iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000010952.7	ENSRNOT00000086549.1	ENSRNOP00000071095.1
ENSRNOG00000010952.7	ENSRNOT00000014733.6	ENSRNOP00000014733.6

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-15	55.7	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D++i +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSIIIW 80
           8***********777*************** PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MRAVLTWRDK AEQCIYDLAF KPDGTQLILA AGNRLLVYDT SDGTLLQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSIIIW TSKLEGILKY THNDSIQCVS YNPVTHQLAS CSSSDFGLWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCCCTGCG CGCTCGGCGC TTCAGAGGAG GAGCTAGGCT CCCTTTTGGA CATGCGCACT 60
TGGAGCTTGC GAGCTCACGC GCGACCCATT GCGCATGTGC GTTGCTAAGG GTAGCAAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005929--C:cilium
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0060271--P:cilium assembly
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	94.93	0.00e+00	2356.00
IUUC-Apl-003504	Anas platyrhynchos	78.32	0.00e+00	1936.00
IUUC-Aca-004767	Anolis carolinensis	85.17	0.00e+00	2169.00
IUUC-Ame-011642	Astyanax mexicanus	75.44	0.00e+00	1912.00
IUUC-Bta-012969	Bos taurus	92.18	0.00e+00	2264.00
IUUC-Cel-018670	Caenorhabditis elegans	38.06	0.00e+00	898.00
IUUC-Cja-019249	Callithrix jacchus	86.56	0.00e+00	2118.00
IUUC-Cfa-020915	Canis familiaris	95.09	0.00e+00	2299.00
IUUC-Cpo-021888	Cavia porcellus	85.23	0.00e+00	2179.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	48.54	0.00e+00	1132.00
IUUC-Csa-023533	Chlorocebus sabaeus	91.30	0.00e+00	2260.00
IUUC-Cin-025121	Ciona intestinalis	57.66	0.00e+00	1512.00
IUUC-Csv-026240	Ciona savignyi	58.31	0.00e+00	1450.00
IUUC-Dno-029685	Dasypus novemcinctus	88.48	0.00e+00	2168.00
IUUC-Dme-032005	Drosophila melanogaster	26.61	7.00e-09	57.00
IUUC-Ete-032682	Echinops telfairi	84.06	0.00e+00	1669.00
IUUC-Eca-033831	Equus caballus	95.08	0.00e+00	2378.00
IUUC-Eeu-034919	Erinaceus europaeus	84.92	0.00e+00	1009.00
IUUC-Fca-036559	Felis catus	93.96	0.00e+00	2339.00
IUUC-Fal-037340	Ficedula albicollis	82.42	0.00e+00	2080.00
IUUC-Gga-040595	Gallus gallus	77.50	0.00e+00	1935.00
IUUC-Ggo-045356	Gorilla gorilla	87.83	0.00e+00	2231.00
IUUC-Hsa-046135	Homo sapiens	87.69	0.00e+00	2230.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	81.75	0.00e+00	1983.00
IUUC-Lch-050183	Latimeria chalumnae	81.44	0.00e+00	1162.00
IUUC-Loc-052049	Lepisosteus oculatus	80.59	0.00e+00	2054.00
IUUC-Laf-053728	Loxodonta africana	93.97	0.00e+00	2370.00
IUUC-Mcc-054971	Macaca mulatta	88.54	0.00e+00	2245.00
IUUC-Meu-056446	Macropus eugenii	85.06	0.00e+00	2175.00
IUUC-Mga-059296	Meleagris gallopavo	80.37	0.00e+00	2102.00
IUUC-Mmr-061232	Microcebus murinus	90.42	0.00e+00	2271.00
IUUC-Mdo-062115	Monodelphis domestica	92.67	0.00e+00	2320.00
IUUC-Mmu-063664	Mus musculus	98.31	0.00e+00	2487.00
IUUC-Mpu-066136	Mustela putorius furo	91.00	0.00e+00	2275.00
IUUC-Mlu-068238	Myotis lucifugus	90.08	0.00e+00	2261.00
IUUC-Nle-069003	Nomascus leucogenys	87.69	0.00e+00	2147.00
IUUC-Ont-072080	Oreochromis niloticus	75.42	0.00e+00	1953.00
IUUC-Oan-072891	Ornithorhynchus anatinus	82.10	0.00e+00	926.00
IUUC-Ocu-074262	Oryctolagus cuniculus	91.22	0.00e+00	2269.00
IUUC-Ola-086538	Oryzias latipes	73.04	0.00e+00	1863.00
IUUC-Oga-088722	Otolemur garnettii	89.47	0.00e+00	2232.00
IUUC-Oar-089249	Ovis aries	88.40	0.00e+00	2185.00
IUUC-Ptr-090752	Pan troglodytes	90.87	0.00e+00	2067.00
IUUC-Pan-092472	Papio anubis	91.47	0.00e+00	2258.00
IUUC-Psi-093335	Pelodiscus sinensis	85.67	0.00e+00	2170.00
IUUC-Pma-094520	Petromyzon marinus	67.30	0.00e+00	1620.00
IUUC-Ppa-095600	Physcomitrella patens	62.83	5.00e-40	156.00
IUUC-Pfo-096526	Poecilia formosa	72.41	0.00e+00	1816.00
IUUC-Pab-098428	Pongo abelii	88.64	0.00e+00	1096.00
IUUC-Pca-100233	Procavia capensis	71.37	0.00e+00	989.00
IUUC-Pva-103064	Pteropus vampyrus	81.26	0.00e+00	1984.00
IUUC-Sha-106649	Sarcophilus harrisii	92.35	0.00e+00	2307.00
IUUC-Smo-109287	Selaginella moellendorffii	37.65	0.00e+00	806.00
IUUC-Tgu-116870	Taeniopygia guttata	83.18	0.00e+00	2051.00
IUUC-Tru-118661	Takifugu rubripes	70.87	0.00e+00	1816.00
IUUC-Tsy-119640	Tarsius syrichta	75.75	0.00e+00	657.00
IUUC-Tni-120812	Tetraodon nigroviridis	72.08	0.00e+00	1822.00
IUUC-Ttr-128862	Tursiops truncatus	90.10	0.00e+00	2311.00
IUUC-Vpa-130049	Vicugna pacos	84.98	3.00e-157	549.00
IUUC-Xtr-131914	Xenopus tropicalis	78.18	0.00e+00	1976.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence