iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0003162	FBtr0071579	FBpp0071506
FBgn0003162	FBtr0071580	FBpp0071507
FBgn0003162	FBtr0071578	FBpp0071505

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	76.50	2.00e-72	270.00	IUUC-Hsa-046907

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Functional Description
(View)

Isoform B is required for eye pigment production, Isoform C may be required for normal embryonic development and segment pattern formation.

Protein Sequence
(Fasta)

MKPQTSEQNG SGQNGEGAAD AVAVATIPTG EASAASATSG TDLTVSKNSQ QLKLEMLNLE 60
LASNGSGHEK CTFHHDLELD HKPPTREALL PDMARSYRLL LGGLGENPDR QGLIKTPERA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTTAGTCG GCAGATAAAT TCGGAGCGAG CGCGCCAAAT ACAAAAGTCC GCCACGCGTT 60
CAGAGCCCCA ATCTCAAGTC CCATAGTTCA AACAGTTCCG AGCCCGTGTC CTCGCAGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0021--Allosteric enzyme
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0783--Tetrahydrobiopterin biosynthesis
KW-0862--Zinc

Interpro

IPR001474--GTP_CycHdrlase_I
IPR018234--GTP_CycHdrlase_I_CS
IPR020602--GTP_CycHdrlase_I_dom

PROSITE

PS00859--GTP_CYCLOHYDROL_1_1
PS00860--GTP_CYCLOHYDROL_1_2

Pfam

PF01227--GTP_cyclohydroI

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005525--F:GTP binding
GO:0003934--F:GTP cyclohydrolase I activity
GO:0060308--F:GTP cyclohydrolase I regulator activity
GO:0046872--F:metal ion binding
GO:0035998--P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process
GO:0048072--P:compound eye pigmentation
GO:0048067--P:cuticle pigmentation
GO:0009880--P:embryonic pattern specification
GO:0008363--P:larval chitin-based cuticle development
GO:0035185--P:preblastoderm mitotic cell cycle
GO:0006728--P:pteridine biosynthetic process
GO:2000274--P:regulation of epithelial cell migration, open tracheal system
GO:0043095--P:regulation of GTP cyclohydrolase I activity
GO:0006729--P:tetrahydrobiopterin biosynthetic process
GO:0046654--P:tetrahydrofolate biosynthetic process

KEGG

dme:Dmel_CG9441

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002530	Amborella trichopoda	34.65	5.00e-23	101.00
IUUC-Apl-004135	Anas platyrhynchos	71.51	3.00e-73	266.00
IUUC-Aca-005252	Anolis carolinensis	72.13	9.00e-76	275.00
IUUC-Aly-006454	Arabidopsis lyrata	38.22	2.00e-25	109.00
IUUC-Ath-006744	Arabidopsis thaliana	37.77	5.00e-25	108.00
IUUC-Ago-007744	Ashbya gossypii	68.00	2.00e-63	234.00
IUUC-Acl-008058	Aspergillus clavatus	60.00	1.00e-66	245.00
IUUC-Afl-008668	Aspergillus flavus	59.49	2.00e-66	244.00
IUUC-Afu-008935	Aspergillus fumigatus	60.00	2.00e-66	244.00
IUUC-Ani-009207	Aspergillus nidulans	60.51	2.00e-67	248.00
IUUC-Ang-009686	Aspergillus niger	62.43	2.00e-65	241.00
IUUC-Aor-010202	Aspergillus oryzae	59.49	2.00e-66	244.00
IUUC-Ate-010518	Aspergillus terreus	59.49	7.00e-66	243.00
IUUC-Ame-010958	Astyanax mexicanus	69.74	6.00e-78	282.00
IUUC-Bgr-012060	Blumeria graminis	53.72	3.00e-57	214.00
IUUC-Bta-012416	Bos taurus	75.41	1.00e-78	285.00
IUUC-Bci-013811	Botrytis cinerea	54.17	7.00e-59	219.00
IUUC-Bdi-014794	Brachypodium distachyon	36.31	2.00e-20	92.80
IUUC-Bol-015182	Brassica oleracea	39.67	7.00e-28	117.00
IUUC-Bra-016764	Brassica rapa	39.57	6.00e-26	111.00
IUUC-Cel-018345	Caenorhabditis elegans	73.40	3.00e-78	283.00
IUUC-Cja-019848	Callithrix jacchus	81.88	7.00e-62	228.00
IUUC-Cfa-020630	Canis familiaris	75.96	5.00e-79	286.00
IUUC-Cpo-021420	Cavia porcellus	79.17	1.00e-75	274.00
IUUC-Cre-022618	Chlamydomonas reinhardtii	40.31	2.00e-31	128.00
IUUC-Csa-023403	Chlorocebus sabaeus	72.13	1.00e-65	241.00
IUUC-Cho-024907	Choloepus hoffmanni	75.41	6.00e-79	286.00
IUUC-Cin-025120	Ciona intestinalis	65.91	2.00e-60	224.00
IUUC-Csv-026259	Ciona savignyi	66.30	1.00e-70	258.00
IUUC-Cgl-026508	Colletotrichum gloeosporioides	54.87	2.00e-60	225.00
IUUC-Cne-026810	Cryptococcus neoformans	62.76	2.00e-67	249.00
IUUC-Cme-027139	Cyanidioschyzon merolae	40.08	2.00e-46	178.00
IUUC-Dre-028815	Danio rerio	74.73	4.00e-79	286.00
IUUC-Dno-029017	Dasypus novemcinctus	77.97	5.00e-78	283.00
IUUC-Dor-030417	Dipodomys ordii	82.22	8.00e-61	224.00
IUUC-Dse-031187	Dothistroma septosporum	61.41	2.00e-64	238.00
IUUC-Ete-032727	Echinops telfairi	48.48	4.00e-30	123.00
IUUC-Eca-033487	Equus caballus	82.61	2.00e-61	226.00
IUUC-Eeu-034696	Erinaceus europaeus	75.41	2.00e-75	274.00
IUUC-Fca-035975	Felis catus	83.33	6.00e-31	124.00
IUUC-Fal-037439	Ficedula albicollis	79.19	2.00e-66	243.00
IUUC-Fox-037781	Fusarium oxysporum	57.87	6.00e-59	220.00
IUUC-Fso-038377	Fusarium solani	58.01	5.00e-58	217.00
IUUC-Gmo-038945	Gadus morhua	68.23	1.00e-72	265.00
IUUC-Ggr-039834	Gaeumannomyces graminis	58.33	4.00e-63	233.00
IUUC-Gga-040495	Gallus gallus	74.19	4.00e-79	286.00
IUUC-Gac-042306	Gasterosteus aculeatus	73.77	5.00e-78	283.00
IUUC-Gma-043539	Glycine max	36.26	5.00e-26	111.00
IUUC-Ggo-045597	Gorilla gorilla	65.48	2.00e-58	218.00
IUUC-Hsa-046907	Homo sapiens	79.76	9.00e-76	275.00
IUUC-Hvu-047298	Hordeum vulgare	40.52	9.00e-25	107.00
IUUC-Itr-048997	Ictidomys tridecemlineatus	75.41	2.00e-78	284.00
IUUC-Kpa-049319	Komagataella pastoris	59.59	8.00e-64	235.00
IUUC-Lch-049771	Latimeria chalumnae	74.86	3.00e-79	286.00
IUUC-Lpe-050904	Leersia perrieri	40.54	2.00e-24	106.00
IUUC-Loc-052063	Lepisosteus oculatus	76.34	3.00e-81	293.00
IUUC-Lma-053280	Leptosphaeria maculans	48.44	8.00e-44	170.00
IUUC-Laf-054214	Loxodonta africana	75.96	5.00e-79	286.00
IUUC-Mcc-054778	Macaca mulatta	79.76	9.00e-76	275.00
IUUC-Meu-056598	Macropus eugenii	82.61	4.00e-25	107.00
IUUC-Mor-056989	Magnaporthe oryzae	55.73	2.00e-60	224.00
IUUC-Mpo-057591	Magnaporthe poae	57.81	6.00e-63	233.00
IUUC-Mtr-057924	Medicago truncatula	36.87	2.00e-28	119.00
IUUC-Mla-058931	Melampsora laricipopulina	67.60	5.00e-68	250.00
IUUC-Mga-060001	Meleagris gallopavo	80.43	8.00e-62	228.00
IUUC-Mvi-060513	Microbotryum violaceum	62.98	1.00e-63	235.00
IUUC-Mmr-061725	Microcebus murinus	75.41	1.00e-78	285.00
IUUC-Mdo-062715	Monodelphis domestica	75.41	2.00e-78	285.00
IUUC-Mmu-063203	Mus musculus	79.17	6.00e-76	276.00
IUUC-Mac-065392	Musa acuminata	42.29	1.00e-32	132.00
IUUC-Mpu-066174	Mustela putorius furo	75.96	6.00e-79	286.00
IUUC-Mlu-067883	Myotis lucifugus	81.88	7.00e-62	228.00
IUUC-Nfi-068317	Neosartorya fischeri	60.00	2.00e-66	244.00
IUUC-Ncr-068822	Neurospora crassa	57.29	1.00e-62	232.00
IUUC-Nle-069231	Nomascus leucogenys	79.76	1.00e-75	275.00
IUUC-Opr-070417	Ochotona princeps	82.96	8.00e-61	224.00
IUUC-Ont-072168	Oreochromis niloticus	73.66	9.00e-79	285.00
IUUC-Oan-072690	Ornithorhynchus anatinus	83.33	6.00e-31	124.00
IUUC-Ocu-074537	Oryctolagus cuniculus	75.96	1.00e-78	285.00
IUUC-Oba-075333	Oryza barthii	40.52	1.00e-25	110.00
IUUC-Obr-076255	Oryza brachyantha	37.22	1.00e-23	102.00
IUUC-Ogl-077792	Oryza glaberrima	41.22	7.00e-26	109.00
IUUC-Ogu-078354	Oryza glumaepatula	41.22	2.00e-25	109.00
IUUC-Oin-079934	Oryza indica	40.54	7.00e-25	107.00
IUUC-Olo-080643	Oryza longistaminata	37.16	4.00e-23	101.00
IUUC-Ome-081632	Oryza meridionalis	41.10	6.00e-25	107.00
IUUC-Oni-083004	Oryza nivara	40.54	6.00e-25	107.00
IUUC-Opu-083899	Oryza punctata	41.22	2.00e-25	109.00
IUUC-Oru-084386	Oryza rufipogon	41.22	2.00e-25	109.00
IUUC-Osa-085665	Oryza sativa	37.16	2.00e-23	102.00
IUUC-Ola-086577	Oryzias latipes	65.31	2.00e-73	267.00
IUUC-Olu-087867	Ostreococcus lucimarinus	41.88	2.00e-34	137.00
IUUC-Oga-088652	Otolemur garnettii	79.17	2.00e-74	270.00
IUUC-Oar-089965	Ovis aries	75.96	1.00e-79	288.00
IUUC-Ptr-090833	Pan troglodytes	79.76	9.00e-76	275.00
IUUC-Psi-093542	Pelodiscus sinensis	67.76	5.00e-68	249.00
IUUC-Pma-094423	Petromyzon marinus	76.22	4.00e-59	219.00
IUUC-Pno-095091	Phaeosphaeria nodorum	63.54	3.00e-65	241.00
IUUC-Ppa-096013	Physcomitrella patens	41.78	9.00e-29	120.00
IUUC-Pfo-097146	Poecilia formosa	74.19	3.00e-79	286.00
IUUC-Pab-098744	Pongo abelii	79.76	9.00e-76	275.00
IUUC-Pop-099917	Populus trichocarpa	41.22	3.00e-24	105.00
IUUC-Pca-100111	Procavia capensis	75.96	6.00e-79	286.00
IUUC-Ppe-101984	Prunus persica	40.11	7.00e-24	104.00
IUUC-Pva-103078	Pteropus vampyrus	74.86	3.00e-76	277.00
IUUC-Pgr-103438	Puccinia graminis	59.36	2.00e-62	231.00
IUUC-Ptt-103875	Puccinia triticina	60.89	3.00e-61	227.00
IUUC-Pte-104180	Pyrenophora teres	63.74	6.00e-65	240.00
IUUC-Pyt-104552	Pyrenophora triticirepentis	63.74	3.00e-65	241.00
IUUC-Rno-105506	Rattus norvegicus	75.41	5.00e-79	286.00
IUUC-Sce-106375	Saccharomyces cerevisiae	62.01	5.00e-60	223.00
IUUC-Sha-107585	Sarcophilus harrisii	81.16	4.00e-61	225.00
IUUC-Sja-107871	Schizosaccharomyces japonicus	64.33	4.00e-63	233.00
IUUC-Spo-108282	Schizosaccharomyces pombe	65.50	3.00e-63	233.00
IUUC-Smo-109561	Selaginella moellendorffii	41.80	1.00e-26	113.00
IUUC-Sit-110577	Setaria italica	33.76	8.00e-23	100.00
IUUC-Sly-111719	Solanum lycopersicum	39.71	2.00e-25	109.00
IUUC-Stu-112752	Solanum tuberosum	40.67	1.00e-26	113.00
IUUC-Sar-113701	Sorex araneus	75.82	2.00e-78	284.00
IUUC-Sbi-114308	Sorghum bicolor	38.34	5.00e-27	114.00
IUUC-Sre-115125	Sporisorium reilianum	53.60	2.00e-65	242.00
IUUC-Tgu-117039	Taeniopygia guttata	81.16	7.00e-62	228.00
IUUC-Tru-117939	Takifugu rubripes	73.12	8.00e-78	282.00
IUUC-Tsy-118852	Tarsius syrichta	73.33	1.00e-50	190.00
IUUC-Tni-120356	Tetraodon nigroviridis	72.04	2.00e-77	280.00
IUUC-Tca-121422	Theobroma cacao	34.10	9.00e-27	114.00
IUUC-Tre-122035	Trichoderma reesei	58.03	5.00e-62	229.00
IUUC-Tvi-122649	Trichoderma virens	59.14	2.00e-61	228.00
IUUC-Tae-124146	Triticum aestivum	39.87	5.00e-26	110.00
IUUC-Tme-127015	Tuber melanosporum	59.38	2.00e-63	234.00
IUUC-Tbe-128024	Tupaia belangeri	72.59	4.00e-50	188.00
IUUC-Ttr-128474	Tursiops truncatus	56.98	6.00e-79	286.00
IUUC-Uma-129655	Ustilago maydis	61.03	1.00e-66	246.00
IUUC-Vda-129970	Verticillium dahliae	55.38	3.00e-60	224.00
IUUC-Vpa-130564	Vicugna pacos	82.22	1.00e-60	223.00
IUUC-Vvi-131597	Vitis vinifera	37.59	4.00e-24	104.00
IUUC-Xtr-132201	Xenopus tropicalis	75.41	6.00e-79	285.00
IUUC-Xma-133679	Xiphophorus maculatus	74.19	3.00e-79	286.00
IUUC-Yli-134489	Yarrowia lipolytica	62.43	2.00e-65	241.00
IUUC-Zma-135058	Zea mays	36.68	4.00e-26	111.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence