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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064013
Ensembl Protein ID ENSMUSP00000065787.7
UniProt Accession A2AC93; A2AC94; DNAI2_MOUSE
Genbank Protein ID ABU62629.1; CAM19252.1; CAM19253.1; EDL34441.1
Protein Name Dynein intermediate chain 2, axonemal; Axonemal dynein intermediate chain 2
Genbank Nucleotide ID EF565270; AL663079; AL663079; CH466558
Gene Name Dnaic2; Dnai2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000034706.16 ENSMUST00000069325.13 ENSMUSP00000065787.7
ENSMUSG00000034706.16 ENSMUST00000141762.2 ENSMUSP00000114700.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IIDHINT
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.50e-07 31.9 262 296
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf....sdtllvsGsdDgtikvWDlrt 32
           H d+v++  +    ++t   s+s Dg+++ WD+r+
   Q: 262  HRDPVYGTIWlqskTGTECFSASTDGQVMWWDIRK 296
           9******99**9854499***********99*875 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Part of the dynein complex of respiratory cilia.
 Part of the dynein complex of respiratory cilia.
Protein Sequence
(Fasta)
MEIVYVYLKK RSEFGKQCNF SDRQAELNID ILPNPELAAL YVERNPVDTG IQCSASMSEH 60
EANTERFEME SCGVNHVEGG WPKDVNPQEL EQTIRFRKKV EKDENYINAV MQLGSIMEHC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064013|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGCAGCTCC CAGCCGTTTA AGCTGCGCTG GAGCTGGGAC TGGTCTTGGG CGCTTCTCCT 60
GGGCTGTGTG GCAGGAGGTG AGCCAGGATA AGGGGCGGGC GTCCTAGAGG ACGTCCAAGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064013|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0966--Cell projection
KW-0969--Cilium
KW-0970--Cilium biogenesis/degradation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0243--Dynein
KW-0493--Microtubule
KW-0505--Motor protein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0005858--C:axonemal dynein complex
GO:0005930--C:axoneme
GO:0005737--C:cytoplasm
GO:0009897--C:external side of plasma membrane
GO:0005874--C:microtubule
GO:0036157--C:outer dynein arm
GO:0036126--C:sperm flagellum
GO:0003777--F:microtubule motor activity
GO:0060271--P:cilium assembly
GO:0003341--P:cilium movement
GO:0007368--P:determination of left/right symmetry
GO:0036158--P:outer dynein arm assembly
KEGG mmu:432611
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002114 Ailuropoda melanoleuca 90.00 0.00e+00 1027.00
IUUC-Apl-003601 Anas platyrhynchos 59.65 2.00e-178 619.00
IUUC-Aca-004317 Anolis carolinensis 76.24 0.00e+00 863.00
IUUC-Ame-011079 Astyanax mexicanus 73.97 0.00e+00 854.00
IUUC-Bta-013371 Bos taurus 88.91 0.00e+00 1049.00
IUUC-Cja-019197 Callithrix jacchus 87.85 0.00e+00 1028.00
IUUC-Cfa-020952 Canis familiaris 90.32 0.00e+00 1024.00
IUUC-Cpo-021626 Cavia porcellus 88.91 0.00e+00 1033.00
IUUC-Csa-024182 Chlorocebus sabaeus 88.72 0.00e+00 820.00
IUUC-Cin-025729 Ciona intestinalis 70.04 0.00e+00 813.00
IUUC-Dre-027792 Danio rerio 70.86 0.00e+00 837.00
IUUC-Dor-030901 Dipodomys ordii 90.38 0.00e+00 694.00
IUUC-Dme-032221 Drosophila melanogaster 47.34 2.00e-151 528.00
IUUC-Ete-032722 Echinops telfairi 72.01 9.00e-106 377.00
IUUC-Eca-033738 Equus caballus 89.96 0.00e+00 1034.00
IUUC-Eeu-035352 Erinaceus europaeus 91.16 0.00e+00 939.00
IUUC-Fca-035837 Felis catus 88.39 0.00e+00 1031.00
IUUC-Fal-037517 Ficedula albicollis 59.88 5.00e-176 610.00
IUUC-Gmo-039097 Gadus morhua 67.56 0.00e+00 797.00
IUUC-Gga-040662 Gallus gallus 71.86 0.00e+00 806.00
IUUC-Ggo-044511 Gorilla gorilla 79.61 0.00e+00 886.00
IUUC-Hsa-046087 Homo sapiens 88.20 0.00e+00 1030.00
IUUC-Lch-050054 Latimeria chalumnae 60.27 0.00e+00 633.00
IUUC-Loc-052653 Lepisosteus oculatus 74.73 0.00e+00 858.00
IUUC-Laf-054419 Loxodonta africana 90.14 0.00e+00 1006.00
IUUC-Mcc-055327 Macaca mulatta 88.91 0.00e+00 1025.00
IUUC-Meu-056884 Macropus eugenii 77.88 0.00e+00 919.00
IUUC-Mga-059416 Meleagris gallopavo 69.68 0.00e+00 795.00
IUUC-Mmr-060606 Microcebus murinus 88.89 0.00e+00 841.00
IUUC-Mdo-062393 Monodelphis domestica 81.42 0.00e+00 917.00
IUUC-Mpu-066113 Mustela putorius furo 89.25 0.00e+00 1026.00
IUUC-Mlu-067127 Myotis lucifugus 88.91 0.00e+00 1006.00
IUUC-Nle-070070 Nomascus leucogenys 88.03 0.00e+00 1023.00
IUUC-Ont-071507 Oreochromis niloticus 67.26 0.00e+00 785.00
IUUC-Ocu-074567 Oryctolagus cuniculus 89.79 0.00e+00 1068.00
IUUC-Oar-089689 Ovis aries 88.93 0.00e+00 1036.00
IUUC-Ptr-090655 Pan troglodytes 88.56 0.00e+00 1032.00
IUUC-Pan-091972 Papio anubis 90.71 0.00e+00 692.00
IUUC-Psi-093058 Pelodiscus sinensis 75.47 0.00e+00 835.00
IUUC-Pma-094529 Petromyzon marinus 65.24 9.00e-127 446.00
IUUC-Pfo-096487 Poecilia formosa 64.66 0.00e+00 677.00
IUUC-Pca-100964 Procavia capensis 88.63 0.00e+00 904.00
IUUC-Pva-102976 Pteropus vampyrus 84.05 0.00e+00 957.00
IUUC-Rno-105223 Rattus norvegicus 95.43 0.00e+00 1000.00
IUUC-Sha-107223 Sarcophilus harrisii 75.27 0.00e+00 845.00
IUUC-Ssc-116431 Sus scrofa 89.79 0.00e+00 1058.00
IUUC-Tru-117709 Takifugu rubripes 63.27 0.00e+00 759.00
IUUC-Tni-120615 Tetraodon nigroviridis 61.04 0.00e+00 711.00
IUUC-Ttr-128858 Tursiops truncatus 77.98 2.00e-149 522.00
IUUC-Xtr-132350 Xenopus tropicalis 72.71 0.00e+00 883.00
Created Date 25-Jun-2017

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