iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097379

Ensembl Protein ID

ENSPFOP00000023600.1

UniProt Accession

A0A096LWQ9; A0A096LWQ9_POEFO

Genbank Protein ID

ENSPFOP00000023600

Protein Name

Estrogen receptor; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1

Genbank Nucleotide ID

AYCK01000301

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000019595.2	ENSPFOT00000019742.2	ENSPFOP00000019719.2
ENSPFOG00000019595.2	ENSPFOT00000024111.1	ENSPFOP00000023600.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UMI	56.75	1.00e-131	468.00	IUUC-Hsa-046944

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Poecilia formosa

Functional Description
(View)

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Protein Sequence
(Fasta)

MYKRQNPVQS KQEFGPALRP RISPASSELE TLSSPRLPPS PRAPLSDMYP EESRGSGGVA 60
AVDFLEGTYD YATPTPAPTP LYSHSTTGYF SAPLDAQGPP SDGSLHSLGS GPTSPLVFVP 120

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Nucleotide Sequence
(Fasta)

CAGAATGAGA TTTGACCTCC GGTTTTGTTT GCCGTGTTAT GGTGACCTGG CTCTTAAACA 60
CACCACACTT ATTGATTTGG CTGCATCTTT AATTTGTTTA TCCTTTTTTA AACCTTTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0446--Lipid-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0754--Steroid-binding
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR024178--Oest_rcpt/oest-rel_rcp
IPR001292--Oestr_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF02159--Oest_recep
PF00105--zf-C4

PRINTS

PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005634--C:nucleus
GO:0030284--F:estrogen receptor activity
GO:0043565--F:sequence-specific DNA binding
GO:0005496--F:steroid binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001925	Ailuropoda melanoleuca	63.66	4.00e-128	451.00
IUUC-Apl-003688	Anas platyrhynchos	54.32	3.00e-137	482.00
IUUC-Aca-005222	Anolis carolinensis	50.00	3.00e-140	492.00
IUUC-Ame-010731	Astyanax mexicanus	63.33	1.00e-165	576.00
IUUC-Bta-013112	Bos taurus	49.73	2.00e-131	462.00
IUUC-Cja-019408	Callithrix jacchus	57.68	2.00e-130	459.00
IUUC-Cfa-020694	Canis familiaris	50.68	1.00e-131	463.00
IUUC-Cpo-021426	Cavia porcellus	50.35	4.00e-129	455.00
IUUC-Csa-023736	Chlorocebus sabaeus	56.60	5.00e-132	464.00
IUUC-Dre-027698	Danio rerio	61.42	6.00e-169	587.00
IUUC-Dno-029477	Dasypus novemcinctus	59.86	5.00e-128	451.00
IUUC-Dor-030572	Dipodomys ordii	59.85	9.00e-125	440.00
IUUC-Ete-032849	Echinops telfairi	45.01	4.00e-87	315.00
IUUC-Eca-033605	Equus caballus	49.36	1.00e-131	463.00
IUUC-Eeu-034683	Erinaceus europaeus	53.81	4.00e-54	205.00
IUUC-Fca-035928	Felis catus	61.61	1.00e-127	449.00
IUUC-Fal-036754	Ficedula albicollis	54.86	1.00e-147	516.00
IUUC-Gmo-038872	Gadus morhua	72.92	5.00e-162	563.00
IUUC-Gga-040988	Gallus gallus	54.86	2.00e-144	506.00
IUUC-Gac-042015	Gasterosteus aculeatus	74.76	0.00e+00	741.00
IUUC-Ggo-044749	Gorilla gorilla	58.30	1.00e-130	460.00
IUUC-Hsa-046944	Homo sapiens	60.38	6.00e-132	464.00
IUUC-Itr-048863	Ictidomys tridecemlineatus	49.82	4.00e-130	458.00
IUUC-Loc-052414	Lepisosteus oculatus	65.26	0.00e+00	649.00
IUUC-Mcc-054781	Macaca mulatta	60.38	1.00e-130	460.00
IUUC-Meu-056232	Macropus eugenii	50.90	4.00e-131	461.00
IUUC-Mga-059319	Meleagris gallopavo	54.68	7.00e-144	504.00
IUUC-Mmr-061636	Microcebus murinus	53.31	1.00e-56	213.00
IUUC-Mdo-062661	Monodelphis domestica	51.08	2.00e-132	466.00
IUUC-Mmu-063330	Mus musculus	51.89	2.00e-129	456.00
IUUC-Mpu-065757	Mustela putorius furo	50.00	1.00e-132	467.00
IUUC-Mlu-067712	Myotis lucifugus	59.95	7.00e-130	457.00
IUUC-Nle-069283	Nomascus leucogenys	57.68	4.00e-130	458.00
IUUC-Opr-070391	Ochotona princeps	58.78	6.00e-128	451.00
IUUC-Ont-071369	Oreochromis niloticus	76.06	0.00e+00	762.00
IUUC-Oan-073734	Ornithorhynchus anatinus	41.62	4.00e-57	214.00
IUUC-Ocu-074292	Oryctolagus cuniculus	53.11	8.00e-133	467.00
IUUC-Ola-087052	Oryzias latipes	82.82	0.00e+00	826.00
IUUC-Oga-088586	Otolemur garnettii	52.33	1.00e-128	454.00
IUUC-Oar-090156	Ovis aries	56.09	4.00e-128	451.00
IUUC-Ptr-091321	Pan troglodytes	60.38	1.00e-130	460.00
IUUC-Pan-092851	Papio anubis	59.95	1.00e-130	460.00
IUUC-Psi-093434	Pelodiscus sinensis	53.79	2.00e-142	499.00
IUUC-Pab-097735	Pongo abelii	60.38	1.00e-130	460.00
IUUC-Pva-102125	Pteropus vampyrus	52.47	3.00e-132	465.00
IUUC-Rno-106121	Rattus norvegicus	51.09	1.00e-130	460.00
IUUC-Sha-107547	Sarcophilus harrisii	50.54	7.00e-131	461.00
IUUC-Sar-113650	Sorex araneus	44.61	3.00e-76	278.00
IUUC-Tgu-117175	Taeniopygia guttata	54.50	2.00e-146	512.00
IUUC-Tru-117545	Takifugu rubripes	77.98	0.00e+00	779.00
IUUC-Tsy-119586	Tarsius syrichta	51.99	3.00e-109	389.00
IUUC-Tni-120121	Tetraodon nigroviridis	69.57	0.00e+00	772.00
IUUC-Tbe-127548	Tupaia belangeri	54.43	1.00e-100	360.00
IUUC-Ttr-128374	Tursiops truncatus	48.66	3.00e-117	415.00
IUUC-Vpa-130464	Vicugna pacos	50.76	2.00e-82	300.00
IUUC-Xtr-132171	Xenopus tropicalis	53.56	1.00e-134	473.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence