iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-14	53.1	196	231
UBD/Beta-Prp	5.90e-40	137.7	17	263

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sdtllvsGsdDgtikvWDlrtgvllks 38
           + v+++af sd++++s    g++++WD  tg+l+ks
   Q: 196  CIVWGVAFlSDGTVISVDSVGKVQLWDSATGTLVKS 231
           56899999*99888999999**********999875 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sghea.evtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           s i+cv++ ++++ la++ +dgt+++++++   + +++  ghe+ ++ a+++ + +  l +++  + i  +dl++  + +tl +    +
   Q: 17   SGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYFQEKFfPGHESrGTEALCWAEGQ-RLFSAGLNGEILEYDLQALNIKYTLDAFGGPI 104
           5689******************************9999988865279999999998.77777777777779****************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl...tgghtds 182
           +s++ spsg+ l++G +d  ++++++  ++   +  ++ +++ + ++++hp g  +++Gs D  + ++d+k+g++ r++   +  ++  
   Q: 105  WSMTASPSGSQLLVGCEDGSVKLFEVTPDKIQFArNFDRQKSRILSLSWHPAGTHVAAGSIDY-ISVFDVKSGSITRKMvldR--QHLG 190
           **************************9888765559999999********************7.8**************9752..4444 PP
   S: 183  vysls.......fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           v++         f s+g  ++s++  g+v+lwd  tg+ v++    ++ v+s+++ ++++ +v+g+++g+++ +
   Q: 191  VTKSRcivwgvaFLSDG-TVISVDSVGKVQLWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHF 263
           44444455666788887.9****************************************************977 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MGEFKVHRVR FFNYVPSGIR CVAYNNQSNR LAVSRTDGTV EIYNLSANYF QEKFFPGHES 60
RGTEALCWAE GQRLFSAGLN GEILEYDLQA LNIKYTLDAF GGPIWSMTAS PSGSQLLVGC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGACGGAG CTATAGAGTG CGCACGCGCG CACGTGGGAC CGGGGCGGAG AGAGGCGAGG 60
TCCCGGGTAG CGAGTGCCTG GCGGTAGGTG AGTTCGGGGA GAATCCCCGG GGGTAGCTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005694--C:chromosome
GO:0001650--C:fibrillar center
GO:0005730--C:nucleolus
GO:0034455--C:t-UTP complex
GO:0003723--F:RNA binding
GO:0030490--P:maturation of SSU-rRNA
GO:0006355--P:regulation of transcription, DNA-templated

KEGG

rno:291987

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001161	Aegilops tauschii	25.35	8.00e-46	178.00
IUUC-Aml-001310	Ailuropoda melanoleuca	91.55	0.00e+00	1334.00
IUUC-Atr-003076	Amborella trichopoda	23.49	8.00e-35	142.00
IUUC-Apl-003367	Anas platyrhynchos	57.14	3.00e-55	207.00
IUUC-Aca-004429	Anolis carolinensis	60.05	3.00e-142	497.00
IUUC-Aly-006271	Arabidopsis lyrata	23.22	9.00e-41	162.00
IUUC-Ath-007331	Arabidopsis thaliana	24.34	2.00e-38	154.00
IUUC-Ago-007843	Ashbya gossypii	25.16	9.00e-40	158.00
IUUC-Acl-008229	Aspergillus clavatus	25.88	2.00e-39	158.00
IUUC-Afl-008438	Aspergillus flavus	26.57	2.00e-39	157.00
IUUC-Afu-008910	Aspergillus fumigatus	25.14	7.00e-36	146.00
IUUC-Ani-009321	Aspergillus nidulans	29.51	3.00e-39	157.00
IUUC-Ang-009592	Aspergillus niger	26.59	2.00e-41	164.00
IUUC-Aor-010220	Aspergillus oryzae	26.27	2.00e-39	157.00
IUUC-Ate-010317	Aspergillus terreus	26.84	1.00e-38	155.00
IUUC-Ame-010957	Astyanax mexicanus	53.78	0.00e+00	772.00
IUUC-Bgr-012057	Blumeria graminis	26.74	2.00e-37	150.00
IUUC-Bta-012473	Bos taurus	88.21	0.00e+00	1286.00
IUUC-Bdi-014203	Brachypodium distachyon	23.47	2.00e-39	157.00
IUUC-Bol-016163	Brassica oleracea	24.64	2.00e-47	184.00
IUUC-Bra-017482	Brassica rapa	23.77	2.00e-46	181.00
IUUC-Cja-019942	Callithrix jacchus	89.80	0.00e+00	1312.00
IUUC-Cfa-020549	Canis familiaris	91.49	0.00e+00	934.00
IUUC-Cpo-022088	Cavia porcellus	91.84	0.00e+00	1315.00
IUUC-Csa-023773	Chlorocebus sabaeus	90.96	0.00e+00	1325.00
IUUC-Cho-024302	Choloepus hoffmanni	87.87	0.00e+00	1047.00
IUUC-Cin-025384	Ciona intestinalis	33.33	4.00e-114	405.00
IUUC-Dre-027460	Danio rerio	53.42	0.00e+00	765.00
IUUC-Dno-029594	Dasypus novemcinctus	89.22	0.00e+00	1261.00
IUUC-Dor-030564	Dipodomys ordii	87.95	0.00e+00	805.00
IUUC-Dse-031179	Dothistroma septosporum	25.76	4.00e-35	143.00
IUUC-Dme-031603	Drosophila melanogaster	24.36	9.00e-57	214.00
IUUC-Ete-032655	Echinops telfairi	82.65	0.00e+00	1189.00
IUUC-Eca-033838	Equus caballus	91.11	0.00e+00	1327.00
IUUC-Eeu-034548	Erinaceus europaeus	87.03	0.00e+00	1262.00
IUUC-Fca-035715	Felis catus	91.11	0.00e+00	1328.00
IUUC-Fal-037394	Ficedula albicollis	57.21	0.00e+00	755.00
IUUC-Gmo-039235	Gadus morhua	47.81	0.00e+00	680.00
IUUC-Ggr-040043	Gaeumannomyces graminis	26.21	1.00e-31	132.00
IUUC-Gga-041172	Gallus gallus	60.32	0.00e+00	870.00
IUUC-Gac-042466	Gasterosteus aculeatus	53.56	0.00e+00	764.00
IUUC-Gma-044222	Glycine max	25.04	1.00e-41	165.00
IUUC-Ggo-045416	Gorilla gorilla	87.76	0.00e+00	1265.00
IUUC-Hsa-046115	Homo sapiens	90.99	0.00e+00	1290.00
IUUC-Hvu-047229	Hordeum vulgare	24.39	4.00e-43	169.00
IUUC-Itr-048015	Ictidomys tridecemlineatus	91.25	0.00e+00	1330.00
IUUC-Kpa-049370	Komagataella pastoris	20.67	4.00e-30	126.00
IUUC-Lch-050153	Latimeria chalumnae	58.08	0.00e+00	828.00
IUUC-Lpe-051220	Leersia perrieri	24.15	7.00e-45	175.00
IUUC-Loc-052617	Lepisosteus oculatus	54.03	0.00e+00	795.00
IUUC-Laf-053613	Loxodonta africana	88.78	0.00e+00	1287.00
IUUC-Mcc-055707	Macaca mulatta	90.57	0.00e+00	1286.00
IUUC-Meu-056800	Macropus eugenii	66.61	0.00e+00	793.00
IUUC-Mor-057245	Magnaporthe oryzae	26.72	6.00e-29	122.00
IUUC-Mpo-057446	Magnaporthe poae	26.26	7.00e-31	129.00
IUUC-Mtr-058748	Medicago truncatula	23.70	1.00e-42	168.00
IUUC-Mga-060018	Meleagris gallopavo	59.85	0.00e+00	839.00
IUUC-Mmr-061115	Microcebus murinus	90.52	0.00e+00	1297.00
IUUC-Mdo-062235	Monodelphis domestica	76.38	0.00e+00	1129.00
IUUC-Mmu-063158	Mus musculus	97.23	0.00e+00	1399.00
IUUC-Mac-065380	Musa acuminata	24.73	6.00e-53	202.00
IUUC-Mpu-065805	Mustela putorius furo	90.96	0.00e+00	1328.00
IUUC-Mlu-066951	Myotis lucifugus	89.21	0.00e+00	1298.00
IUUC-Nfi-068295	Neosartorya fischeri	25.78	3.00e-37	150.00
IUUC-Ncr-068880	Neurospora crassa	26.03	8.00e-37	149.00
IUUC-Nle-069657	Nomascus leucogenys	91.40	0.00e+00	1336.00
IUUC-Opr-070250	Ochotona princeps	88.63	0.00e+00	1278.00
IUUC-Ont-072642	Oreochromis niloticus	51.82	0.00e+00	727.00
IUUC-Ocu-074741	Oryctolagus cuniculus	90.09	0.00e+00	1312.00
IUUC-Oba-074974	Oryza barthii	23.69	5.00e-45	176.00
IUUC-Obr-076586	Oryza brachyantha	25.27	6.00e-42	165.00
IUUC-Ogl-077782	Oryza glaberrima	24.15	2.00e-47	184.00
IUUC-Ogu-078333	Oryza glumaepatula	24.45	5.00e-43	169.00
IUUC-Oin-079852	Oryza indica	24.27	1.00e-48	188.00
IUUC-Olo-080370	Oryza longistaminata	26.57	5.00e-39	155.00
IUUC-Ome-081442	Oryza meridionalis	24.07	6.00e-48	186.00
IUUC-Oni-082341	Oryza nivara	24.45	3.00e-43	170.00
IUUC-Opu-083824	Oryza punctata	23.82	4.00e-46	179.00
IUUC-Oru-084827	Oryza rufipogon	24.02	1.00e-46	181.00
IUUC-Osa-085742	Oryza sativa	24.18	4.00e-49	189.00
IUUC-Ola-086466	Oryzias latipes	53.54	0.00e+00	744.00
IUUC-Olu-087761	Ostreococcus lucimarinus	24.85	3.00e-51	196.00
IUUC-Oga-088721	Otolemur garnettii	83.50	0.00e+00	1168.00
IUUC-Oar-089532	Ovis aries	89.07	0.00e+00	1300.00
IUUC-Ptr-091604	Pan troglodytes	91.11	0.00e+00	1329.00
IUUC-Pan-092060	Papio anubis	93.30	0.00e+00	766.00
IUUC-Psi-093070	Pelodiscus sinensis	60.79	0.00e+00	853.00
IUUC-Pma-094201	Petromyzon marinus	49.38	1.00e-139	489.00
IUUC-Ppa-095599	Physcomitrella patens	28.06	2.00e-32	134.00
IUUC-Pfo-097207	Poecilia formosa	51.09	0.00e+00	717.00
IUUC-Pab-097746	Pongo abelii	91.11	0.00e+00	1327.00
IUUC-Pop-099669	Populus trichocarpa	24.24	3.00e-52	200.00
IUUC-Pca-100562	Procavia capensis	80.29	0.00e+00	915.00
IUUC-Ppe-101747	Prunus persica	23.33	1.00e-48	187.00
IUUC-Pva-103054	Pteropus vampyrus	90.38	0.00e+00	1321.00
IUUC-Pte-104064	Pyrenophora teres	25.55	5.00e-29	123.00
IUUC-Pyt-104595	Pyrenophora triticirepentis	26.08	4.00e-31	130.00
IUUC-Sce-106369	Saccharomyces cerevisiae	23.36	1.00e-42	168.00
IUUC-Sha-107149	Sarcophilus harrisii	75.80	0.00e+00	1126.00
IUUC-Sja-107777	Schizosaccharomyces japonicus	28.30	3.00e-65	243.00
IUUC-Spo-108372	Schizosaccharomyces pombe	28.57	3.00e-69	256.00
IUUC-Ssl-108650	Sclerotinia sclerotiorum	27.52	2.00e-42	167.00
IUUC-Smo-108851	Selaginella moellendorffii	24.03	2.00e-53	204.00
IUUC-Sit-110454	Setaria italica	25.00	4.00e-42	166.00
IUUC-Sly-111875	Solanum lycopersicum	24.52	2.00e-49	191.00
IUUC-Stu-112275	Solanum tuberosum	23.46	1.00e-43	171.00
IUUC-Sar-113254	Sorex araneus	77.27	0.00e+00	687.00
IUUC-Sbi-114624	Sorghum bicolor	24.73	4.00e-41	162.00
IUUC-Sre-114985	Sporisorium reilianum	20.06	2.00e-16	81.60
IUUC-Tgu-117407	Taeniopygia guttata	58.60	6.00e-144	503.00
IUUC-Tru-118733	Takifugu rubripes	47.74	0.00e+00	685.00
IUUC-Tsy-119213	Tarsius syrichta	79.94	0.00e+00	1023.00
IUUC-Tni-120894	Tetraodon nigroviridis	48.50	1.00e-98	352.00
IUUC-Tca-121606	Theobroma cacao	23.90	1.00e-43	171.00
IUUC-Tre-121958	Trichoderma reesei	27.00	9.00e-38	152.00
IUUC-Tvi-122290	Trichoderma virens	26.71	1.00e-38	154.00
IUUC-Tae-125538	Triticum aestivum	25.04	2.00e-45	177.00
IUUC-Tme-126995	Tuber melanosporum	25.71	2.00e-32	134.00
IUUC-Tbe-127605	Tupaia belangeri	74.29	5.00e-69	255.00
IUUC-Ttr-128720	Tursiops truncatus	88.92	0.00e+00	1288.00
IUUC-Uma-129564	Ustilago maydis	20.84	2.00e-15	78.20
IUUC-Vpa-130412	Vicugna pacos	89.43	3.00e-134	472.00
IUUC-Vvi-131256	Vitis vinifera	25.36	7.00e-49	189.00
IUUC-Xtr-131828	Xenopus tropicalis	55.94	0.00e+00	804.00
IUUC-Xma-133394	Xiphophorus maculatus	52.17	0.00e+00	729.00
IUUC-Yli-134565	Yarrowia lipolytica	28.35	1.00e-34	141.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence