iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069254

Ensembl Protein ID

ENSNLEP00000009652.1

UniProt Accession

G1R8W5; G1R8W5_NOMLE

Genbank Protein ID

ENSNLEP00000009652

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01066615

Gene Name

MUL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000007916.2	ENSNLET00000010114.2	ENSNLEP00000009652.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.09	0.00e+00	667.00	IUUC-Hsa-046597

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MESGGRPSLC QFILLGTTSV VTAVLYSVYR QKAQVSQELK GAKKVHLGED LKTILSEAPG 60
KCVPYAVIEG MFAYWLMENN ITAQEFETSL VNMTLQEHKM VWNRTTHLWN DCSKIIHQRT 120

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Nucleotide Sequence
(Fasta)

ATGGAGAGCG GAGGGCGGCC CTCGCTGTGT CAGTTCATCC TTCTGGGCAC CACCTCTGTG 60
GTCACCGCCG TCCTGTATTC CGTGTACCGG CAGAAGGCCC AGGTCTCTCA AGAGCTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR022170--GIDE
IPR001841--Znf_RING

PROSITE

PS50089--ZF_RING_2

Pfam

PF12483--GIDE

Gene Ontology

GO:0030424--C:axon
GO:0031307--C:integral component of mitochondrial outer membrane
GO:0043025--C:neuronal cell body
GO:0005777--C:peroxisome
GO:0004871--F:signal transducer activity
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257--P:activation of JUN kinase activity
GO:0071360--P:cellular response to exogenous dsRNA
GO:0000266--P:mitochondrial fission
GO:0051646--P:mitochondrion localization
GO:0030308--P:negative regulation of cell growth
GO:0071650--P:negative regulation of chemokine (C-C motif) ligand 5 production
GO:0050689--P:negative regulation of defense response to virus by host
GO:0010637--P:negative regulation of mitochondrial fusion
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0060339--P:negative regulation of type I interferon-mediated signaling pathway
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0090141--P:positive regulation of mitochondrial fission
GO:0033235--P:positive regulation of protein sumoylation
GO:0031648--P:protein destabilization
GO:0050821--P:protein stabilization
GO:1901028--P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000342	Aegilops tauschii	23.32	2.00e-09	58.20
IUUC-Aml-002287	Ailuropoda melanoleuca	86.44	4.00e-173	600.00
IUUC-Atr-002698	Amborella trichopoda	26.42	9.00e-09	54.30
IUUC-Aca-005039	Anolis carolinensis	35.26	1.00e-56	213.00
IUUC-Aly-006181	Arabidopsis lyrata	26.86	2.00e-19	90.10
IUUC-Ath-007438	Arabidopsis thaliana	27.14	2.00e-20	93.20
IUUC-Ame-010671	Astyanax mexicanus	56.50	6.00e-118	417.00
IUUC-Bta-012407	Bos taurus	73.80	4.00e-150	523.00
IUUC-Bdi-014735	Brachypodium distachyon	25.24	5.00e-15	75.10
IUUC-Bol-015493	Brassica oleracea	25.43	4.00e-21	95.50
IUUC-Bra-016933	Brassica rapa	27.17	1.00e-18	86.70
IUUC-Cja-019709	Callithrix jacchus	89.78	3.00e-172	597.00
IUUC-Cfa-020818	Canis familiaris	87.29	3.00e-177	613.00
IUUC-Cpo-022490	Cavia porcellus	85.59	2.00e-167	581.00
IUUC-Cre-022828	Chlamydomonas reinhardtii	39.22	1.00e-06	43.90
IUUC-Csa-023259	Chlorocebus sabaeus	92.09	0.00e+00	667.00
IUUC-Cho-024730	Choloepus hoffmanni	87.57	0.00e+00	634.00
IUUC-Cin-025301	Ciona intestinalis	28.36	1.00e-39	156.00
IUUC-Dre-028644	Danio rerio	56.78	1.00e-118	419.00
IUUC-Dno-028925	Dasypus novemcinctus	85.59	0.00e+00	627.00
IUUC-Dor-030692	Dipodomys ordii	85.59	2.00e-170	591.00
IUUC-Dme-031761	Drosophila melanogaster	29.47	2.00e-30	125.00
IUUC-Ete-032329	Echinops telfairi	75.71	1.00e-139	489.00
IUUC-Eca-034008	Equus caballus	82.77	7.00e-178	615.00
IUUC-Eeu-034895	Erinaceus europaeus	70.38	7.00e-108	383.00
IUUC-Fca-036104	Felis catus	87.01	1.00e-177	615.00
IUUC-Fal-036900	Ficedula albicollis	67.44	3.00e-125	441.00
IUUC-Gmo-039049	Gadus morhua	53.98	2.00e-97	348.00
IUUC-Gga-040254	Gallus gallus	65.82	6.00e-132	463.00
IUUC-Gac-042277	Gasterosteus aculeatus	54.24	8.00e-119	419.00
IUUC-Gma-043979	Glycine max	28.15	2.00e-18	86.30
IUUC-Ggo-045509	Gorilla gorilla	92.09	0.00e+00	667.00
IUUC-Hsa-046597	Homo sapiens	92.09	0.00e+00	667.00
IUUC-Hvu-047335	Hordeum vulgare	24.91	3.00e-17	82.00
IUUC-Itr-048691	Ictidomys tridecemlineatus	86.72	2.00e-172	598.00
IUUC-Lch-050344	Latimeria chalumnae	63.28	9.00e-133	466.00
IUUC-Loc-052376	Lepisosteus oculatus	62.43	1.00e-136	479.00
IUUC-Laf-054414	Loxodonta africana	87.29	0.00e+00	637.00
IUUC-Mcc-054604	Macaca mulatta	91.81	0.00e+00	666.00
IUUC-Meu-056087	Macropus eugenii	78.25	2.00e-157	548.00
IUUC-Mtr-057779	Medicago truncatula	26.69	9.00e-17	80.90
IUUC-Mga-060188	Meleagris gallopavo	66.56	2.00e-129	455.00
IUUC-Mmr-060704	Microcebus murinus	89.27	0.00e+00	648.00
IUUC-Mdo-062842	Monodelphis domestica	77.97	3.00e-150	524.00
IUUC-Mmu-064324	Mus musculus	83.33	5.00e-163	566.00
IUUC-Mpu-065940	Mustela putorius furo	83.62	3.00e-164	570.00
IUUC-Mlu-067028	Myotis lucifugus	86.16	0.00e+00	628.00
IUUC-Opr-070827	Ochotona princeps	81.07	2.00e-172	598.00
IUUC-Ont-072008	Oreochromis niloticus	56.50	8.00e-124	436.00
IUUC-Oan-072935	Ornithorhynchus anatinus	73.16	2.00e-153	535.00
IUUC-Ocu-074526	Oryctolagus cuniculus	85.88	7.00e-169	586.00
IUUC-Obr-076592	Oryza brachyantha	25.43	6.00e-19	88.20
IUUC-Ogl-077732	Oryza glaberrima	25.80	1.00e-18	87.40
IUUC-Oin-080188	Oryza indica	25.80	1.00e-18	87.40
IUUC-Olo-080705	Oryza longistaminata	26.05	2.00e-13	70.90
IUUC-Ola-087288	Oryzias latipes	53.11	2.00e-112	399.00
IUUC-Oga-088402	Otolemur garnettii	87.57	0.00e+00	639.00
IUUC-Oar-089851	Ovis aries	77.44	3.00e-72	263.00
IUUC-Ptr-091226	Pan troglodytes	91.81	0.00e+00	666.00
IUUC-Pan-092575	Papio anubis	91.53	0.00e+00	665.00
IUUC-Psi-094062	Pelodiscus sinensis	71.19	2.00e-151	528.00
IUUC-Pma-094501	Petromyzon marinus	32.87	7.00e-37	147.00
IUUC-Ppa-095285	Physcomitrella patens	25.31	8.00e-13	67.80
IUUC-Pfo-096146	Poecilia formosa	52.26	2.00e-108	385.00
IUUC-Pab-098524	Pongo abelii	91.81	0.00e+00	667.00
IUUC-Pop-099864	Populus trichocarpa	28.21	2.00e-18	85.90
IUUC-Pca-100314	Procavia capensis	85.88	0.00e+00	629.00
IUUC-Ppe-101663	Prunus persica	26.37	1.00e-14	73.90
IUUC-Pva-102947	Pteropus vampyrus	85.88	0.00e+00	628.00
IUUC-Rno-105024	Rattus norvegicus	83.62	2.00e-166	578.00
IUUC-Sha-107500	Sarcophilus harrisii	60.78	6.00e-108	383.00
IUUC-Smo-109194	Selaginella moellendorffii	25.14	2.00e-17	83.20
IUUC-Sit-109922	Setaria italica	24.20	7.00e-18	84.30
IUUC-Sly-111826	Solanum lycopersicum	24.70	3.00e-17	82.80
IUUC-Stu-112907	Solanum tuberosum	24.32	3.00e-16	79.00
IUUC-Sar-113522	Sorex araneus	82.48	1.00e-151	528.00
IUUC-Sbi-114536	Sorghum bicolor	25.80	1.00e-19	90.50
IUUC-Ssc-115445	Sus scrofa	87.57	5.00e-171	593.00
IUUC-Tgu-116551	Taeniopygia guttata	66.38	4.00e-121	427.00
IUUC-Tru-118407	Takifugu rubripes	51.69	4.00e-101	360.00
IUUC-Tsy-118794	Tarsius syrichta	85.59	4.00e-179	620.00
IUUC-Tni-120128	Tetraodon nigroviridis	56.30	2.00e-78	285.00
IUUC-Tca-121508	Theobroma cacao	25.57	7.00e-19	87.80
IUUC-Tae-125185	Triticum aestivum	24.14	2.00e-18	86.30
IUUC-Tur-126470	Triticum urartu	23.85	2.00e-18	85.90
IUUC-Tbe-127432	Tupaia belangeri	89.27	1.00e-171	595.00
IUUC-Ttr-128573	Tursiops truncatus	83.62	5.00e-172	596.00
IUUC-Vpa-130583	Vicugna pacos	84.71	4.00e-160	556.00
IUUC-Vvi-131710	Vitis vinifera	26.12	2.00e-16	79.70
IUUC-Xtr-132009	Xenopus tropicalis	56.06	9.00e-122	429.00
IUUC-Xma-134121	Xiphophorus maculatus	53.24	1.00e-113	402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence