iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002007

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01016911

Gene Name

UBE2M

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000007567.1	ENSAMET00000008303.1	ENSAMEP00000007972.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.60e-38	130.2	6	129

Active Site

Position(s)	Description	Evidence
75	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 12   dppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsves 100
           + p+++ ++++d +dl +++++i+ p++  Y+ g+F +++++ + YP +PPkvk++t ++hPn++ +G+vCl+il+  e+W+p+l+++s
   Q: 6    NLPKTCDISFSDPDDLLNFKLVIC-PDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILR--EDWKPVLTINS 91
           78999******************9.**************************************************9..*********** PP
   S: 101  vllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +++++q l+ epnpe+pln+eaae l++nr+ ++++v+
   Q: 92   IIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQ 129
           ************************************97 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

DINELNLPKT CDISFSDPDD LLNFKLVICP DEGFYKSGKF VFSFKVGQGY PHDPPKVKCE 60
TMVYHPNIDL EGNVCLNILR EDWKPVLTIN SIIYGLQYLF LEPNPEDPLN KEAAEVLQNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACATAAACG AGCTGAACCT GCCCAAGACG TGTGACATCA GCTTCTCAGA TCCAGACGAT 60
CTCCTCAACT TCAAGCTGGT TATCTGTCCT GATGAGGTAA GGGCACACTC AGTTGGACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0019788--F:NEDD8 transferase activity
GO:0018169--F:ribosomal S6-glutamic acid ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000196	Aegilops tauschii	65.07	4.00e-53	200.00
IUUC-Atr-003170	Amborella trichopoda	65.99	5.00e-56	210.00
IUUC-Aca-005037	Anolis carolinensis	97.28	2.00e-83	301.00
IUUC-Aly-006219	Arabidopsis lyrata	66.67	2.00e-56	211.00
IUUC-Ath-006876	Arabidopsis thaliana	65.99	2.00e-56	211.00
IUUC-Ago-007910	Ashbya gossypii	44.06	2.00e-33	135.00
IUUC-Acl-008364	Aspergillus clavatus	59.86	1.00e-51	195.00
IUUC-Afl-008463	Aspergillus flavus	62.59	1.00e-53	202.00
IUUC-Afu-008803	Aspergillus fumigatus	59.86	7.00e-52	196.00
IUUC-Ani-009422	Aspergillus nidulans	62.59	3.00e-54	204.00
IUUC-Ang-009728	Aspergillus niger	62.96	5.00e-50	189.00
IUUC-Aor-009962	Aspergillus oryzae	62.59	1.00e-53	202.00
IUUC-Ate-010430	Aspergillus terreus	58.97	3.00e-48	184.00
IUUC-Ame-011382	Astyanax mexicanus	92.52	5.00e-80	289.00
IUUC-Bgr-012306	Blumeria graminis	58.50	3.00e-50	191.00
IUUC-Bta-012818	Bos taurus	100.00	8.00e-86	308.00
IUUC-Bci-013626	Botrytis cinerea	59.18	1.00e-49	188.00
IUUC-Bdi-014528	Brachypodium distachyon	67.12	5.00e-56	210.00
IUUC-Bol-015241	Brassica oleracea	65.99	1.00e-56	211.00
IUUC-Bra-017425	Brassica rapa	65.99	1.00e-56	211.00
IUUC-Cja-019213	Callithrix jacchus	100.00	3.00e-85	307.00
IUUC-Cfa-020242	Canis familiaris	100.00	1.00e-85	308.00
IUUC-Cpo-022405	Cavia porcellus	94.56	1.00e-79	288.00
IUUC-Cre-022865	Chlamydomonas reinhardtii	64.03	2.00e-47	181.00
IUUC-Csa-023269	Chlorocebus sabaeus	100.00	8.00e-86	308.00
IUUC-Cin-025333	Ciona intestinalis	78.23	6.00e-68	249.00
IUUC-Csv-025898	Ciona savignyi	79.43	2.00e-66	244.00
IUUC-Cgl-026477	Colletotrichum gloeosporioides	59.18	2.00e-51	194.00
IUUC-Cne-027097	Cryptococcus neoformans	63.01	3.00e-53	200.00
IUUC-Cme-027287	Cyanidioschyzon merolae	48.05	3.00e-18	84.70
IUUC-Dre-028514	Danio rerio	92.52	2.00e-79	287.00
IUUC-Dno-029678	Dasypus novemcinctus	100.00	9.00e-85	305.00
IUUC-Dor-030851	Dipodomys ordii	63.27	3.00e-45	174.00
IUUC-Dse-031265	Dothistroma septosporum	58.50	3.00e-51	194.00
IUUC-Dme-032076	Drosophila melanogaster	76.71	1.00e-66	245.00
IUUC-Ete-032350	Echinops telfairi	73.04	2.00e-43	166.00
IUUC-Eca-034075	Equus caballus	100.00	1.00e-85	308.00
IUUC-Fca-035654	Felis catus	100.00	2.00e-84	303.00
IUUC-Fal-037283	Ficedula albicollis	91.14	4.00e-39	152.00
IUUC-Fox-037877	Fusarium oxysporum	59.18	2.00e-51	194.00
IUUC-Fso-038428	Fusarium solani	59.18	1.00e-51	195.00
IUUC-Gmo-039402	Gadus morhua	91.84	1.00e-79	288.00
IUUC-Ggr-039731	Gaeumannomyces graminis	61.90	3.00e-52	197.00
IUUC-Gga-041122	Gallus gallus	86.71	6.00e-72	263.00
IUUC-Gma-043805	Glycine max	64.63	6.00e-55	206.00
IUUC-Ggo-044436	Gorilla gorilla	100.00	8.00e-86	308.00
IUUC-Hsa-046026	Homo sapiens	100.00	8.00e-86	308.00
IUUC-Hvu-047056	Hordeum vulgare	65.07	3.00e-53	201.00
IUUC-Itr-047889	Ictidomys tridecemlineatus	100.00	8.00e-86	308.00
IUUC-Kpa-049315	Komagataella pastoris	53.15	1.00e-42	165.00
IUUC-Lch-050360	Latimeria chalumnae	85.34	5.00e-55	207.00
IUUC-Lpe-050743	Leersia perrieri	66.67	5.00e-53	200.00
IUUC-Lma-053001	Leptosphaeria maculans	62.59	3.00e-53	200.00
IUUC-Laf-053463	Loxodonta africana	99.32	6.00e-84	301.00
IUUC-Mcc-054966	Macaca mulatta	100.00	6.00e-43	165.00
IUUC-Meu-056085	Macropus eugenii	97.26	1.00e-81	294.00
IUUC-Mor-057250	Magnaporthe oryzae	61.22	3.00e-52	197.00
IUUC-Mpo-057481	Magnaporthe poae	62.59	5.00e-52	196.00
IUUC-Mtr-058251	Medicago truncatula	64.63	2.00e-55	207.00
IUUC-Mla-059119	Melampsora laricipopulina	61.90	9.00e-52	196.00
IUUC-Mga-059881	Meleagris gallopavo	93.07	8.00e-53	197.00
IUUC-Mvi-060449	Microbotryum violaceum	63.64	2.00e-54	204.00
IUUC-Mmr-061511	Microcebus murinus	100.00	4.00e-43	165.00
IUUC-Mmu-063962	Mus musculus	100.00	8.00e-86	308.00
IUUC-Mac-064967	Musa acuminata	67.35	5.00e-57	214.00
IUUC-Mlu-066955	Myotis lucifugus	100.00	3.00e-84	303.00
IUUC-Nfi-068300	Neosartorya fischeri	59.86	7.00e-52	196.00
IUUC-Ncr-068944	Neurospora crassa	59.18	1.00e-50	192.00
IUUC-Nle-069051	Nomascus leucogenys	100.00	2.00e-84	303.00
IUUC-Opr-070635	Ochotona princeps	100.00	9.00e-84	301.00
IUUC-Ont-072348	Oreochromis niloticus	91.16	4.00e-79	286.00
IUUC-Ocu-074905	Oryctolagus cuniculus	100.00	8.00e-86	308.00
IUUC-Oba-075825	Oryza barthii	67.12	3.00e-57	214.00
IUUC-Obr-076067	Oryza brachyantha	66.44	7.00e-57	213.00
IUUC-Ogl-077594	Oryza glaberrima	67.12	3.00e-57	214.00
IUUC-Ogu-078073	Oryza glumaepatula	67.12	3.00e-57	214.00
IUUC-Oin-080060	Oryza indica	66.67	4.00e-57	215.00
IUUC-Olo-080314	Oryza longistaminata	67.12	1.00e-57	215.00
IUUC-Ome-081713	Oryza meridionalis	67.12	3.00e-57	214.00
IUUC-Oni-082426	Oryza nivara	67.12	3.00e-57	214.00
IUUC-Opu-083942	Oryza punctata	67.88	1.00e-53	202.00
IUUC-Oru-085104	Oryza rufipogon	67.12	3.00e-57	214.00
IUUC-Osa-086168	Oryza sativa	67.12	3.00e-57	214.00
IUUC-Olu-087854	Ostreococcus lucimarinus	62.84	2.00e-52	197.00
IUUC-Oga-088580	Otolemur garnettii	100.00	8.00e-86	308.00
IUUC-Oar-089623	Ovis aries	93.24	1.00e-76	278.00
IUUC-Ptr-091020	Pan troglodytes	100.00	9.00e-84	301.00
IUUC-Pan-092119	Papio anubis	100.00	2.00e-84	303.00
IUUC-Psi-093494	Pelodiscus sinensis	97.28	5.00e-82	295.00
IUUC-Pno-094972	Phaeosphaeria nodorum	59.35	4.00e-51	193.00
IUUC-Ppa-095187	Physcomitrella patens	72.11	1.00e-60	225.00
IUUC-Pfo-097205	Poecilia formosa	91.84	4.00e-79	286.00
IUUC-Pab-098434	Pongo abelii	100.00	8.00e-86	308.00
IUUC-Pop-099789	Populus trichocarpa	65.99	2.00e-56	211.00
IUUC-Pca-100300	Procavia capensis	99.32	3.00e-83	299.00
IUUC-Ppe-101143	Prunus persica	65.99	3.00e-56	211.00
IUUC-Pva-102143	Pteropus vampyrus	100.00	8.00e-86	308.00
IUUC-Pgr-103675	Puccinia graminis	62.24	1.00e-50	192.00
IUUC-Ptt-103997	Puccinia triticina	64.08	1.00e-51	195.00
IUUC-Pte-104042	Pyrenophora teres	61.90	7.00e-53	199.00
IUUC-Pyt-104616	Pyrenophora triticirepentis	61.90	2.00e-52	197.00
IUUC-Rno-105107	Rattus norvegicus	100.00	8.00e-86	308.00
IUUC-Sce-106385	Saccharomyces cerevisiae	43.79	1.00e-33	135.00
IUUC-Sha-106899	Sarcophilus harrisii	97.28	5.00e-82	296.00
IUUC-Sja-107789	Schizosaccharomyces japonicus	54.79	9.00e-45	172.00
IUUC-Spo-108143	Schizosaccharomyces pombe	53.42	6.00e-44	169.00
IUUC-Ssl-108427	Sclerotinia sclerotiorum	59.18	2.00e-49	188.00
IUUC-Smo-109330	Selaginella moellendorffii	68.71	2.00e-58	218.00
IUUC-Sit-109702	Setaria italica	67.81	4.00e-57	213.00
IUUC-Sly-111650	Solanum lycopersicum	68.71	4.00e-58	216.00
IUUC-Stu-112655	Solanum tuberosum	68.03	2.00e-58	218.00
IUUC-Sar-113632	Sorex araneus	99.32	7.00e-85	305.00
IUUC-Sbi-114357	Sorghum bicolor	68.49	6.00e-58	216.00
IUUC-Sre-114912	Sporisorium reilianum	63.01	4.00e-54	203.00
IUUC-Tsy-119639	Tarsius syrichta	98.77	5.00e-45	172.00
IUUC-Tni-119674	Tetraodon nigroviridis	93.97	3.00e-63	233.00
IUUC-Tca-121359	Theobroma cacao	68.03	3.00e-57	214.00
IUUC-Tre-122115	Trichoderma reesei	58.50	2.00e-50	191.00
IUUC-Tvi-122656	Trichoderma virens	58.50	5.00e-50	190.00
IUUC-Tae-124489	Triticum aestivum	65.07	3.00e-53	201.00
IUUC-Tur-126125	Triticum urartu	65.07	2.00e-53	202.00
IUUC-Tme-126950	Tuber melanosporum	61.90	9.00e-53	199.00
IUUC-Tbe-127874	Tupaia belangeri	93.14	2.00e-51	194.00
IUUC-Ttr-128213	Tursiops truncatus	99.27	4.00e-77	279.00
IUUC-Uma-129329	Ustilago maydis	62.76	5.00e-54	203.00
IUUC-Vda-129754	Verticillium dahliae	61.22	5.00e-52	196.00
IUUC-Vvi-131182	Vitis vinifera	67.35	4.00e-56	210.00
IUUC-Xtr-132742	Xenopus tropicalis	97.28	2.00e-83	300.00
IUUC-Xma-133558	Xiphophorus maculatus	91.84	4.00e-79	286.00
IUUC-Yli-134467	Yarrowia lipolytica	58.22	1.00e-49	188.00
IUUC-Zma-134838	Zea mays	67.57	2.00e-57	216.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence