iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088501

Ensembl Protein ID

ENSOGAP00000006368.2

UniProt Accession

H0WVM2; H0WVM2_OTOGA

Genbank Protein ID

ENSOGAP00000006368

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03089313

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000007102.2	ENSOGAT00000007111.2	ENSOGAP00000006368.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.30e-22	78.4	117	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 117  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 163
           8********988.6*******************.*******7.******5 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

QKPNLTTDTK DKEYRPHDIP QRQSVQPSET CPPARRAKRM RAEAMNIKIE PEETTEARTH 60
NLRRRMGCPT PKRDNEKEMK NNVKQEPFEK KDYIIENEKE KPKSRSKKTT NAVDLYVCLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAAGCCAA ACCTGACCAC AGACACAAAA GACAAGGAGT ACAGACCCCA TGATATTCCT 60
CAGAGGCAGT CTGTGCAGCC CTCAGAAACA TGCCCTCCGG CCCGAAGAGC AAAACGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001963	Ailuropoda melanoleuca	92.23	0.00e+00	2391.00
IUUC-Apl-003770	Anas platyrhynchos	81.23	0.00e+00	1812.00
IUUC-Aca-004867	Anolis carolinensis	77.53	0.00e+00	2060.00
IUUC-Ame-010620	Astyanax mexicanus	57.51	0.00e+00	1521.00
IUUC-Bta-012733	Bos taurus	87.27	0.00e+00	2268.00
IUUC-Bol-015336	Brassica oleracea	36.45	3.00e-14	75.50
IUUC-Cja-019050	Callithrix jacchus	92.38	0.00e+00	2440.00
IUUC-Cfa-021015	Canis familiaris	92.23	0.00e+00	2382.00
IUUC-Cpo-022340	Cavia porcellus	92.23	0.00e+00	2362.00
IUUC-Cre-022637	Chlamydomonas reinhardtii	48.21	3.00e-08	49.70
IUUC-Csa-023441	Chlorocebus sabaeus	93.19	0.00e+00	2404.00
IUUC-Cho-024823	Choloepus hoffmanni	89.85	0.00e+00	1234.00
IUUC-Dre-027707	Danio rerio	56.76	0.00e+00	1438.00
IUUC-Dno-028978	Dasypus novemcinctus	91.94	0.00e+00	2376.00
IUUC-Dor-030854	Dipodomys ordii	81.62	0.00e+00	1790.00
IUUC-Ete-032760	Echinops telfairi	85.77	0.00e+00	1727.00
IUUC-Eca-034370	Equus caballus	92.38	0.00e+00	2318.00
IUUC-Eeu-035012	Erinaceus europaeus	80.69	0.00e+00	1026.00
IUUC-Fca-035494	Felis catus	92.82	0.00e+00	2383.00
IUUC-Fal-037631	Ficedula albicollis	79.04	0.00e+00	2066.00
IUUC-Gmo-039522	Gadus morhua	53.85	0.00e+00	1329.00
IUUC-Gga-040802	Gallus gallus	79.01	0.00e+00	2005.00
IUUC-Gac-041563	Gasterosteus aculeatus	58.79	0.00e+00	1469.00
IUUC-Ggo-044856	Gorilla gorilla	74.34	0.00e+00	1776.00
IUUC-Hsa-045888	Homo sapiens	90.70	0.00e+00	2412.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	9.00e-16	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	92.75	0.00e+00	2363.00
IUUC-Lch-050483	Latimeria chalumnae	61.88	0.00e+00	1644.00
IUUC-Loc-052550	Lepisosteus oculatus	66.42	0.00e+00	1712.00
IUUC-Laf-053761	Loxodonta africana	91.78	0.00e+00	2379.00
IUUC-Mcc-055505	Macaca mulatta	90.92	0.00e+00	2415.00
IUUC-Mga-059358	Meleagris gallopavo	78.15	0.00e+00	2066.00
IUUC-Mmr-060863	Microcebus murinus	93.57	0.00e+00	2416.00
IUUC-Mdo-061957	Monodelphis domestica	86.75	0.00e+00	2277.00
IUUC-Mmu-063944	Mus musculus	89.27	0.00e+00	2293.00
IUUC-Mac-065069	Musa acuminata	36.04	3.00e-08	55.80
IUUC-Mpu-066719	Mustela putorius furo	90.06	0.00e+00	2365.00
IUUC-Mlu-068086	Myotis lucifugus	83.12	0.00e+00	2167.00
IUUC-Nle-069256	Nomascus leucogenys	90.92	0.00e+00	2415.00
IUUC-Ont-071756	Oreochromis niloticus	58.55	0.00e+00	1497.00
IUUC-Oan-073568	Ornithorhynchus anatinus	85.94	0.00e+00	2261.00
IUUC-Ocu-073961	Oryctolagus cuniculus	88.30	0.00e+00	2303.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	1.00e-16	82.00
IUUC-Olo-080668	Oryza longistaminata	38.83	4.00e-16	81.60
IUUC-Osa-085487	Oryza sativa	38.83	1.00e-16	82.00
IUUC-Ola-086448	Oryzias latipes	57.50	0.00e+00	1459.00
IUUC-Oar-090162	Ovis aries	86.97	0.00e+00	2264.00
IUUC-Ptr-090816	Pan troglodytes	90.84	0.00e+00	2420.00
IUUC-Pan-092764	Papio anubis	93.34	0.00e+00	2408.00
IUUC-Psi-093918	Pelodiscus sinensis	79.19	0.00e+00	2116.00
IUUC-Ppa-095839	Physcomitrella patens	53.45	1.00e-15	79.70
IUUC-Pfo-096672	Poecilia formosa	58.00	0.00e+00	1429.00
IUUC-Pab-097854	Pongo abelii	87.79	0.00e+00	1741.00
IUUC-Pca-100241	Procavia capensis	86.14	0.00e+00	1676.00
IUUC-Pva-103035	Pteropus vampyrus	80.90	0.00e+00	1863.00
IUUC-Rno-105574	Rattus norvegicus	87.80	0.00e+00	2240.00
IUUC-Sar-113477	Sorex araneus	85.43	0.00e+00	2035.00
IUUC-Ssc-116132	Sus scrofa	89.75	0.00e+00	1977.00
IUUC-Tgu-117452	Taeniopygia guttata	79.45	0.00e+00	2065.00
IUUC-Tru-117561	Takifugu rubripes	58.26	0.00e+00	1330.00
IUUC-Tsy-119271	Tarsius syrichta	90.47	0.00e+00	2063.00
IUUC-Tni-119650	Tetraodon nigroviridis	56.38	0.00e+00	1425.00
IUUC-Tbe-127890	Tupaia belangeri	86.50	0.00e+00	1440.00
IUUC-Ttr-128546	Tursiops truncatus	83.74	0.00e+00	1558.00
IUUC-Vpa-130432	Vicugna pacos	84.40	0.00e+00	1466.00
IUUC-Xtr-132008	Xenopus tropicalis	66.22	0.00e+00	1727.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence