	54.85	2.00e-108	384.00
IUUC-Tru-118382	Takifugu rubripes	58.75	2.00e-109	387.00
IUUC-Tsy-119585	Tarsius syrichta	54.24	1.00e-92	332.00
IUUC-Tni-120133	Tetraodon nigroviridis	57.78	2.00e-107	381.00
IUUC-Tca-121167	Theobroma cacao	50.30	4.00e-88	317.00
IUUC-Tre-122119	Trichoderma reesei	28.81	3.00e-37	148.00
IUUC-Tvi-122407	Trichoderma virens	28.50	2.00e-39	155.00
IUUC-Tae-124500	Triticum aestivum	48.37	4.00e-83	300.00
IUUC-Tur-126682	Triticum urartu	49.82	1.00e-70	258.00
IUUC-Tme-127095	Tuber melanosporum	35.92	4.00e-57	214.00
IUUC-Tbe-128004	Tupaia belangeri	59.09	5.00e-108	383.00
IUUC-Ttr-129284	Tursiops truncatus	56.67	3.00e-101	360.00
IUUC-Uma-129527	Ustilago maydis	36.53	7.00e-67	246.00
IUUC-Vda-129854	Verticillium dahliae	30.29	1.00e-35	143.00
IUUC-Vpa-130681	Vicugna pacos	67.24	2.00e-35	141.00
IUUC-Vvi-131004	Vitis vinifera	51.52	2.00e-87	315.00
IUUC-Xtr-131928	Xenopus tropicalis	55.76	1.00e-98	352.00
IUUC-Xma-134290	Xiphophorus maculatus	59.12	1.00e-101	361.00
IUUC-Yli-134364	Yarrowia lipolytica	41.16	4.00e-61	227.00
IUUC-Zma-135658	Zea mays	47.48	1.00e-83	302.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence