iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037345

Ensembl Protein ID

ENSFALP00000012394.1

UniProt Accession

U3KBJ0; U3KBJ0_FICAL

Genbank Protein ID

ENSFALP00000012394

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000576

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000011866.1	ENSFALT00000012444.1	ENSFALP00000012394.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-42	140.9	193	234
UBD/Beta-Prp	3.50e-55	187.0	147	352

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllks 38
           gH ++v cl++    +++++vsG+ D++ +vWD+rtg +++s
   Q: 193  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRTGQCVQS 234
           8***********9644499********************996 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd++tgqc++  
   Q: 147  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRTGQCVQ-S 234
           567889999*********99***************************************9777************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ hd+ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 235  FETHDSDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 323
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++riW
   Q: 324  HENRVSTLRVSPDGTAFCSGSWDHTLRIW 352
           ***************************** PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MATEGLHENE TLASLKSEAE SLKGKLEEER AKLHDVELHQ VAERVEALGQ FVMKTRRTLK 60
GHGNKVLCMD WCKDKRRIVS SSQDGKVIVW DSFTTNKEHA VTMPCTWVMA CAYAPSGCAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG 60
GGGGGAGCAG GAGCAGGGAT GCTGGGGCAG CAGAACAGGG GACACAGGAG CAGCAGGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

KEGG

fab:101807033

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	90.65	0.00e+00	674.00
IUUC-Apl-003399	Anas platyrhynchos	98.72	0.00e+00	651.00
IUUC-Aca-004861	Anolis carolinensis	98.30	0.00e+00	726.00
IUUC-Ame-011851	Astyanax mexicanus	91.17	0.00e+00	684.00
IUUC-Bta-012438	Bos taurus	97.73	0.00e+00	724.00
IUUC-Cel-018408	Caenorhabditis elegans	65.22	8.00e-140	489.00
IUUC-Cja-019086	Callithrix jacchus	98.58	0.00e+00	724.00
IUUC-Cfa-021255	Canis familiaris	97.97	0.00e+00	671.00
IUUC-Cpo-021398	Cavia porcellus	96.05	0.00e+00	712.00
IUUC-Csa-023776	Chlorocebus sabaeus	98.30	0.00e+00	728.00
IUUC-Cin-025305	Ciona intestinalis	58.74	9.00e-133	466.00
IUUC-Csv-026058	Ciona savignyi	57.87	4.00e-129	454.00
IUUC-Dre-028572	Danio rerio	92.00	0.00e+00	684.00
IUUC-Dno-029958	Dasypus novemcinctus	83.47	1.00e-119	422.00
IUUC-Dor-031013	Dipodomys ordii	97.27	8.00e-152	529.00
IUUC-Dme-031889	Drosophila melanogaster	68.02	2.00e-148	517.00
IUUC-Eca-033977	Equus caballus	93.16	0.00e+00	683.00
IUUC-Eeu-035079	Erinaceus europaeus	97.45	0.00e+00	724.00
IUUC-Fca-035693	Felis catus	90.93	0.00e+00	671.00
IUUC-Gmo-039222	Gadus morhua	90.93	0.00e+00	660.00
IUUC-Gga-040320	Gallus gallus	98.87	0.00e+00	731.00
IUUC-Gac-042644	Gasterosteus aculeatus	90.65	0.00e+00	686.00
IUUC-Ggo-044489	Gorilla gorilla	94.35	0.00e+00	686.00
IUUC-Hsa-046434	Homo sapiens	98.58	0.00e+00	729.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	92.09	2.00e-175	607.00
IUUC-Loc-052790	Lepisosteus oculatus	94.86	0.00e+00	673.00
IUUC-Laf-054255	Loxodonta africana	96.87	0.00e+00	713.00
IUUC-Mcc-055610	Macaca mulatta	98.29	0.00e+00	723.00
IUUC-Meu-056819	Macropus eugenii	96.15	2.00e-180	624.00
IUUC-Mga-059740	Meleagris gallopavo	91.53	0.00e+00	667.00
IUUC-Mmr-061221	Microcebus murinus	97.73	0.00e+00	724.00
IUUC-Mdo-062619	Monodelphis domestica	97.45	0.00e+00	723.00
IUUC-Mmu-064266	Mus musculus	98.02	0.00e+00	728.00
IUUC-Mpu-065766	Mustela putorius furo	97.67	3.00e-180	623.00
IUUC-Mlu-067221	Myotis lucifugus	89.80	0.00e+00	663.00
IUUC-Nle-069515	Nomascus leucogenys	98.10	0.00e+00	656.00
IUUC-Opr-070195	Ochotona princeps	89.24	0.00e+00	641.00
IUUC-Ont-071535	Oreochromis niloticus	81.87	4.00e-158	550.00
IUUC-Oan-072899	Ornithorhynchus anatinus	96.76	8.00e-107	378.00
IUUC-Ocu-074666	Oryctolagus cuniculus	98.01	1.00e-180	624.00
IUUC-Ola-086578	Oryzias latipes	91.76	0.00e+00	650.00
IUUC-Oga-089090	Otolemur garnettii	97.46	0.00e+00	721.00
IUUC-Oar-090017	Ovis aries	92.29	0.00e+00	662.00
IUUC-Ptr-091280	Pan troglodytes	98.11	0.00e+00	657.00
IUUC-Pan-092198	Papio anubis	97.48	0.00e+00	655.00
IUUC-Psi-093030	Pelodiscus sinensis	89.80	0.00e+00	667.00
IUUC-Pma-094140	Petromyzon marinus	88.89	3.00e-89	320.00
IUUC-Pfo-097182	Poecilia formosa	92.07	0.00e+00	665.00
IUUC-Pab-098157	Pongo abelii	98.58	0.00e+00	731.00
IUUC-Pca-100988	Procavia capensis	73.94	8.00e-144	503.00
IUUC-Pva-102232	Pteropus vampyrus	85.43	1.00e-175	608.00
IUUC-Rno-105526	Rattus norvegicus	94.37	0.00e+00	689.00
IUUC-Sce-106298	Saccharomyces cerevisiae	36.15	1.00e-68	253.00
IUUC-Sha-106754	Sarcophilus harrisii	98.02	0.00e+00	680.00
IUUC-Ssc-115390	Sus scrofa	97.74	0.00e+00	723.00
IUUC-Tgu-117377	Taeniopygia guttata	98.73	0.00e+00	656.00
IUUC-Tru-117938	Takifugu rubripes	92.07	0.00e+00	653.00
IUUC-Tsy-119392	Tarsius syrichta	81.87	6.00e-166	576.00
IUUC-Tni-119834	Tetraodon nigroviridis	76.20	9.00e-153	532.00
IUUC-Tbe-127469	Tupaia belangeri	95.73	0.00e+00	687.00
IUUC-Ttr-128252	Tursiops truncatus	97.45	0.00e+00	716.00
IUUC-Vpa-130173	Vicugna pacos	89.84	1.00e-136	478.00
IUUC-Xtr-131803	Xenopus tropicalis	97.17	0.00e+00	680.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence