iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019730

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01009000

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000004855.1	ENSCJAT00000009397.1	ENSCJAP00000008892.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-07	33.2	12	53
UBD/SH3	9.10e-48	161.0	450	505

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VGSRNELRCPECR 53
           **********9**************9777....899*********8 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +  ++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 450  VYVAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPV 505
           5679**********************9.555.569********************988 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VGSRNELRCP ECRTLVGSGV 60
EELPSNILLV RLLDGIKQRP WKPGPGGGSG TSCTNALRSQ SSTVANCNSK DLQSSQGGQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGTGACTCT AGAGCAAAGT CTGAAATGGA TGTAACATGA ATCATTTTAA GGGATGCACA 60
CGACTATGAA CATTTCTGAA GCCTTTTTCT CAGTAAAGTA GATAAAGATG GATGAATCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

KEGG

cjc:100406174

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	89.14	0.00e+00	1293.00
IUUC-Apl-003961	Anas platyrhynchos	79.55	0.00e+00	1152.00
IUUC-Aca-004386	Anolis carolinensis	76.04	0.00e+00	1145.00
IUUC-Ame-010659	Astyanax mexicanus	72.73	8.00e-149	521.00
IUUC-Bta-012563	Bos taurus	89.32	2.00e-104	373.00
IUUC-Cfa-020992	Canis familiaris	88.88	0.00e+00	1322.00
IUUC-Cpo-021304	Cavia porcellus	92.70	0.00e+00	1404.00
IUUC-Csa-023925	Chlorocebus sabaeus	96.40	0.00e+00	1363.00
IUUC-Cho-024630	Choloepus hoffmanni	83.21	0.00e+00	871.00
IUUC-Cin-025274	Ciona intestinalis	49.06	7.00e-70	257.00
IUUC-Csv-026136	Ciona savignyi	41.69	1.00e-70	259.00
IUUC-Dre-028290	Danio rerio	66.46	0.00e+00	733.00
IUUC-Dno-029083	Dasypus novemcinctus	87.21	0.00e+00	1241.00
IUUC-Dor-030388	Dipodomys ordii	87.15	0.00e+00	778.00
IUUC-Dme-032207	Drosophila melanogaster	42.25	2.00e-63	237.00
IUUC-Ete-032809	Echinops telfairi	78.48	0.00e+00	814.00
IUUC-Eca-034185	Equus caballus	90.67	0.00e+00	1082.00
IUUC-Eeu-034816	Erinaceus europaeus	77.07	0.00e+00	1099.00
IUUC-Fca-036439	Felis catus	89.25	0.00e+00	1345.00
IUUC-Fal-037074	Ficedula albicollis	78.99	0.00e+00	1138.00
IUUC-Gmo-039443	Gadus morhua	69.11	1.00e-92	334.00
IUUC-Gga-040749	Gallus gallus	77.91	0.00e+00	1111.00
IUUC-Gac-041420	Gasterosteus aculeatus	73.84	4.00e-145	508.00
IUUC-Ggo-045215	Gorilla gorilla	96.40	0.00e+00	1384.00
IUUC-Hsa-046315	Homo sapiens	95.96	0.00e+00	1377.00
IUUC-Itr-048265	Ictidomys tridecemlineatus	89.55	3.00e-150	524.00
IUUC-Lch-049453	Latimeria chalumnae	69.28	0.00e+00	867.00
IUUC-Loc-052248	Lepisosteus oculatus	39.19	5.00e-75	275.00
IUUC-Laf-053651	Loxodonta africana	89.13	0.00e+00	1295.00
IUUC-Mcc-054688	Macaca mulatta	94.73	0.00e+00	1383.00
IUUC-Meu-056291	Macropus eugenii	74.17	0.00e+00	768.00
IUUC-Mga-059944	Meleagris gallopavo	77.64	0.00e+00	1121.00
IUUC-Mmr-061553	Microcebus murinus	90.67	0.00e+00	1231.00
IUUC-Mdo-062313	Monodelphis domestica	76.56	0.00e+00	1134.00
IUUC-Mmu-063516	Mus musculus	89.05	0.00e+00	1352.00
IUUC-Mpu-066064	Mustela putorius furo	89.10	0.00e+00	1305.00
IUUC-Mlu-067312	Myotis lucifugus	87.19	0.00e+00	1268.00
IUUC-Nle-069035	Nomascus leucogenys	96.18	0.00e+00	1384.00
IUUC-Opr-070690	Ochotona princeps	85.26	0.00e+00	644.00
IUUC-Ont-071484	Oreochromis niloticus	66.13	0.00e+00	706.00
IUUC-Oan-073305	Ornithorhynchus anatinus	81.93	0.00e+00	1212.00
IUUC-Ocu-074936	Oryctolagus cuniculus	90.19	0.00e+00	1345.00
IUUC-Ola-086675	Oryzias latipes	59.03	2.00e-172	599.00
IUUC-Oga-087933	Otolemur garnettii	81.15	0.00e+00	999.00
IUUC-Oar-090408	Ovis aries	88.98	2.00e-105	376.00
IUUC-Ptr-090865	Pan troglodytes	96.29	0.00e+00	1383.00
IUUC-Pan-092362	Papio anubis	96.63	0.00e+00	1363.00
IUUC-Psi-093876	Pelodiscus sinensis	78.34	0.00e+00	1160.00
IUUC-Pfo-097116	Poecilia formosa	66.72	0.00e+00	706.00
IUUC-Pab-098127	Pongo abelii	96.07	0.00e+00	1382.00
IUUC-Pca-100485	Procavia capensis	87.97	0.00e+00	976.00
IUUC-Pva-102661	Pteropus vampyrus	88.43	0.00e+00	1242.00
IUUC-Rno-105728	Rattus norvegicus	87.42	0.00e+00	1332.00
IUUC-Sha-106515	Sarcophilus harrisii	85.21	0.00e+00	842.00
IUUC-Sar-113161	Sorex araneus	95.22	0.00e+00	644.00
IUUC-Ssc-115314	Sus scrofa	76.85	0.00e+00	1063.00
IUUC-Tgu-117012	Taeniopygia guttata	79.33	0.00e+00	1132.00
IUUC-Tru-118467	Takifugu rubripes	61.65	6.00e-157	548.00
IUUC-Tsy-119566	Tarsius syrichta	84.03	5.00e-175	608.00
IUUC-Tni-120830	Tetraodon nigroviridis	58.07	9.00e-162	563.00
IUUC-Tbe-128070	Tupaia belangeri	97.96	0.00e+00	702.00
IUUC-Ttr-128161	Tursiops truncatus	93.73	1.00e-135	477.00
IUUC-Xtr-132628	Xenopus tropicalis	72.40	0.00e+00	1038.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence