iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000026990.8	ENSDART00000039174.7	ENSDARP00000028820.7
ENSDARG00000026990.8	ENSDART00000167279.1	ENSDARP00000139639.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.60e-21	75.9	65	130
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.10e-09	36.0	164	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dvil+v+ + f++h++vLaa+S++F+a+f ++l+e++ ++ v+ik+++++ +r ll++ Yt+k+++
   Q: 65   TDVILNVQSQSFKCHRVVLAAASHYFRAMFCNDLREKH-EENVNIKGIDADTMRILLDYTYTSKVTI 130
           7***********************************98.************************9976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           +eNc+gil++Ad ++++ Lk +++++i ++F
   Q: 164  PENCVGILHLADVHSLESLKTQVHSYIVQNF 194
           89***************************** PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MADAPQNDSE CPSSGQTEAS AGGLSLLESS TQENQEDGQV LFEDSVFAGC LQDGLHSLCL 60
EDSLTDVILN VQSQSFKCHR VVLAAASHYF RAMFCNDLRE KHEENVNIKG IDADTMRILL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCCACGATC TTGTGTAGCT GCAACACTGA ACTTGAGAGG TTTCTGCACT TCCTCTTTGT 60
AGGCCGTTAT AAAAACAGGA AGCGTACATG TTAGGAAAGA ACAATTCAGC TGTAGTTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

dre:368818

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	73.22	0.00e+00	892.00
IUUC-Apl-003490	Anas platyrhynchos	71.01	0.00e+00	903.00
IUUC-Aca-005136	Anolis carolinensis	73.47	0.00e+00	901.00
IUUC-Ame-010886	Astyanax mexicanus	72.80	0.00e+00	908.00
IUUC-Bta-013473	Bos taurus	73.04	0.00e+00	866.00
IUUC-Cja-018888	Callithrix jacchus	72.87	0.00e+00	885.00
IUUC-Cpo-021761	Cavia porcellus	67.42	0.00e+00	809.00
IUUC-Csa-023206	Chlorocebus sabaeus	70.20	0.00e+00	890.00
IUUC-Cin-025367	Ciona intestinalis	40.58	3.00e-129	455.00
IUUC-Csv-026076	Ciona savignyi	40.67	2.00e-122	432.00
IUUC-Dno-030045	Dasypus novemcinctus	73.04	0.00e+00	890.00
IUUC-Dor-030839	Dipodomys ordii	64.76	0.00e+00	799.00
IUUC-Eca-033608	Equus caballus	73.22	0.00e+00	870.00
IUUC-Eeu-034640	Erinaceus europaeus	69.33	0.00e+00	894.00
IUUC-Fca-036065	Felis catus	69.71	0.00e+00	888.00
IUUC-Fal-036949	Ficedula albicollis	71.81	0.00e+00	901.00
IUUC-Gmo-039661	Gadus morhua	60.88	4.00e-167	581.00
IUUC-Gga-040740	Gallus gallus	72.00	0.00e+00	903.00
IUUC-Gac-042413	Gasterosteus aculeatus	65.16	0.00e+00	774.00
IUUC-Ggo-045167	Gorilla gorilla	70.20	0.00e+00	890.00
IUUC-Hsa-046120	Homo sapiens	70.20	0.00e+00	890.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	70.03	0.00e+00	889.00
IUUC-Lch-049709	Latimeria chalumnae	72.98	0.00e+00	897.00
IUUC-Loc-052239	Lepisosteus oculatus	77.38	0.00e+00	908.00
IUUC-Laf-054511	Loxodonta africana	72.96	0.00e+00	892.00
IUUC-Mcc-055109	Macaca mulatta	70.20	0.00e+00	890.00
IUUC-Meu-056522	Macropus eugenii	62.87	8.00e-82	298.00
IUUC-Mga-060012	Meleagris gallopavo	70.46	0.00e+00	879.00
IUUC-Mmr-061364	Microcebus murinus	72.87	0.00e+00	887.00
IUUC-Mdo-063033	Monodelphis domestica	64.83	0.00e+00	780.00
IUUC-Mmu-063880	Mus musculus	69.87	0.00e+00	858.00
IUUC-Mlu-068233	Myotis lucifugus	73.25	0.00e+00	894.00
IUUC-Opr-070638	Ochotona princeps	68.47	0.00e+00	627.00
IUUC-Ont-071960	Oreochromis niloticus	62.36	0.00e+00	793.00
IUUC-Oan-073406	Ornithorhynchus anatinus	64.98	0.00e+00	808.00
IUUC-Ocu-074612	Oryctolagus cuniculus	72.87	0.00e+00	888.00
IUUC-Ola-087181	Oryzias latipes	62.14	0.00e+00	751.00
IUUC-Oga-088955	Otolemur garnettii	70.60	0.00e+00	885.00
IUUC-Oar-089682	Ovis aries	73.22	0.00e+00	867.00
IUUC-Ptr-090969	Pan troglodytes	70.20	0.00e+00	890.00
IUUC-Pan-092289	Papio anubis	70.20	0.00e+00	890.00
IUUC-Psi-093279	Pelodiscus sinensis	70.36	0.00e+00	895.00
IUUC-Pab-097957	Pongo abelii	73.46	0.00e+00	705.00
IUUC-Pca-100619	Procavia capensis	71.58	0.00e+00	883.00
IUUC-Pva-102533	Pteropus vampyrus	71.81	4.00e-141	495.00
IUUC-Rno-106111	Rattus norvegicus	69.71	0.00e+00	885.00
IUUC-Sha-106716	Sarcophilus harrisii	67.30	0.00e+00	809.00
IUUC-Smo-108752	Selaginella moellendorffii	24.79	2.00e-12	67.40
IUUC-Tgu-116839	Taeniopygia guttata	70.85	0.00e+00	900.00
IUUC-Tru-117792	Takifugu rubripes	64.41	0.00e+00	778.00
IUUC-Tsy-119609	Tarsius syrichta	57.43	3.00e-95	342.00
IUUC-Tni-119682	Tetraodon nigroviridis	62.03	0.00e+00	773.00
IUUC-Tme-127039	Tuber melanosporum	30.26	7.00e-14	73.20
IUUC-Tbe-127961	Tupaia belangeri	65.95	0.00e+00	793.00
IUUC-Ttr-128917	Tursiops truncatus	71.64	0.00e+00	717.00
IUUC-Vpa-130721	Vicugna pacos	72.10	0.00e+00	654.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence