iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000056414.7	ENSDART00000078908.6	ENSDARP00000073367.5
ENSDARG00000056414.7	ENSDART00000151002.1	ENSDARP00000126161.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-79	268.1	379	769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 109  keknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke............ 185
           +ek+ + ++e+e+++ e +++  +++++++ ++++ +Fqgql  +++clec+  ++r+e+f+d+s+pv+++e+ +              
   Q: 379  QEKQDKDNSENENKTHEVKQDLGKNEEQSGLDVLKWMFQGQLVLRTRCLECECFTERREDFQDISVPVQEDETLSSDssseispdpkte 467
           3556666777777888888889999999999*****************************************876669*********** PP
   S: 186  ..slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfcts 267
             +l++++++f++ e++ g++ky+ce+c++++eae++l ++k Pev+++hLk+f     +++ +    +k+n+ +++pl+L+l ++ct+
   Q: 468  lkTLKWAISQFASVERIVGQDKYFCETCHHYTEAERSLLFDKTPEVITIHLKCFaangsEMDPY-AGLSKVNTPLQTPLKLSLHEWCTQ 555
           ******************************************************6655555554.4457******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvkn...................................................... 301
           p+     +  YeL+avv+HsG ++ssGHY++y++                                                       
   Q: 556  PD-----SPDYELFAVVMHSGvTISSGHYTTYIRMmdlhhtnikpqtqdeehdrdqeedmkqkkeetsqtdyddgevsfslsgrgrnva 639
           99.....678******************************************************************************* PP
   S: 302  ........................................................................................e 302
                                                                                                    
   Q: 640  rtsgtnnmssktagkrcsegvgllggqrsitsyelsnskqnnpdkpsslssrallqnavkkepeedcadavadgtqvsfdlalrnlldF 728
           *************************************************************9999999999999999999999988888 PP
   S: 303  kgkWllfdDskVtevkeeevleetg......staYvlfYkr 337
           +gkW+lfdDs+V+  +ee++l+ ++      st+Y+lfYkr
   Q: 729  EGKWMLFDDSEVRLYEEEDFLRACSpetcstSTPYLLFYKR 769
           999*******************999**************98 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MPGLHSDSGV VTAAGSPVKK SKLSLKFFQK KETKRALDFS EAPPEDNSNV TAEPQETICH 60
DQVVPLPCPS SPLTCEKRES LVPFVGFNNL GNTCYLNSIL QVLYYCPGFK EAIKSLCHVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGGCACTA GACGCAACTC CTTGTCGTGG AAAAAGCGCC AAGTTCTACA GCAAACGCGC 60
TTGTCAAGTT GTTTATATTT AACGCGAAAC CGCGTACTTT TAGAGTGTAC TCCGCAAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	49.51	0.00e+00	653.00
IUUC-Apl-004204	Anas platyrhynchos	49.67	5.00e-172	598.00
IUUC-Aca-004637	Anolis carolinensis	47.52	0.00e+00	629.00
IUUC-Ame-011718	Astyanax mexicanus	67.91	0.00e+00	916.00
IUUC-Bta-012552	Bos taurus	49.08	0.00e+00	650.00
IUUC-Cja-019588	Callithrix jacchus	49.39	0.00e+00	654.00
IUUC-Cfa-020211	Canis familiaris	49.21	0.00e+00	643.00
IUUC-Cpo-021551	Cavia porcellus	49.87	0.00e+00	636.00
IUUC-Csa-024186	Chlorocebus sabaeus	50.30	0.00e+00	653.00
IUUC-Cho-024739	Choloepus hoffmanni	42.77	2.00e-82	300.00
IUUC-Dno-029669	Dasypus novemcinctus	48.85	0.00e+00	640.00
IUUC-Dor-030168	Dipodomys ordii	46.72	1.00e-162	566.00
IUUC-Dme-031732	Drosophila melanogaster	29.11	5.00e-17	83.60
IUUC-Ete-032825	Echinops telfairi	46.37	3.00e-116	412.00
IUUC-Eca-033595	Equus caballus	48.46	2.00e-173	603.00
IUUC-Eeu-034877	Erinaceus europaeus	49.40	2.00e-72	267.00
IUUC-Fca-035381	Felis catus	52.13	6.00e-142	497.00
IUUC-Fal-037592	Ficedula albicollis	49.40	0.00e+00	628.00
IUUC-Gmo-039680	Gadus morhua	55.92	0.00e+00	706.00
IUUC-Gga-041196	Gallus gallus	47.75	0.00e+00	637.00
IUUC-Gac-042292	Gasterosteus aculeatus	54.39	0.00e+00	686.00
IUUC-Ggo-044671	Gorilla gorilla	49.45	0.00e+00	651.00
IUUC-Hsa-047020	Homo sapiens	49.51	0.00e+00	653.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	43.85	9.00e-158	550.00
IUUC-Lch-050543	Latimeria chalumnae	48.11	3.00e-167	582.00
IUUC-Loc-052338	Lepisosteus oculatus	57.87	0.00e+00	810.00
IUUC-Laf-053707	Loxodonta africana	48.44	0.00e+00	638.00
IUUC-Mcc-055885	Macaca mulatta	50.30	0.00e+00	660.00
IUUC-Meu-056573	Macropus eugenii	46.78	2.00e-157	549.00
IUUC-Mga-059346	Meleagris gallopavo	48.52	6.00e-176	611.00
IUUC-Mmr-061612	Microcebus murinus	48.28	0.00e+00	635.00
IUUC-Mdo-062887	Monodelphis domestica	50.18	0.00e+00	643.00
IUUC-Mmu-064044	Mus musculus	49.14	0.00e+00	636.00
IUUC-Mpu-066847	Mustela putorius furo	49.09	0.00e+00	647.00
IUUC-Mlu-067684	Myotis lucifugus	49.76	0.00e+00	640.00
IUUC-Nle-070057	Nomascus leucogenys	50.00	0.00e+00	653.00
IUUC-Opr-070463	Ochotona princeps	44.61	2.00e-156	546.00
IUUC-Ont-071975	Oreochromis niloticus	55.73	0.00e+00	690.00
IUUC-Ocu-074840	Oryctolagus cuniculus	49.08	0.00e+00	649.00
IUUC-Ola-087088	Oryzias latipes	53.38	0.00e+00	734.00
IUUC-Oga-088472	Otolemur garnettii	48.92	0.00e+00	642.00
IUUC-Oar-089498	Ovis aries	49.15	0.00e+00	652.00
IUUC-Ptr-091395	Pan troglodytes	49.39	0.00e+00	653.00
IUUC-Pan-092462	Papio anubis	50.18	0.00e+00	659.00
IUUC-Psi-093583	Pelodiscus sinensis	50.45	1.00e-158	553.00
IUUC-Pma-094644	Petromyzon marinus	41.06	4.00e-24	104.00
IUUC-Pfo-096314	Poecilia formosa	55.67	0.00e+00	748.00
IUUC-Pab-098568	Pongo abelii	49.82	0.00e+00	654.00
IUUC-Pca-100948	Procavia capensis	46.82	1.00e-80	294.00
IUUC-Pva-102853	Pteropus vampyrus	48.77	0.00e+00	637.00
IUUC-Rno-105573	Rattus norvegicus	48.71	0.00e+00	629.00
IUUC-Sha-107495	Sarcophilus harrisii	48.96	2.00e-147	516.00
IUUC-Sar-113545	Sorex araneus	42.63	4.00e-134	472.00
IUUC-Ssc-115962	Sus scrofa	49.51	0.00e+00	647.00
IUUC-Tgu-116731	Taeniopygia guttata	49.82	0.00e+00	629.00
IUUC-Tru-117893	Takifugu rubripes	54.17	0.00e+00	700.00
IUUC-Tsy-119644	Tarsius syrichta	46.67	2.00e-80	293.00
IUUC-Tni-119819	Tetraodon nigroviridis	53.12	0.00e+00	698.00
IUUC-Tbe-127272	Tupaia belangeri	47.03	2.00e-155	543.00
IUUC-Ttr-128404	Tursiops truncatus	49.39	0.00e+00	642.00
IUUC-Vpa-130205	Vicugna pacos	48.71	0.00e+00	635.00
IUUC-Xtr-132613	Xenopus tropicalis	46.63	3.00e-174	605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence