iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004292

UUCD1 version

UUC-AnC-00032

Ensembl Protein ID

ENSACAP00000012135.3

UniProt Accession

H9GIT8; H9GIT8_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000012365.3	ENSACAT00000012380.3	ENSACAP00000012135.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.20e-14	53.5	58	124
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.50e-06	25.7	126	154

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+lv g+++f++h ++L+a S +F+a+f+ + ee+  ++ v+++ + +++++ +l+++Y g ++++
   Q: 58   TDVVLVMGKQRFPCHQATLSANSAYFRAMFSVKAEEGC-QSIVNLQAMPATSMSLVLDYMYGGDVSIQ 124
           7************************************8.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
           +N+ g+l +++l++ p+Lkda+++f++++
   Q: 126  DNVEGLLELSNLLQIPRLKDACITFLERQ 154
           7999*********************9886 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MMYQVMKQET NYGTNGSDNT KLLDQRSKRL PMKLFRGPCH AEHILQTLNS YRQDGIFTDV 60
VLVMGKQRFP CHQATLSANS AYFRAMFSVK AEEGCQSIVN LQAMPATSMS LVLDYMYGGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCATCTTCA AATTCTCCCT TTTAGAGGCA GAAGGGGGGA GAGGAGAGAC CCTCCTCCTG 60
CGGAGACTAT TCATTGACAG CTGCAGCAAA TGCCACGCCA ATCCTTTGGG CAGCAAGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030601--KLHL35
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003919	Anas platyrhynchos	72.92	0.00e+00	882.00
IUUC-Bta-012754	Bos taurus	54.37	4.00e-167	581.00
IUUC-Cja-019390	Callithrix jacchus	53.65	6.00e-160	557.00
IUUC-Cfa-021181	Canis familiaris	54.92	3.00e-168	584.00
IUUC-Dno-028982	Dasypus novemcinctus	54.77	3.00e-171	594.00
IUUC-Gga-041027	Gallus gallus	70.70	0.00e+00	891.00
IUUC-Ggo-045055	Gorilla gorilla	54.08	2.00e-165	575.00
IUUC-Hsa-046044	Homo sapiens	58.56	9.00e-149	520.00
IUUC-Itr-048569	Ictidomys tridecemlineatus	55.12	0.00e+00	633.00
IUUC-Lch-050580	Latimeria chalumnae	56.46	0.00e+00	718.00
IUUC-Loc-052921	Lepisosteus oculatus	53.55	3.00e-173	601.00
IUUC-Laf-053674	Loxodonta africana	52.56	6.00e-160	557.00
IUUC-Mga-059938	Meleagris gallopavo	71.50	0.00e+00	867.00
IUUC-Mdo-062790	Monodelphis domestica	56.41	6.00e-176	610.00
IUUC-Mmu-064185	Mus musculus	56.50	4.00e-174	604.00
IUUC-Mpu-065712	Mustela putorius furo	54.51	0.00e+00	627.00
IUUC-Ocu-074956	Oryctolagus cuniculus	54.40	0.00e+00	636.00
IUUC-Ptr-091651	Pan troglodytes	58.78	5.00e-150	524.00
IUUC-Psi-093093	Pelodiscus sinensis	71.45	0.00e+00	885.00
IUUC-Rno-105037	Rattus norvegicus	55.96	5.00e-172	597.00
IUUC-Sha-106719	Sarcophilus harrisii	55.99	7.00e-176	610.00
IUUC-Ssc-116393	Sus scrofa	54.92	3.00e-174	604.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence