iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/MIU	47.06	6.10e-01	33.50	IUUC-Hsa-136748
DUB/MINDY	47.06	6.10e-01	33.50	IUUC-Hsa-136748

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Required for the establishment of the bipolar budding pattern. Involved in selecting bud sites at both the distal and proximal poles of daughter cells as well as near previously used division sites on mother cells. Has a role in the localization of BUD8, the distal bipolar budding landmark, and of BUD9, the proximal pole landmark.

Protein Sequence
(Fasta)

MKEELSKVSS MQNFEMIQRE RLPTLYEVLI QRTSQPVDLW TFYTFLSQFP YAINYLDFWV 60
DLMTHTRLCK NYIELVRKSL INFPQEQQQN GSTSTATFDL LNALIEEGHL DPEAPDKLLE 120

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Nucleotide Sequence
(Fasta)

ATGAAGGAAG AGCTCAGCAA AGTGAGCAGT ATGCAAAATT TCGAGATGAT CCAGCGTGAA 60
CGATTGCCAA CATTGTATGA AGTGTTAATA CAGAGGACAT CGCAGCCAGT TGATCTCTGG 120

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Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR016137--RGS

SMART

SM00315--RGS

Gene Ontology

GO:0005935--C:cellular bud neck
GO:0005934--C:cellular bud tip
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0000282--P:cellular bud site selection
GO:0008104--P:protein localization

KEGG

sce:YOR301W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-136425	Callithrix jacchus	35.19	7.50e-02	30.00
IUUC-Csa-136439	Chlorocebus sabaeus	44.12	3.60e-02	31.60
IUUC-Cgl-026636	Colletotrichum gloeosporioides	31.15	1.40e-01	28.10
IUUC-Gac-041327	Gasterosteus aculeatus	24.62	7.00e-03	32.70
IUUC-Ggo-136503	Gorilla gorilla	44.12	4.00e-02	31.60
IUUC-Hsa-136748	Homo sapiens	47.06	1.20e-02	33.10
IUUC-Mmr-136548	Microcebus murinus	38.89	5.00e-03	34.70
IUUC-Mlu-066960	Myotis lucifugus	37.04	2.50e+00	25.40
IUUC-Nle-136573	Nomascus leucogenys	33.33	3.20e-02	32.30
IUUC-Ptr-136624	Pan troglodytes	47.06	1.20e-02	33.10
IUUC-Pan-136628	Papio anubis	44.12	4.00e-02	31.60
IUUC-Pab-136646	Pongo abelii	44.12	3.00e-02	32.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence