iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053999

UUCD1 version

UUC-LoA-01100

Ensembl Protein ID

ENSLAFP00000012562.3

UniProt Accession

G3TEA6; G3TEA6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000015007.3	ENSLAFT00000015007.3	ENSLAFP00000012562.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-83	280.4	437	842

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs   qq
   Q: 437  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 514
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+  + +++ k+++  + +e++++ +++ ++++F+g++ ++i+cl+c +vssree f+dlsl++p +
   Q: 515  DCSEYLKYLLDRLHEEE-----KTGARICQKLKQSTLPSPPEEPPSPSSTSVEKMFGGKIVTRIRCLRCLHVSSREEAFTDLSLAFPPE 598
           *****************.....567777777777777788999********************************************** PP
   S: 180  eetkke.......................................................................slqdcLesftke 197
           e ++                                                                         s+ d+ + f ++
   Q: 599  EVRARDlppqprfqipsqegprrqrkhcitgdapstildiaslgspgpvgqrcsqglsthrdaapsgeqvcgpegsrSVLDLVNYFLSP 687
           *998779********************************************************************************** PP
   S: 198  eelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvH 286
           e+l+ en+yyc++c ++q+aek ++l++ P++Lil L Rfsf+ ++++r+ki + v++pl L l     +        + Y+L++vvvH
   Q: 688  ERLTAENRYYCDSCASLQDAEKAVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGGQ-------GQAYDLCSVVVH 769
           ***********************************************************99999844444.......89********** PP
   S: 287  sG.slssGHYvayvkn................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
           sG s++sGHY++y+++                 +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 770  SGvSSESGHYYCYAREgaarpppslgtadrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 842
           ****************99999999999999888999*******************999************985 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MDKILEAVVT SSYPASVKQG LVRRVLEAAR QPLEREQCLA LLTLGARLYV GGTEELPRRV 60
GCQLLHVAGR HHPEVFAEFF NARRVLRLLQ SLACVQLGLQ LLPEGPAADE VFALLRREVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGC GGTGGTGACA TCGTCGTACC CAGCAAGTGT GAAGCAAGGA 60
TTGGTGCGGC GCGTGCTAGA GGCAGCGCGG CAGCCGCTGG AGCGAGAGCA GTGCCTGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	80.60	0.00e+00	985.00
IUUC-Apl-004121	Anas platyrhynchos	63.44	0.00e+00	1117.00
IUUC-Aca-005070	Anolis carolinensis	62.32	0.00e+00	796.00
IUUC-Bta-012545	Bos taurus	89.74	0.00e+00	1130.00
IUUC-Cja-019731	Callithrix jacchus	89.02	0.00e+00	1133.00
IUUC-Cfa-020095	Canis familiaris	90.21	0.00e+00	1172.00
IUUC-Cpo-021961	Cavia porcellus	87.78	0.00e+00	1300.00
IUUC-Csa-023167	Chlorocebus sabaeus	85.30	0.00e+00	1410.00
IUUC-Dno-029186	Dasypus novemcinctus	81.91	0.00e+00	811.00
IUUC-Dor-030538	Dipodomys ordii	94.39	0.00e+00	983.00
IUUC-Ete-032512	Echinops telfairi	90.91	3.00e-106	379.00
IUUC-Eca-033279	Equus caballus	95.35	0.00e+00	895.00
IUUC-Eeu-035120	Erinaceus europaeus	69.15	0.00e+00	808.00
IUUC-Fca-035969	Felis catus	89.70	0.00e+00	879.00
IUUC-Fal-037625	Ficedula albicollis	64.20	0.00e+00	1140.00
IUUC-Gga-040767	Gallus gallus	63.47	0.00e+00	1155.00
IUUC-Ggo-045323	Gorilla gorilla	88.76	0.00e+00	885.00
IUUC-Hsa-046124	Homo sapiens	89.52	0.00e+00	1127.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	89.88	0.00e+00	1567.00
IUUC-Lch-049513	Latimeria chalumnae	57.14	0.00e+00	980.00
IUUC-Loc-052698	Lepisosteus oculatus	51.56	0.00e+00	898.00
IUUC-Mcc-055266	Macaca mulatta	87.57	0.00e+00	1100.00
IUUC-Meu-056906	Macropus eugenii	73.11	0.00e+00	971.00
IUUC-Mga-059595	Meleagris gallopavo	64.26	0.00e+00	1139.00
IUUC-Mdo-062167	Monodelphis domestica	71.95	0.00e+00	1301.00
IUUC-Mmu-063298	Mus musculus	87.74	0.00e+00	1136.00
IUUC-Mpu-066195	Mustela putorius furo	88.86	0.00e+00	1146.00
IUUC-Mlu-067583	Myotis lucifugus	82.29	0.00e+00	1050.00
IUUC-Opr-070454	Ochotona princeps	86.86	1.00e-155	543.00
IUUC-Ocu-074121	Oryctolagus cuniculus	81.61	0.00e+00	1290.00
IUUC-Oga-088593	Otolemur garnettii	89.09	0.00e+00	1508.00
IUUC-Oar-090140	Ovis aries	89.29	0.00e+00	1115.00
IUUC-Pan-092168	Papio anubis	85.40	0.00e+00	1412.00
IUUC-Psi-093707	Pelodiscus sinensis	65.26	0.00e+00	1182.00
IUUC-Pab-097614	Pongo abelii	88.43	0.00e+00	1117.00
IUUC-Pca-100683	Procavia capensis	87.69	0.00e+00	1134.00
IUUC-Pva-103146	Pteropus vampyrus	76.55	0.00e+00	991.00
IUUC-Rno-105061	Rattus norvegicus	87.98	0.00e+00	1139.00
IUUC-Sha-106686	Sarcophilus harrisii	70.86	0.00e+00	952.00
IUUC-Tgu-117024	Taeniopygia guttata	66.28	0.00e+00	1164.00
IUUC-Tsy-119505	Tarsius syrichta	75.31	4.00e-159	555.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence