• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064090
Ensembl Protein ID ENSMUSP00000049258.7
UniProt Accession A2AH22; A2AH21; A2AH24; Q3TF60; Q3U239; Q3UF70; Q6ZPJ1; Q8BJJ8; Q8BYW8; AMRA1_MOUSE
Genbank Protein ID BAC29823.1; BAC38965.1; BAE28691.1; BAE33303.1; BAE41038.1; CAM14517.1; CAM14517.1; CAM14518.1; CAM14518.1; CAM14519.1; CAM14519.1; CAM14520.1; CAM14520.1; CAM19280.1; CAM19280.1; CAM19281.1; CAM19281.1; CAM19282.1; CAM19282.1; CAM19283.1; CAM19283.1; BAC98243.1
Protein Name Activating molecule in BECN1-regulated autophagy protein 1
Genbank Nucleotide ID AK037516; AK083596; AK148887; AK155513; AK169280; AL714023; AL731772; AL714023; AL731772; AL714023; AL731772; AL714023; AL731772; AL731772; AL714023; AL731772; AL714023; AL731772; AL714023; AL731772; AL714023; AK129433
Gene Name Ambra1; Kiaa1736
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000040506.16 ENSMUST00000099712.9 ENSMUSP00000097299.3
ENSMUSG00000040506.16 ENSMUST00000045705.13 ENSMUSP00000049258.7
ENSMUSG00000040506.16 ENSMUST00000111316.8 ENSMUSP00000106948.2
ENSMUSG00000040506.16 ENSMUST00000045699.7 ENSMUSP00000048898.7
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemiRTarBasemicroRNA
TRANSFACmiRNAMapRAID2
Protein-protein Interaction
IIDHINT
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusUniProt
mUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.60e-07 32.5 93 126
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 93   GHRRTPWCVTFhPTisGLIASGCLDGEVRIWDLH 126
           6777779*****76779***************97 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
 Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
Protein Sequence
(Fasta)
MKVVPEKNAV RILWGRERGT RAMGAQRLLQ ELVEDKTRWM KWEGKRVELP DSPRSTFLLA 60
FSPDRTLLAS THVNHNIYIT EVKTGKCVHS LIGHRRTPWC VTFHPTISGL IASGCLDGEV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064090|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTCCTTTGAT GTCTGGGCGT TCGTGTGTTC GATGATCTTT TGCGGCGTCT TCTTGGTTGA 60
TGTCTCCGGA GCGGCGGCGG CTGTGCCAGG TCCTGGACTG AGTTATCCCG GAGGCCCCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064090|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0072--Autophagy
KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0488--Methylation
KW-0524--Neurogenesis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0005776--C:autophagosome
GO:0005930--C:axoneme
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0031625--F:ubiquitin protein ligase binding
GO:0006914--P:autophagy
GO:0030154--P:cell differentiation
GO:0009267--P:cellular response to starvation
GO:0010667--P:negative regulation of cardiac muscle cell apoptotic process
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:1903599--P:positive regulation of mitophagy
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly
KEGG mmu:228361
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001917 Ailuropoda melanoleuca 96.51 0.00e+00 1778.00
IUUC-Atr-002557 Amborella trichopoda 37.74 4.00e-30 127.00
IUUC-Apl-004186 Anas platyrhynchos 81.07 0.00e+00 1907.00
IUUC-Aca-004419 Anolis carolinensis 76.64 0.00e+00 1782.00
IUUC-Aly-006308 Arabidopsis lyrata 37.85 8.00e-29 122.00
IUUC-Ath-007656 Arabidopsis thaliana 37.09 2.00e-28 120.00
IUUC-Ame-011354 Astyanax mexicanus 60.38 0.00e+00 1219.00
IUUC-Bta-012455 Bos taurus 92.67 0.00e+00 2126.00
IUUC-Bdi-014580 Brachypodium distachyon 42.33 4.00e-30 127.00
IUUC-Bol-016094 Brassica oleracea 40.22 9.00e-29 122.00
IUUC-Bra-017308 Brassica rapa 40.76 9.00e-30 125.00
IUUC-Cja-019073 Callithrix jacchus 94.69 9.00e-160 557.00
IUUC-Cfa-020994 Canis familiaris 91.88 0.00e+00 1471.00
IUUC-Cpo-022101 Cavia porcellus 94.46 0.00e+00 2187.00
IUUC-Csa-023273 Chlorocebus sabaeus 94.26 0.00e+00 1564.00
IUUC-Cin-025567 Ciona intestinalis 52.20 3.00e-56 213.00
IUUC-Csv-026005 Ciona savignyi 51.26 5.00e-56 210.00
IUUC-Dre-028282 Danio rerio 60.14 0.00e+00 1201.00
IUUC-Dno-029948 Dasypus novemcinctus 94.31 0.00e+00 2173.00
IUUC-Dor-030568 Dipodomys ordii 96.64 0.00e+00 1253.00
IUUC-Ete-032864 Echinops telfairi 93.20 0.00e+00 1158.00
IUUC-Eca-034392 Equus caballus 94.36 0.00e+00 1585.00
IUUC-Eeu-034440 Erinaceus europaeus 86.56 0.00e+00 1214.00
IUUC-Fca-035359 Felis catus 92.88 0.00e+00 2129.00
IUUC-Fal-037483 Ficedula albicollis 81.29 0.00e+00 1925.00
IUUC-Gmo-039343 Gadus morhua 75.54 0.00e+00 755.00
IUUC-Gga-040787 Gallus gallus 81.97 0.00e+00 1224.00
IUUC-Gac-041321 Gasterosteus aculeatus 60.92 0.00e+00 1330.00
IUUC-Gma-044022 Glycine max 36.63 3.00e-29 124.00
IUUC-Ggo-044775 Gorilla gorilla 93.97 0.00e+00 1035.00
IUUC-Hsa-045708 Homo sapiens 95.69 0.00e+00 2227.00
IUUC-Hvu-047536 Hordeum vulgare 41.57 1.00e-29 124.00
IUUC-Itr-048376 Ictidomys tridecemlineatus 97.40 0.00e+00 1254.00
IUUC-Lch-050255 Latimeria chalumnae 69.46 0.00e+00 1390.00
IUUC-Lpe-050684 Leersia perrieri 41.76 1.00e-30 128.00
IUUC-Loc-052881 Lepisosteus oculatus 68.91 0.00e+00 1386.00
IUUC-Laf-053342 Loxodonta africana 73.28 0.00e+00 1001.00
IUUC-Mcc-055848 Macaca mulatta 93.38 0.00e+00 2195.00
IUUC-Meu-056320 Macropus eugenii 84.64 0.00e+00 1080.00
IUUC-Mtr-058685 Medicago truncatula 39.68 3.00e-29 124.00
IUUC-Mga-059401 Meleagris gallopavo 84.97 0.00e+00 1660.00
IUUC-Mmr-061037 Microcebus murinus 94.78 0.00e+00 2167.00
IUUC-Mdo-062484 Monodelphis domestica 74.30 0.00e+00 1640.00
IUUC-Mac-065675 Musa acuminata 36.20 2.00e-29 124.00
IUUC-Mpu-066165 Mustela putorius furo 93.74 0.00e+00 1494.00
IUUC-Mlu-068038 Myotis lucifugus 94.16 0.00e+00 2251.00
IUUC-Nle-069361 Nomascus leucogenys 97.05 0.00e+00 1940.00
IUUC-Opr-070360 Ochotona princeps 90.94 0.00e+00 845.00
IUUC-Ont-071277 Oreochromis niloticus 76.74 0.00e+00 772.00
IUUC-Oan-073623 Ornithorhynchus anatinus 82.62 0.00e+00 1021.00
IUUC-Ocu-074600 Oryctolagus cuniculus 95.99 0.00e+00 1367.00
IUUC-Oba-075024 Oryza barthii 34.30 5.00e-32 133.00
IUUC-Obr-076172 Oryza brachyantha 34.30 3.00e-32 133.00
IUUC-Ogl-077411 Oryza glaberrima 34.30 5.00e-32 132.00
IUUC-Ogu-078025 Oryza glumaepatula 38.19 7.00e-32 133.00
IUUC-Oni-082463 Oryza nivara 34.30 5.00e-32 133.00
IUUC-Opu-084041 Oryza punctata 34.30 1.00e-31 132.00
IUUC-Oru-085075 Oryza rufipogon 38.19 2.00e-31 131.00
IUUC-Osa-085781 Oryza sativa 34.30 5.00e-32 132.00
IUUC-Ola-086729 Oryzias latipes 63.72 0.00e+00 1348.00
IUUC-Olu-087735 Ostreococcus lucimarinus 40.32 8.00e-24 105.00
IUUC-Oga-089113 Otolemur garnettii 93.46 0.00e+00 2110.00
IUUC-Oar-090171 Ovis aries 94.71 0.00e+00 2016.00
IUUC-Ptr-090970 Pan troglodytes 95.69 0.00e+00 2227.00
IUUC-Pan-092778 Papio anubis 94.15 0.00e+00 1574.00
IUUC-Psi-093571 Pelodiscus sinensis 81.09 0.00e+00 1910.00
IUUC-Pma-094563 Petromyzon marinus 74.17 5.00e-106 377.00
IUUC-Ppa-095832 Physcomitrella patens 36.70 2.00e-30 128.00
IUUC-Pfo-097365 Poecilia formosa 60.69 0.00e+00 1251.00
IUUC-Pab-098647 Pongo abelii 96.39 0.00e+00 1230.00
IUUC-Pop-099742 Populus trichocarpa 40.32 1.00e-29 125.00
IUUC-Pca-101035 Procavia capensis 91.68 0.00e+00 1169.00
IUUC-Ppe-101411 Prunus persica 37.56 2.00e-29 124.00
IUUC-Pva-103187 Pteropus vampyrus 97.63 0.00e+00 929.00
IUUC-Rno-105701 Rattus norvegicus 99.00 0.00e+00 2286.00
IUUC-Sha-107612 Sarcophilus harrisii 84.27 0.00e+00 1943.00
IUUC-Smo-108871 Selaginella moellendorffii 39.08 8.00e-27 115.00
IUUC-Sit-110786 Setaria italica 41.62 2.00e-32 134.00
IUUC-Sly-110859 Solanum lycopersicum 38.10 5.00e-32 132.00
IUUC-Stu-112031 Solanum tuberosum 38.57 4.00e-32 133.00
IUUC-Sar-113242 Sorex araneus 94.53 0.00e+00 1069.00
IUUC-Ssc-116094 Sus scrofa 94.70 0.00e+00 2209.00
IUUC-Tru-118308 Takifugu rubripes 61.72 0.00e+00 1287.00
IUUC-Tsy-119552 Tarsius syrichta 93.20 0.00e+00 1213.00
IUUC-Tca-121616 Theobroma cacao 38.10 9.00e-31 129.00
IUUC-Tae-124768 Triticum aestivum 42.17 4.00e-30 126.00
IUUC-Tur-126480 Triticum urartu 42.17 2.00e-30 127.00
IUUC-Tbe-127902 Tupaia belangeri 94.03 0.00e+00 964.00
IUUC-Ttr-129278 Tursiops truncatus 93.07 0.00e+00 1174.00
IUUC-Vpa-130741 Vicugna pacos 88.25 0.00e+00 818.00
IUUC-Vvi-131437 Vitis vinifera 45.45 4.00e-29 123.00
IUUC-Xtr-132247 Xenopus tropicalis 64.71 0.00e+00 1300.00
IUUC-Xma-134277 Xiphophorus maculatus 62.21 0.00e+00 1345.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved