iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Mmu-063507

UUCD1 version

UUC-MuM-00245

Ensembl Protein ID

ENSMUSP00000100592.1

UniProt Accession

G3X9R7; Q8CGR1; Q9D3V4; RN148_MOUSE

Genbank Protein ID

AAN75221.1; BAB30557.1; EDL13833.1

Protein Name

RING finger protein 148; Goliath-related E3 ubiquitin-protein ligase 3

Genbank Nucleotide ID

AY155440; AK017027; AC155850

Gene Name

Rnf148; Greul3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000078179.1	ENSMUST00000104979.1	ENSMUSP00000100592.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	24527571

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	1.10e-05	26.9	269	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C++++  +d  ++l C+H+fh++C+  w         + +CP C+
   Q: 269  CVVCFDMYkaQDVIRILTCKHFFHKTCIDPW------LLAHRTCPMCK 310
           ********77666999***************......999*******6 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MLLCVSCLSV NGEMNPLGPT PSVHRSVSFW LLRLSVFLLL SLRDSKGKAI WTAHLNITFQ 60
VGNRIISELG ESGVFGNHSP LERVSGAVVL PEGWNQNACS PLTNFSRPDQ TDTWLALIER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAAGAAAGA AAAAGTACCA GGAGTAAAAA TGGTAGAATG AACAAGGTAT CTTTCATCTT 60
GGCAGACCTT CTTGATCTAT GTGCATTAGT CGTCTGCGCT TTGACAGCTC AAGCTAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding

KEGG

mmu:71300

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001306	Ailuropoda melanoleuca	91.48	1.00e-145	508.00
IUUC-Cpo-022417	Cavia porcellus	84.93	4.00e-142	497.00
IUUC-Csa-024009	Chlorocebus sabaeus	87.73	2.00e-147	514.00
IUUC-Dno-029641	Dasypus novemcinctus	85.40	5.00e-160	556.00
IUUC-Eca-033938	Equus caballus	86.75	2.00e-150	525.00
IUUC-Ggo-044884	Gorilla gorilla	82.57	5.00e-143	499.00
IUUC-Hsa-046561	Homo sapiens	81.58	7.00e-136	476.00
IUUC-Mdo-062912	Monodelphis domestica	81.48	1.00e-139	489.00
IUUC-Mlu-067519	Myotis lucifugus	83.12	4.00e-146	510.00
IUUC-Oga-089172	Otolemur garnettii	89.40	3.00e-155	540.00
IUUC-Oar-089296	Ovis aries	87.50	4.00e-148	517.00
IUUC-Rno-105562	Rattus norvegicus	92.06	3.00e-165	573.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence