iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074634

Ensembl Protein ID

ENSOCUP00000008068.3

UniProt Accession

G1SX18; G1SX18_RABIT

Protein Name

Uncharacterized protein

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000009353.3	ENSOCUT00000009352.3	ENSOCUP00000008068.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	85.88	0.00e+00	842.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MVDTGSPLCV LSALDADDLE SPLSEEFLQE MGNIHEISQS IGEDSSGSFS FPEYQCLGSC 60
SGSDGSVITD TLSPASSPSS VTCPVVPGGV DEYPSGALNI ECRICGDRAS GYHYGVHACE 120

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Nucleotide Sequence
(Fasta)

GACCATAATG CGGGGACGTC GGTGCGCTGT GGAGTTCGAG TGTCACAGAG CTGGGGGCGT 60
TTTCGAGACC CCCAGGGACC CCCGAGGCTA GGTAACTCGT GTCCCGGACA GACTCTCGGC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	82.97	0.00e+00	849.00
IUUC-Apl-003330	Anas platyrhynchos	78.11	0.00e+00	783.00
IUUC-Aca-004598	Anolis carolinensis	76.34	0.00e+00	762.00
IUUC-Acl-008339	Aspergillus clavatus	48.48	7.80e-02	30.40
IUUC-Ame-011508	Astyanax mexicanus	66.93	0.00e+00	665.00
IUUC-Bta-012621	Bos taurus	83.50	0.00e+00	821.00
IUUC-Cja-019688	Callithrix jacchus	85.49	0.00e+00	833.00
IUUC-Cfa-020859	Canis familiaris	84.49	0.00e+00	863.00
IUUC-Cpo-021607	Cavia porcellus	81.31	0.00e+00	798.00
IUUC-Csa-023313	Chlorocebus sabaeus	85.49	0.00e+00	835.00
IUUC-Cho-024741	Choloepus hoffmanni	74.16	0.00e+00	688.00
IUUC-Dre-027446	Danio rerio	65.29	0.00e+00	643.00
IUUC-Dno-029173	Dasypus novemcinctus	83.70	0.00e+00	818.00
IUUC-Dor-030581	Dipodomys ordii	83.47	0.00e+00	776.00
IUUC-Ete-032330	Echinops telfairi	80.12	0.00e+00	814.00
IUUC-Eca-033712	Equus caballus	83.70	0.00e+00	811.00
IUUC-Fca-036555	Felis catus	84.16	0.00e+00	857.00
IUUC-Fal-036677	Ficedula albicollis	77.73	0.00e+00	781.00
IUUC-Gmo-039240	Gadus morhua	73.35	5.00e-177	613.00
IUUC-Gga-040473	Gallus gallus	78.33	0.00e+00	785.00
IUUC-Gac-041872	Gasterosteus aculeatus	64.76	0.00e+00	659.00
IUUC-Ggo-045226	Gorilla gorilla	85.88	0.00e+00	839.00
IUUC-Hsa-046893	Homo sapiens	85.88	0.00e+00	839.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	84.49	0.00e+00	823.00
IUUC-Lch-050116	Latimeria chalumnae	71.17	0.00e+00	723.00
IUUC-Loc-052131	Lepisosteus oculatus	74.25	0.00e+00	649.00
IUUC-Laf-054323	Loxodonta africana	83.30	0.00e+00	821.00
IUUC-Mcc-054841	Macaca mulatta	85.88	0.00e+00	836.00
IUUC-Meu-056833	Macropus eugenii	73.36	0.00e+00	697.00
IUUC-Mga-059995	Meleagris gallopavo	71.20	0.00e+00	696.00
IUUC-Mdo-061954	Monodelphis domestica	79.63	0.00e+00	722.00
IUUC-Mmu-064295	Mus musculus	84.10	0.00e+00	796.00
IUUC-Mpu-066216	Mustela putorius furo	83.50	0.00e+00	853.00
IUUC-Nle-069970	Nomascus leucogenys	85.69	0.00e+00	837.00
IUUC-Ont-071594	Oreochromis niloticus	65.55	0.00e+00	657.00
IUUC-Oan-073501	Ornithorhynchus anatinus	80.54	0.00e+00	711.00
IUUC-Oni-082926	Oryza nivara	29.41	2.30e-02	29.60
IUUC-Ola-086585	Oryzias latipes	71.29	2.00e-174	604.00
IUUC-Oga-088738	Otolemur garnettii	84.69	0.00e+00	822.00
IUUC-Oar-090453	Ovis aries	83.10	0.00e+00	818.00
IUUC-Ptr-091518	Pan troglodytes	85.69	0.00e+00	833.00
IUUC-Pan-092006	Papio anubis	85.69	0.00e+00	833.00
IUUC-Psi-093352	Pelodiscus sinensis	76.92	0.00e+00	783.00
IUUC-Pfo-096060	Poecilia formosa	66.93	0.00e+00	660.00
IUUC-Pab-098602	Pongo abelii	79.96	0.00e+00	736.00
IUUC-Rno-105283	Rattus norvegicus	84.29	0.00e+00	797.00
IUUC-Sha-106560	Sarcophilus harrisii	81.71	0.00e+00	806.00
IUUC-Ssc-115266	Sus scrofa	83.30	0.00e+00	857.00
IUUC-Tgu-116778	Taeniopygia guttata	77.34	0.00e+00	778.00
IUUC-Tru-118436	Takifugu rubripes	64.37	0.00e+00	647.00
IUUC-Tsy-119642	Tarsius syrichta	96.54	6.00e-132	464.00
IUUC-Tni-119859	Tetraodon nigroviridis	64.57	0.00e+00	644.00
IUUC-Tbe-127464	Tupaia belangeri	82.50	0.00e+00	850.00
IUUC-Ttr-129307	Tursiops truncatus	79.96	0.00e+00	768.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence