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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063269
Ensembl Protein ID ENSMUSP00000059880.7
UniProt Accession Q9CWU9; Q9CZ80; NUP37_MOUSE
Genbank Protein ID BAB26888.1; BAB28538.1; BAC30597.1; BAE38243.1; EDL21469.1; EDL21470.1; EDL21471.1; AAH11102.1; AAH32180.1
Protein Name Nucleoporin Nup37; Nup107-160 subcomplex subunit Nup37
Genbank Nucleotide ID AK010370; AK012890; AK040463; AK165537; CH466539; CH466539; CH466539; BC011102; BC032180
Gene Name Nup37
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000035351.15 ENSMUST00000052355.13 ENSMUSP00000059880.7
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarmiRNAMap
RAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
CPLMPhosphositePlusmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.00e-06 29.9 122 154
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDl 30
           gH+d +++l f   +   l+s sdD+t+++W+l
   Q: 122  GHSDFINDLVFhpKEgQELASVSDDHTCRIWNL 154
           8**********9644688**************7 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation (By similarity).
 Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation (By similarity).
Protein Sequence
(Fasta)
MKQDATRNAA YTVDCEDYVH VVEFNPFESG DSGNLIAYGG SNYVVVGMCT FQEEETDIEG 60
IQYKTLRTFH HGVRVDGIAW SPETKLDSLP PVIKFCTSAA DLKIRLFTSD LQDKNEYKVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063269|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGACCCGGA AGCAGAGCGG GCGCACGCCC TGGCCACCTA TGGTCGGGAG AGCCTTGCCC 60
AGGTCGCCTC CCCTGCTTTA GGTGCGTATC GAGTGCGGTG ACCGGGGATC GCCAGCTTGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063269|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0137--Centromere
KW-0158--Chromosome
KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-0995--Kinetochore
KW-0498--Mitosis
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0000777--C:condensed chromosome kinetochore
GO:0031080--C:nuclear pore outer ring
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0051301--P:cell division
GO:0007059--P:chromosome segregation
GO:0007067--P:mitotic nuclear division
GO:0051028--P:mRNA transport
GO:0015031--P:protein transport
KEGG mmu:69736
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002109 Ailuropoda melanoleuca 92.02 3.00e-178 617.00
IUUC-Aca-004272 Anolis carolinensis 74.85 7.00e-156 543.00
IUUC-Bta-012525 Bos taurus 90.80 0.00e+00 637.00
IUUC-Cfa-020623 Canis familiaris 91.10 0.00e+00 638.00
IUUC-Cpo-021545 Cavia porcellus 87.73 1.00e-178 618.00
IUUC-Csa-023698 Chlorocebus sabaeus 91.10 0.00e+00 642.00
IUUC-Cho-024401 Choloepus hoffmanni 87.40 1.00e-136 478.00
IUUC-Cin-025648 Ciona intestinalis 35.94 3.00e-42 165.00
IUUC-Csv-025913 Ciona savignyi 31.54 4.00e-37 148.00
IUUC-Dre-027990 Danio rerio 66.56 7.00e-139 486.00
IUUC-Dor-031077 Dipodomys ordii 88.99 4.00e-180 623.00
IUUC-Dme-031831 Drosophila melanogaster 31.77 8.00e-41 160.00
IUUC-Ete-032819 Echinops telfairi 87.42 3.00e-179 620.00
IUUC-Eca-033212 Equus caballus 92.64 0.00e+00 644.00
IUUC-Fca-036071 Felis catus 90.03 0.00e+00 634.00
IUUC-Fal-036718 Ficedula albicollis 77.61 2.00e-164 571.00
IUUC-Gmo-039710 Gadus morhua 65.64 9.00e-139 486.00
IUUC-Gga-041026 Gallus gallus 76.99 8.00e-164 569.00
IUUC-Gac-041726 Gasterosteus aculeatus 66.87 1.00e-141 496.00
IUUC-Ggo-045372 Gorilla gorilla 91.41 0.00e+00 644.00
IUUC-Hsa-046002 Homo sapiens 91.10 0.00e+00 641.00
IUUC-Itr-048542 Ictidomys tridecemlineatus 90.80 0.00e+00 637.00
IUUC-Lch-049456 Latimeria chalumnae 73.01 2.00e-143 501.00
IUUC-Loc-052159 Lepisosteus oculatus 55.65 3.00e-115 407.00
IUUC-Laf-053514 Loxodonta africana 88.04 1.00e-180 625.00
IUUC-Mcc-055148 Macaca mulatta 91.10 0.00e+00 641.00
IUUC-Meu-056644 Macropus eugenii 66.56 2.00e-129 455.00
IUUC-Mga-060061 Meleagris gallopavo 76.69 8.00e-163 566.00
IUUC-Mmr-061448 Microcebus murinus 91.10 0.00e+00 643.00
IUUC-Mdo-063006 Monodelphis domestica 83.44 5.00e-173 600.00
IUUC-Mpu-066663 Mustela putorius furo 90.80 0.00e+00 635.00
IUUC-Nle-069989 Nomascus leucogenys 91.10 0.00e+00 641.00
IUUC-Ont-072544 Oreochromis niloticus 66.56 3.00e-138 484.00
IUUC-Oan-073360 Ornithorhynchus anatinus 80.31 1.00e-168 585.00
IUUC-Ola-087370 Oryzias latipes 62.88 8.00e-131 459.00
IUUC-Oar-089696 Ovis aries 90.80 0.00e+00 638.00
IUUC-Ptr-091333 Pan troglodytes 91.10 0.00e+00 641.00
IUUC-Pan-091814 Papio anubis 91.10 0.00e+00 641.00
IUUC-Psi-093497 Pelodiscus sinensis 80.37 8.00e-169 586.00
IUUC-Pfo-096789 Poecilia formosa 67.58 2.00e-140 492.00
IUUC-Pab-098451 Pongo abelii 90.80 0.00e+00 640.00
IUUC-Pca-101057 Procavia capensis 72.63 7.00e-115 406.00
IUUC-Pva-102866 Pteropus vampyrus 92.02 0.00e+00 644.00
IUUC-Pgr-103570 Puccinia graminis 25.09 4.00e-10 58.90
IUUC-Rno-106000 Rattus norvegicus 96.01 0.00e+00 664.00
IUUC-Sha-106639 Sarcophilus harrisii 83.74 7.00e-174 602.00
IUUC-Sja-108011 Schizosaccharomyces japonicus 25.00 3.00e-08 53.10
IUUC-Spo-108334 Schizosaccharomyces pombe 28.00 2.00e-09 56.60
IUUC-Ssc-115982 Sus scrofa 86.50 1.00e-143 502.00
IUUC-Tgu-116575 Taeniopygia guttata 77.30 1.00e-163 568.00
IUUC-Tru-117729 Takifugu rubripes 66.56 4.00e-139 487.00
IUUC-Tsy-118870 Tarsius syrichta 76.07 6.00e-148 516.00
IUUC-Tni-120524 Tetraodon nigroviridis 67.48 5.00e-139 487.00
IUUC-Ttr-128693 Tursiops truncatus 85.89 4.00e-163 566.00
IUUC-Vpa-130328 Vicugna pacos 88.58 2.00e-166 577.00
IUUC-Xtr-132017 Xenopus tropicalis 69.94 3.00e-145 507.00
Created Date 25-Jun-2017

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