iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062666

UUCD1 version

UUC-MoD-00644

Ensembl Protein ID

ENSMODP00000025376.2

UniProt Accession

F7C0E8; F7C0E8_MONDO

Protein Name

Uncharacterized protein

Gene Name

FBXO4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000020286.3	ENSMODT00000025827.3	ENSMODP00000025376.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	75.68	4.00e-157	551.00	IUUC-Hsa-046558

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAEREPSSSS PGTSPTPLSE RSRLEAAILS GWRSFWQSVG KERPGPCARP ADEEEASALT 60
SLPIYVQLYI MSFLSPHDLY QLGSTSRYWN VTVRDPMLWK FFLLRDIPSW TSVDWKSLPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGA GGGAGCCCAG CTCCAGCAGC CCCGGGACGT CCCCGACGCC CCTCAGTGAA 60
CGTAGCCGCC TAGAGGCAGC GATCCTGAGC GGCTGGAGGA GCTTCTGGCA GTCAGTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0007568--P:aging
GO:0019725--P:cellular homeostasis
GO:0071479--P:cellular response to ionizing radiation
GO:0035726--P:common myeloid progenitor cell proliferation
GO:0048147--P:negative regulation of fibroblast proliferation
GO:1900181--P:negative regulation of protein localization to nucleus
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:2000001--P:regulation of DNA damage checkpoint
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

mdo:100018021

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001232	Ailuropoda melanoleuca	77.93	2.00e-158	551.00
IUUC-Apl-004129	Anas platyrhynchos	61.59	3.00e-99	354.00
IUUC-Aca-005076	Anolis carolinensis	51.99	5.00e-96	344.00
IUUC-Ame-011122	Astyanax mexicanus	48.43	2.00e-78	286.00
IUUC-Bta-012449	Bos taurus	76.76	2.00e-153	535.00
IUUC-Bol-015278	Brassica oleracea	38.46	1.00e-03	37.70
IUUC-Cja-019890	Callithrix jacchus	76.01	9.00e-155	539.00
IUUC-Cfa-021134	Canis familiaris	78.11	6.00e-155	540.00
IUUC-Cpo-021693	Cavia porcellus	76.85	2.00e-138	484.00
IUUC-Csa-023540	Chlorocebus sabaeus	75.74	1.00e-152	532.00
IUUC-Dre-028667	Danio rerio	48.20	1.00e-81	296.00
IUUC-Dno-028997	Dasypus novemcinctus	76.23	1.00e-155	542.00
IUUC-Dor-030135	Dipodomys ordii	69.21	3.00e-125	441.00
IUUC-Ete-033149	Echinops telfairi	71.66	2.00e-147	514.00
IUUC-Eca-033292	Equus caballus	76.85	5.00e-138	483.00
IUUC-Eeu-034504	Erinaceus europaeus	61.80	3.00e-100	358.00
IUUC-Fca-036476	Felis catus	78.38	8.00e-166	576.00
IUUC-Fal-036711	Ficedula albicollis	63.44	8.00e-115	406.00
IUUC-Gmo-039592	Gadus morhua	47.08	8.00e-77	280.00
IUUC-Gga-040924	Gallus gallus	63.89	1.00e-116	412.00
IUUC-Gac-041791	Gasterosteus aculeatus	46.99	2.00e-77	282.00
IUUC-Ggo-044736	Gorilla gorilla	74.66	2.00e-150	525.00
IUUC-Hsa-046558	Homo sapiens	74.93	2.00e-151	528.00
IUUC-Itr-048956	Ictidomys tridecemlineatus	77.60	3.00e-155	541.00
IUUC-Lch-049817	Latimeria chalumnae	62.88	1.00e-115	409.00
IUUC-Loc-052226	Lepisosteus oculatus	50.13	5.00e-95	341.00
IUUC-Laf-054371	Loxodonta africana	76.76	5.00e-153	533.00
IUUC-Mcc-054904	Macaca mulatta	75.47	4.00e-152	530.00
IUUC-Meu-056192	Macropus eugenii	67.28	7.00e-109	386.00
IUUC-Mmr-061692	Microcebus murinus	75.41	2.00e-153	535.00
IUUC-Mmu-064223	Mus musculus	74.05	3.00e-157	547.00
IUUC-Mpu-066290	Mustela putorius furo	77.84	1.00e-153	536.00
IUUC-Mlu-067882	Myotis lucifugus	75.88	8.00e-154	536.00
IUUC-Nle-070162	Nomascus leucogenys	75.20	4.00e-152	530.00
IUUC-Opr-070789	Ochotona princeps	73.72	4.00e-58	218.00
IUUC-Ont-071690	Oreochromis niloticus	47.58	3.00e-75	275.00
IUUC-Oan-072928	Ornithorhynchus anatinus	75.63	1.00e-101	362.00
IUUC-Ocu-073857	Oryctolagus cuniculus	76.23	3.00e-149	521.00
IUUC-Ola-086607	Oryzias latipes	45.65	4.00e-81	295.00
IUUC-Oga-088929	Otolemur garnettii	75.96	6.00e-149	520.00
IUUC-Oar-089305	Ovis aries	79.01	8.00e-143	499.00
IUUC-Ptr-090813	Pan troglodytes	71.16	5.00e-140	490.00
IUUC-Pan-092924	Papio anubis	73.33	3.00e-139	488.00
IUUC-Psi-093237	Pelodiscus sinensis	65.76	1.00e-123	436.00
IUUC-Pfo-096259	Poecilia formosa	46.46	9.00e-79	286.00
IUUC-Pab-098292	Pongo abelii	75.47	7.00e-153	533.00
IUUC-Pva-102221	Pteropus vampyrus	77.30	4.00e-158	550.00
IUUC-Rno-105910	Rattus norvegicus	75.68	9.00e-161	559.00
IUUC-Sha-106998	Sarcophilus harrisii	87.60	0.00e+00	646.00
IUUC-Sar-113033	Sorex araneus	70.27	1.00e-140	492.00
IUUC-Ssc-115507	Sus scrofa	76.22	8.00e-145	506.00
IUUC-Tgu-116502	Taeniopygia guttata	63.03	1.00e-112	399.00
IUUC-Tru-118203	Takifugu rubripes	47.06	1.00e-70	260.00
IUUC-Tni-120249	Tetraodon nigroviridis	46.40	5.00e-74	271.00
IUUC-Tur-126361	Triticum urartu	25.00	1.40e-02	33.50
IUUC-Tbe-128100	Tupaia belangeri	60.24	4.00e-96	344.00
IUUC-Ttr-128299	Tursiops truncatus	78.70	3.00e-141	494.00
IUUC-Vpa-130394	Vicugna pacos	66.67	8.00e-123	433.00
IUUC-Xtr-131825	Xenopus tropicalis	53.08	4.00e-106	378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence