iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037147

Ensembl Protein ID

ENSFALP00000008653.1

UniProt Accession

U3K0U9; U3K0U9_FICAL

Genbank Protein ID

ENSFALP00000008653

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010311

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000008300.1	ENSFALT00000008691.1	ENSFALP00000008653.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.00e-06	25.8	196	237

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle +   ++++v pC H fh++C+  w        ++ +CP Cr
   Q: 196  CAICLEKYidGEELRVIPCTHRFHKKCVDPW------LLQHHTCPHCR 237
           ********66334******************......9999******8 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

LFQMHPLGLC NSNDEEDLYE YGWVGVVKLE QPELEPKPCL TVLGKAKRAV QRGATAVIFD 60
VSENPDAIDQ LNQGSEDPLK RPVVYVKGAD AVKLMNIVNK QKVARARIQH RPPRQPTEYF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTTTCAGA TGCATCCACT TGGACTGTGT AATAGCAATG ATGAGGAAGA CCTGTATGAA 60
TATGGCTGGG TAGGAGTGGT GAAATTGGAA CAGCCAGAGC TGGAGCCCAA GCCATGCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	72.67	0.00e+00	982.00
IUUC-Apl-004188	Anas platyrhynchos	92.83	0.00e+00	1426.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	4.00e-15	73.60
IUUC-Ath-007372	Arabidopsis thaliana	42.17	4.00e-15	73.60
IUUC-Ame-011764	Astyanax mexicanus	65.36	0.00e+00	765.00
IUUC-Bta-012478	Bos taurus	56.72	1.00e-155	543.00
IUUC-Bol-015945	Brassica oleracea	42.67	2.00e-14	73.20
IUUC-Bra-017899	Brassica rapa	42.67	2.00e-14	73.20
IUUC-Cja-019504	Callithrix jacchus	71.12	0.00e+00	1038.00
IUUC-Cfa-020048	Canis familiaris	71.12	0.00e+00	1013.00
IUUC-Cpo-021725	Cavia porcellus	66.91	0.00e+00	943.00
IUUC-Csa-023586	Chlorocebus sabaeus	70.64	0.00e+00	988.00
IUUC-Cho-024867	Choloepus hoffmanni	82.16	3.00e-173	602.00
IUUC-Cin-025569	Ciona intestinalis	48.56	6.00e-58	218.00
IUUC-Csv-025869	Ciona savignyi	46.50	2.00e-51	196.00
IUUC-Dre-027553	Danio rerio	65.88	0.00e+00	835.00
IUUC-Dno-029370	Dasypus novemcinctus	70.93	0.00e+00	962.00
IUUC-Dor-030816	Dipodomys ordii	67.33	0.00e+00	907.00
IUUC-Ete-033060	Echinops telfairi	66.25	0.00e+00	731.00
IUUC-Eca-034044	Equus caballus	72.15	0.00e+00	1030.00
IUUC-Eeu-034591	Erinaceus europaeus	53.11	3.00e-98	352.00
IUUC-Fca-036000	Felis catus	70.89	0.00e+00	1020.00
IUUC-Gmo-039099	Gadus morhua	51.37	6.00e-125	441.00
IUUC-Gga-041243	Gallus gallus	91.03	0.00e+00	1187.00
IUUC-Gac-041340	Gasterosteus aculeatus	53.74	9.00e-129	453.00
IUUC-Gma-044387	Glycine max	49.09	2.00e-14	72.00
IUUC-Ggo-044953	Gorilla gorilla	71.60	0.00e+00	1024.00
IUUC-Hsa-046484	Homo sapiens	71.51	0.00e+00	1032.00
IUUC-Hvu-047249	Hordeum vulgare	43.21	5.00e-12	63.20
IUUC-Itr-048470	Ictidomys tridecemlineatus	70.76	0.00e+00	1008.00
IUUC-Lch-050004	Latimeria chalumnae	63.03	0.00e+00	762.00
IUUC-Lpe-051459	Leersia perrieri	40.66	3.00e-13	68.90
IUUC-Loc-051830	Lepisosteus oculatus	66.95	0.00e+00	857.00
IUUC-Laf-053975	Loxodonta africana	71.29	0.00e+00	991.00
IUUC-Mcc-055302	Macaca mulatta	70.05	0.00e+00	966.00
IUUC-Meu-056263	Macropus eugenii	73.39	0.00e+00	785.00
IUUC-Mtr-058744	Medicago truncatula	39.56	1.00e-13	68.90
IUUC-Mga-059706	Meleagris gallopavo	91.74	0.00e+00	1429.00
IUUC-Mmr-061372	Microcebus murinus	69.73	0.00e+00	946.00
IUUC-Mdo-062651	Monodelphis domestica	63.45	0.00e+00	857.00
IUUC-Mmu-064339	Mus musculus	71.07	0.00e+00	959.00
IUUC-Mac-064852	Musa acuminata	56.86	4.00e-13	69.30
IUUC-Mpu-066211	Mustela putorius furo	69.59	0.00e+00	981.00
IUUC-Mlu-067058	Myotis lucifugus	69.92	0.00e+00	937.00
IUUC-Nle-069886	Nomascus leucogenys	71.22	0.00e+00	1003.00
IUUC-Opr-070218	Ochotona princeps	69.31	0.00e+00	857.00
IUUC-Ont-072483	Oreochromis niloticus	62.38	0.00e+00	830.00
IUUC-Oan-073718	Ornithorhynchus anatinus	71.95	0.00e+00	918.00
IUUC-Ocu-073847	Oryctolagus cuniculus	68.49	0.00e+00	843.00
IUUC-Ola-087358	Oryzias latipes	66.49	0.00e+00	826.00
IUUC-Oga-088362	Otolemur garnettii	70.82	0.00e+00	1024.00
IUUC-Oar-090197	Ovis aries	94.12	1.00e-93	337.00
IUUC-Ptr-091350	Pan troglodytes	71.28	0.00e+00	1031.00
IUUC-Pan-091700	Papio anubis	69.80	0.00e+00	962.00
IUUC-Psi-093301	Pelodiscus sinensis	80.90	0.00e+00	1236.00
IUUC-Ppa-095613	Physcomitrella patens	43.33	2.00e-13	69.30
IUUC-Pfo-096917	Poecilia formosa	65.98	0.00e+00	815.00
IUUC-Pab-097932	Pongo abelii	72.06	0.00e+00	1054.00
IUUC-Pop-099512	Populus trichocarpa	49.09	2.00e-14	71.60
IUUC-Pca-101054	Procavia capensis	81.43	0.00e+00	832.00
IUUC-Ppe-101991	Prunus persica	32.43	1.00e-13	68.90
IUUC-Pva-102879	Pteropus vampyrus	71.85	0.00e+00	1017.00
IUUC-Sha-106507	Sarcophilus harrisii	53.95	1.00e-175	609.00
IUUC-Sly-111371	Solanum lycopersicum	37.00	3.00e-13	68.20
IUUC-Stu-112741	Solanum tuberosum	39.60	9.00e-14	69.70
IUUC-Sar-113182	Sorex araneus	80.51	2.00e-106	380.00
IUUC-Ssc-115966	Sus scrofa	69.48	0.00e+00	858.00
IUUC-Tgu-116864	Taeniopygia guttata	96.93	0.00e+00	1159.00
IUUC-Tru-118502	Takifugu rubripes	63.44	0.00e+00	795.00
IUUC-Tsy-119210	Tarsius syrichta	73.79	0.00e+00	967.00
IUUC-Tni-120344	Tetraodon nigroviridis	56.30	6.00e-142	497.00
IUUC-Tca-120911	Theobroma cacao	47.54	2.00e-13	69.30
IUUC-Tbe-127735	Tupaia belangeri	69.14	1.00e-102	367.00
IUUC-Ttr-128714	Tursiops truncatus	61.47	0.00e+00	802.00
IUUC-Vvi-131731	Vitis vinifera	38.75	3.00e-13	68.20
IUUC-Xtr-132280	Xenopus tropicalis	59.43	0.00e+00	711.00
IUUC-Xma-134192	Xiphophorus maculatus	65.85	0.00e+00	818.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence