iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116544

Ensembl Protein ID

ENSTGUP00000001825.1

UniProt Accession

H0YU57; H0YU57_TAEGU

Genbank Protein ID

ENSTGUP00000001825

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01020643

Gene Name

VCP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000001760.1	ENSTGUT00000001842.1	ENSTGUP00000001825.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	95.88	0.00e+00	1394.00	IUUC-Hsa-046162
UBD/Other/Other	67.87	0.00e+00	1018.00	IUUC-Sce-106244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

SKADDLSTAI LKQKNRPNRL IVDEAINEDN SVVSLSQAKM DELQLFRGDT VLLKGKKRRE 60
AVCIVLSDDT CSDEKIRMNR VVRNNLRVRL GDVISIQPCP DVKYGKRIHV LPIDDTVEGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTAAAGCCG ATGACTTATC GACTGCTATT CTGAAGCAGA AGAACAGGCC CAATCGGTTA 60
ATTGTTGATG AAGCTATCAA TGAAGACAAC AGTGTTGTGT CACTGTCCCA GGTGCGTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR003593--AAA+_ATPase
IPR005938--AAA_ATPase_CDC48
IPR009010--Asp_de-COase-like_dom
IPR003959--ATPase_AAA_core
IPR003960--ATPase_AAA_CS
IPR004201--Cdc48_dom2
IPR029067--CDC48_domain_2-like
IPR003338--CDC4_N-term_subdom
IPR027417--P-loop_NTPase
IPR015415--Vps4_C

PROSITE

PS00674--AAA

Pfam

PF00004--AAA
PF02933--CDC48_2
PF02359--CDC48_N
PF09336--Vps4_C

SMART

SM00382--AAA
SM01072--CDC48_2
SM01073--CDC48_N

Gene Ontology

GO:0005829--C:cytosol
GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0070062--C:extracellular exosome
GO:0005811--C:lipid particle
GO:0043209--C:myelin sheath
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000502--C:proteasome complex
GO:0035861--C:site of double-strand break
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1990730--C:VCP-NSFL1C complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0035800--F:deubiquitinase activator activity
GO:0003723--F:RNA binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070842--P:aggresome assembly
GO:0046034--P:ATP metabolic process
GO:0097352--P:autophagosome maturation
GO:0006302--P:double-strand break repair
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0072389--P:flavin adenine dinucleotide catabolic process
GO:0006734--P:NADH metabolic process
GO:2001171--P:positive regulation of ATP biosynthetic process
GO:1903007--P:positive regulation of Lys63-specific deubiquitinase activity
GO:0010918--P:positive regulation of mitochondrial membrane potential
GO:1903862--P:positive regulation of oxidative phosphorylation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0034214--P:protein hexamerization
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0016567--P:protein ubiquitination
GO:1903715--P:regulation of aerobic respiration
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0019985--P:translesion synthesis
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0019079--P:viral genome replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000524	Aegilops tauschii	77.85	0.00e+00	1160.00
IUUC-Aml-001849	Ailuropoda melanoleuca	95.76	0.00e+00	1416.00
IUUC-Atr-002619	Amborella trichopoda	75.66	0.00e+00	1188.00
IUUC-Apl-004070	Anas platyrhynchos	96.51	0.00e+00	1412.00
IUUC-Aca-004847	Anolis carolinensis	94.39	0.00e+00	1408.00
IUUC-Aly-005406	Arabidopsis lyrata	76.84	0.00e+00	1183.00
IUUC-Ath-006796	Arabidopsis thaliana	77.49	0.00e+00	1170.00
IUUC-Ago-008001	Ashbya gossypii	68.77	0.00e+00	989.00
IUUC-Acl-008066	Aspergillus clavatus	70.66	0.00e+00	1036.00
IUUC-Afl-008505	Aspergillus flavus	68.78	0.00e+00	1060.00
IUUC-Afu-008840	Aspergillus fumigatus	71.05	0.00e+00	1060.00
IUUC-Ani-009368	Aspergillus nidulans	68.83	0.00e+00	1066.00
IUUC-Ang-009724	Aspergillus niger	68.99	0.00e+00	1063.00
IUUC-Aor-010204	Aspergillus oryzae	68.78	0.00e+00	1060.00
IUUC-Ate-010370	Aspergillus terreus	69.28	0.00e+00	1064.00
IUUC-Ame-011388	Astyanax mexicanus	93.88	0.00e+00	1363.00
IUUC-Bgr-012223	Blumeria graminis	69.24	0.00e+00	1076.00
IUUC-Bta-013188	Bos taurus	95.76	0.00e+00	1415.00
IUUC-Bci-013831	Botrytis cinerea	70.26	0.00e+00	1060.00
IUUC-Bdi-014967	Brachypodium distachyon	78.24	0.00e+00	1182.00
IUUC-Bol-016113	Brassica oleracea	77.46	0.00e+00	1170.00
IUUC-Bra-017796	Brassica rapa	77.46	0.00e+00	1172.00
IUUC-Cel-018243	Caenorhabditis elegans	75.16	0.00e+00	1145.00
IUUC-Cja-019904	Callithrix jacchus	95.13	0.00e+00	1366.00
IUUC-Cfa-020304	Canis familiaris	95.76	0.00e+00	1414.00
IUUC-Cpo-021518	Cavia porcellus	95.88	0.00e+00	1410.00
IUUC-Cre-022719	Chlamydomonas reinhardtii	77.17	0.00e+00	1164.00
IUUC-Csa-023444	Chlorocebus sabaeus	95.88	0.00e+00	1412.00
IUUC-Cho-024482	Choloepus hoffmanni	94.51	0.00e+00	1384.00
IUUC-Cin-025517	Ciona intestinalis	83.09	0.00e+00	1211.00
IUUC-Csv-026060	Ciona savignyi	83.51	0.00e+00	1261.00
IUUC-Cgl-026690	Colletotrichum gloeosporioides	70.27	0.00e+00	1091.00
IUUC-Cne-026910	Cryptococcus neoformans	69.76	0.00e+00	1106.00
IUUC-Cme-027145	Cyanidioschyzon merolae	73.34	0.00e+00	1105.00
IUUC-Dre-028487	Danio rerio	94.01	0.00e+00	1364.00
IUUC-Dno-029257	Dasypus novemcinctus	95.88	0.00e+00	1412.00
IUUC-Dor-030473	Dipodomys ordii	94.26	0.00e+00	1363.00
IUUC-Dse-031319	Dothistroma septosporum	68.59	0.00e+00	1032.00
IUUC-Dme-032203	Drosophila melanogaster	80.00	0.00e+00	1211.00
IUUC-Eca-033311	Equus caballus	95.13	0.00e+00	1399.00
IUUC-Eeu-035293	Erinaceus europaeus	92.37	0.00e+00	691.00
IUUC-Fca-036097	Felis catus	96.15	0.00e+00	1322.00
IUUC-Fal-037292	Ficedula albicollis	96.75	0.00e+00	1416.00
IUUC-Fox-037827	Fusarium oxysporum	70.88	0.00e+00	1088.00
IUUC-Fso-038226	Fusarium solani	70.87	0.00e+00	1096.00
IUUC-Gmo-039157	Gadus morhua	86.27	0.00e+00	1242.00
IUUC-Ggr-039951	Gaeumannomyces graminis	70.44	0.00e+00	1061.00
IUUC-Gga-041183	Gallus gallus	96.75	0.00e+00	1418.00
IUUC-Gac-042039	Gasterosteus aculeatus	92.13	0.00e+00	1358.00
IUUC-Gma-044090	Glycine max	75.03	0.00e+00	1196.00
IUUC-Ggo-045568	Gorilla gorilla	95.88	0.00e+00	1412.00
IUUC-Hsa-046162	Homo sapiens	95.88	0.00e+00	1412.00
IUUC-Hvu-047107	Hordeum vulgare	78.02	0.00e+00	959.00
IUUC-Itr-047885	Ictidomys tridecemlineatus	95.64	0.00e+00	1409.00
IUUC-Kpa-049220	Komagataella pastoris	66.38	0.00e+00	1038.00
IUUC-Lch-050657	Latimeria chalumnae	86.77	0.00e+00	1216.00
IUUC-Lpe-051083	Leersia perrieri	78.27	0.00e+00	1169.00
IUUC-Loc-052064	Lepisosteus oculatus	94.63	0.00e+00	1367.00
IUUC-Lma-053323	Leptosphaeria maculans	71.17	0.00e+00	1071.00
IUUC-Laf-054574	Loxodonta africana	95.88	0.00e+00	1412.00
IUUC-Mcc-055448	Macaca mulatta	95.88	0.00e+00	1412.00
IUUC-Meu-056316	Macropus eugenii	89.39	0.00e+00	1281.00
IUUC-Mor-057057	Magnaporthe oryzae	70.27	0.00e+00	1058.00
IUUC-Mpo-057406	Magnaporthe poae	70.70	0.00e+00	1056.00
IUUC-Mtr-057648	Medicago truncatula	77.78	0.00e+00	1188.00
IUUC-Mla-059156	Melampsora laricipopulina	72.47	0.00e+00	1145.00
IUUC-Mga-060004	Meleagris gallopavo	90.17	0.00e+00	1176.00
IUUC-Mvi-060488	Microbotryum violaceum	73.12	0.00e+00	1130.00
IUUC-Mmr-061027	Microcebus murinus	95.88	0.00e+00	1412.00
IUUC-Mdo-062159	Monodelphis domestica	96.38	0.00e+00	1415.00
IUUC-Mmu-063633	Mus musculus	95.88	0.00e+00	1412.00
IUUC-Mac-064919	Musa acuminata	77.48	0.00e+00	1173.00
IUUC-Mpu-066078	Mustela putorius furo	95.76	0.00e+00	1415.00
IUUC-Mlu-067757	Myotis lucifugus	95.76	0.00e+00	1412.00
IUUC-Nfi-068533	Neosartorya fischeri	71.05	0.00e+00	1051.00
IUUC-Ncr-068775	Neurospora crassa	71.13	0.00e+00	1031.00
IUUC-Nle-069424	Nomascus leucogenys	95.88	0.00e+00	1412.00
IUUC-Opr-071147	Ochotona princeps	95.43	0.00e+00	1370.00
IUUC-Ont-071351	Oreochromis niloticus	92.63	0.00e+00	1337.00
IUUC-Oan-073335	Ornithorhynchus anatinus	94.89	0.00e+00	1417.00
IUUC-Ocu-074072	Oryctolagus cuniculus	95.88	0.00e+00	1412.00
IUUC-Oba-075914	Oryza barthii	78.14	0.00e+00	1190.00
IUUC-Obr-076224	Oryza brachyantha	78.58	0.00e+00	1184.00
IUUC-Ogl-077282	Oryza glaberrima	78.43	0.00e+00	1189.00
IUUC-Ogu-078174	Oryza glumaepatula	78.14	0.00e+00	1190.00
IUUC-Oin-079103	Oryza indica	78.14	0.00e+00	1190.00
IUUC-Olo-080675	Oryza longistaminata	78.27	0.00e+00	1191.00
IUUC-Ome-081247	Oryza meridionalis	78.14	0.00e+00	1190.00
IUUC-Oni-082078	Oryza nivara	78.01	0.00e+00	1189.00
IUUC-Opu-083806	Oryza punctata	78.17	0.00e+00	1195.00
IUUC-Oru-084634	Oryza rufipogon	78.14	0.00e+00	1191.00
IUUC-Osa-085960	Oryza sativa	78.14	0.00e+00	1190.00
IUUC-Ola-086382	Oryzias latipes	92.76	0.00e+00	1338.00
IUUC-Olu-087839	Ostreococcus lucimarinus	75.65	0.00e+00	1170.00
IUUC-Oga-088037	Otolemur garnettii	95.63	0.00e+00	1402.00
IUUC-Oar-089684	Ovis aries	93.80	0.00e+00	1409.00
IUUC-Ptr-091378	Pan troglodytes	95.88	0.00e+00	1412.00
IUUC-Pan-092849	Papio anubis	95.88	0.00e+00	1412.00
IUUC-Psi-093725	Pelodiscus sinensis	94.09	0.00e+00	1335.00
IUUC-Pma-094537	Petromyzon marinus	89.19	0.00e+00	689.00
IUUC-Pno-094915	Phaeosphaeria nodorum	73.81	0.00e+00	1013.00
IUUC-Ppa-095632	Physcomitrella patens	77.39	0.00e+00	1147.00
IUUC-Pfo-097440	Poecilia formosa	92.51	0.00e+00	1337.00
IUUC-Pab-098469	Pongo abelii	95.88	0.00e+00	1412.00
IUUC-Pop-100047	Populus trichocarpa	77.36	0.00e+00	1192.00
IUUC-Pca-100399	Procavia capensis	91.39	0.00e+00	1317.00
IUUC-Ppe-101767	Prunus persica	76.45	0.00e+00	1189.00
IUUC-Pva-102426	Pteropus vampyrus	95.13	0.00e+00	1371.00
IUUC-Pgr-103599	Puccinia graminis	71.69	0.00e+00	1128.00
IUUC-Ptt-103740	Puccinia triticina	71.82	0.00e+00	1129.00
IUUC-Pte-104030	Pyrenophora teres	70.62	0.00e+00	1054.00
IUUC-Pyt-104541	Pyrenophora triticirepentis	70.62	0.00e+00	1055.00
IUUC-Rno-105144	Rattus norvegicus	96.00	0.00e+00	1410.00
IUUC-Sce-106244	Saccharomyces cerevisiae	67.48	0.00e+00	981.00
IUUC-Sha-106589	Sarcophilus harrisii	96.25	0.00e+00	1413.00
IUUC-Sja-107673	Schizosaccharomyces japonicus	67.50	0.00e+00	1037.00
IUUC-Spo-108247	Schizosaccharomyces pombe	67.83	0.00e+00	1013.00
IUUC-Ssl-108642	Sclerotinia sclerotiorum	70.00	0.00e+00	1050.00
IUUC-Smo-108877	Selaginella moellendorffii	77.28	0.00e+00	1176.00
IUUC-Sit-110623	Setaria italica	78.04	0.00e+00	1186.00
IUUC-Sly-111151	Solanum lycopersicum	74.50	0.00e+00	1173.00
IUUC-Stu-111959	Solanum tuberosum	75.00	0.00e+00	1191.00
IUUC-Sar-113021	Sorex araneus	95.88	0.00e+00	1411.00
IUUC-Sbi-114457	Sorghum bicolor	78.72	0.00e+00	1192.00
IUUC-Sre-115052	Sporisorium reilianum	74.49	0.00e+00	1155.00
IUUC-Ssc-116293	Sus scrofa	95.52	0.00e+00	1410.00
IUUC-Tru-117991	Takifugu rubripes	95.10	0.00e+00	999.00
IUUC-Tsy-119131	Tarsius syrichta	92.33	0.00e+00	664.00
IUUC-Tni-120192	Tetraodon nigroviridis	90.89	0.00e+00	1325.00
IUUC-Tca-121502	Theobroma cacao	77.78	0.00e+00	1166.00
IUUC-Tre-122189	Trichoderma reesei	68.91	0.00e+00	1073.00
IUUC-Tvi-122310	Trichoderma virens	68.66	0.00e+00	1058.00
IUUC-Tae-124332	Triticum aestivum	77.85	0.00e+00	1179.00
IUUC-Tur-126733	Triticum urartu	77.59	0.00e+00	1163.00
IUUC-Tme-127147	Tuber melanosporum	70.71	0.00e+00	1047.00
IUUC-Tbe-127255	Tupaia belangeri	88.78	0.00e+00	1303.00
IUUC-Ttr-128876	Tursiops truncatus	95.24	0.00e+00	1395.00
IUUC-Uma-129448	Ustilago maydis	74.71	0.00e+00	1149.00
IUUC-Vda-129800	Verticillium dahliae	68.12	0.00e+00	1056.00
IUUC-Vpa-130573	Vicugna pacos	93.41	0.00e+00	766.00
IUUC-Vvi-131622	Vitis vinifera	78.20	0.00e+00	1193.00
IUUC-Xtr-132458	Xenopus tropicalis	94.65	0.00e+00	1328.00
IUUC-Xma-134045	Xiphophorus maculatus	92.63	0.00e+00	1337.00
IUUC-Yli-134382	Yarrowia lipolytica	69.54	0.00e+00	1066.00
IUUC-Zma-134817	Zea mays	78.46	0.00e+00	1194.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence