iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000138443.15	ENST00000295851.9	ENSP00000295851.4
ENSG00000138443.15	ENST00000261017.9	ENSP00000261017.5
ENSG00000138443.15	ENST00000447762.5	ENSP00000397850.1
ENSG00000138443.15	ENST00000416001.5	ENSP00000405801.1
ENSG00000138443.15	ENST00000430418.5	ENSP00000408898.1
ENSG00000138443.15	ENST00000425253.1	ENSP00000399040.1
ENSG00000138443.15	ENST00000413635.5	ENSP00000405255.1
ENSG00000138443.15	ENST00000424558.5	ENSP00000391433.1
ENSG00000138443.15	ENST00000431886.5	ENSP00000408334.1
ENSG00000138443.15	ENST00000444584.1	ENSP00000398487.1
ENSG00000138443.15	ENST00000422511.6	ENSP00000396249.2
ENSG00000138443.15	ENST00000441061.5	ENSP00000410509.2
ENSG00000138443.15	ENST00000451591.6	ENSP00000413375.2
ENSG00000138443.15	ENST00000454023.1	ENSP00000404352.1
ENSG00000138443.15	ENST00000261016.10	ENSP00000261016.7

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circBase	circRNADb
CircNet	miRTarBase	microRNA	TRANSFAC
miRWalk	TargetScan	RepTar	SomamiR
miRcode	RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
GWASdb	GWAS Central	OMIM
Post-translational Modifications (PTMs)
PHOSIDA	BioGRID
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.10e-15	56.6	453	508

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +ekv ++ydy+  ++deL++++G +++vi  +++d gW +g    +g  GlfP n+ve +
   Q: 453  LEKVVAIYDYTKDKEDELSFQEGAIIYVI--KKNDDGWYEG--VMNGVTGLFPGNYVESI 508
           589**************************..99********..7*************987 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MAELQMLLEE EIPGGRRALF DSYTNLERVA DYCENNYIQS ADKQRALEET KAYTTQSLAS 60
VAYLINTLAN NVLQMLDIQA SQLRRMESSI NHISQTVDIH KEKVARREIG ILTTNKNTSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGCGGCGC GGGCGAGGGT GGGAATCTTT TTCGGGCTCC CGGGGGCGGA GGGAAGGGAG 60
CGCGCGTGCG CGCGCCCGGC CGGCCGTCGC CGCGGTGACC GTCCTCGGAG TCCGTCGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR028457--ABI
IPR028456--ABI1/ABI2
IPR012849--Abl-interactor_HHR_dom
IPR001452--SH3_domain
IPR000727--T_SNARE_dom

PROSITE

PS50002--SH3
PS50192--T_SNARE

Pfam

PF07815--Abi_HHR
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0030296--F:protein tyrosine kinase activator activity
GO:0008154--P:actin polymerization or depolymerization

KEGG

hsa:10152

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001224	Ailuropoda melanoleuca	100.00	0.00e+00	742.00
IUUC-Apl-003871	Anas platyrhynchos	84.06	6.00e-173	600.00
IUUC-Aca-005006	Anolis carolinensis	97.93	4.00e-128	452.00
IUUC-Ame-010678	Astyanax mexicanus	93.39	7.00e-122	431.00
IUUC-Cel-018141	Caenorhabditis elegans	50.66	9.00e-41	161.00
IUUC-Cja-018977	Callithrix jacchus	99.81	0.00e+00	742.00
IUUC-Cfa-021021	Canis familiaris	92.80	0.00e+00	693.00
IUUC-Cpo-021598	Cavia porcellus	82.23	0.00e+00	664.00
IUUC-Dre-028600	Danio rerio	88.38	1.00e-111	397.00
IUUC-Dno-029514	Dasypus novemcinctus	92.62	0.00e+00	708.00
IUUC-Dor-030127	Dipodomys ordii	100.00	4.00e-73	268.00
IUUC-Dme-031578	Drosophila melanogaster	49.79	8.00e-52	197.00
IUUC-Eca-033764	Equus caballus	95.54	7.00e-98	351.00
IUUC-Eeu-035014	Erinaceus europaeus	93.57	0.00e+00	667.00
IUUC-Ggr-040119	Gaeumannomyces graminis	48.28	1.00e-11	65.90
IUUC-Gga-040772	Gallus gallus	98.76	5.00e-129	455.00
IUUC-Gac-041988	Gasterosteus aculeatus	59.74	3.00e-148	518.00
IUUC-Ggo-045101	Gorilla gorilla	99.03	0.00e+00	727.00
IUUC-Lch-050518	Latimeria chalumnae	95.07	3.00e-96	345.00
IUUC-Loc-052794	Lepisosteus oculatus	77.10	9.00e-132	463.00
IUUC-Lma-053273	Leptosphaeria maculans	48.28	3.00e-11	65.10
IUUC-Laf-053376	Loxodonta africana	100.00	0.00e+00	742.00
IUUC-Mcc-055805	Macaca mulatta	99.81	0.00e+00	730.00
IUUC-Meu-056378	Macropus eugenii	97.86	0.00e+00	720.00
IUUC-Mpo-057322	Magnaporthe poae	48.28	1.00e-11	65.90
IUUC-Mga-059638	Meleagris gallopavo	96.08	2.00e-99	356.00
IUUC-Mmr-060996	Microcebus murinus	99.61	0.00e+00	739.00
IUUC-Mdo-062105	Monodelphis domestica	88.07	0.00e+00	689.00
IUUC-Mmu-063681	Mus musculus	92.40	0.00e+00	775.00
IUUC-Mpu-066330	Mustela putorius furo	92.95	2.00e-162	565.00
IUUC-Mlu-066995	Myotis lucifugus	96.24	0.00e+00	640.00
IUUC-Ncr-068791	Neurospora crassa	54.72	9.00e-12	66.60
IUUC-Nle-069530	Nomascus leucogenys	97.23	1.00e-112	400.00
IUUC-Opr-071034	Ochotona princeps	95.70	2.00e-81	296.00
IUUC-Ont-072403	Oreochromis niloticus	89.71	6.00e-115	407.00
IUUC-Ocu-073957	Oryctolagus cuniculus	97.47	0.00e+00	719.00
IUUC-Oga-088726	Otolemur garnettii	99.50	7.00e-84	304.00
IUUC-Oar-090148	Ovis aries	96.47	1.00e-136	479.00
IUUC-Psi-093503	Pelodiscus sinensis	99.50	3.00e-105	375.00
IUUC-Pma-094641	Petromyzon marinus	74.76	7.00e-75	274.00
IUUC-Pfo-096081	Poecilia formosa	89.71	4.00e-116	411.00
IUUC-Pca-101039	Procavia capensis	97.18	5.00e-86	311.00
IUUC-Pva-102786	Pteropus vampyrus	84.80	0.00e+00	701.00
IUUC-Sar-113308	Sorex araneus	99.50	1.00e-105	376.00
IUUC-Tru-118501	Takifugu rubripes	86.89	1.00e-108	386.00
IUUC-Tsy-119355	Tarsius syrichta	98.95	0.00e+00	645.00
IUUC-Tni-120876	Tetraodon nigroviridis	86.07	8.00e-108	384.00
IUUC-Tre-121917	Trichoderma reesei	50.94	1.00e-11	65.90
IUUC-Tvi-122534	Trichoderma virens	50.94	2.00e-11	65.90
IUUC-Tbe-127781	Tupaia belangeri	88.76	1.00e-124	439.00
IUUC-Ttr-129223	Tursiops truncatus	92.41	2.00e-164	572.00
IUUC-Vpa-130597	Vicugna pacos	98.95	0.00e+00	639.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence